Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(116 produtos)
- CDK(548 produtos)
- Ciclo celular/Parada(5 produtos)
- Chk(49 produtos)
- DYRK(46 produtos)
- Dinamina(27 produtos)
- Ferroptose(233 produtos)
- HSP(180 produtos)
- Integrinas(276 produtos)
- Cinesina(87 produtos)
- LIM Quinase(21 produtos)
- Microtúbulo associado(274 produtos)
- PKC(128 produtos)
- PLK(25 produtos)
- ROCK(61 produtos)
- Rho(6 produtos)
- Wee1(14 produtos)
- c-Myc(77 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3937 produtos de "Ciclo celular/Ponto de verificação"
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Z62954982
CAS:Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteriesFórmula:C20H21N3O5SPureza:98.28%Cor e Forma:SolidPeso molecular:415.46Ref: TM-T37113
1mg35,00€5mg75,00€1mL*10mM (DMSO)87,00€10mg105,00€25mg173,00€50mg255,00€100mg371,00€200mg530,00€Tenidap
CAS:Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.Fórmula:C14H9ClN2O3SPureza:98.56% - 99.42%Cor e Forma:SolidPeso molecular:320.75N6-(p-Methoxybenzyl)adenosine
CAS:Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormoneFórmula:C18H21N5O5Pureza:99.79%Cor e Forma:SolidPeso molecular:387.39Ref: TM-TNU0430
1mg141,00€2mg203,00€5mg344,00€10mg505,00€25mg797,00€50mg1.044,00€100mg1.431,00€200mg1.953,00€PDD00017273
CAS:PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.Fórmula:C23H26N6O4S2Pureza:99.14% - 99.21%Cor e Forma:SolidPeso molecular:514.62Ref: TM-T5700
5mg78,00€1mL*10mM (DMSO)92,00€10mg130,00€25mg269,00€50mg403,00€100mg580,00€500mg1.198,00€O6-Methyldeoxy guanosine
CAS:O6-Methyldeoxy guanosine, a deoxypurine nucleoside, is a weak inhibitor of the removal of O6-methylguanine from methylated DNA by rat liver enzymes in vitro.Fórmula:C11H15N5O4Pureza:99.57%Cor e Forma:SolidPeso molecular:281.272'-Deoxy-N4-methylcytidine
CAS:2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.Fórmula:C10H15N3O4Pureza:99.61%Cor e Forma:SolidPeso molecular:241.242'-Deoxy-2-iodoadenosine
CAS:2'-Deoxy-2-iodoadenosine is a purine nucleoside analog with potential antimicrobial, antioxidant and anti-leukemic activities.Fórmula:C10H12IN5O3Pureza:99.37%Cor e Forma:SolidPeso molecular:377.142'-C-β-Methylguanosine
CAS:2'-C-beta-Methylguanosine (2'-C-Methylguanosine), with antiviral activity, inhibits dengue virus 2.Fórmula:C11H15N5O5Pureza:99.37%Cor e Forma:SolidPeso molecular:297.27DS44960156
CAS:DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.Fórmula:C20H15NO5Pureza:99.13%Cor e Forma:SolidPeso molecular:349.34Ref: TM-T37655
1mg73,00€5mg160,00€1mL*10mM (DMSO)170,00€10mg236,00€25mg409,00€50mg595,00€100mg858,00€9-(β-D-Xylofuranosyl)adenine
CAS:9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine hasFórmula:C10H13N5O4Pureza:99.97%Cor e Forma:SolidPeso molecular:267.24USP1-IN-2
CAS:USP1-IN-2 is a potent USP1 inhibitor with potential anti-tumor activity for the study of cancer.Fórmula:C26H22F4N6OPureza:99.69% - 99.88%Cor e Forma:SolidPeso molecular:510.486LSN2839567
CAS:LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.Fórmula:C25H28F2N8Pureza:99.14%Cor e Forma:SolidPeso molecular:478.54RO0270608
CAS:RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.Fórmula:C24H19Cl3N2O4Pureza:98.26%Cor e Forma:SolidPeso molecular:505.78P-2'-deoxyribose
CAS:P-2'-deoxyribose (P-Nucleoside) is a deoxyribose that is widely found in organisms.Fórmula:C11H15N3O5Pureza:99.71%Cor e Forma:SolidPeso molecular:269.25Ref: TM-TNU1281
1mg109,00€2mg160,00€5mg261,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.431,00€5-Bromo-2',3',5'-tri-O-acetyluridine
CAS:5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that can be used to explore explore improve Parkinson's disease.Fórmula:C15H17BrN2O9Pureza:99%Cor e Forma:SolidPeso molecular:449.21Braco-19
