Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(114 produtos)
- CDK(545 produtos)
- Ciclo celular/Parada(5 produtos)
- Chk(48 produtos)
- DYRK(47 produtos)
- Dinamina(27 produtos)
- Ferroptose(226 produtos)
- HSP(179 produtos)
- Integrinas(249 produtos)
- Cinesina(87 produtos)
- LIM Quinase(20 produtos)
- Microtúbulo associado(274 produtos)
- PKC(124 produtos)
- PLK(25 produtos)
- ROCK(62 produtos)
- Rho(6 produtos)
- Wee1(14 produtos)
- c-Myc(76 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3859 produtos de "Ciclo celular/Ponto de verificação"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
TH1760
CAS:TH1760 inhibits NUDT15 (IC50=25nM); boosts 6-thioguanine efficacy in leukemia by raising 6-thio-(d)GTP.Fórmula:C20H18N4O5SPureza:97.31%Cor e Forma:SoildPeso molecular:426.45Sulfameter
CAS:Sulfameter (Sulfametoxydiazine) is a long-acting sulfonamide antibacterial agent used to treat urinary tract infections and leprosy.Fórmula:C11H12N4O3SPureza:99.46% - 99.90%Cor e Forma:Crystalline SolidPeso molecular:280.3Tegafur
CAS:Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity.Fórmula:C8H9FN2O3Pureza:99.16% - 99.89%Cor e Forma:White Crystalline PowderPeso molecular:200.17Upamostat
CAS:Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.Fórmula:C32H47N5O6SPureza:99.41%Cor e Forma:SolidPeso molecular:629.81Ref: TM-T13257
1mg64,00€2mg94,00€5mg145,00€10mg226,00€25mg379,00€50mg538,00€100mg730,00€1mL*10mM (DMSO)163,00€ATN-161 acetate
CAS:ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.Fórmula:C25H39N9O10SPureza:98.27%Cor e Forma:SoildPeso molecular:657.7Ref: TM-T10398L
1mg190,00€5mg471,00€10mg663,00€25mg1.036,00€50mg1.429,00€100mg1.830,00€200mg2.498,00€Abituzumab
CAS:Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.Pureza:>95%Cor e Forma:LiquidPeso molecular:144.58 kDaBT173
CAS:BT173 is a novel inhibitor of homeodomain interacting protein kinase 2 (HIPK2 ), attenuating renal fibrosis through suppression of the TGF-ß1/Smad3 pathway.Fórmula:C18H12BrN3O2Pureza:98.247%Cor e Forma:SolidPeso molecular:382.21MKC8866
CAS:MKC8866, a selective IRE1 RNase inhibitor with an IC50 of 0.29 μM, curbs breast and prostate cancer cell growth.Fórmula:C18H19NO7Pureza:99.28% - 99.854%Cor e Forma:SolidPeso molecular:361.35Ref: TM-T15594
1mg84,00€2mg109,00€5mg177,00€10mg250,00€25mg423,00€50mg557,00€100mg760,00€200mg1.018,00€1mL*10mM (DMSO)192,00€N-Dodecyl-β-D-maltoside
CAS:N-Dodecyl-β-D-maltoside (Lauryl Maltoside) has also been employed in applications such as in the purification and stabilization of RNA polymerase and theFórmula:C24H46O11Pureza:99.18% - >99.99%Cor e Forma:White PowderPeso molecular:510.62Tinengotinib
CAS:Tinengotinib is a multikinase inhibitor that targets a series of kinases , including Aurora kinases A/B, JAK1/2, FGFR1/2/3, VEGFRs, and many other kinases.Fórmula:C20H19ClN6OPureza:99.05%Cor e Forma:SolidPeso molecular:394.86Osalmid
CAS:Osalmid (Oxaphenamide) is a choleretic drug, inhibits ribonucleotide reductase activity by targeting ribonucleotide reductase small subunit M2 (RRM2).Fórmula:C13H11NO3Pureza:99.08% - 99.6%Cor e Forma:White CrystalPeso molecular:229.23Foscarnet sodium
CAS:Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis.Fórmula:CNa3O5PPureza:98.52%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:191.95Doxifluridine
CAS:Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity.Fórmula:C9H11FN2O5Pureza:99.47% - 99.86%Cor e Forma:White SolidPeso molecular:246.19Foralumab
