Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(94 produtos)
- CDK(500 produtos)
- Ciclo celular/Parada(4 produtos)
- Chk(42 produtos)
- DYRK(48 produtos)
- Dinamina(23 produtos)
- Ferroptose(215 produtos)
- HSP(169 produtos)
- Integrinas(224 produtos)
- Cinesina(66 produtos)
- LIM Quinase(19 produtos)
- Microtúbulo associado(261 produtos)
- PKC(102 produtos)
- PLK(28 produtos)
- ROCK(70 produtos)
- Rho(2 produtos)
- Wee1(15 produtos)
- c-Myc(69 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"
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PF-2771
CAS:<p>PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.</p>Fórmula:C29H36ClN5O4Pureza:98%Cor e Forma:SolidPeso molecular:554.08DNA Gyrase-IN-5
CAS:<p>DNA Gyrase-IN-5 is a potent inhibitor of DNA gyrase (IC50: 0.10 μM) and has an antibacterial effect on both wild-type and drug-resistant strains.</p>Fórmula:C25H15BrClN5Cor e Forma:SolidPeso molecular:500.78Syntelin
CAS:<p>Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.</p>Fórmula:C21H20N6O2S3Cor e Forma:SolidPeso molecular:484.62Zalunfiban
CAS:<p>RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.</p>Fórmula:C16H18N8O2SCor e Forma:SolidPeso molecular:386.43MDK6204
CAS:<p>MDK6204 is a selective inhibitor of CLK1 and CLK2.</p>Fórmula:C20H20N6OPureza:98%Cor e Forma:SolidPeso molecular:360.41Cylindrospermopsin
CAS:<p>Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.</p>Fórmula:C15H21N5O7SCor e Forma:SolidPeso molecular:415.42Cdc7-IN-4
CAS:<p>Cdc7-IN-4 is a potent inhibitor of Cdc7 kinase.</p>Fórmula:C22H24F3N5O4Pureza:98%Cor e Forma:SolidPeso molecular:479.45Valategrast
CAS:<p>Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.</p>Fórmula:C30H32Cl3N3O4Pureza:98%Cor e Forma:SolidPeso molecular:604.95Cyclapolin 9
CAS:<p>Cyclapolin 9: Selective PLK1 inhibitor, IC50 500 nM, ATP-competitive, inactive against other kinases.</p>Fórmula:C9H4F3N3O4SPureza:99.5%Cor e Forma:SolidPeso molecular:307.21Binucleine 2
CAS:<p>Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.</p>Fórmula:C13H11ClFN5Cor e Forma:SolidPeso molecular:291.71IRE1α kinase-IN-7
CAS:<p>IRE1α kinase-IN-7 is a chemical compound functioning as an inhibitor of IRE1α kinase, primarily utilized in the research of diseases related to endoplasmic</p>Fórmula:C28H25F3N6OCor e Forma:SolidPeso molecular:518.531-Methylcytosine
CAS:<p>1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with</p>Fórmula:C5H7N3OPureza:99.88%Cor e Forma:SolidPeso molecular:125.13ANI-7
CAS:<p>ANI-7, an AhR pathway activator, selectively impedes MCF-7 breast cancer cell growth (GI50: 0.56 μM).</p>Fórmula:C13H8Cl2N2Pureza:99.07%Cor e Forma:SolidPeso molecular:263.12WF-536 Hydrochloride
CAS:<p>WF-536 Hydrochloride, a novel inhibitor of ROCK, inhibits tumour metastasis in some animal models.</p>Fórmula:C14H16ClN3OCor e Forma:SolidPeso molecular:277.75BA-1049
CAS:<p>BA-1049 is a selective ROCK2 inhibitor.</p>Fórmula:C16H21N3O2SCor e Forma:SolidPeso molecular:319.42M443
