Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(116 produtos)
- CDK(547 produtos)
- Ciclo celular/Parada(5 produtos)
- Chk(48 produtos)
- DYRK(46 produtos)
- Dinamina(27 produtos)
- Ferroptose(233 produtos)
- HSP(180 produtos)
- Integrinas(276 produtos)
- Cinesina(87 produtos)
- LIM Quinase(21 produtos)
- Microtúbulo associado(273 produtos)
- PKC(128 produtos)
- PLK(25 produtos)
- ROCK(61 produtos)
- Rho(6 produtos)
- Wee1(14 produtos)
- c-Myc(77 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3935 produtos de "Ciclo celular/Ponto de verificação"
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Levomefolate calcium
CAS:Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.Fórmula:C20H23CaN7O6Pureza:97.35%Cor e Forma:Off-White To Pale Yellow SolidPeso molecular:497.525'-Deoxy-5-fluorocytidine
CAS:5'-Deoxy-5-fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.Fórmula:C9H12FN3O4Pureza:99.67%Cor e Forma:White SolidPeso molecular:245.21LY3177833
CAS:LY3177833 is an Cdc7 kinase inhibitor (IC50 : 3.3 nM)Fórmula:C16H12FN5OPureza:99.87%Cor e Forma:SolidPeso molecular:309.3Ref: TM-T7810
1mg38,00€5mg80,00€1mL*10mM (DMSO)87,00€10mg109,00€25mg212,00€50mg318,00€100mg477,00€200mg677,00€AZD-7762
CAS:AZD-7762, an effective and specific inhibitor of Chk1（IC50=5 nM）, is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.Fórmula:C17H19FN4O2SPureza:98.96% - 99.19%Cor e Forma:SolidPeso molecular:362.42Ref: TM-T6093
1mg35,00€2mg50,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg90,00€25mg167,00€50mg265,00€100mg424,00€Fosifloxuridine nafalbenamide
CAS:Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.
Fórmula:C29H29FN3O9PPureza:95.87%Cor e Forma:SolidPeso molecular:613.53Barasertib-HQPA
CAS:Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.
Fórmula:C26H30FN7O3Pureza:98.43% - 99.29%Cor e Forma:SolidPeso molecular:507.56N6,N6-Dimethyladenosine
CAS:N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.Fórmula:C12H17N5O4Pureza:98.79%Cor e Forma:White PowderPeso molecular:295.29CBFβ Inhibitor
CAS:CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.Fórmula:C12H14N2OSPureza:96.50%Cor e Forma:SolidPeso molecular:234.32CW-069
CAS:CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.Fórmula:C23H21IN2O3Pureza:97.52% - 99.52%Cor e Forma:SolidPeso molecular:500.33Ref: TM-T6209
1mg40,00€5mg86,00€1mL*10mM (DMSO)94,00€10mg118,00€25mg205,00€50mg290,00€100mg409,00€500mg888,00€NITD-2
CAS:NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.Fórmula:C23H19N3O4SPureza:98.03% - 99.46%Cor e Forma:SolidPeso molecular:433.48Ref: TM-T8886
1mg74,00€5mg170,00€1mL*10mM (DMSO)188,00€10mg274,00€25mg472,00€50mg655,00€100mg944,00€200mg1.264,00€Indirubin-3′-oxime
CAS:Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.Fórmula:C16H11N3O2Pureza:98.34%Cor e Forma:SolidPeso molecular:277.28Ref: TM-T9138
