Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(127 produtos)
- FOXO1(3 produtos)
- IAP(65 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(126 produtos)
- PDK(9 produtos)
- PERK(24 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(91 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5622 produtos de "Apoptose"
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SAHA-OH
CAS:<p>SAHA-OH selectively inhibits HDAC6 (IC50 = 23 nM) with 10-47x preference over HDACs 1, 2, 3, 8, and reduces inflammation and macrophage apoptosis.</p>Fórmula:C15H22N2O4Pureza:98%Cor e Forma:SolidPeso molecular:294.35BP-1-108
CAS:<p>BP-1-108 is a potent and selective STAT5 inhibitor.</p>Fórmula:C32H38N2O6SCor e Forma:SolidPeso molecular:578.72BIBU-1361 dihydrochloride
CAS:<p>BIBU-1361 dihydrochloride inhibits EGFR kinase, blocking MAPKK/MAPK activation.</p>Fórmula:C22H29Cl3FN7Cor e Forma:SolidPeso molecular:516.87Apoptosis inducer 6
CAS:<p>Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.</p>Fórmula:C27H26N4O3SCor e Forma:SolidPeso molecular:486.59MCL-1/BCL-2-IN-3
CAS:MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.Fórmula:C27H25BrN2O5SCor e Forma:SolidPeso molecular:569.47Apoptotic agent-3
CAS:<p>"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."</p>Fórmula:C31H21N5OSCor e Forma:SolidPeso molecular:511.6MBC-11
CAS:MBC-11: First bone-targeting bisphosphonate-etidronate conjugate with araC, may treat TIBD.Fórmula:C11H20N3O14P3Pureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:511.21ABD56
CAS:<p>ABD56 inhibits osteoclast formation and activity in vitro and in vivo.</p>Fórmula:C17H18O3Cor e Forma:SolidPeso molecular:270.32BMS-242
CAS:BMS-242 is an effective inhibitor of PD-1/PD-L1 interaction.Fórmula:C28H35NO4Pureza:98%Cor e Forma:SolidPeso molecular:449.58NHI-2
CAS:<p>NHI-2 is an LDHA inhibitor (IC50 14.7 µM) that blocks glycolysis, induces apoptosis and cell cycle arrest, and suppresses tumor growth in melanoma models.</p>Fórmula:C17H12F3NO3Pureza:99.981%Cor e Forma:SolidPeso molecular:335.28MEB55
CAS:<p>MEB55, an anticancer agent, acts by disrupting DNA repair and halting growth in prostate, colon, lung and breast cancer cells.</p>Fórmula:C22H17NO4SPureza:98%Cor e Forma:SolidPeso molecular:391.44Bax activator-1
CAS:<p>Bax activator-1 (compound 106) is a Bax activator. It induces Bax-dependent tumor cell apoptosis[1].</p>Fórmula:C29H36N4O3Cor e Forma:SolidPeso molecular:488.62p53 Activator 3
CAS:<p>Potent p53 activator, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>Fórmula:C30H37F3N4O4SCor e Forma:SolidPeso molecular:606.7Gea 3162
CAS:<p>GEA 3162 blocks ADP-induced platelet clumping in PRP and boosts cGMP in granulocytes and leukocytes.</p>Fórmula:C7H4Cl2N4OPureza:98%Cor e Forma:SolidPeso molecular:231.04Butyrolactone I
CAS:<p>Butyrolactone I (Olomoucin) inhibits CDKs, blocks cdc2 kinases, and shows antitumor activity in lung and prostate cancers.</p>Fórmula:C24H24O7Pureza:98%Cor e Forma:SolidPeso molecular:424.44CPI-7c
CAS:CPI-7c inhibits MDM2-p53 interaction and promotes MDM2 degradation.Fórmula:C22H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:358.39KS106