CAS:Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.Pureza:96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:146.59 kDaGemifloxacin mesylate
CAS:Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventuallyFórmula:C19H24FN5O7SPureza:97.24% - ≥95%Cor e Forma:Beige SolidPeso molecular:485.49Teplizumab
CAS:Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.Pureza:SDS-PAGE:95.8%;SEC-HPLC:99.7%Cor e Forma:LiquidPeso molecular:145.79 kDaCarmofur
CAS:Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.Fórmula:C11H16FN3O3Pureza:98.53% - 99.98%Cor e Forma:SolidPeso molecular:257.26Orbofiban TFA
CAS:Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFórmula:C19H24F3N5O6Pureza:97.21% - 98.72%Cor e Forma:SolidPeso molecular:475.42Centrinone
CAS:Centrinone (LCR-263) (LCR-263) is a reversible inhibitor of polo-like kinase 4 (PLK4; Ki:0.16 nM).Fórmula:C26H25F2N7O6S2Pureza:98.76%Cor e Forma:SolidPeso molecular:633.65DNA2 inhibitor C5
CAS:DNA2 inhibitor C5 is a specific cancer sensitizer with an IC50 of 20 μM, targeting multiple DNA2 activities.Fórmula:C10H6N2O5Pureza:99.05%Cor e Forma:SolidPeso molecular:234.16Ref: TM-T15146
1mg57,00€2mg80,00€5mg113,00€10mg178,00€25mg409,00€50mg605,00€100mg860,00€500mg1.728,00€1mL*10mM (DMSO)112,00€RWJ 50271
CAS:RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Fórmula:C18H17F3N4O2SPureza:99.09%Cor e Forma:SolidPeso molecular:410.41Ref: TM-T12783
1mg120,00€5mg295,00€10mg447,00€25mg707,00€50mg964,00€100mg1.243,00€200mg1.693,00€1mL*10mM (DMSO)326,00€Ledoxantrone trihydrochloride
CAS:Ledoxantrone trihydrochloride is a Top II inhibitor with anticancer activity and is used in the study of digestive disorders and urologic disorders.Fórmula:C21H30Cl3N5OSPureza:98.13%Cor e Forma:SoildPeso molecular:506.92Arg-Gly-Asp-Ser acetate
Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.Fórmula:C17H31N7O10Pureza:98.14%Cor e Forma:SolidPeso molecular:493.47GRL0617
CAS:GRL0617 is a selective and competitive SARS-CoVPLpro and deubiquitinase noncovalent inhibitor(IC50 : 0.6 μM, Ki : 0.49 μM).Fórmula:C20H20N2OPureza:99.31%Cor e Forma:SolidPeso molecular:304.39Ref: TM-T11464
1mg34,00€5mg74,00€10mg105,00€25mg178,00€50mg313,00€100mg500,00€500mg1.063,00€1mL*10mM (DMSO)82,00€P 218
CAS:P 218 is a novel DHFR inhibitor with antimalarial activity and antifolate effects and can be used to study Buruli ulcer.Fórmula:C18H25ClN4O4Pureza:98.83%Cor e Forma:SoildPeso molecular:396.87Procarbazine hydrochloride
CAS:Procarbazine hydrochloride (NSC-77213 HCl) is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities.Fórmula:C12H19N3O·HClPureza:96.99% - ≥98%Cor e Forma:(Ntp 1992)Peso molecular:257.76Rifabutin
CAS:Rifabutin (LM-427), a semisynthetic ansamycin, blocks bacterial RNA synthesis by inhibiting RNA polymerase.Fórmula:C46H62N4O11Pureza:98.87% - 99.7%Cor e Forma:Red-Violet Crystalline PowderPeso molecular:847.00C527
CAS:C527 is a is a pan DUB enzyme inhibitor. Which has a high potency for the USP1/UAF1 complex (IC50=0.88 μM).Fórmula:C17H8FNO3Pureza:97.22%Cor e Forma:SolidPeso molecular:293.25Monalizumab
CAS:Monalizumab, a humanized antibody, enhances NK cell function by inhibiting NKG2A; used in HNSCC studies.Pureza:95% - >95.0% (SDS-PAGE); 100% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:147 kDaAbrilumab
CAS:Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Pureza:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:143.80 kDaEnrofloxacin
CAS:Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.