1mg44,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg120,00€25mg236,00€50mg356,00€100mg532,00€200mg772,00€Proguanil
CAS:Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .Fórmula:C11H16ClN5Pureza:99.6%Cor e Forma:SolidPeso molecular:253.73Cyclo(-RGDfK)
CAS:Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Fórmula:C27H41N9O7Pureza:95.29% - >99.99%Cor e Forma:SolidPeso molecular:603.67GNF2133 hydrochloride
CAS:GNF2133 hydrochloride: selective oral DYRK1A inhibitor (IC50: 0.0062 μM), boosts β-cell growth and insulin, potential for type 1 diabetes research.Fórmula:C24H31ClN6O2Cor e Forma:SolidPeso molecular:471.0CID44216842
CAS:CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.Fórmula:C22H20BrN3O3SPureza:99.66%Cor e Forma:SolidPeso molecular:486.38Ref: TM-T8930
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg85,00€25mg159,00€50mg244,00€100mg359,00€200mg512,00€N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine
CAS:Novel 2,6-naphthyridine inhibits PKC/PKD, identified by HTS.Fórmula:C23H28N6Pureza:98.35%Cor e Forma:SolidPeso molecular:388.51Thiazovivin
CAS:Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.Fórmula:C15H13N5OSPureza:98.00%Cor e Forma:SolidPeso molecular:311.36Ref: TM-T2155
1mg34,00€2mg46,00€5mg64,00€1mL*10mM (DMSO)70,00€10mg98,00€25mg180,00€50mg304,00€100mg444,00€VLX1570
CAS:VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM to 8.6 uM. It has potent inhibition for USP14.Fórmula:C23H17F2N3O6Pureza:98.53% - 99.91%Cor e Forma:SolidPeso molecular:469.39Ref: TM-T4067
1mg90,00€2mg146,00€5mg245,00€1mL*10mM (DMSO)251,00€10mg385,00€25mg645,00€50mg888,00€100mg1.234,00€Ibezapolstat
CAS:Ibezapolstat (ACX-362E) is an antibiotic with antibacterial activity that inhibits Clostridium difficile.Fórmula:C18H20Cl2N6O2Pureza:98% - 99.429%Cor e Forma:SolidPeso molecular:423.3Ref: TM-T10243
1mg54,00€5mg114,00€1mL*10mM (DMSO)127,00€10mg185,00€25mg369,00€50mg594,00€100mg952,00€CCG-100602
CAS:CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).Fórmula:C21H17ClF6N2O2Pureza:99.58%Cor e Forma:SolidPeso molecular:478.82Ref: TM-T22062
5mg35,00€1mL*10mM (DMSO)40,00€10mg54,00€25mg108,00€50mg178,00€100mg286,00€200mg425,00€Adavosertib
CAS:Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.Fórmula:C27H32N8O2Pureza:98.65% - 99.86%Cor e Forma:SolidPeso molecular:500.6Ref: TM-T2077
5mg46,00€1mL*10mM (DMSO)49,00€10mg66,00€25mg81,00€50mg96,00€100mg110,00€200mg161,00€500mg260,00€Y16
CAS:Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.Fórmula:C24H20N2O3Pureza:98.26% - 99.85%Cor e Forma:SolidPeso molecular:384.43Ref: TM-T3553
1mg34,00€2mg48,00€5mg70,00€1mL*10mM (DMSO)77,00€10mg109,00€25mg177,00€50mg263,00€100mg389,00€Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)
Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.Fórmula:C19H34N8O11Pureza:99.81%Cor e Forma:SolidPeso molecular:550.52Cucurbitacin B