CAS:<p>M443 is a potent small molecule inhibitor of MRK that inhibits radiation-induced activation of p38 and Chk2 and can be used in cancer research.</p>Fórmula:C31H30F3N7O2Pureza:98.95%Cor e Forma:SolidPeso molecular:589.61XIE18-6
CAS:<p>XIE18-6 is a novel INK4C inhibitor that blocks p18 activity and promotes ex vivo expansion of human and murine hematopoietic stem cells.</p>Fórmula:C18H15NO6SPureza:99.712%Cor e Forma:SolidPeso molecular:373.38CI-898 HCl
CAS:<p>CI-898 HCl: lipophilic antifolate, DHFR inhibitor, effective on methotrexate-resistant cancers, synergizes with other drugs in advanced P338 leukemia.</p>Fórmula:C19H26Cl3N5O3Cor e Forma:SolidPeso molecular:478.8CDK4/6-IN-14
CAS:<p>CDK4/6-IN-14: potent CDK4/6 inhibitor, IC50s 10/16 nM, >60-fold selectivity over CDKs 1/2/7/9, selective across 205 kinases.</p>Fórmula:C24H27ClFN7OCor e Forma:SolidPeso molecular:483.97IRE1α kinase-IN-9
CAS:<p>IRE1α kinase-IN-9 (compound 2) is a potent inhibitor of IRE-1α, demonstrating an average IC50 value of less than 0.1 μM.</p>Fórmula:C24H24N2O6Pureza:98%Cor e Forma:SolidPeso molecular:436.46Trimetrexate glucuronate
CAS:<p>Trimetrexate glucuronate, a folic acid foe, blocks DNA/RNA synthesis by inhibiting purine and thymidylic acid production, may fight tumors.</p>Fórmula:C25H33N5O10Cor e Forma:SolidPeso molecular:563.564TCS 2314
CAS:<p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>Fórmula:C28H34N4O6Pureza:98%Cor e Forma:SolidPeso molecular:522.59Thiarabine
CAS:<p>Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.</p>Fórmula:C9H13N3O4SPureza:98%Cor e Forma:SolidPeso molecular:259.28ROCK-IN-4
CAS:<p>ROCK-IN-4: Inhibits ROCK, sustains NO release, disrupts F-actin, hinders HTM cell respiration, aids glaucoma research.</p>Fórmula:C20H26ClFN4O7SCor e Forma:SolidPeso molecular:520.96USP28-IN-2
CAS:<p>USP28-IN-2 selectively inhibits USP28 (IC50=0.3 μM), degrades c-Myc, kills cancer cells, lowers ankyrin-1/2, and enhances Regorafenib effects.</p>Fórmula:C23H20Cl2N2O3SCor e Forma:SolidPeso molecular:475.39IRE1α kinase-IN-8
CAS:<p>IRE1α kinase-IN-8, a benzoheterocyclecarboxaldehyde derivative, serves as a potent inhibitor of IRE-1α.</p>Fórmula:C23H22N2O5Pureza:98%Cor e Forma:SolidPeso molecular:406.43Dihydro-5-azacytidine acetate
CAS:<p>Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1</p>Fórmula:C10H18N4O7Pureza:98%Cor e Forma:SolidPeso molecular:306.27Cdc7-IN-5
CAS:<p>Cdc7-IN-5: potent Cdc7 serine-threonine kinase inhibitor, critical for starting DNA replication.</p>Fórmula:C25H23N3O5Pureza:97.15%Cor e Forma:SolidPeso molecular:445.47JH-XIV-68-3
CAS:<p>JH-XIV-68-3: Selective DYRK1A/B inhibitor; effective in HNSCC cell lines.</p>Fórmula:C21H17F3N8OCor e Forma:SolidPeso molecular:454.41CM03
CAS:<p>CM03 is a cell-selective G-quadruplex ligand with anti-cancer activity, stabilizing G4 genes, useful in pancreatic cancer research.</p>Fórmula:C34H44N6O6Pureza:98.65%Cor e Forma:SolidPeso molecular:632.75Akt1&PKA-IN-2