Fórmula:C19H22FN3O3Pureza:99.43% - >99.99%Cor e Forma:Pale Yellow CrystalsPeso molecular:359.39Rifaximin
CAS:Rifaximin: an oral semi-synthetic antibiotic from rifamycin SV; targets bacterial RNA polymerase to halt growth.Fórmula:C43H51N3O11Pureza:99.18% - 99.40%Cor e Forma:Red-Orange Crystalline PowderPeso molecular:785.88hSMG-1 inhibitor 11j
CAS:hSMG-1 inhibitor 11j: pyrimidine, IC50=0.11 nM, >455x selective vs. mTOR/PI3Kα/γ/CDK1/CDK2; cancer research use.
Fórmula:C27H28ClN7O3SPureza:99.22% - 99.65%Cor e Forma:SolidPeso molecular:566.07Levofloxacin hydrate
CAS:Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.Fórmula:C18H20FN3O4H2OPureza:98.26%Cor e Forma:Pale Yellow SolidPeso molecular:370.38Procaine
CAS:Procaine (Vitamin H3) is a slow-acting ester local anesthetic with a short effect, used for infiltration, nerve, and spinal blocks.
Fórmula:C13H20N2O2Pureza:99.57% - 99.73%Cor e Forma:Anhydrous Plates Tables From Ligroin Or Ether SolidPeso molecular:236.31ATN-161 trifluoroacetate salt
CAS:ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Fórmula:C25H36F3N9O10SPureza:98% - 99.98%Cor e Forma:SolidPeso molecular:711.67Hu7691 free base
CAS:Hu7691 free base is an Akt inhibitor that inhibits Akt1, Akt2 and Akt3 and induces differentiation of neuroblastoma cells.Fórmula:C22H21F3N4OPureza:98.89%Cor e Forma:SolidPeso molecular:414.423BMVC-8C3O
CAS:BMVC-8C3O is a DNA G-quadruplex (G4) ligand.Cost-effective and quality-assured.Fórmula:C42H53I3N4O3Pureza:99.72%Cor e Forma:SolidPeso molecular:1042.61Ref: TM-T13584
1mg101,00€5mg192,00€10mg285,00€25mg462,00€50mg623,00€100mg858,00€200mg1.153,00€1mL*10mM (DMSO)371,00€TK216
CAS:TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.Fórmula:C19H15Cl2NO3Pureza:97.22%Cor e Forma:SolidPeso molecular:376.23Trimethoprim
CAS:Trimethoprim (NSC-106568) inhibits dihydrofolate reductase, CYP2C8, and OCT2 - an antibacterial agent.Fórmula:C14H18N4O3Pureza:99.80% - 99.81%Cor e Forma:White To Yellowish PowderPeso molecular:290.32NMDI14
CAS:NMDI14 is an inhibitor of nonsense mediated RNA decay (NMD).Fórmula:C21H25N3O4SPureza:97.79% - 99.37%Cor e Forma:SolidPeso molecular:415.51Ref: TM-T12235
1mg35,00€5mg74,00€10mg119,00€25mg236,00€50mg356,00€100mg537,00€200mg762,00€1mL*10mM (DMSO)84,00€BAY-524
CAS:BAY-524 is an inhibitor of Bub1(IC50 = 450 nM.human Bub1 in the presence of 2 mM ATP).Fórmula:C24H24F2N6O3Pureza:98.68% - 99.57%Cor e Forma:SolidPeso molecular:482.48Ref: TM-T14505
1mg96,00€5mg177,00€10mg298,00€25mg482,00€50mg658,00€100mg892,00€1mL*10mM (DMSO)178,00€Pazufloxacin Mesylate
CAS:Pazufloxacin Mesylate (T-3762) is a fluoroquinolone antibiotic.Fórmula:C16H15FN2O4·CH4O3SPureza:99.88% - 99.93%Cor e Forma:Crystalline SolidPeso molecular:414.4Nedaplatin
CAS:Nedaplatin, a cisplatin derivative, induces tumor DNA damage (IC50: 94 μM) through platinum-DNA cross-links, causing apoptosis.Fórmula:C2H8N2O3PtPureza:99.88% - >99.99%Cor e Forma:Straw Yellow PowderPeso molecular:303.17GSK-3 inhibitor 4
