Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(94 produtos)
- CDK(500 produtos)
- Ciclo celular/Parada(4 produtos)
- Chk(42 produtos)
- DYRK(48 produtos)
- Dinamina(23 produtos)
- Ferroptose(215 produtos)
- HSP(169 produtos)
- Integrinas(224 produtos)
- Cinesina(66 produtos)
- LIM Quinase(19 produtos)
- Microtúbulo associado(261 produtos)
- PKC(102 produtos)
- PLK(28 produtos)
- ROCK(70 produtos)
- Rho(2 produtos)
- Wee1(15 produtos)
- c-Myc(69 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"
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PHA-767491
CAS:<p>PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.</p>Fórmula:C12H11N3OPureza:99.49% - >99.99%Cor e Forma:SolidPeso molecular:213.24Sarecycline free base
CAS:<p>Sarecycline free base (P005672) is a tetracycline-derived, narrow-spectrum antibiotic.</p>Fórmula:C24H29N3O8Pureza:98%Cor e Forma:SolidPeso molecular:487.5Seliciclib
CAS:<p>Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E, also inhibits Cdk7, Cdk5 and Cdc2. Seliciclib has antitumor effect. Cost-effective, quality assurance.</p>Fórmula:C19H26N6OPureza:97.15% - 99.89%Cor e Forma:White To Off-White SolidPeso molecular:354.45InhA-IN-2
CAS:<p>N-[3-(Aminomethyl)phenyl]-5-chloro-3-methyl-benzo[b]thiophene-2-sulfonamide inhibits InhA without KatG activation.</p>Fórmula:C16H15ClN2O2S2Pureza:98.4%Cor e Forma:SolidPeso molecular:366.89Protein kinase inhibitor 6
CAS:<p>Protein kinase inhibitor 6 is a protein kinase inhibitor.</p>Fórmula:C13H9FN2SPureza:98.01%Cor e Forma:SolidPeso molecular:244.29R-IMPP
CAS:<p>R-IMPP is an inhibitor of PCSK9 translation.</p>Fórmula:C24H27N3O2Pureza:99.47% - 99.85%Cor e Forma:SolidPeso molecular:389.496-Mercaptopurine hydrate
CAS:<p>6-Mercaptopurine hydrate is a leukemia treatment; it blocks purine metabolism, affecting DNA synthesis.</p>Fórmula:C5H6N4OSPureza:97.54% - 99.14%Cor e Forma:Light Yellow Crystalline PowderPeso molecular:170.19Mogroside I E1
CAS:<p>Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.</p>Fórmula:C36H62O9Pureza:98.62% - 99.71%Cor e Forma:SolidPeso molecular:638.87TH5487
CAS:<p>TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)</p>Fórmula:C19H18BrIN4O2Pureza:98.38% - 98.73%Cor e Forma:SolidPeso molecular:541.18Ro3280
CAS:<p>Ro3280 (Ro5203280) is an effective, specific inhibitor of PLK1(IC50=3, Kd=0.09 nM).</p>Fórmula:C27H35F2N7O3Pureza:97.1% - >99.99%Cor e Forma:SolidPeso molecular:543.61360A
CAS:<p>360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).</p>Fórmula:C27H23N5O2Pureza:98.68%Cor e Forma:SolidPeso molecular:449.5LIMK-IN-22j
CAS:<p>LIMK-IN-22j (LIMK inhibitor 22j) is an effective and selective inhibitor of LIMK.</p>Fórmula:C20H21BrN8Pureza:99.165%Cor e Forma:SolidPeso molecular:453.34BI-847325
CAS:<p>BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.</p>Fórmula:C29H28N4O2Pureza:97.13% - 97.54%Cor e Forma:SolidPeso molecular:464.56BS194
CAS:<p>BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.</p>Fórmula:C20H27N5O3Pureza:99.85%Cor e Forma:SolidPeso molecular:385.46CWHM-12
CAS:<p>CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).</p>Fórmula:C26H32BrN5O6Pureza:98.05% - 99.83%Cor e Forma:SolidPeso molecular:590.47CRT0066854
CAS:<p>CRT-0066854 is a PKCι and PKCζ inhibitor. CRT0066854 was able to restore polarized morphogenesis in the dysplastic H-Ras spheroids.</p>Fórmula:C24H25N5SCor e Forma:SolidPeso molecular:415.55CCG-222740
CAS:<p>CCG-222740 is an inhibitor of Rho/MRTF pathway</p>Fórmula:C23H19ClF2N2O3Pureza:98.76%Cor e Forma:SolidPeso molecular:444.86Ganciclovir sodium