CAS:<p>Akt1&PKA-IN-2 ((R)-29) inhibits AKT1, PKAα, CDK2 with IC50s: 0.007, 0.01, 0.69 µM respectively.</p>Fórmula:C20H17Cl2N3OCor e Forma:SolidPeso molecular:386.27CDK1-IN-1
CAS:<p>CDK1-IN-7 inhibits CDK1 at 161.2 nM, triggers p53-dependent apoptosis, and selectively targets tumor growth.</p>Fórmula:C27H23N5O3Cor e Forma:SolidPeso molecular:465.5Werner syndrome RecQ helicase-IN-4
CAS:<p>Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.</p>Fórmula:C32H33F3N8O5Pureza:98.27%Cor e Forma:SolidPeso molecular:666.65FLDP-5
CAS:<p>FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.</p>Fórmula:C21H21NO5Cor e Forma:SolidPeso molecular:367.45-Aminouridine
CAS:<p>5-Aminouridine (4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)) modifies nucleobases and is incorporated into the target DNA.</p>Fórmula:C9H13N3O6Pureza:99.53%Cor e Forma:SolidPeso molecular:259.22CDK7-IN-2
CAS:<p>CDK7-IN-2 inhibits CDK7, essential for RNA polymerase II activation and cell cycle control, with cancer research potential.</p>Fórmula:C26H39N7O3Cor e Forma:SolidPeso molecular:497.63CB10-277
CAS:<p>CB10-277 is a synthetic anti-cancer drug related to dacarbazine that alkylates DNA, inhibits DNA replication and repair, and may block DNA synthesis.</p>Fórmula:C9H11N3O2Cor e Forma:SolidPeso molecular:193.2Edatrexate
CAS:<p>Edatrexate (CGP 30694), a Methotrexate analog, combats MTX-resistant tumors and researches various cancers.</p>Fórmula:C22H25N7O5Cor e Forma:SolidPeso molecular:467.48Balamapimod
CAS:<p>Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.</p>Fórmula:C30H32ClN7OSPureza:98%Cor e Forma:SolidPeso molecular:574.14HBV-IN-21
CAS:<p>HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).</p>Fórmula:C17H17FN4OS2Cor e Forma:SolidPeso molecular:376.47CDK4/6-IN-7
CAS:<p>CDK4/6-IN-7 is an oral, potent CDK4/6 inhibitor with IC50s of 1.58/4.09 nM, crucial for breast cancer studies.</p>Fórmula:C18H18ClN5O3Cor e Forma:SolidPeso molecular:387.82BI8622
CAS:<p>BI8622 is a HUWE1 antagonist that restores levels of RP2 mutants in retinal cell lines and inhibits cellular activation of NLRP3 and AIM2 inflammatory vesicles.</p>Fórmula:C25H26N6OPureza:98.28%Cor e Forma:SolidPeso molecular:426.51DHODH-IN-4
CAS:<p>DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.</p>Fórmula:C17H12Cl2N2O2Pureza:99.34%Cor e Forma:SolidPeso molecular:347.2Enocitabine
CAS:<p>Enocitabine is a nucleoside analog.</p>Fórmula:C31H55N3O6Pureza:97.22%Cor e Forma:SolidPeso molecular:565.78CAY10760
CAS:<p>CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.</p>Fórmula:C28H24ClN3O3Cor e Forma:SolidPeso molecular:485.96SPC-839
CAS:<p>SPC-839 is an IKK-2 Inhibitor with oral activity.</p>Fórmula:C18H14N4O3SCor e Forma:SolidPeso molecular:366.39DHODH-IN-19
CAS:<p>DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)</p>Fórmula:C22H18ClF6N3O3Cor e Forma:SolidPeso molecular:521.84ARN22089