CAS:Orally active GSK-3 inhibitor 4 targets GSK-3α/β, CDK2/5 (IC50: 0.45-0.68 μM) and may aid in Alzheimer's research by lowering Tau protein.Fórmula:C22H15F2N5OPureza:99.82%Cor e Forma:SoildPeso molecular:403.38Ref: TM-T77341
1mg315,00€5mg873,00€10mg1.080,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg3.537,00€Tenofovir diphosphate TEA
CAS:Tenofovir diphosphate TEA (TFV-DP TEA) is an ATP-competitive DNA polymerase inhibitor that inhibits HIV-1 reverse transcriptase that\has anti-HIV/HBV potential.Fórmula:C9H16N5O10P3·C6H15NPureza:93.45% - 98.51%Cor e Forma:SolidPeso molecular:548.36RG7800
CAS:RG7800 (RO6885247) has the potential for spinal muscular atrophy treatment. RG7800 is an SMN2 splicing modifier.Fórmula:C24H28N6OPureza:99.44%Cor e Forma:SolidPeso molecular:416.52Y-33075 dihydrochloride
CAS:Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).Fórmula:C16H18Cl2N4OPureza:98.88% - 99.89%Cor e Forma:SolidPeso molecular:353.25Ref: TM-T13384L
1mg34,00€5mg66,00€10mg102,00€25mg192,00€50mg341,00€100mg510,00€200mg732,00€1mL*10mM (DMSO)78,00€GSK-626616
CAS:GSK-626616: strong, oral DYRK3 inhibitor (IC50: 0.7 nM), affects DYRK family, may treat anemia.Fórmula:C18H10Cl2N4OSPureza:98.27%Cor e Forma:SolidPeso molecular:401.27BAY-2402234
CAS:BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.Fórmula:C21H18ClF5N4O4Pureza:98.9%Cor e Forma:SolidPeso molecular:520.84Ref: TM-T14501
1mg170,00€2mg234,00€5mg349,00€10mg537,00€25mg858,00€50mg1.161,00€100mg1.558,00€1mL*10mM (DMSO)401,00€Diaveridine
CAS:Diaveridine (AI3-23935) (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide.Fórmula:C13H16N4O2Pureza:99.10%Cor e Forma:White SolidPeso molecular:260.29Enoxacin hydrate
CAS:Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.Fórmula:C15H17FN4O3H2OPureza:99.50%Cor e Forma:SolidPeso molecular:347.34AZ1495
CAS:AZ1495: oral IRAK4 inhibitor (IC50: 5 nM), IRAK1 (23 nM), treats MYD88L265P DLBCL.Fórmula:C21H31N5O2Pureza:98.81%Cor e Forma:SolidPeso molecular:385.5Ref: TM-T14367
1mg93,00€5mg156,00€10mg245,00€25mg349,00€50mg494,00€100mg750,00€200mg1.009,00€1mL*10mM (DMSO)170,00€Ribociclib succinate
CAS:Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).Fórmula:C27H36N8O5Pureza:99.9%Cor e Forma:SolidPeso molecular:552.63Ref: TM-T15732
2mg34,00€5mg49,00€10mg70,00€25mg92,00€50mg109,00€100mg165,00€200mg258,00€500mg459,00€1mL*10mM (DMSO)60,00€JH-RE-06
CAS:JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.Fórmula:C20H16Cl3N3O4Pureza:99.29%Cor e Forma:SolidPeso molecular:468.72Ref: TM-T15611
1mg44,00€5mg93,00€10mg152,00€25mg334,00€50mg587,00€100mg1.044,00€1mL*10mM (DMSO)95,00€DHODH-IN-11
CAS:DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.Fórmula:C15H11N3O2Pureza:98.14%Cor e Forma:SolidPeso molecular:265.27AZ-Dyrk1B-33
CAS:AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.Fórmula:C19H16N4Pureza:99.91%Cor e Forma:SolidPeso molecular:300.36Ref: TM-T14364
1mg44,00€5mg92,00€10mg147,00€25mg289,00€50mg419,00€100mg583,00€200mg787,00€1mL*10mM (DMSO)100,00€Pyrimethamine