CAS:Braco-19 is a telomerase/telomere inhibitor and an inhibitor of HAdV viral replication with antiviral activity that reduces lipid vacuolization in adipocytes, inhibits proliferation and decreases telomerase activity in human glioblastoma cells.Fórmula:C35H43N7O2Pureza:97.01%Cor e Forma:SolidPeso molecular:593.765-Bromouridine
CAS:5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.Fórmula:C9H11BrN2O6Pureza:99.89%Cor e Forma:White PowderPeso molecular:323.1Bexotegrast
CAS:Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).Fórmula:C27H36N6O3Pureza:99.53%Cor e Forma:SolidPeso molecular:492.612'-O-(2-Methoxyethyl)adenosine
CAS:2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.Fórmula:C13H19N5O5Pureza:99.35%Cor e Forma:SolidPeso molecular:325.32N6-Methyl-2'-O-methyladenosine
CAS:N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound foundFórmula:C12H17N5O4Pureza:99.97%Cor e Forma:SolidPeso molecular:295.292'-Deoxy-N2-methylguanosine
CAS:2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.Fórmula:C11H15N5O4Pureza:99.79%Cor e Forma:SolidPeso molecular:281.272'-O-Methyl-2-thiouridine
CAS:2'-O-Methyl-2-thiouridine, a purine nucleoside analog present in synthetic thermophilic bacterial tRNAs, is more selective for A than unmodified U.Fórmula:C10H14N2O5SPureza:99.89%Cor e Forma:SolidPeso molecular:274.292',3'-Bis-(O-t-butyldimethylsilyl)uridine
CAS:2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a nucleoside derivative protect the NH2/OH groups of nucleosides.inhibitory on viral replication，AIDS and herpes.Fórmula:C21H40N2O6Si2Pureza:99.88%Cor e Forma:SolidPeso molecular:472.72PolQi2
CAS:PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.Fórmula:C21H16ClN5O3SPureza:99.19%Cor e Forma:SolidPeso molecular:453.9Ref: TM-T84770
1mg84,00€5mg170,00€1mL*10mM (DMSO)195,00€10mg281,00€25mg542,00€50mg757,00€100mg1.044,00€Levomefolate sodium
CAS:Levomefolate sodium (L-5-MTHF sodium) is a dietary supplement that can be used to study megaloblastic anemia and neurological disorders.Fórmula:C20H23N7Na2O6Pureza:98.7%Cor e Forma:SolidPeso molecular:503.42MK-5108
CAS:MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Fórmula:C22H21ClFN3O3SPureza:99.22%Cor e Forma:SolidPeso molecular:461.94Mps1-IN-2
CAS:Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.Fórmula:C26H36N6O3Pureza:96.24% - 99.75%Cor e Forma:SolidPeso molecular:480.6SCH-1473759 hydrochloride
CAS:SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Fórmula:C20H27ClN8OSPureza:98.29%Cor e Forma:SolidPeso molecular:463PF-03814735
CAS:PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.Fórmula:C23H25F3N6O2Pureza:98%Cor e Forma:SolidPeso molecular:474.48Pacanalotamab
CAS:Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.Cor e Forma:LiquidAcapatamab
CAS:Acapatamab (AMG-160) is a Half-Life Extended (HLE) Bispecific T-cell Engager (BiTE) with domains that bind to PSMA and CD3. It exhibits Kd values of 14.8 nM for hPSMA and 22.4 nM for hCD3. This compound is utilized in cancer research.Cor e Forma:LiquidN6-Etheno 2'-deoxyadenosine
CAS:N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.Fórmula:C12H13N5O3Pureza:98%Cor e Forma:SolidPeso molecular:275.26Vibecotamab
CAS:Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.Cor e Forma:LiquidPOSH-IN-1
CAS:POSH-IN-1 (Compound 108) is an inhibitor of the POSH polypeptide （e3 ligase) and has antiviral, anticancer, and neurodegenerative disease potential.Fórmula:C14H8FNO3SPureza:99.29%Cor e Forma:SolidPeso molecular:289.28OS-2966
OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.Pureza:95%Cor e Forma:LiquidPeso molecular:~150 kDaMetribuzin
CAS:Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.