CAS:<p>ARN22089 is an oral active CDC42 GTPase interaction inhibitor that blocks tumour growth in BRAF mutant mouse melanoma models and PDXs in vivo.</p>Fórmula:C23H27N5Pureza:98.37%Cor e Forma:SolidPeso molecular:373.49αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
<p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>Fórmula:C28H35F3N6O8SPureza:98%Cor e Forma:SolidPeso molecular:672.67MTH1-IN-2
CAS:<p>MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.</p>Fórmula:C24H27N3O5SPureza:98%Cor e Forma:SolidPeso molecular:469.55TH470
CAS:<p>TH470, a potent and highly selective inhibitor of LIM kinase 1/2 (LIMK1/2), demonstrates specificity with IC50 values of 9.8 nM for LIMK1 and 13 nM for LIMK2,</p>Fórmula:C30H31N5O5S2Cor e Forma:SolidPeso molecular:605.73Mequindox
CAS:<p>Mequindox is an antimicrobial agent [1]. Mequindox, as an inhibitor of DNA synthesis, induces genotoxicity and carcinogenicity in mice [2].</p>Fórmula:C11H10N2O3Cor e Forma:SolidPeso molecular:218.21Phen-DC3
CAS:<p>Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).</p>Fórmula:C34H26N6O2Pureza:98%Cor e Forma:SolidPeso molecular:550.61cp028
CAS:<p>cp028 inhibits pre-mRNA splicing in vitro.</p>Fórmula:C23H17FN2O4Cor e Forma:SolidPeso molecular:404.39Aurora kinase inhibitor-10
CAS:<p>Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.</p>Fórmula:C21H19F5N6O4SCor e Forma:SolidPeso molecular:546.47Dyrk1A-IN-5
CAS:<p>Potent DYRK1A inhibitor with IC50s: 6 nM overall, 0.5 μM SF3B1, 2.1 μM tau phosphorylation. Useful for Down syndrome studies.</p>Fórmula:C16H9IN2O2Cor e Forma:SolidPeso molecular:388.16Crozbaciclib fumarate
CAS:<p>Crozbaciclib fumarate is a CDK4/6 inhibitor with IC 50 s of 3 and 1 nM, respectively.</p>Fórmula:C32H34F2N6O4Cor e Forma:SolidPeso molecular:604.65SR31527
CAS:<p>SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.</p>Fórmula:C15H14ClN3OSPureza:98%Cor e Forma:SolidPeso molecular:319.81Antitumor agent-84
<p>Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.</p>Fórmula:C24H31N7Cor e Forma:SolidPeso molecular:417.55CRT-0105446
CAS:<p>CRT-0105446 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.</p>Fórmula:C20H18F3N3O2SPureza:98%Cor e Forma:SolidPeso molecular:421.44TCS 2312
CAS:<p>checkpoint kinase 1 (chk1) inhibitor</p>Fórmula:C25H24N4O2Pureza:98%Cor e Forma:SolidPeso molecular:412.48Trimetrexate
CAS:<p>Trimetrexate is an effective competitive inhibitor of bacterial, protozoan, and mammalian dihydrofolate reductase.</p>Fórmula:C19H23N5O3Pureza:98%Cor e Forma:SolidPeso molecular:369.42Akt1&PKA-IN-1
CAS:<p>Akt1&PKA-IN-1 inhibits Akt/PKA: IC50 = 0.03μM (PKAa), 0.11μM (Akt), 9.8μM (CDK2); selective for CDK2.</p>Fórmula:C20H17Cl2N3OCor e Forma:SolidPeso molecular:386.27Laflunimus
CAS:<p>Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.</p>Fórmula:C15H13F3N2O2Pureza:99.86%Cor e Forma:SolidPeso molecular:310.275-Ethynyluridine
CAS:<p>5-Ethynyluridine marks new RNA for RICK, capturing proteins on various RNAs, even nonpolyadenylated types.</p>Fórmula:C11H12N2O6Pureza:99.78%Cor e Forma:SolidPeso molecular:268.22Aurora Kinases-IN-3