CAS:<p>KS106 inhibits ALDH (1A1: 334 nM, 2: 2137 nM, 3A1: 360 nM), has anti-cancer properties, raises ROS, and promotes aldehyde build-up.</p>Fórmula:C18H15BrF3N3O2SPureza:99.31%Cor e Forma:SolidPeso molecular:474.3WK-298
CAS:<p>WK-298 is an effective MDM2/MDMX-p53 interaction inhibitor.</p>Fórmula:C35H38Cl2N6OPureza:98%Cor e Forma:SolidPeso molecular:629.62A 410099.1
CAS:<p>A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.</p>Fórmula:C27H41ClN4O3Pureza:99.30%Cor e Forma:SolidPeso molecular:505.1Vin-F03
CAS:<p>Vin-F03 protects pancreatic β-cells in type 2 diabetes research with an EC50 of 0.27 μM and prevents STZ-induced apoptosis.</p>Fórmula:C22H29N3Cor e Forma:SolidPeso molecular:335.49GY1-22
CAS:<p>GY1-22, an inhibitor targeting the DNAJA1-mutP53 R175H interaction pocket, holds potential for cancer research applications.</p>Fórmula:C23H20N4OSCor e Forma:SolidPeso molecular:400.5CU-3
CAS:<p>CU-3 inhibits DGKalpha, reducing cancer growth and boosting anti-cancer immunity.</p>Fórmula:C16H12N2O4S3Pureza:98%Cor e Forma:SolidPeso molecular:392.47MK-28
CAS:MK-28 is a PERK agonist that reduces toxicity in a Huntington's disease model.MK-28 has a significant killing effect on MK28 gastric cancer cells.Fórmula:C24H20N4O2Cor e Forma:SolidPeso molecular:396.44Ro24-7429
CAS:<p>Ro24-7429: oral HIV-1 Tat antagonist, RUNX1 inhibitor with anti-HIV, antifibrotic, and anti-inflammatory properties.</p>Fórmula:C14H13ClN4Pureza:99.29% - 99.85%Cor e Forma:SolidPeso molecular:272.73Tubulin inhibitor 11
CAS:<p>Potent, oral Tubulin inhibitor 11 hinders polymerization, targets Colchicine site, induces mitotic block, and apoptosis.</p>Fórmula:C22H23N3O3SPureza:98.32%Cor e Forma:SoildPeso molecular:409.5LCS3
CAS:<p>LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3</p>Fórmula:C11H7ClN2O4Pureza:99.68%Cor e Forma:SolidPeso molecular:266.64Triciribine phosphate
CAS:Triciribine phosphate (VD 002) is an AKT inhibitor that inhibits neovascularization and can be used in the study of leukemia.Fórmula:C13H17N6O7PPureza:97.94%Cor e Forma:SolidPeso molecular:400.28CCT020312
CAS:<p>CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB.Cost-effective and quality-assured.</p>Fórmula:C31H30Br2N4O2Pureza:98.63%Cor e Forma:SolidPeso molecular:650.4A 419259 trihydrochloride
CAS:A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).Fórmula:C29H37Cl3N6OPureza:99.75% - 99.96%Cor e Forma:SolidPeso molecular:592Etomoxir
CAS:<p>Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a) (IC50=5-20 nM), inhibits fatty acid oxidation. High-Quality, Low-Cost!</p>Fórmula:C17H23ClO4Pureza:98% - 99.39%Cor e Forma:SolidPeso molecular:326.82STAT3-IN-13
CAS:<p>STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.</p>Fórmula:C21H20N6O3SPureza:98.89%Cor e Forma:SolidPeso molecular:436.49VAS 3947
CAS:<p>VAS 3947: NOX inhibitor, induces platelet apoptosis via UPR, not linked to NOX inhibition.</p>Fórmula:C14H10N6OSPureza:98.44%Cor e Forma:SolidPeso molecular:310.33Mepazine
CAS:<p>Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.</p>Fórmula:C19H22N2SPureza:99.88% - 99.92%Cor e Forma:SolidPeso molecular:310.46UK-101
CAS:<p>UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM</p>Fórmula:C25H48N2O5SiPureza:99.08% - 99.25%Cor e Forma:SolidPeso molecular:484.74HS-276
