Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(5 produtos)
- Caspase(151 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(105 produtos)
- PDK(9 produtos)
- PERK(26 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(58 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6043 produtos de "Apoptose"
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Bcl-2-IN-12
CAS:Bcl-2-IN-12 (Compound 1) is a potent Bcl-2 inhibitor with an IC50 value of 6 nM, utilized in cancer research [1].Fórmula:C47H41ClN4O6SCor e Forma:SolidPeso molecular:825.37RET-IN-25
CAS:RET-IN-25 (compound 6b) is an anticancer RET kinase inhibitor that demonstrates efficacy against medullary thyroid carcinoma (MTC), exhibiting half-maximalFórmula:C22H17N3O5SCor e Forma:SolidPeso molecular:435.45D359-0396
CAS:D359-0396 is an orally active NLRP3 inflammasome inhibitor that mitigates pyroptosis and reduces IL-1β release in macrophages by inhibiting the oligomerizationFórmula:C24H24N4O2Pureza:98%Cor e Forma:SolidPeso molecular:400.47AMRI-59
CAS:AMRI-59 is a potent inhibitor of PrxI with anti-tumor activity.Fórmula:C25H27N3O2Pureza:99.79%Cor e Forma:SolidPeso molecular:401.5Ref: TM-T26623
1mg115,00€5mg249,00€10mg368,00€25mg562,00€50mg787,00€100mg1.054,00€500mg2.118,00€1mL*10mM (DMSO)274,00€15-Deoxy-Δ12,14-prostaglandin A1
CAS:15-Deoxy-Δ12,14-Prostaglandin A1, a deoxyanalog of prostaglandins, inhibits NF-κB signaling and induces apoptosis. It also prevents TNF-α-induced upregulation of inflammatory endothelial cell adhesion molecules (CAM) and reduces monocyte arrest [1].Fórmula:C20H30O3Cor e Forma:SolidPeso molecular:318.457Anticancer agent 127
CAS:Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM,Fórmula:C26H37FN4O6SPureza:98%Cor e Forma:SolidPeso molecular:552.66RUNX-IN-2
CAS:RUNX-IN-2 (Compound Conjugate 3) covalently attaches to RUNX-binding sequences, preventing RUNX proteins from associating with their targets, thereby inhibitingFórmula:C71H88Cl2N24O11Pureza:98%Cor e Forma:SolidPeso molecular:1524.52ST1074
CAS:ST1074, a dual inhibitor of CerS2 and CerS4, promotes apoptosis and is applicable in cancer research [1].Fórmula:C20H36ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:373.96AGN194204
CAS:AGN194204 (IRX4204), an oral RXR agonist, inactive against RAR, has Kd 0.4-3.8 nM & EC50 0.08-0.8 nM, with anti-inflammatory and anticarcinogenic properties.Fórmula:C24H32O2Pureza:98%Cor e Forma:SolidPeso molecular:352.51Deoxynybomycin
CAS:Deoxynybomycin, a selective anti-tumor agent, inhibits topoisomerase I and induces apoptosis.Fórmula:C16H14N2O3Pureza:98%Cor e Forma:SolidPeso molecular:282.29ML 10
CAS:ML 10, a [18F] PET radiotracer, detects apoptosis-specific alterations in atherosclerotic plaques.Fórmula:C9H15FO4Cor e Forma:SolidPeso molecular:206.21BQZ-485
CAS:BQZ-485, a potent GDI2 inhibitor, interacts with Tyr245 to disrupt the native GDI2-Rab1A interaction.Fórmula:C32H39NO3Pureza:98%Cor e Forma:SolidPeso molecular:485.66JAB-2485
CAS:JAB-2485 is a highly potent and selective inhibitor of Aurora kinase A (AURKA), boasting an IC 50 of 0.33 nM, and demonstrates approximately 1700-fold selectivity for AURKA over AURKB. It induces cell cycle arrest and apoptosis, making it a valuable compound for cancer research [1].Fórmula:C25H28ClF2N5O2Peso molecular:503.97YS-363
CAS:YS-363 is a potent, selective, and orally active inhibitor of the epidermal growth factor receptor (EGFR), exhibiting half-maximal inhibitory concentrations (
Fórmula:C30H30N4O3Pureza:98%Cor e Forma:SolidPeso molecular:494.58M190S
CAS:M109S is a novel small molecule that shields cells from mitochondria-dependent apoptosis, demonstrating effectiveness both in vitro and in vivo.Fórmula:C21H21N5O2Pureza:98%Cor e Forma:SolidPeso molecular:375.42Antitumor agent-97
CAS:Antitumor agent-97 (compound 42), an anticancer agent, effectively inhibits proliferation and autophagy in MGC 803 cells, induces apoptosis, and enhances ROSFórmula:C24H34O3Pureza:98%Cor e Forma:SolidPeso molecular:370.52HDAC-IN-50
CAS:HDAC-IN-50, a potent FGFR/HDAC inhibitor (IC50: 0.18-13 nM), induces apoptosis, cell cycle arrest, and shows anti-tumor activity.Fórmula:C31H41N7O4Cor e Forma:SolidPeso molecular:575.7BRD4 Inhibitor-18
CAS:BRD4 Inhibitor-18: potent (IC50: 110 nM), impairs MV-4-11 cell growth, disrupts G0/G1 phase, and induces apoptosis.Fórmula:C26H26ClN3O3SCor e Forma:SolidPeso molecular:496.02Agerafenib hydrochloride
CAS:Agerafenib hydrochloride is a highly potent inhibitor of BRAFV600E (Kd: 14 nM).Fórmula:C24H23ClF3N5O5Pureza:98%Cor e Forma:SolidPeso molecular:553.92Bcl-2-IN-11
CAS:Bcl-2-IN-11 (compound 6) is a potent and selective inhibitor of Bcl-2 activity, exhibiting an IC50 of 0.9 nM, and demonstrates minimal inhibition against Bcl-xlFórmula:C45H49ClFN7O8SCor e Forma:SolidPeso molecular:902.43