CAS:Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.Fórmula:C12H13ClN4Pureza:99.67%Cor e Forma:CrystalsPeso molecular:248.71Mps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Fórmula:C26H31N7O4SPureza:99.25%Cor e Forma:SolidPeso molecular:537.63Ref: TM-T16130
2mg34,00€5mg54,00€10mg87,00€25mg149,00€50mg255,00€100mg384,00€200mg538,00€1mL*10mM (DMSO)64,00€HBX 19818
CAS:HBX 19818 is a specific ubiquitin-specific protease 7 (USP7) inhibitor (IC50: 28.1 μM).Fórmula:C25H28ClN3OPureza:97.71%Cor e Forma:SolidPeso molecular:421.96Ref: TM-T15464
1mg35,00€5mg80,00€10mg111,00€25mg177,00€50mg253,00€100mg353,00€200mg502,00€1mL*10mM (DMSO)89,00€TAME hydrochloride
CAS:TAME hydrochloride (Tos-Arg-OMe HCl) is a kind od amino acid derivatives.Fórmula:C14H23ClN4O4SPureza:99.11% - 99.21%Cor e Forma:White Fine Crystalline PowderPeso molecular:378.87Netarsudil Dihydrochloride
CAS:Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) is an inhibitor of Rho-related protein kinase (ROCK) and norepinephrine transporter (NET) and is effective in reducing intraocular pressure (IOP).Cost-effective and quality-assured.Fórmula:C28H29Cl2N3O3Pureza:99.94% - 99.98%Cor e Forma:SolidPeso molecular:526.45GSK-1520489A
CAS:GSK-1520489A is an active PKMYT1 inhibitor.Fórmula:C21H23N5O3SPureza:99.85%Cor e Forma:SolidPeso molecular:425.5XPW1
CAS:XPW1 is a CDK9 inhibitor with antitumor activity, inhibits DNA repair procedures, and can be used for the research of clear cell renal cell carcinoma.Fórmula:C36H39ClFN7O2Pureza:98.08%Cor e Forma:SoildPeso molecular:656.19Cyclin K degrader 1
Cyclin K degrader 1 is a Cyclin K degrader.Cyclin K degrader 1 is a degrader converted from AT-7519.Cyclin K degrader 1 has weak degrading activity against Cyclin K but does not result in a sustained decrease in degradation affinity.Cyclin K degrader 1 is a degrader converted from AT-7519.Fórmula:C23H17Cl2N5O2Pureza:99.76%Cor e Forma:SolidPeso molecular:466.32Cibisatamab
CAS:Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.Pureza:SDS-PAGE:99.1%;SEC-HPLC:96.5%Cor e Forma:LiquidPeso molecular:191.1 kDaCirtuvivint
CAS:Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor that can be used to study arthritis.Fórmula:C24H25N7OPureza:99.95% - 99.96%Cor e Forma:SolidPeso molecular:427.5Butylparaben
CAS:Butylparaben (Butyl 4-hydroxybenzoate) is a standardized chemical allergen, increasing histamine release, and cell-mediated immunity.Fórmula:C11H14O3Pureza:98.15%Cor e Forma:Small Colorless Crystals Or Powder Tongue Aqueous Solutions Slightly Acidic To Litmus (Ntp 1992)Peso molecular:194.23LY 345899
CAS:LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for
Fórmula:C20H21N7O7Pureza:99.7%Cor e Forma:SolidPeso molecular:471.42HLM006474
CAS:HLM006474 is a pan inhibitor of E2F. This inhibits E2F4 DNA-binding (IC50: 29.8 μM in A375 cells).Fórmula:C25H25N3O2Pureza:99.04% - 99.20%Cor e Forma:SolidPeso molecular:399.48TAO Kinase inhibitor 2
CAS:TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.