CAS:<p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>Fórmula:C9H13N5NaO4Pureza:99.93%Cor e Forma:SolidPeso molecular:278.22Aplidine
CAS:<p>Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM).</p>Fórmula:C57H87N7O15Pureza:99.86%Cor e Forma:SolidPeso molecular:1110.34Aurora kinase inhibitor-2
CAS:<p>Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).</p>Fórmula:C23H20N4O3Pureza:98.66%Cor e Forma:SolidPeso molecular:400.43Activated Protein C (390-404), human acetate
<p>Activated Protein C (390-404), human acetate (Activated Protein C ) inhibits APC anticoagulant activity.</p>Fórmula:C93H134N22O25Pureza:99.92%Cor e Forma:SolidPeso molecular:1960.19Clevudine
CAS:<p>Clevudine (Levovir) fights HBV, blocks viral DNA synthesis, and has a long half-life reducing relapse risk after treatment.</p>Fórmula:C10H13FN2O5Pureza:99.88% - 99.97%Cor e Forma:SolidPeso molecular:260.22CID755673
CAS:<p>CID755673 inhibits PKD (IC50: 182 nM), with selectivity over PLK1, AKT, CAMKIIα, CAK, PKC.</p>Fórmula:C12H11NO3Pureza:97.68% - 99.84%Cor e Forma:SolidPeso molecular:217.22MC180295
CAS:<p>MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.</p>Fórmula:C17H18N4O3SPureza:99.84%Cor e Forma:SolidPeso molecular:358.41Favipiravir
CAS:<p>Favipiravir is a potent and selective RNA-dependent RNA polymerase inhibitor for the treatment of influenza virus infections.Cost-effective and quality-assured.</p>Fórmula:C5H4FN3O2Pureza:97.32% - 99.90%Cor e Forma:SolidPeso molecular:157.1Cyclo(-RGDfK)
CAS:<p>Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.</p>Fórmula:C27H41N9O7Pureza:95.29% - >99.99%Cor e Forma:SolidPeso molecular:603.67AZ3146
CAS:<p>AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.</p>Fórmula:C24H32N6O3Pureza:97.84% - >99.99%Cor e Forma:SolidPeso molecular:452.55Metoprine
CAS:<p>Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.</p>Fórmula:C11H10Cl2N4Pureza:98.42%Cor e Forma:SolidPeso molecular:269.13CID44216842
CAS:<p>CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.</p>Fórmula:C22H20BrN3O3SPureza:99.66%Cor e Forma:SolidPeso molecular:486.38SNS-314 Mesylate
CAS:<p>SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.</p>Fórmula:C18H15ClN6OS2·CH4O3SPureza:99.44% - 99.92%Cor e Forma:SolidPeso molecular:527.04DHFR-IN-3
CAS:<p>DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.</p>Fórmula:C8H7BrN4Pureza:99.521% - 99.65%Cor e Forma:SolidPeso molecular:239.07NSAH
CAS:<p>NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-</p>Fórmula:C18H14N2O3Pureza:99.27%Cor e Forma:SolidPeso molecular:306.32M2N12
CAS:<p>M2N12 selectively inhibits Cdc25C (IC50=0.09μM) and has anti-tumor properties, affecting Cdc25A and B as well.</p>Fórmula:C20H16ClN5O2Pureza:98.01%Cor e Forma:SolidPeso molecular:393.83HAMNO
CAS:<p>HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).</p>Fórmula:C17H13NO2Pureza:99.96%Cor e Forma:SolidPeso molecular:263.29TH287
CAS:<p>TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.</p>Fórmula:C11H10Cl2N4Pureza:97.73% - 99%Cor e Forma:SolidPeso molecular:269.136-AZATHYMINE
CAS:<p>6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.</p>Fórmula:C4H5N3O2Pureza:99.47%Cor e Forma:SolidPeso molecular:127.13-Methylcytidine
CAS:<p>3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.</p>Fórmula:C10H15N3O5Pureza:99.52%Cor e Forma:SolidPeso molecular:257.24IMT1B
CAS:<p>IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.</p>Fórmula:C24H21ClFNO6Pureza:98.26% - 99.83%Cor e Forma:SolidPeso molecular:473.88Irigenin