Fórmula:C8H14N4OSPureza:99.07%Cor e Forma:Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Peso molecular:214.29Alnuctamab
CAS:Alnuctamab (EM901) is a humanized, asymmetric two-arm IgG T-cell engager (TCE) with potential applications in immunological research [1].Cor e Forma:LiquidRovelizumab
CAS:Rovelizumab, Humanized anti-CD11/CD18 mAb, inhibits overactive leukocytes during shock, for MS, hemorrhagic shock, myocardial infarction, and stroke.Pureza:95% - 95%Cor e Forma:LiquidRinatabart
CAS:Rinatabart is a humanised monoclonal antibody targeting FRα/FOLR1, suitable for investigating ovarian and endometrial cancers expressing FRα.Pureza:95% - 95.7% (SDS-PAGE); 96.0% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.18 kDaVonsetamig
CAS:Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.Cor e Forma:LiquidLinvoseltamab
CAS:Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/Cor e Forma:LiquidPasotuxizumab
CAS:Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.Cor e Forma:LiquidObrindatamab
CAS:Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.Cor e Forma:LiquidCaplacizumab
CAS:Caplacizumab (ALX-0681), a humanized anti-von Willebrand factor (vWF) nanobody, serves to impede vWF-mediated platelet adhesion, thereby averting additionalCor e Forma:LiquidLocked nucleic acid 1
CAS:Locked nucleic acid 1 is an LNA-type nucleoside derivative.Fórmula:C32H32N2O8Pureza:98%Cor e Forma:SolidPeso molecular:572.61Anti-Mouse TCR γ/δ Antibody (UC7-13D5)
Anti-Mouse TCR gamma/delta Antibody is a host Armenian Hamster-derived IgG class inhibitor targeting the mouse TCR gamma/delta receptor.Cor e Forma:Odour LiquidEnlimomab
CAS:Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.Cor e Forma:LiquidVixtimotamab
Vixtimotamab (AMV-564; TandAb T564), a bispecific tetravalent tandem diabody (TandAb), selectively engages human CD33 and CD3 antigens.Cor e Forma:Odour LiquidFlotetuzumab
CAS:Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.Cor e Forma:LiquidDHX9-IN-8
CAS:DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].Fórmula:C18H16N2O3S2Cor e Forma:SolidPeso molecular:372.46Tepoditamab
CAS:Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.Cor e Forma:LiquidAnti-Mouse CD11b Antibody (M1/70)
The Anti-Mouse CD11b Antibody is a rat-derived IgG2b monoclonal antibody that targets the CD11b antigen on mouse cells.Cor e Forma:Odour LiquidPeso molecular:150 kDaViltolarsen
CAS:Viltolarsen targets exon 53 in the dystrophin gene for Duchenne muscular dystrophy research.Cor e Forma:SolidVatelizumab
CAS:Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.Pureza:95%Cor e Forma:LiquidPeso molecular:~150 kDaAnti-Mouse CD3ε Antibody (145-2C11)
Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activationPureza:99%Cor e Forma:Odour LiquidPeso molecular:150 kDa5-Methyl-5,6-dihydrouridine
CAS:5-Methyl-5,6-dihydrouridine is a minor constituent in the chromosomal RNA of the rat ascites tumor. It can be used for nucleic acid modification.Fórmula:C10H16N2O6Pureza:98%Cor e Forma:SolidPeso molecular:260.24Ubamatamab
CAS:Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].Pureza:95%Cor e Forma:LiquidVoxalatamab
CAS:Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].Cor e Forma:LiquidPavurutamab
CAS:Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.Cor e Forma:LiquidGSK4418959
CAS:GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.Fórmula:C31H30F4N4O5SPureza:99.141%Cor e Forma:SoildPeso molecular:646.65Vepsitamab
CAS:Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.Cor e Forma:LiquidIluzanebart