Fórmula:C25H24N2O3Pureza:98.58%Cor e Forma:SoildPeso molecular:400.47MYCi975
CAS:MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.Fórmula:C25H16Cl2F6N2O2Pureza:99.3% - 99.82%Cor e Forma:SolidPeso molecular:561.3Otelixizumab
CAS:Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.Pureza:>95%Cor e Forma:LiquidLerociclib dihydrochloride
CAS:Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/Fórmula:C26H36Cl2N8OPureza:97.4%Cor e Forma:SolidPeso molecular:547.52TAK-901
CAS:TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among othersFórmula:C28H32N4O3SPureza:99.02% - 99.59%Cor e Forma:SolidPeso molecular:504.64Ref: TM-T2709
1mg35,00€5mg70,00€10mg104,00€25mg202,00€50mg329,00€100mg525,00€200mg748,00€1mL*10mM (DMSO)79,00€Trilaciclib hydrochloride
CAS:Trilaciclib hydrochloride (G1T28 hydrochloride) is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).Fórmula:C24H32Cl2N8OPureza:99.69% - 99.89%Cor e Forma:SolidPeso molecular:519.47Hycanthone
CAS:Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.Fórmula:C20H24N2O2SPureza:98.78%Cor e Forma:Yellow-Orange Powder (Ntp 1992)Peso molecular:356.48NU6140
CAS:NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).Fórmula:C23H30N6O2Pureza:98.33%Cor e Forma:SolidPeso molecular:422.52Ref: TM-T16359
2mg39,00€5mg60,00€10mg92,00€25mg177,00€50mg285,00€100mg414,00€200mg580,00€1mL*10mM (DMSO)67,00€Rifapentine
CAS:Rifapentine (Rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.Fórmula:C47H64N4O12Pureza:95.74% - ≥98%Cor e Forma:SolidPeso molecular:877.03Vitamin D2
CAS:Ergocaliferol (Vitamin D2), derived from ergosterol by UV, inhibits bladder tumor promotion and leukemia, and blocks DNA Polymerase.Fórmula:C28H44OPureza:98.73% - 99.89%Cor e Forma:Prisms From Acetone 1998)Peso molecular:396.65R-10015
CAS:R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.Fórmula:C20H19ClN6O2Pureza:98.68%Cor e Forma:SolidPeso molecular:410.86Ref: TM-T12609
1mg50,00€5mg112,00€10mg170,00€25mg280,00€50mg371,00€100mg525,00€200mg712,00€1mL*10mM (DMSO)124,00€SIBA
CAS:SIBA, a synthetic SAH analog, inhibits SAM-dependent transmethylation and blocks HSV-1 replication.Fórmula:C14H21N5O3SPureza:99.48%Cor e Forma:SolidPeso molecular:339.41Ref: TM-T12908
1mg52,00€5mg94,00€10mg117,00€25mg220,00€50mg329,00€100mg469,00€200mg652,00€1mL*10mM (DMSO)104,00€Abciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Pureza:SDS-PAGE:95.2%;SEC-HPLC:95.9%Cor e Forma:LiquidPeso molecular:95.18 kDaPaprotrain
CAS:Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Fórmula:C16H11N3Pureza:99.91%Cor e Forma:SolidPeso molecular:245.28Ref: TM-T12359
5mg46,00€10mg58,00€25mg92,00€50mg160,00€100mg236,00€200mg353,00€500mg580,00€1mL*10mM (DMSO)49,00€SU056
CAS:SU056 is a YB-1 inhibitor that induces cell-cycle arrest, apoptosis, and inhibits ovarian cancer cell migration.
Fórmula:C20H16FNO5Pureza:99.89%Cor e Forma:SoildPeso molecular:369.34DI-87
CAS:DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.Fórmula:C23H30N6O3S2Pureza:99.76%Cor e Forma:SolidPeso molecular:502.65MALAT1-IN-1
CAS:MALAT1-IN-1 is an effective dose-dependent Malat1 inhibitor, not altering Neat1 expression.Fórmula:C19H21N3O2Pureza:99.58%Cor e Forma:SolidPeso molecular:323.39Ref: TM-T16007
5mg39,00€10mg63,00€25mg120,00€50mg224,00€100mg432,00€200mg623,00€1mL*10mM (DMSO)44,00€Metarrestin
CAS:Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.