CAS:<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Fórmula:C18H16O8Pureza:99.50% - 99.85%Cor e Forma:SolidPeso molecular:360.31(1E)-CFI-400437 dihydrochloride
CAS:<p>(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.</p>Fórmula:C29H30Cl2N6O2Pureza:97.08%Cor e Forma:SolidPeso molecular:565.5Ganciclovir hydrate
CAS:<p>Ganciclovir hydrate: oral anti-cytomegalovirus; inhibits HSV 1/2, CMV, adenoviruses, FHV-1; brain-penetrating.</p>Fórmula:C9H15N5O5Cor e Forma:SolidPeso molecular:273.249TH-257
CAS:<p>TH-257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2, IC50 of 84 nM and 39 nM).</p>Fórmula:C24H26N2O3SPureza:98.23%Cor e Forma:SolidPeso molecular:422.54SR18662
<p>SR18662, improved ML264 derivative, inhibits KLF5 at 4.4 nM IC50; curbs colorectal cancer cell growth and triggers apoptosis.</p>Fórmula:C16H19Cl2N3O4SPureza:98.97% - 99.2%Cor e Forma:SolidPeso molecular:420.31CRT0044876
CAS:<p>CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.</p>Fórmula:C9H6N2O4Pureza:98.27% - 98.98%Cor e Forma:Brown PowderPeso molecular:206.15EHop-016
CAS:<p>EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.</p>Fórmula:C25H30N6OPureza:98.99% - >99.99%Cor e Forma:SolidPeso molecular:430.555-Fluoroorotic acid
CAS:<p>5-Fluoroorotic acid is an inhibitor of thymidylate synthase.</p>Fórmula:C5H3FN2O4Pureza:99.7% - >99.99%Cor e Forma:White To Pale Yellow PowderPeso molecular:174.09RI-2
CAS:<p>RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.</p>Fórmula:C21H18Cl2N2O4Pureza:99.63% - 99.86%Cor e Forma:SolidPeso molecular:433.28Quarfloxin
CAS:<p>Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.</p>Fórmula:C35H33FN6O3Pureza:99.77%Cor e Forma:SolidPeso molecular:604.67AS2863619
CAS:<p>AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.</p>Fórmula:C16H14Cl2N8OPureza:>99.99%Cor e Forma:SolidPeso molecular:405.242'-Fluoro-2'-Deoxyadenosine
CAS:<p>2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).</p>Fórmula:C10H12FN5O3Pureza:99.95%Cor e Forma:SolidPeso molecular:269.23BRD9876
CAS:<p>BRD9876 is a selective inhibitor of MM1S growth.</p>Fórmula:C16H14N2Pureza:97.81%Cor e Forma:SolidPeso molecular:234.3Ro5-3335
CAS:<p>Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins.</p>Fórmula:C13H10ClN3OPureza:99.42% - 99.87%Cor e Forma:SolidPeso molecular:259.69XL228
CAS:<p>XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).</p>Fórmula:C22H31N9OPureza:99.07%Cor e Forma:SolidPeso molecular:437.54Tozasertib
CAS:<p>Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).</p>Fórmula:C23H28N8OSPureza:99.99%Cor e Forma:SolidPeso molecular:464.59APY29
CAS:<p>APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.</p>Fórmula:C17H16N8Pureza:96.51% - 98.46%Cor e Forma:SolidPeso molecular:332.36SAR-020106
CAS:<p>SAR-020106 is a potent, ATP-competitive, and selective CHK1 inhibitor with an IC50 of 13.3 nmol/L on the isolated human enzyme.</p>Fórmula:C19H19ClN6OPureza:97.78%Cor e Forma:SolidPeso molecular:382.85CID-797718
CAS:<p>CID-797718 is a protein kinase D1 (PKD1) inhibitor.</p>Fórmula:C12H11NO3Pureza:98.91% - 99.21%Cor e Forma:SolidPeso molecular:217.22Tipiracil hydrochloride
CAS:<p>Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI).</p>Fórmula:C9H12Cl2N4O2Pureza:98.13% - ≥95%Cor e Forma:SolidPeso molecular:279.12Lurbinectedin
CAS:<p>Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.</p>Fórmula:C41H44N4O10SPureza:98.11%Cor e Forma:SolidPeso molecular:784.87THZ2