CAS:Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Fórmula:C32H46O8Pureza:97.1% - 99.93%Cor e Forma:SolidPeso molecular:558.70GRGDSP acetate(91037-75-1 free base)
GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.Fórmula:C24H41N9O12Pureza:99.77%Cor e Forma:SolidPeso molecular:647.64BMS-5
CAS:BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.Fórmula:C17H14Cl2F2N4OSPureza:98.01% - 99.88%Cor e Forma:SolidPeso molecular:431.29Ref: TM-T4598
1mg40,00€2mg52,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg116,00€25mg188,00€50mg281,00€100mg420,00€2′-Deoxy-2′-fluoroguanosine
CAS:2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM).Fórmula:C10H12FN5O4Pureza:99.89%Cor e Forma:SolidPeso molecular:285.232-Aminofluorene
CAS:2-Aminofluorene (2-Fluorenamine) is a biochemical.Fórmula:C13H11NPureza:99.9%Cor e Forma:Light Yellow CrystallinePeso molecular:181.23CCT245737
CAS:CCT245737 is an orally active, selective Chk1 inhibitor, and is >1,000-fold selective over CHK2 and CDK1.Cost-effective and quality-assured.Fórmula:C16H16F3N7OPureza:98.28% - 99.93%Cor e Forma:SolidPeso molecular:379.34Ref: TM-T7080
1mg37,00€2mg49,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg113,00€25mg213,00€50mg350,00€100mg523,00€Monastrol
CAS:Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Fórmula:C14H16N2O3SPureza:98.02% - 98.59%Cor e Forma:SolidPeso molecular:292.35Ref: TM-T4048
1mg46,00€5mg73,00€10mg92,00€1mL*10mM (DMSO)93,00€25mg178,00€50mg295,00€100mg477,00€500mg1.018,00€CK7
CAS:CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.Fórmula:C14H12N6O2SPureza:99.54%Cor e Forma:SolidPeso molecular:328.35Ref: TM-T9615
1mg50,00€5mg114,00€1mL*10mM (DMSO)126,00€10mg177,00€25mg356,00€50mg557,00€100mg858,00€200mg1.153,00€THAL-SNS-032
CAS:THAL-SNS-032 is a selective CDK9 degrader PROTAC.Fórmula:C40H52N8O10S2Pureza:99.68%Cor e Forma:SolidPeso molecular:869.02Ref: TM-T17069
1mg110,00€5mg259,00€10mg389,00€1mL*10mM (DMSO)389,00€25mg622,00€50mg884,00€100mg1.198,00€DUB-IN-3
CAS:DUB-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor and the IC50 for USP8 is 0.56 μM.Fórmula:C16H9N5OPureza:99.34%Cor e Forma:SolidPeso molecular:287.28Ref: TM-T11112
1mg130,00€2mg178,00€5mg309,00€1mL*10mM (DMSO)324,00€10mg442,00€25mg705,00€50mg982,00€100mg1.333,00€500mg2.655,00€AUZ 454
CAS:AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50/18.6/15.4/9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.Fórmula:C24H26F3N7O2Pureza:99.59%Cor e Forma:SolidPeso molecular:501.5P 22077
CAS:P 22077 (P22077) is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM. It also inhibits the closely related USP47.Fórmula:C12H7F2NO3S2Pureza:97.9% - 99.64%Cor e Forma:SolidPeso molecular:315.32LDC-4297 HCl (1453834-21-3(free base))
LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.