Fórmula:C31H30N4OPureza:99.45%Cor e Forma:SolidPeso molecular:474.6Ref: TM-T12006
1mg40,00€2mg52,00€5mg88,00€10mg144,00€25mg298,00€50mg512,00€100mg740,00€500mg1.539,00€Nadifloxacin
CAS:Nadifloxacin (OPC7251) has been used in trials studying the treatment of Acne Vulgaris.Fórmula:C19H21FN2O4Pureza:99.03% - 99.7%Cor e Forma:Off-White Crystalline SolidPeso molecular:360.38Pefloxacin Mesylate Dihydrate
CAS:Pefloxacin Mesylate Dihydrate (1589 RB) , an antibacterial agent, restrains bacterial DNA replication by inhibiting DNA gyrase (topoisomerase).Fórmula:C17H20FN3O3·CH4O3S·2H2OPureza:99.79%Cor e Forma:SolidPeso molecular:465.49Ceftriaxone sodium hydrate
CAS:Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.Fórmula:C18H16N8Na2O7S3·5H2OPureza:99.77% - 99.78%Cor e Forma:White Or Almost White Crystalline Powder OdorlessPeso molecular:661.6Ribavirin
CAS:Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.Fórmula:C8H12N4O5Pureza:99.09% - 99.83%Cor e Forma:Less Solid Colourless SolidPeso molecular:244.20PTBP1-RNA-binding inhibitor P6 TFA
PTBP1-RNA-binding inhibitor P6 TFA is a stapled peptide inhibitor of PTBP1, used to inhibit RNA alternative splicing events regulated by PTBP1.Cor e Forma:Odour SolidCa2+ channel agonist 1
CAS:Ca2+ channel agonist 1 activates N-type Ca2+ channels and inhibits Cdk2 (EC50: 14.23 μM/3.34 μM) for motor nerve issues.Fórmula:C19H26N6OPureza:97.71%Cor e Forma:SolidPeso molecular:354.45Ref: TM-T10659
1mg97,00€5mg188,00€10mg284,00€25mg452,00€50mg645,00€100mg867,00€200mg1.130,00€1mL*10mM (DMSO)217,00€CDK2-IN-4
CAS:CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.Fórmula:C23H18N6O2SPureza:97.24% - 99.10%Cor e Forma:SolidPeso molecular:442.49Ref: TM-T14916
1mg82,00€5mg192,00€10mg304,00€25mg522,00€50mg713,00€100mg1.018,00€1mL*10mM (DMSO)212,00€Cinoxacin
CAS:Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics.Fórmula:C12H10N2O5Pureza:99.62% - 99.98%Cor e Forma:SolidPeso molecular:262.22Famciclovir
CAS:Famciclovir (BRL 42810) inhibits Herpes virus DNA polymerase by mimicking nucleosides.Fórmula:C14H19N5O4Pureza:99.85% - 99.99%Cor e Forma:Off-White PowderPeso molecular:321.33MKC9989
CAS:MKC9989 is an inhibitor of Hydroxy aryl aldehydes (HAA). MKC9989 also inhibits IRE1α with an IC50 of 0.23 to 44 μM.Fórmula:C17H20O7Pureza:99.3%Cor e Forma:SolidPeso molecular:336.34Ref: TM-T12071
1mg51,00€5mg156,00€10mg226,00€25mg376,00€50mg543,00€100mg730,00€1mL*10mM (DMSO)140,00€BRD6989
CAS:BRD6989, a cortistatin A analog, inhibits CDK8/19, enhances IL-10, and binds CDK8 with a 200 nM IC50.Fórmula:C16H16N4Pureza:99.43%Cor e Forma:SolidPeso molecular:264.33Ref: TM-T14778
1mg34,00€5mg66,00€10mg92,00€25mg177,00€50mg268,00€100mg398,00€200mg575,00€1mL*10mM (DMSO)73,00€Procaine hydrochloride
CAS:Procaine HCl is a benzoic acid derivative used as a local anesthetic, blocking nerve impulses and sensation.Fórmula:C13H20N2O2·HClPureza:99.1% - 99.22%Cor e Forma:White Crystalline PowderPeso molecular:272.77