CAS:<p>HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.</p>Fórmula:C24H29N5O2Pureza:97.852% - 98.81%Cor e Forma:SolidPeso molecular:419.52AZA1
CAS:<p>AZA1 (Rac1/Cdc42-IN-1) is a potent dual inhibitor of Rac1 and Cdc42.</p>Fórmula:C22H20N6Pureza:99.75%Cor e Forma:SolidPeso molecular:368.43Trk-IN-9
CAS:<p>Trk-IN-9 is a TRK inhibitor with anticancer and antiproliferative activity and can be used in cancer research.</p>Fórmula:C23H24ClFN6OPureza:98.15%Cor e Forma:SolidPeso molecular:454.93Ro 08-2750
CAS:<p>Ro 08-2750: A non-peptide NGF inhibitor binding NGF (~1 µM IC50) & selectively inhibits p75NTR over TRKA and MSI RNA-binding (2.7 µM IC50).</p>Fórmula:C13H10N4O3Pureza:98.795%Cor e Forma:SolidPeso molecular:270.24TAI-1
CAS:<p>TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.</p>Fórmula:C24H21N3O3SPureza:99.58%Cor e Forma:SolidPeso molecular:431.51NLRP3/AIM2-IN-3
CAS:<p>NLRP3/AIM2-IN-3 selectively blocks NLRP3/AIM2 inflammasomes; IC50 for cell lysis is 0.077 μM, disrupting ASC oligomerization.</p>Fórmula:C16H14N2O2Pureza:97.04%Cor e Forma:SolidPeso molecular:266.29H2L5186303
CAS:<p>H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.</p>Fórmula:C26H20N2O8Pureza:98.19%Cor e Forma:SolidPeso molecular:488.45CCT018159
CAS:<p>CCT018159: ATP-competitive HSP90 inhibitor, IC50 3.2 μM (human), 6.6 μM (yeast), blocks invasion, angiogenesis, induces G1 arrest and apoptosis.</p>Fórmula:C20H20N2O4Pureza:98.78% - 99.79%Cor e Forma:SolidPeso molecular:352.38LDCA
CAS:<p>LDCA inhibits LDH-A, disrupts mitochondrial function, induces apoptosis in cancer cells, and is non-toxic.</p>Fórmula:C8H5Cl3FNOPureza:98.99%Cor e Forma:SolidPeso molecular:256.49N6-Cyclopentyladenosine
CAS:<p>N6-Cyclopentyladenosine (CPA) is a selective agonist of the adenosine A1 receptor and can be used to mimic the action of the adenosine A1 receptor, with Ki's of</p>Fórmula:C15H21N5O4Pureza:99.84%Cor e Forma:SolidPeso molecular:335.36Ro 90-7501
CAS:Ro 90-7501, an amyloid β42 (Aβ42) protofibril and TPR-dependent PP5 inhibitor, is a novel cervical cancer cell radiosensitizer that inhibits HCMV.Fórmula:C20H16N6Pureza:97.21% - 99.72%Cor e Forma:SolidPeso molecular:340.38TL4-12
CAS:TL4-12 is a MAP4K2 (GCK) inhibitor that inhibits IL-1 and TGFβ-induced p38 MAPK phosphorylation in vitro.Fórmula:C25H27F3N6O2Pureza:98.38%Cor e Forma:SolidPeso molecular:500.52CP 461
CAS:<p>CP 461 is a PDE2A inhibitor that promotes apoptosis in cancer cells without affecting normal cells or COX-1/2.</p>Fórmula:C25H22ClFN2OPureza:99.82%Cor e Forma:SolidPeso molecular:420.91Anticancer agent 110
CAS:<p>Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cells</p>Fórmula:C18H13FN6OSPureza:98%Cor e Forma:SolidPeso molecular:380.4OR-1896
CAS:OR-1896 is a PDE III inhibitor, a vasodilator with partial anti-inflammatory properties, and can be used to study heart failure and vascular dysfunction.Fórmula:C13H15N3O2Pureza:99.33%Cor e Forma:SolidPeso molecular:245.28Epristeride
CAS:Epristeride (ONO-9302) is a steroidal 5-alpha-reductase isoform 2 inhibitor that inhibits SR isoform 2. Epristeride reduces prostate size.Fórmula:C25H37NO3Pureza:98.12% - >99.99%Cor e Forma:SolidPeso molecular:399.57
