Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(5 produtos)
- Caspase(151 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(105 produtos)
- PDK(9 produtos)
- PERK(26 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(58 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6043 produtos de "Apoptose"
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Ataquimast
CAS:Ataquimast is used in curing advanced receptor-positive breast cancer.Fórmula:C11H14ClN3OPureza:99.92%Cor e Forma:SolidPeso molecular:239.7Ref: TM-T30190
1mg64,00€5mg129,00€10mg188,00€25mg299,00€50mg427,00€100mg575,00€200mg750,00€1mL*10mM (DMSO)116,00€CUR61414
CAS:CUR61414 is a cell-permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM) and selectively binds to smoothened (Ki = 44 nM).Fórmula:C31H42N4O5Pureza:97.34% - 98%Cor e Forma:SolidPeso molecular:550.69Ref: TM-T15019
1mg52,00€2mg74,00€5mg110,00€10mg172,00€25mg344,00€50mg518,00€100mg780,00€200mg1.026,00€1mL*10mM (DMSO)123,00€NHWD-870
CAS:NHWD-870 selectively inhibits BET bromodomains BRD2-4, BRDT; potent anti-cancer effect by inducing apoptosis, halting cell growth.Fórmula:C29H29N7OPureza:98%Cor e Forma:SolidPeso molecular:491.59Anticancer agent 127
CAS:Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM,Fórmula:C26H37FN4O6SPureza:98%Cor e Forma:SolidPeso molecular:552.66Antitumor agent-60
CAS:Antitumor agent-60 inhibits growth by targeting RAS-RAF, binding CRAF (Kd: 721.3 nM), boosting p53/ROS, causing apoptosis, and arresting G2/M phase.Fórmula:C24H28O10SCor e Forma:SolidPeso molecular:508.54Thaspine acetate
CAS:Thaspine: inhibits topoisomerase IB, reduces VEGF, stops endothelial cell growth via PI3K/MAPK pathways.Fórmula:C22H23NO8Cor e Forma:SolidPeso molecular:429.425Anticancer agent 118
CAS:Anticancer Agent 118, an N‑acylated ciprofloxacin derivative, exhibits antibacterial efficacy against Gram-positive strains and antiproliferative effects onFórmula:C19H19ClFN3O4Cor e Forma:SolidPeso molecular:407.82MK-2206 free base
CAS:MK-2206 free base is an allosteric Akt inhibitor that is both potent and selective, administered orally, exhibiting IC50 values of 8, 12, and 65 nM for Akt1,Fórmula:C25H21N5OPureza:98%Cor e Forma:SolidPeso molecular:407.47RIPK-IN-4
CAS:RIPK-IN-4 is an effective and selective inhibitor of RIPK2. It also has excellent oral bioavailability (IC50: 3 nM).Fórmula:C18H21FN4O3SPureza:98%Cor e Forma:SolidPeso molecular:392.45Eeyarestatin I
CAS:Eeyarestatin I blocks ER protein degradation, hinders p97/atx3 processes, and induces anticancer proteins.Fórmula:C27H25Cl2N7O7Pureza:98% - 98.99%Cor e Forma:SolidPeso molecular:630.44RIP2 kinase inhibitor 1
CAS:Potent RIP2 kinase inhibitor with 0.03 μM IC50, selective for autoimmune disease treatment.Fórmula:C17H17N5O2SPureza:98%Cor e Forma:SolidPeso molecular:355.41AGN 192870
CAS:AGN 192870 is a potent retinoic acid receptor (RAR) antagonist.AGN 192870 can be used to study cell growth arrest, differentiation and apoptosis.Fórmula:C27H22O2Pureza:99.22%Cor e Forma:SolidPeso molecular:378.46Lacutoclax
CAS:Lacutoclax (LP-108) is an orally active and selective Bcl-2 inhibitor with antitumor activity both in vivo and ex vivo，lymphoma and leukemia.Fórmula:C48H55ClN8O7SCor e Forma:SolidPeso molecular:923.52RUNX-IN-2
CAS:RUNX-IN-2 (Compound Conjugate 3) covalently attaches to RUNX-binding sequences, preventing RUNX proteins from associating with their targets, thereby inhibitingFórmula:C71H88Cl2N24O11Pureza:98%Cor e Forma:SolidPeso molecular:1524.52MP7
CAS:MP7 (PDK1 inhibitor) is a inhibitor of phosphoinositide-dependent kinase-1 (PDK1).Fórmula:C28H22F2N4O4Pureza:99.89%Cor e Forma:SolidPeso molecular:516.5c-Met-IN-10
CAS:c-Met-IN-10: potent kinase inhibitor (IC50=16 nM), halts cancer cell activity/movement, induces apoptosis, for anticancer research.Fórmula:C26H21FN6O5Cor e Forma:SolidPeso molecular:516.48iMAC2 hydrochloride
CAS:iMAC2 hydrochloride, a potent inhibitor of the mitochondrial apoptosis-induced channel (MAC), demonstrates an IC50 of 28 nM and an LD50 of 15000 nM. It exhibits an anti-apoptotic effect by blocking the release of cytochrome c [1].Fórmula:C19H22Br2Cl2FN3Cor e Forma:SolidPeso molecular:542.11Biguanidinium-porphyrin
CAS:Imidodicarbonimidic diamide hydrochloride, a phototoxic compound with anti-proliferative properties.Fórmula:C46H36ClN9Pureza:92.48% - 93.91%Cor e Forma:SoildPeso molecular:750.29Delmitide acetate
CAS:Delmitide acetate (RDP58) is an orally active d-isomer decapeptide that exhibits potent anti-inflammatory properties.Fórmula:C61H109N17O13Pureza:98%Cor e Forma:SolidPeso molecular:1288.62CHMFL-FLT3-122
CAS:CHMFL-FLT3-122 is a potent and orally available FLT3 kinase inhibitor used to treat FLT3-ITD positive acute myeloid leukemia.
Fórmula:C26H29N7O2Pureza:99.63%Cor e Forma:SolidPeso molecular:471.55