CAS:<p>THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC).</p>Fórmula:C31H28ClN7O2Pureza:98.28%Cor e Forma:SolidPeso molecular:566.05Voruciclib
CAS:<p>Voruciclib: oral, selective CDK inhibitor (Ki: 0.626-9.1 nM), reduces MCL-1, targets CDK9 in diffuse large B-cell lymphoma.</p>Fórmula:C22H19ClF3NO5Pureza:99.89%Cor e Forma:SolidPeso molecular:469.84Pyrintegrin
CAS:<p>Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.</p>Fórmula:C23H25N5O3SPureza:99.19%Cor e Forma:SolidPeso molecular:451.54GSK-923295
CAS:<p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>Fórmula:C32H38ClN5O4Pureza:96.22% - 98.02%Cor e Forma:SolidPeso molecular:592.13P18IN011
CAS:<p>P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).</p>Fórmula:C15H12N2O5SPureza:97.63%Cor e Forma:SolidPeso molecular:332.3310074-A4
CAS:<p>10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from</p>Fórmula:C18H14Cl2N2O3SPureza:99.06%Cor e Forma:SolidPeso molecular:409.29Madrasin
CAS:<p>Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.</p>Fórmula:C16H17N5O2Pureza:99.06% - 99.61%Cor e Forma:SolidPeso molecular:311.34BCH001
CAS:<p>BCH001 is a specific small-molecule inhibitor of PAPD5.</p>Fórmula:C20H15F3N2O5Pureza:99.06%Cor e Forma:SolidPeso molecular:420.34Trimethoprim sulfate
CAS:<p>Trimethoprim sulfate, a dihydrofolate reductase inhibitor, treats bacterial infections and sometimes malaria; may depress hematopoiesis.</p>Fórmula:C28H38N8O10SCor e Forma:SolidPeso molecular:678.72Dimethylenastron
CAS:<p>Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.</p>Fórmula:C16H18N2O2SPureza:98.07%Cor e Forma:SolidPeso molecular:302.39SCH900776 (S-isomer)
CAS:<p>SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).</p>Fórmula:C15H18BrN7Pureza:99.88%Cor e Forma:SolidPeso molecular:376.25THZ531
CAS:<p>THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM).</p>Fórmula:C30H32ClN7O2Pureza:97.17% - 99.86%Cor e Forma:SolidPeso molecular:558.07Senexin B
CAS:<p>Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of 140 nM and 80 nM).</p>Fórmula:C27H26N6OPureza:99.67%Cor e Forma:SolidPeso molecular:450.53RK33
CAS:<p>"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."</p>Fórmula:C23H20N6O3Pureza:99.04% - 99.72%Cor e Forma:SolidPeso molecular:428.44WNK463
CAS:<p>WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).</p>Fórmula:C21H24F3N7O2Pureza:>99.99% - ≥95%Cor e Forma:SolidPeso molecular:463.46N2-Methylguanosine
CAS:<p>N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA's</p>Fórmula:C11H15N5O5Pureza:97.77%Cor e Forma:SolidPeso molecular:297.27BIO-1211
CAS:<p>BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).</p>Fórmula:C36H48N6O9Pureza:99.33%Cor e Forma:SolidPeso molecular:708.8Levofloxacin hydrochloride
CAS:<p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Fórmula:C18H21ClFN3O4Pureza:99.78% - 99.98%Cor e Forma:SolidPeso molecular:397.8dGTP
CAS:<p>dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and</p>Fórmula:C10H16N5O13P3Pureza:99.64%Cor e Forma:SolidPeso molecular:507.18Triazavirin
CAS:<p>Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.</p>Fórmula:C5H7N6NaO5SPureza:99.55%Cor e Forma:SolidPeso molecular:286.2T-5224
CAS:<p>T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription</p>Fórmula:C29H27NO8Pureza:97.88% - 99.29%Cor e Forma:SolidPeso molecular:517.53KIRA6
CAS:<p>KIRA6 is an effective inhibitor of IRE1α RNase kinase (IC50: 0.6 μM). It can trigger an apoptotic response.</p>Fórmula:C28H25F3N6OPureza:97.91%Cor e Forma:SolidPeso molecular:518.53PRT4165