CAS:Iluzanebart, a hTREM2 agonist antibody, enhances microglial survival and function, modeling CSF1R-ALSP and microglial dysfunction in neurodegenerative studies.Pureza:95% - 97.7% (SDS-PAGE); 98.3% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:144.90 kDaAnti-Mouse CD32/CD16 Antibody (2.4G2)
Anti-Mouse CD32/CD16 Antibody is a rat-derived IgG2b inhibitor targeting the mouse CD32/CD16 antigens.Cor e Forma:Odour LiquidPeso molecular:150 kDaVVD-214
CAS:VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.Fórmula:C20H21F2N3O4SPureza:99.24% - 99.93%Cor e Forma:SoildPeso molecular:437.46Ref: TM-T85309
1mg69,00€5mg147,00€1mL*10mM (DMSO)164,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€Gresonitamab
CAS:Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.Cor e Forma:LiquidMirvetuximab soravtansine
CAS:Mirvetuximab soravtansine (IMGN853) is an antibody-drug coupling that targets FRα, inhibits cell growth, and can be used to study drug-resistant ovarian cancerPureza:6mg/ml - 95.52% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.76 kDa2'-Azido-2'-deoxyuridine
CAS:2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.Fórmula:C9H11N5O5Pureza:98%Cor e Forma:SolidPeso molecular:269.21L-Threonolactone
CAS:L-Threonolactone is a Carbohydrate Derivative.Fórmula:C4H6O4Cor e Forma:SolidPeso molecular:118.09SB273005
CAS:SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.Fórmula:C22H24F3N3O4Pureza:99.58%Cor e Forma:SolidPeso molecular:451.44Tilatamig samrotecan
Tilatamig samrotecan (AZD9592) is an antibody-drug conjugate (ADC) designed to deliver a topoisomerase I inhibitor (TOP1i). It targets epidermal growth factor receptor (EGFR) and c-MET and demonstrates antitumor activity. The compound induces DNA double-strand breaks, elevates pRAD50 and γH2AX expression, and inhibits the growth of non-small cell lung cancer.Cor e Forma:Odour SolidhDHODH-IN-2
CAS:hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.Fórmula:C19H16N2O2Pureza:98%Cor e Forma:SolidPeso molecular:304.349MC-1-F2
CAS:MC-1-F2 is a direct FOXC2 inhibitor with anticancer activity and inhibits cancer stem cell (CSC) properties and can be used to study prostate cancer.Fórmula:C37H46N16O2Pureza:97.31% - 98.44%Cor e Forma:SolidPeso molecular:746.87Adenosine 2'-PEG-Biotin
CAS:Adenosine 2'-PEG-Biotin, a bioreagent derived from adenosine, modulates cellular signaling pathways by mimicking the action of endogenous adenosine and binding to its receptors. This compound is used in research related to bioprobes, biosensors, and diagnostic agents.Fórmula:C26H40N8O8SCor e Forma:SolidPeso molecular:624.71RI(dl)-2 TFA
CAS:RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Fórmula:C19H17N3Cor e Forma:SolidPeso molecular:287.36(R)-(+)-O-Demethylbuchenavianine
CAS:(R)-(+)-O-Demethylbuchenavianine is a cyclin-dependent kinase (CDK) inhibitor. It inhibits CDK1, CDK5, glycogen synthase kinase 3 (GSK3), cdc2-like kinase (CLK1), and dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) with IC50 values of 1.1 μM, 0.95 μM, >10 μM, >10 μM, and >10 μM, respectively.Fórmula:C21H21NO4Cor e Forma:SolidPeso molecular:351.40E-982
CAS:E-982 is derived from the reference compound.Fórmula:C25H31NO6SPureza:98%Cor e Forma:SolidPeso molecular:473.58Tirofiban
CAS:Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.Fórmula:C22H36N2O5SPureza:99.83%Cor e Forma:SolidPeso molecular:440.6XL413
CAS:XL-413 is an oral CDC7 kinase inhibitor, potentially blocking DNA replication, mitosis, and cancer cell growth.Fórmula:C14H12ClN3O2Pureza:98.40% - 99.94%Cor e Forma:SolidPeso molecular:289.72BAY1217389
