Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(127 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(90 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6170 produtos de "Apoptose"
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AC-4-130
CAS:AC-4-130 is a direct STAT5 SH2 domain inhibitor, inducing cell cycle arrest and apoptosis in leukemia cells, acute myeloid leukemia (AML).Fórmula:C37H36ClF5N2O5SPureza:99.93%Cor e Forma:SolidPeso molecular:751.2Ref: TM-T35429
1mgA consultar5mgA consultar10mgA consultar1mL*10mM (DMSO)A consultar25mg557,00€50mg898,00€100mg1.674,00€Prosultiamine
CAS:Prosultiamine is commonly used for treatment of beriberi, nutritional disorders caused by lack of vitamin B1, etc.Fórmula:C15H24N4O2S2Pureza:98%Cor e Forma:White Crystalline Or Crystalline PowderPeso molecular:356.51CPTH6 hydrobromide
CAS:CPTH6, a thiazole derivative, selectively inhibits the lysine acetyltransferase activity of Gcn5 and pCAF without affecting p300 or CBP. It effectively blocks the acetylation of H3/H4 histones and α-tubulin in various leukemia cell lines, leading to reduced cell viability by arresting the cell cycle in the G0/G1 phase and inducing apoptosis. Additionally, CPTH6 disrupts autophagy across several tumor cell lines, primarily by interfering with ATG7-mediated autophagosomal membrane elongation.Fórmula:C15H16ClN3SHBrCor e Forma:SolidPeso molecular:386.7p-Decylaminophenol
CAS:p-Decylaminophenol is a melanogenesis inhibitor.Fórmula:C16H27NOPureza:98%Cor e Forma:SolidPeso molecular:249.39Ionomycin calcium
CAS:Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.
Fórmula:C41H70CaO9Pureza:98% - 98.11%Cor e Forma:SolidPeso molecular:747.07EGFR-IN-117
CAS:EGFR-IN-117 (Compound 8h) exhibits inhibitory activity against EGFR mutations, specifically targeting the tumor environment and inducing apoptosis in cancer cells. This compound effectively inhibits the proliferation of H1975, PC-9, and mutant EGFR cells including BaF3-EGFRL858R/T790M/C797S and BaF3–C797S/Del19/T790M, with IC50 values of 13 nM, 19 nM, 1.2 nM, and 1.3 nM respectively. Additionally, EGFR-IN-117 demonstrates anti-tumor activity in mouse models.Fórmula:C25H30BrN7O2SCor e Forma:SolidPeso molecular:572.52Xevinapant hydrochloride
CAS:Xevinapant hydrochloride (AT-406 HCl) , an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide.Fórmula:C32H44ClN5O4Pureza:98%Cor e Forma:SolidPeso molecular:598.19GZD856 formic
CAS:GZD856 formic inhibits PDGFRα/β (IC50: 68.6, 136.6 nM) & Bcr-Abl (IC50: 19.9, 15.4 nM), with antitumor properties.Fórmula:C30H29F3N6O3Cor e Forma:SolidPeso molecular:578.58Talaporfin sodium
CAS:Talaporfin is a photosensitizer used in photodynamic therapy.Fórmula:C38H41N5NaO9Pureza:98%Cor e Forma:SolidPeso molecular:734.762Desethylamiodarone
CAS:Diethylamiodarone is the main metabolite of amiodarone in vivo.Fórmula:C23H25I2NO3Pureza:98%Cor e Forma:SolidPeso molecular:617.264-(6-Bromo-2-benzothiazolyl)benzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET tracer and can be used in the diagnosis of neurological diseases.Fórmula:C13H9BrN2SPureza:98%Cor e Forma:SolidPeso molecular:305.19IA-14069
CAS:IA-14069 is a TNF-a inhibitor with anti-inflammatory activity and pro-inflammatory cytokine production, and is used in the study of colon cancer.Fórmula:C20H15ClF2O4Cor e Forma:SoildPeso molecular:392.78Diquafosol Free Base
CAS:Diquafosol Free Base is a purinoceptor P2Y(2) receptor agonist.Fórmula:C18H26N4O23P4Cor e Forma:SolidPeso molecular:790.31Esmolol hydrochloride
CAS:Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension.Fórmula:C16H25NO4·HClPureza:98.72% - 99.48%Cor e Forma:White SolidPeso molecular:331.15Kaolin
CAS:Kaolin (Bolus alba) is a clay dominated by minerals of the kaolinite family. Kaolin increased the sensitivity of this method for monitoring hemophilia therapy.Fórmula:Al2H8O9Si2Pureza:98%Cor e Forma:White Or Yellowish-White Earhty Mass Or White Powder; Unctuous When Moist (Al2O3(Sio2)2(H2O)2) A Hydrous Aluminosilicate Kaolinite Has Mp 740-1785°C And Density 2 65Peso molecular:262.188Quinacrine methanesulfonate
CAS:Quinacrine methanesulfonate is a bioactive chemical.Fórmula:C25H38ClN3O7S2Cor e Forma:SolidPeso molecular:592.17Dalbinol
CAS:Dalbinol is a useful organic compound for research related to life sciences. The catalog number is T124857 and the CAS number is 41993-79-7.Fórmula:C23H22O8Cor e Forma:SolidPeso molecular:426.421Zibotentan
CAS:Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.Fórmula:C19H16N6O4SPureza:97.00% - 97.02%Cor e Forma:SolidPeso molecular:424.43EGFR-IN-109
CAS:EGFR-IN-109 (compound 4), an EGFR inhibitor, displays IC 50 values of 25.8 nM for EGFR WT and 182.3 nM for EGFR T790M. This compound halts the growth of cancer cells at the G2/M phase and triggers both early and late apoptosis. It is applicable in cancer research [1].Fórmula:C12H16N4OSCor e Forma:SolidPeso molecular:264.35SM1044
CAS:SM1044 is a dimer of dihydroartemisinin (DHA). It activates caspase, inducing apoptosis in RL95-2 and KLE cells. SM1044 inhibits the proliferation of cancer cells RL95-2, KLE, HEC-50, HEC-1-A, HEC-1-B, and AN3CA, with an IC50 of less than 3.6 μM. Additionally, SM1044 suppresses tumor growth in RL95-2 xenograft mouse models.Fórmula:C34H55NO10Cor e Forma:SolidPeso molecular:637.80