Fórmula:C23H29ClN8OPureza:100%Cor e Forma:SolidPeso molecular:469.026-AZATHYMINE
CAS:6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.Fórmula:C4H5N3O2Pureza:99.47%Cor e Forma:SolidPeso molecular:127.1TR-14035
CAS:TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).Fórmula:C24H21Cl2NO5Pureza:98.98%Cor e Forma:SolidPeso molecular:474.33Ref: TM-T5310
1mg50,00€5mg99,00€1mL*10mM (DMSO)102,00€10mg152,00€25mg245,00€50mg353,00€100mg492,00€200mg700,00€CX-5461
CAS:CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.Fórmula:C27H27N7O2SPureza:95.44% - 99.4%Cor e Forma:SolidPeso molecular:513.61Indisulam
CAS:Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.Fórmula:C14H12ClN3O4S2Pureza:98.68% - 99.77%Cor e Forma:SolidPeso molecular:385.85Ref: TM-T4321
1mg34,00€2mg43,00€5mg63,00€1mL*10mM (DMSO)69,00€10mg88,00€25mg130,00€50mg198,00€100mg298,00€RKI-1447
CAS:RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.Fórmula:C16H14N4O2SPureza:98% - 99.73%Cor e Forma:SolidPeso molecular:326.37Ref: TM-T1898
5mg49,00€1mL*10mM (DMSO)54,00€10mg93,00€25mg177,00€50mg295,00€100mg391,00€200mg494,00€500mg797,00€Risdiplam
CAS:Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.Fórmula:C22H23N7OPureza:98.68% - 99.64%Cor e Forma:SolidPeso molecular:401.46BVDV-IN-1
CAS:BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.Fórmula:C20H22N4OPureza:98.43%Cor e Forma:SolidPeso molecular:334.41Ref: TM-T9103
1mg38,00€5mg86,00€1mL*10mM (DMSO)95,00€10mg124,00€25mg241,00€50mg355,00€100mg507,00€200mg687,00€NVP-LCQ195
CAS:NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).Fórmula:C17H19Cl2N5O4SPureza:99.56% - 99.85%Cor e Forma:SolidPeso molecular:460.33Ref: TM-TQ0068
1mg46,00€5mg92,00€1mL*10mM (DMSO)94,00€10mg138,00€25mg255,00€50mg374,00€100mg533,00€200mg705,00€Deoxythymidine triphosphate
CAS:Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.Fórmula:C10H17N2O14P3·XNaPureza:99.78%Cor e Forma:White Amorphous PowderPeso molecular:482.17（free base）Ro3280
CAS:Ro3280 (Ro5203280) is an effective, specific inhibitor of PLK1(IC50=3, Kd=0.09 nM).Fórmula:C27H35F2N7O3Pureza:97.1% - >99.99%Cor e Forma:SolidPeso molecular:543.61Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Fórmula:C25H21FN6O2SPureza:96.17% - 97.49%Cor e Forma:SolidPeso molecular:488.54Dalpiciclib hydrochloride
Dalpiciclib (SHR-6390) HCl is an oral CDK4/6 inhibitor with IC50s of 12.4/9.9 nM, an antitumor for breast and esophageal cancers.Fórmula:C25H31ClN6O2Cor e Forma:SolidPeso molecular:483.01MLN8054
CAS:MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Fórmula:C25H15ClF2N4O2Pureza:98.07% - 98.26%Cor e Forma:SolidPeso molecular:476.86Ref: TM-T6315
1mg50,00€2mg67,00€5mg84,00€1mL*10mM (DMSO)88,00€10mg120,00€25mg220,00€50mg356,00€100mg537,00€TCID
CAS:TCID (UCH-L3 Inhibitor)(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold selectivity to L1.Fórmula:C9H2Cl4O2Pureza:99.34%Cor e Forma:SolidPeso molecular:283.92PND-1186
CAS:PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Fórmula:C25H26F3N5O3Pureza:99.14% - 99.75%Cor e Forma:SolidPeso molecular:501.5SNS-314
CAS:SNS-314 inhibits Aurora kinases A and B, blocking cell division in AK-overexpressing tumors.Fórmula:C18H15ClN6OS2Pureza:98%Cor e Forma:SolidPeso molecular:430.93Aurora kinase inhibitor-3