CAS:<p>Aurora Kinases-IN-3 is an oral AURKB inhibitor that disrupts its mitotic localization, not its H3 Ser10 phosphorylation.</p>Fórmula:C20H16F3N3O4Cor e Forma:SolidPeso molecular:419.35SRPIN-803
CAS:<p>SRPIN-803 is a selective dual SRPK1 and CK2 inhibitor.</p>Fórmula:C14H9F3N4O3SPureza:98%Cor e Forma:SolidPeso molecular:370.31GSK317354A
CAS:<p>GSK317354A is a GRK2 inhibitor.</p>Fórmula:C25H18F4N6OCor e Forma:SolidPeso molecular:494.44BOP sodium
CAS:<p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>Fórmula:C25H29N3NaO7SCor e Forma:SolidPeso molecular:538.57Integrin-IN-2
CAS:<p>Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.</p>Fórmula:C27H30N4O3Pureza:98%Cor e Forma:SolidPeso molecular:458.55360A iodide
CAS:<p>360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).</p>Fórmula:C27H23I2N5O2Pureza:98%Cor e Forma:SolidPeso molecular:703.31NSC 625987
CAS:<p>Cyclin-dependent kinase (cdk) 4 inhibitor</p>Fórmula:C15H13NO2SPureza:98%Cor e Forma:SolidPeso molecular:271.33CDK8-IN-4
CAS:<p>CDK8-IN-4 is an inhibitor of CDK8 (IC50: 0.2 nM).</p>Fórmula:C20H18N4OCor e Forma:SolidPeso molecular:330.38CDK12-IN-3
CAS:<p>CDK12-IN-3 is a CDK12 inhibitor with anti-tumor activity and can be used for the study of malignant tumors.</p>Fórmula:C23H28F2N8OPureza:99.85%Cor e Forma:SolidPeso molecular:470.52DNA Gyrase-IN-4
CAS:<p>DNA Gyrase-IN-4 inhibits DNA cyclooxygenase (IC50: 0.13 μM) and is effective against Salmonella and E. coli.</p>Fórmula:C22H15Cl2NO4SCor e Forma:SolidPeso molecular:460.33FUBP1-IN-2
CAS:<p>FUBP1-IN-2 hinders FUBP1, affects c-Myc and p21 expression, and depletes polyamines.</p>Fórmula:C26H26ClN3O4Cor e Forma:SolidPeso molecular:479.96Cdc7-IN-1
CAS:<p>Cdc7-IN-1: selective ATP-competitive Cdc7 kinase inhibitor; IC50 0.6 nM at 1mM ATP; induces cancer cell death.</p>Fórmula:C21H16ClN3O4Cor e Forma:SolidPeso molecular:409.82IXA6
CAS:<p>IXA6 is an IRE1/XBP1s agonist with potential vasoprotective activity for the study of neurodegenerative diseases such as Parkinson's disease.</p>Fórmula:C22H20ClN3O3SPureza:98.63%Cor e Forma:SolidPeso molecular:441.93KSI-3716
CAS:<p>KSI-3716 is a c-Myc inhibitor, a bladder chemotherapy agent that blocks the formation of complexes between c-MYC/MAX and target gene promoters.</p>Fórmula:C17H11BrCl2N2O2Pureza:98.94%Cor e Forma:SolidPeso molecular:426.09CLK1/2-IN-3
CAS:<p>CLK1/2-IN-3 (Cpd-3) is a CLK1 and CLK2 inhibitor with antiproliferative activity that inhibits the activity of CLK and SRPK.</p>Fórmula:C21H21N5O2Pureza:99.04%Cor e Forma:SolidPeso molecular:375.42CDK12-IN-E9
CAS:<p>CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux.</p>Fórmula:C24H30N6O2Cor e Forma:SolidPeso molecular:434.53PD-1/PD-L1-IN-NP19
CAS:<p>PD-1/PD-L1-IN-NP19: a PD-1/PD-L1 inhibitor with 12.5 nM IC50, may boost antitumor immunity.</p>Fórmula:C33H31ClN2O4Pureza:98%Cor e Forma:SolidPeso molecular:555.06AS2863619 free base