CAS:<p>PRT4165 (NSC600157) is a potent PRC1-mediated H2A ubiquitylation inhibitor.</p>Fórmula:C15H9NO2Pureza:98.91% - 99.6%Cor e Forma:SolidPeso molecular:235.24BS-181 hydrochloride
CAS:<p>BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.</p>Fórmula:C22H32N6·HClPureza:99.21%Cor e Forma:SolidPeso molecular:416.99CX-5461 dihydrochloride
<p>CX-5461 dihydrochloride: Oral Pol I inhibitor, HCT-116 (IC50: 142 nM), A375 (IC50: 113 nM), MIA PaCa-2 (IC50: 54 nM), weak on Pol II (IC50 ≥ 25 μM).</p>Fórmula:C27H29Cl2N7O2SCor e Forma:SolidPeso molecular:586.54Pyridostatin TFA
CAS:<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Cor e Forma:SolidPeso molecular:938.712,2'-Anhydrouridine
CAS:<p>2,2'-Anhydrouridine (2,2'-Cyclouridine) is a research tool for antiviral and anticancer studies.</p>Fórmula:C9H10N2O5Pureza:98.45%Cor e Forma:SolidPeso molecular:226.19Leukadherin-1
CAS:<p>Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.</p>Fórmula:C22H15NO4S2Pureza:98.49% - 98.93%Cor e Forma:SolidPeso molecular:421.49GSK180736A
CAS:<p>GSK180736A: GRK2 inhibitor (IC50 0.77µM), >100x selectivity vs GRKs, weak at PKA (IC50 30µM), strong vs ROCK1 (IC50 100nM).</p>Fórmula:C19H16FN5O2Pureza:98.38% - 98.98%Cor e Forma:SolidPeso molecular:365.36Gadodiamide
CAS:<p>Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.</p>Fórmula:C16H26GdN5O8Pureza:99.86%Cor e Forma:SolidPeso molecular:573.66K858 (Racemic)
CAS:<p>K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.</p>Fórmula:C13H15N3O2SPureza:>99.99%Cor e Forma:SolidPeso molecular:277.345-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE
CAS:<p>5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE targets PLK1.</p>Fórmula:C8H13N3SPureza:99.03%Cor e Forma:SolidPeso molecular:183.27Folinic acid calcium hydrate
CAS:<p>Folinic acid (Leucovorin) calcium hydrate is a biofolic acid often used as a rescue agent with methotrexate (MTX) to reduce MTX-induced toxicity.</p>Fórmula:C20H23CaN7O8Cor e Forma:SolidPeso molecular:529.523Sovilnesib
CAS:<p>Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.</p>Fórmula:C26H34F2N6O4SPureza:99.57%Cor e Forma:SolidPeso molecular:564.65GJ103 sodium salt
CAS:<p>GJ103 sodium salt, a GJ072 analog, lowers surface tension, viscosity, and pH in aqueous solutions, aiding molecular movement.</p>Fórmula:C16H13N4NaO3SPureza:99.70% - 99.91%Cor e Forma:SolidPeso molecular:364.36TAK-960 dihydrochloride
<p>TAK-960 dihydrochloride: oral PLK1 inhibitor, IC50 0.8 nM; also Hinders PLK2 and PLK3 (IC50s 16.9/50.2 nM); curbs cancer cell growth.</p>Fórmula:C27H36Cl2F3N7O3Cor e Forma:SolidPeso molecular:634.52Spermine tetrahydrochloride
CAS:<p>Spermine tetrahydrochloride, a polyamine in all eukaryotic cells, protects DNA from free radicals.</p>Fórmula:C10H26N4·4HClPureza:99.75% - 99.82%Cor e Forma:SolidPeso molecular:348.189-Ethylguanine
CAS:<p>9-Ethylguanine is a model nucleobase commonly used in the studies of DNA interactions with organometallic complexes.</p>Fórmula:C7H9N5OPureza:98.6%Cor e Forma:SolidPeso molecular:179.18RAD51-IN-1
CAS:<p>Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.</p>Fórmula:C22H16ClN3OPureza:99.95%Cor e Forma:SolidPeso molecular:373.83CBFβ Inhibitor
CAS:<p>CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.</p>Fórmula:C12H14N2OSPureza:96.50%Cor e Forma:SolidPeso molecular:234.32NITD-2
CAS:<p>NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.</p>Fórmula:C23H19N3O4SPureza:98.03% - 99.46%Cor e Forma:SolidPeso molecular:433.48
![5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT8912.webp&w=3840&q=75)