CAS:Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,Fórmula:C21H18F3N5OPureza:98.91%Cor e Forma:SolidPeso molecular:413.4Ref: TM-T5524
1mg66,00€2mg89,00€5mg152,00€1mL*10mM (DMSO)167,00€10mg236,00€25mg401,00€50mg580,00€100mg797,00€200mg1.099,00€STAMBP-IN-1
CAS:STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release afterFórmula:C27H28N4O4SPureza:99.64%Cor e Forma:SolidPeso molecular:504.6Ref: TM-T8706
1mg67,00€5mg152,00€1mL*10mM (DMSO)192,00€10mg236,00€25mg507,00€50mg730,00€100mg1.018,00€Abemaciclib
CAS:Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity.Fórmula:C27H32F2N8Pureza:99.43% - 99.87%Cor e Forma:SolidPeso molecular:506.59GSK2850163 hydrochloride
CAS:GSK2850163 hydrochloride is a novel IRE1α inhibitor with IC50 of 20 nM for kinase and 200 nM for RNA enzyme.Fórmula:C24H30Cl3N3OCor e Forma:SolidPeso molecular:482.87RNase L-IN-2
CAS:RNase L-IN-2 activates RNase L at 22 uM, has antiviral effects on various RNA viruses, non-toxic at effective levels.Fórmula:C16H14N2O2SPureza:98.81%Cor e Forma:SolidPeso molecular:298.36Ref: TM-T8591
1mg120,00€1mL*10mM (DMSO)243,00€5mg264,00€10mg395,00€25mg627,00€50mg890,00€100mg1.198,00€200mg1.603,00€THZ1
CAS:THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.Fórmula:C31H28ClN7O2Pureza:97.42% - 99.27%Cor e Forma:SolidPeso molecular:566.05NY2267
CAS:NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethylFórmula:C38H43N3O6Pureza:99.16% - 99.27%Cor e Forma:SolidPeso molecular:637.76A-205804
CAS:A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.Fórmula:C15H12N2OS2Pureza:98.07% - 98.52%Cor e Forma:SolidPeso molecular:300.4Ref: TM-T2254
2mg42,00€5mg50,00€1mL*10mM (DMSO)67,00€10mg77,00€25mg152,00€50mg258,00€100mg505,00€500mg1.108,00€TH5427 hydrochloride
CAS:TH5427 HCl inhibits NUDT5 with 29 nM IC50; 690x more selective over MTH1; blocks ATP in breast cancer cells, hindering growth.Fórmula:C20H21Cl3N8O3Cor e Forma:SolidPeso molecular:527.79OSU-T315
CAS:OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Fórmula:C30H30F3N5OPureza:98.69%Cor e Forma:SolidPeso molecular:533.59Ref: TM-T5485
1mg88,00€5mg187,00€1mL*10mM (DMSO)220,00€10mg298,00€25mg533,00€50mg755,00€100mg1.008,00€200mg1.359,00€HAMNO
CAS:HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).Fórmula:C17H13NO2Pureza:99.96%Cor e Forma:SolidPeso molecular:263.29IMT1B
CAS:IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.Fórmula:C24H21ClFNO6Pureza:98.26% - 99.83%Cor e Forma:SolidPeso molecular:473.88Ref: TM-T8842
1mg138,00€5mg295,00€1mL*10mM (DMSO)309,00€10mg505,00€25mg733,00€50mg888,00€100mg1.251,00€AS2863619
CAS:AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.Fórmula:C16H14Cl2N8OPureza:>99.99%Cor e Forma:SolidPeso molecular:405.24Ref: TM-T8378
1mg124,00€2mg170,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg409,00€25mg677,00€50mg954,00€100mg1.288,00€Y16 acetate(429653-73-6 free base)
Y16 acetate(429653-73-6 free base) is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoAFórmula:C51H74N14O13Pureza:98%Cor e Forma:SolidPeso molecular:1091.24BRD9876
CAS:BRD9876 is a selective inhibitor of MM1S growth.Fórmula:C16H14N2Pureza:97.81%Cor e Forma:SolidPeso molecular:234.33-Methylcytidine
CAS:3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.Fórmula:C10H15N3O5Pureza:99.52%Cor e Forma:SolidPeso molecular:257.24NSC23005 Sodium