CAS:<p>AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells.</p>Fórmula:C16H12N8OCor e Forma:SolidPeso molecular:332.325,10-Dideazaaminopterin
CAS:<p>5,10-Dideazaaminopterin is an antileukemic drug.</p>Fórmula:C21H22N6O5Pureza:98%Cor e Forma:SolidPeso molecular:438.44HBV-IN-14
CAS:<p>HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).</p>Fórmula:C22H21ClN2O5Cor e Forma:SolidPeso molecular:428.87Chlorasquin
CAS:<p>Chlorasquin is a dihydrofolate reductase inhibitor.</p>Fórmula:C20H19ClN6O5Pureza:98%Cor e Forma:SolidPeso molecular:458.86Centrinone-B
CAS:<p>Centrinone-B (LCR-323) is a Plk4 inhibitor with potential anticancer activity for the study of triple-negative breast cancer.</p>Fórmula:C27H27F2N7O5S2Pureza:98.71%Cor e Forma:SolidPeso molecular:631.67MMV688845
CAS:<p>MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.</p>Fórmula:C24H25N3O3SCor e Forma:SolidPeso molecular:435.54L 888607 Racemate
CAS:<p>L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.</p>Fórmula:C19H15ClFNO2SCor e Forma:SolidPeso molecular:375.84Ilorasertib hydrochloride
CAS:<p>Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:</p>Fórmula:C25H22ClFN6O2SPureza:98.45%Cor e Forma:SolidPeso molecular:525CLK1-IN-1
CAS:<p>CLK1-IN-1 is a potent and selective inhibitor of the Cdc2-like kinase 1 (CLK1; IC50: 2 nM).</p>Fórmula:C24H16FN5OCor e Forma:SolidPeso molecular:409.42THZ1-R
CAS:<p>THZ1-R is a non-covalent active analogue of THZ1, with the acrylamide group removed from THZ1, not covalently bind to the C312 cysteine residue of CDK7.</p>Fórmula:C31H30ClN7O2Pureza:98%Cor e Forma:SolidPeso molecular:568.07Antibacterial agent 124
CAS:<p>Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.</p>Fórmula:C16H17ClFN3O2Cor e Forma:SolidPeso molecular:337.78JA2131
CAS:<p>JA2131: Small PARG inhibitor, IC50 0.4μM, induces DNA damage, stalls replication, kills cancer cells.</p>Fórmula:C13H19N5O2S2Cor e Forma:SolidPeso molecular:341.45Poloxipan
CAS:<p>Poloxipan inhibits PLK1 (IC50: 3.2µM), PLK2 (1.7µM), PLK3 (3µM); minimal effect on Chk2, STAT1, STAT5b, Lck.</p>Fórmula:C14H10BrN3O3SCor e Forma:SolidPeso molecular:380.22Kif15-IN-1
CAS:<p>Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.</p>Fórmula:C20H22N4O5SPureza:99.39% - 99.39%Cor e Forma:SolidPeso molecular:430.48KIF18A-IN-3
CAS:<p>KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.</p>Fórmula:C28H38N4O5S2Pureza:98.45%Cor e Forma:SolidPeso molecular:574.76BMS-688521
CAS:<p>BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.</p>Fórmula:C26H19Cl2N5O4Pureza:98.87%Cor e Forma:SolidPeso molecular:536.37CDK8/19-IN-51
CAS:<p>CDK8/19-IN-51 is a CDK8 and CDK19 inhibitor with anticancer activity, used in research on colorectal and gastric cancers.</p>Fórmula:C23H22N6O2Pureza:98.65% - 99.62%Cor e Forma:SoildPeso molecular:414.46UR-3216
CAS:<p>UR-3216 is a prodrug, selectively antagonizing GPIIb/IIIa receptors orally, with its active form, UR-2992, binding tightly to platelets.</p>Fórmula:C27H29N7O7Pureza:98%Cor e Forma:SolidPeso molecular:563.56
