Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(116 produtos)
- PDK(9 produtos)
- PERK(24 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(65 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6114 produtos de "Apoptose"
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XMD15-44
CAS:XMD15-44, a RET kinase inhibitor, demonstrates potent growth-inhibitory effects on RAT1 cells transformed by RET/C634R and RET/M918T, with IC50 values of 11.5 nM and 8.3 nM, respectively. It effectively inhibits RET kinase activity and signaling in human thyroid cancer cell lines harboring oncogenic RET alleles, thereby reducing cell proliferation.Fórmula:C29H29F3N4OCor e Forma:SolidPeso molecular:506.56ORY-1001 free base
CAS:ORY-1001: potent KDM1A inhibitor (IC50 <20nM), selective, affects THP-1 cell gene regulation and apoptosis, hinders MV(4;11) cell growth (EC50 <1nM).Fórmula:C15H22N2Pureza:98%Cor e Forma:SolidPeso molecular:230.35PBOX-15
CAS:PBOX-15 induces apoptosis, regulates death receptors, enhances TRAIL effects, and inhibits T cell migration in myeloma cells.Fórmula:C28H19NO3Cor e Forma:SolidPeso molecular:417.46C1A
CAS:C1A is an inhibitor of HDAC6 which modulates downstream autophagy substrates and leads to growth inhibition of a diverse set of cancer cell lines.Fórmula:C22H25Cl2N3O4SCor e Forma:SolidPeso molecular:498.42F5446
CAS:F5446 is a selective small molecule SUV39H1 methyltransferase inhibitor, promotes apoptosis in colorectal cancer cells by inhibiting the deposition of H3K9me3.Fórmula:C26H17ClN2O8SPureza:98.56%Cor e Forma:SolidPeso molecular:552.94YLT-11
YLT-11: Oral PLK4 inhibitor, Kd 5.2 nM; less effective on PLK1/2/3; inhibits cancer cell growth and induces G2/M arrest and apoptosis.Fórmula:C24H24N6OCor e Forma:SolidPeso molecular:412.49SPRC
CAS:"SPRC, a synthetic antioxidant, boosts H2S production, activates STAT3, and guards against doxorubicin heart damage."Fórmula:C6H9NO2SPureza:98%Cor e Forma:SolidPeso molecular:159.21IMM-02
CAS:IMM-02 is a DID-DAD binding inhibitor.Fórmula:C13H17F2N3OSPureza:98%Cor e Forma:SolidPeso molecular:301.36PIK-C98
CAS:PIK-C98 is an inhibitor of PI3K that acts by displaying potent preclinical activity against multiple myeloma.Fórmula:C16H10Cl2N2OSPureza:98%Cor e Forma:SolidPeso molecular:349.23Thienopyridone
CAS:Thienopyridone: potent, selective PRL phosphatase inhibitor, IC50s: 173/277/128 nM for PRL-1/2/3, induces apoptosis, anticancer.Fórmula:C13H10N2OSPureza:98%Cor e Forma:SolidPeso molecular:242.3E64FC26
CAS:E64FC26 is a PDI family pan-inhibitor with antitumor activity that inhibits PDIA1 and PDIA6 and can be used to study multiple myeloma and pancreatic cancer.Fórmula:C19H23F3O2Pureza:98.1% - 98.1%Cor e Forma:SolidPeso molecular:340.38KS106
CAS:KS106 inhibits ALDH (1A1: 334 nM, 2: 2137 nM, 3A1: 360 nM), has anti-cancer properties, raises ROS, and promotes aldehyde build-up.Fórmula:C18H15BrF3N3O2SPureza:99.31%Cor e Forma:SolidPeso molecular:474.3Pim-1 kinase inhibitor 1
CAS:Pim-1 kinase inhibitor 1, IC50 0.11 μM, combats various cancers by inducing apoptosis.Fórmula:C19H13N3O3Cor e Forma:SolidPeso molecular:331.32Trehalose 6-behenate
CAS:Trehalose 6-behenate is a Th1/Th17 skewing vaccine adjuvant.Fórmula:C34H64O12Pureza:98%Cor e Forma:SolidPeso molecular:664.86Necrostatin-7
CAS:Necrostatin-7 (Necrostatin 7) is a necrotic apoptosis inhibitor with cardioprotective effects that inhibits RANK-NFATc1 signaling.Fórmula:C16H10FN5OS2Pureza:98.71%Cor e Forma:SolidPeso molecular:371.41EGFR-IN-52
CAS:EGFR-IN-52, a potent EGFR inhibitor, has IC50s: 0.358 μM (wild-type), 86.02 μM (L858R-TK), 432.67 μM (T790M-TK); induces cancer cell apoptosis.Fórmula:C19H18N4O3SCor e Forma:SolidPeso molecular:382.44Mitochonic Acid 35
CAS:Mitochonic Acid 35 is a dual TNF-α and TGF-β1 inhibitor that acts by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation.Fórmula:C19H19NO5Pureza:98%Cor e Forma:SolidPeso molecular:341.36NHI-2
CAS:NHI-2 is an LDHA inhibitor (IC50 14.7 µM) that blocks glycolysis, induces apoptosis and cell cycle arrest, and suppresses tumor growth in melanoma models.Fórmula:C17H12F3NO3Pureza:99.981%Cor e Forma:SolidPeso molecular:335.28Anticancer agent 67
CAS:Anticancer agent 67 is a ciprofloxacin analogue, an anticancer agent that induces apoptosis and increases sub-G1 cell populations in MCF-7 cells.Fórmula:C26H24F2N6O2S2Cor e Forma:SolidPeso molecular:554.63Quinidine Monosulfate
CAS:Quinidine Monosulfate: an oral antiarrhythmic, CYP450db inhibitor, K+ blocker (IC50 19.9 μM), used in malaria research.Fórmula:C40H50N4O8SCor e Forma:SolidPeso molecular:746.92