CAS:NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.Fórmula:C13H16NNaO4SPureza:99.64%Cor e Forma:SolidPeso molecular:305.32HMN-176
CAS:HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).Fórmula:C20H18N2O4SPureza:98.92% - 98.99%Cor e Forma:SolidPeso molecular:382.43Ref: TM-T3643
1mg40,00€2mg52,00€1mL*10mM (DMSO)74,00€5mg84,00€10mg113,00€25mg178,00€50mg333,00€100mg495,00€500mg1.071,00€Pritelivir
CAS:Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).Fórmula:C18H18N4O3S2Pureza:97.96% - 99.42%Cor e Forma:SolidPeso molecular:402.49AI-10-49
CAS:AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.Fórmula:C30H22F6N6O5Pureza:97.14%Cor e Forma:SolidPeso molecular:660.52Ref: TM-T6753
2mg38,00€5mg57,00€1mL*10mM (DMSO)84,00€10mg92,00€25mg160,00€50mg231,00€100mg343,00€200mg485,00€Senexin A
CAS:Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.Fórmula:C17H14N4Pureza:99.74%Cor e Forma:SolidPeso molecular:274.32Ref: TM-T5673
1mg34,00€1mL*10mM (DMSO)71,00€5mg73,00€10mg94,00€25mg177,00€50mg323,00€100mg460,00€200mg622,00€RK33
CAS:"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."Fórmula:C23H20N6O3Pureza:99.04% - 99.72%Cor e Forma:SolidPeso molecular:428.44LY2334737
CAS:LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.Fórmula:C17H25F2N3O5Pureza:98.82%Cor e Forma:SolidPeso molecular:389.39Ref: TM-T4061
1mg35,00€5mg79,00€1mL*10mM (DMSO)94,00€10mg111,00€25mg215,00€50mg319,00€100mg442,00€200mg583,00€T-5224
CAS:T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcriptionFórmula:C29H27NO8Pureza:97.88% - 99.29%Cor e Forma:SolidPeso molecular:517.53Ref: TM-T5416
1mg48,00€5mg96,00€1mL*10mM (DMSO)107,00€10mg144,00€25mg254,00€50mg424,00€100mg627,00€200mg998,00€BS-181 hydrochloride
CAS:BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.Fórmula:C22H32N6·HClPureza:99.21%Cor e Forma:SolidPeso molecular:416.99Ref: TM-T6162
200mgA consultar1mg37,00€2mg52,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg116,00€25mg250,00€50mg416,00€100mg645,00€HMN-214
CAS:HMN-214 (IVX-214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.Fórmula:C22H20N2O5SPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:424.47Ref: TM-T2438
1mg38,00€2mg50,00€5mg80,00€1mL*10mM (DMSO)87,00€10mg117,00€25mg207,00€50mg333,00€100mg477,00€500mg1.063,00€TAK-960
CAS:TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.Fórmula:C27H34F3N7O3Pureza:97.06%Cor e Forma:SolidPeso molecular:561.6Ref: TM-T7200
1mg60,00€2mg85,00€5mg114,00€10mg161,00€1mL*10mM (DMSO)161,00€25mg279,00€50mg464,00€100mg672,00€ZCL278
CAS:ZCL278 is a selective Cdc42 GTPase inhibitor.Fórmula:C21H19BrClN5O4S2Pureza:96.29% - 99.72%Cor e Forma:SolidPeso molecular:584.89Ref: TM-T1855
5mg52,00€10mg74,00€1mL*10mM (DMSO)74,00€25mg129,00€50mg210,00€100mg294,00€200mg470,00€500mg763,00€Cyclo(-RGDfK) TFA
CAS:Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).Fórmula:C29H42F3N9O9Pureza:98.99% - 99.54%Cor e Forma:SolidPeso molecular:717.69Triazavirin
CAS:Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Fórmula:C5H7N6NaO5SPureza:99.55%Cor e Forma:SolidPeso molecular:286.2Netarsudil free base
CAS:Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.Fórmula:C28H27N3O3Cor e Forma:SolidPeso molecular:453.53Pyridostatin TFA