CAS:BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).Fórmula:C27H24F5N5O3Pureza:98.14% - 99.42%Cor e Forma:SolidPeso molecular:561.53,4-Dihydroxybenzylamine hydrobromide
CAS:3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.Fórmula:C7H10BrNO2Pureza:98.49%Cor e Forma:Light Beige Crystalline PowderPeso molecular:220.06GW843682X
CAS:GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).Fórmula:C22H18F3N3O4SPureza:99.92%Cor e Forma:SolidPeso molecular:477.46Mps1-IN-1
CAS:Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )Fórmula:C28H33N5O4SPureza:99.55%Cor e Forma:SolidPeso molecular:535.66TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Fórmula:C26H25ClF3N5O3Pureza:99.73%Cor e Forma:SolidPeso molecular:547.96Ref: TM-T6039
1mg38,00€5mg80,00€1mL*10mM (DMSO)96,00€10mg120,00€25mg216,00€50mg354,00€100mg512,00€200mg727,00€BI-831266
CAS:BI-831266 is a potent and selective Aurora kinase B inhibitor.Fórmula:C27H38ClN7O2Cor e Forma:SolidPeso molecular:528.09CM03
CAS:CM03 is a cell-selective G-quadruplex ligand with anti-cancer activity, stabilizing G4 genes, useful in pancreatic cancer research.Fórmula:C34H44N6O6Pureza:98.65%Cor e Forma:SolidPeso molecular:632.75Werner syndrome RecQ helicase-IN-4
CAS:Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.Fórmula:C32H33F3N8O5Pureza:98.27%Cor e Forma:SolidPeso molecular:666.655-Aminouridine
CAS:5-Aminouridine (4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)) modifies nucleobases and is incorporated into the target DNA.Fórmula:C9H13N3O6Pureza:99.53%Cor e Forma:SolidPeso molecular:259.22NSC666715
CAS:NSC666715 is the strand-displacement activity of DNA polymerase inhibitor.Fórmula:C15H13Cl2N5O2S2Pureza:98%Cor e Forma:SolidPeso molecular:430.33Zaurategrast ethyl ester sulfate
CAS:Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.Fórmula:C56H60Br2N8O10SPureza:98%Cor e Forma:SolidPeso molecular:1197.01TH470
CAS:TH470, a potent and highly selective inhibitor of LIM kinase 1/2 (LIMK1/2), demonstrates specificity with IC50 values of 9.8 nM for LIMK1 and 13 nM for LIMK2,Fórmula:C30H31N5O5S2Cor e Forma:SolidPeso molecular:605.73NSC 693868
CAS:CDKs and GSK-3 inhibitorFórmula:C9H7N5Pureza:98%Cor e Forma:SolidPeso molecular:185.19Y-9738
CAS:Y-9738 is an agent of hypolipidemic.Fórmula:C15H16ClNO4Pureza:98%Cor e Forma:SolidPeso molecular:309.74Balamapimod
CAS:Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.Fórmula:C30H32ClN7OSPureza:98%Cor e Forma:SolidPeso molecular:574.14cp028
CAS:cp028 inhibits pre-mRNA splicing in vitro.Fórmula:C23H17FN2O4Cor e Forma:SolidPeso molecular:404.39Aurora kinase inhibitor-10
CAS:Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.Fórmula:C21H19F5N6O4SCor e Forma:SolidPeso molecular:546.47Dyrk1A-IN-5
CAS:Potent DYRK1A inhibitor with IC50s: 6 nM overall, 0.5 μM SF3B1, 2.1 μM tau phosphorylation. Useful for Down syndrome studies.Fórmula:C16H9IN2O2Cor e Forma:SolidPeso molecular:388.16Crozbaciclib fumarate
CAS:Crozbaciclib fumarate is a CDK4/6 inhibitor with IC 50 s of 3 and 1 nM, respectively.Fórmula:C32H34F2N6O4Cor e Forma:SolidPeso molecular:604.65αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).Fórmula:C28H35F3N6O8SPureza:98%Cor e Forma:SolidPeso molecular:672.67Flurocitabine
CAS:Flurocitabine is a therapeutic agent with antineoplastic activity.Fórmula:C9H10FN3O4Pureza:98%Cor e Forma:SolidPeso molecular:243.19CRT-0105446
CAS:CRT-0105446 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.Fórmula:C20H18F3N3O2SPureza:98%Cor e Forma:SolidPeso molecular:421.44