CAS:Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Cor e Forma:SolidPeso molecular:938.71Hydroxyfasudil
CAS:Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).Fórmula:C14H17N3O3SPureza:98.13%Cor e Forma:SolidPeso molecular:307.37HQ461
CAS:HQ461, a molecular glue, boosts CDK12-DDB1 binding, lowers cyclin K, impedes CDK12 phosphorylation, hinders DNA repair genes, and induces cell death.Fórmula:C15H15N5OS2Pureza:98.11%Cor e Forma:SolidPeso molecular:345.44Ref: TM-T9849
1mg43,00€2mg56,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg144,00€25mg319,00€50mg537,00€100mg767,00€500mg1.558,00€AG-636
CAS:AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.Fórmula:C21H17N3O2Pureza:99.19%Cor e Forma:SolidPeso molecular:343.38TAK-960 hydrochloride
CAS:TAK-960 hydrochloride is an oral, potent PLK1 inhibitor with IC50 of 0.8 nM, effective against various tumor cells and xenografts.Fórmula:C27H35ClF3N7O3Cor e Forma:SolidPeso molecular:598.06BUR1
CAS:BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.Fórmula:C16H17N5Pureza:90%Cor e Forma:SolidPeso molecular:279.34BMH-21
CAS:BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Fórmula:C21H20N4O2Pureza:99.47% - 99.84%Cor e Forma:SolidPeso molecular:360.41P18IN011
CAS:P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).
Fórmula:C15H12N2O5SPureza:97.63%Cor e Forma:SolidPeso molecular:332.33DUB-IN-2
CAS:Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor.Fórmula:C15H9N5OPureza:98.96%Cor e Forma:SolidPeso molecular:275.26Ref: TM-T11111
1mg54,00€5mg155,00€1mL*10mM (DMSO)169,00€10mg233,00€25mg467,00€50mg682,00€100mg990,00€TH588 hydrochloride
CAS:TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.Fórmula:C13H13Cl3N4Cor e Forma:SolidPeso molecular:331.63Hydroxyfasudil Hydrochloride
CAS:Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).Fórmula:C14H18ClN3O3SPureza:98.05%Cor e Forma:SolidPeso molecular:343.83α2β1 Integrin Ligand Peptide acetate
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor.Fórmula:C16H26N4O11Pureza:98.46%Cor e Forma:SolidPeso molecular:450.4DUB-IN-1
CAS:DUB-IN-1, with an IC50 value of 0.24 for USP8, is an active inhibitor of ubiquitin-specific protease (USPs).Fórmula:C20H11N5OPureza:98.33% - 98.96%Cor e Forma:SolidPeso molecular:337.33Ref: TM-T11110
1mg62,00€5mg110,00€1mL*10mM (DMSO)122,00€10mg173,00€25mg334,00€50mg469,00€100mg618,00€200mg848,00€PHA-680632
CAS:PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.Fórmula:C28H35N7O2Pureza:98.2%Cor e Forma:SolidPeso molecular:501.62Purvalanol B
CAS:Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)Fórmula:C20H25ClN6O3Pureza:98.95%Cor e Forma:SolidPeso molecular:432.9Ref: TM-T7167
1mg34,00€2mg46,00€5mg67,00€1mL*10mM (DMSO)75,00€10mg90,00€25mg130,00€50mg203,00€100mg305,00€200mg447,00€FOY 251
CAS:FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.Fórmula:C17H19N3O7SPureza:97.11% - 99.33%Cor e Forma:SolidPeso molecular:409.41Ref: TM-T8676
1mg51,00€5mg110,00€1mL*10mM (DMSO)126,00€10mg177,00€25mg300,00€50mg424,00€100mg605,00€500mg1.198,00€Trimethoprim sulfate
CAS:Trimethoprim sulfate, a dihydrofolate reductase inhibitor, treats bacterial infections and sometimes malaria; may depress hematopoiesis.Fórmula:C28H38N8O10SCor e Forma:SolidPeso molecular:678.72
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