Ciclo celular/Ponto de verificação
Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Ciclo celular/Ponto de verificação"
- Aurora Quinase(116 produtos)
- CDK(548 produtos)
- Ciclo celular/Parada(5 produtos)
- Chk(49 produtos)
- DYRK(46 produtos)
- Dinamina(27 produtos)
- Ferroptose(233 produtos)
- HSP(180 produtos)
- Integrinas(276 produtos)
- Cinesina(87 produtos)
- LIM Quinase(21 produtos)
- Microtúbulo associado(273 produtos)
- PKC(128 produtos)
- PLK(25 produtos)
- ROCK(61 produtos)
- Rho(6 produtos)
- Wee1(14 produtos)
- c-Myc(77 produtos)
Exibir 10 mais subcategorias
Foram encontrados 3936 produtos de "Ciclo celular/Ponto de verificação"
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M443
CAS:M443 is a potent small molecule inhibitor of MRK that inhibits radiation-induced activation of p38 and Chk2 and can be used in cancer research.Fórmula:C31H30F3N7O2Pureza:98.95%Cor e Forma:SolidPeso molecular:589.61Aurora kinase inhibitor-10
CAS:Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.Fórmula:C21H19F5N6O4SCor e Forma:SolidPeso molecular:546.47CDK2-IN-12
CAS:CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.Fórmula:C20H17N9O2SCor e Forma:SolidPeso molecular:447.47Type II topoisomerase inhibitor 1
CAS:Potent E. coli DNA gyrase inhibitor (IC50: 1.7 nM), targets Asp73; weak topoisomerase IV inhibitor (IC50: 0.98 μM).Fórmula:C18H15N3O4Cor e Forma:SolidPeso molecular:337.33Ulecaciclib
CAS:Ulecaciclib: oral, BBB-permeable CDK inhibitor; favorable pharmacokinetics; ki: 0.62 μM (CDK2/A), 3 nM (CDK6/D3), 0.2 nM (CDK4/D1), 0.63 μM (CDK7/H).Fórmula:C25H33FN8SCor e Forma:SolidPeso molecular:496.65CAY10746
CAS:CAY10746 selectively inhibits ROCK I/II with IC50s: 0.014/0.003 μM, useful for diabetic retinopathy research.Fórmula:C26H23N3O5Pureza:99.71%Cor e Forma:SolidPeso molecular:457.48Ref: TM-T36196
2mg34,00€5mg54,00€1mL*10mM (DMSO)54,00€10mg86,00€25mg172,00€50mg260,00€100mg411,00€200mg552,00€MS0017509
CAS:MS0017509 is a DNA damage repair inhibitor.Fórmula:C11H10N4Pureza:98%Cor e Forma:SolidPeso molecular:198.22Carbonic anhydrase inhibitor 14
CAS:CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.Fórmula:C18H17N7O2SCor e Forma:SolidPeso molecular:395.44cp028
CAS:cp028 inhibits pre-mRNA splicing in vitro.Fórmula:C23H17FN2O4Cor e Forma:SolidPeso molecular:404.39CDK7-IN-2
CAS:CDK7-IN-2 inhibits CDK7, essential for RNA polymerase II activation and cell cycle control, with cancer research potential.Fórmula:C26H39N7O3Cor e Forma:SolidPeso molecular:497.63Cdc7-IN-13
CAS:Cdc7-IN-13 (compound 84) is a highly potent CDC7 inhibitor, exhibiting an IC50 value of <1 nM. This compound holds promise for cancer research [1].Fórmula:C18H20N4O2SCor e Forma:SolidPeso molecular:356.44CDK7-IN-8
CAS:CDK7-IN-8 is a potent inhibitor of CDK7 (IC50: 54.29 nM) and exhibits inhibitory activity against several cancer cells and in vivo tumor models.Fórmula:C25H38N8O3Cor e Forma:SolidPeso molecular:498.62VRX-0466617
CAS:VRX-0466617 is a novel selective Chk2 inhibitor.Fórmula:C19H20BrN5O2SCor e Forma:SolidPeso molecular:462.36OM-137
CAS:OM137 inhibits Aurora kinases, impedes cell growth at high doses, and enhances low-dose paclitaxel effects.Fórmula:C13H14N4O3SCor e Forma:SolidPeso molecular:306.34DHODH-IN-20
CAS:Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.Fórmula:C24H25F4N3O3Cor e Forma:SolidPeso molecular:479.47IRE1α kinase-IN-7
CAS:IRE1α kinase-IN-7 is a chemical compound functioning as an inhibitor of IRE1α kinase, primarily utilized in the research of diseases related to endoplasmicFórmula:C28H25F3N6OCor e Forma:SolidPeso molecular:518.53Balamapimod
CAS:Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.Fórmula:C30H32ClN7OSPureza:98%Cor e Forma:SolidPeso molecular:574.14Y-9738
CAS:Y-9738 is an agent of hypolipidemic.Fórmula:C15H16ClNO4Pureza:98%Cor e Forma:SolidPeso molecular:309.74BAY-707
CAS:BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.Fórmula:C15H20N4O2Pureza:98%Cor e Forma:SolidPeso molecular:288.34Atuveciclib S-Enantiomer
CAS:Atuveciclib S-Enantiomer is a (S)-form of BAY-1143572; a potent, selective CDK9 inhibitor with an IC50 of 16 nM.Fórmula:C18H18FN5O2SPureza:98%Cor e Forma:SolidPeso molecular:387.43DHODH-IN-19
CAS:DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)Fórmula:C22H18ClF6N3O3Cor e Forma:SolidPeso molecular:521.84Cdc7-IN-14
CAS:Cdc7-IN-14 (compound 82) is a potent CDC7 inhibitor with an IC50 < 1 nM, promising for cancer research.Fórmula:C18H20N4O2SCor e Forma:SolidPeso molecular:356.44Rho-Kinase-IN-2
CAS:Rho-Kinase-IN-2, an oral ROCK inhibitor (IC50=3nM), penetrates the CNS; potential in Huntington's research.Fórmula:C20H25FN4O2Cor e Forma:SolidPeso molecular:372.44ML372
CAS:ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.Fórmula:C18H20N2O4SCor e Forma:SolidPeso molecular:360.43RK-9123016
CAS:RK-9123016 is a SIRT2 inhibitor.
Fórmula:C16H18N6O3SPureza:99.65%Cor e Forma:SolidPeso molecular:374.422'-Fluorothymidine
CAS:2'-Fluorothymidine is a selective substrate for TK2, related to thymidine and methyluridine.Fórmula:C10H13FN2O5Pureza:99.98%Cor e Forma:SolidPeso molecular:260.22Ref: TM-T19101
1mg50,00€1mL*10mM (DMSO)101,00€5mg105,00€10mg161,00€25mg276,00€50mg416,00€100mg625,00€200mg837,00€MFH290
CAS:MFH290 is a selective CDK12/13 inhibitor, covalently bonding with CDK12 Cys-1039, blocks Pol II CTD phosphorylation, and enhances olaparib's efficacy.Fórmula:C26H31N5O3S2Cor e Forma:SolidPeso molecular:525.69Aurora A/PKC-IN-1
CAS:Aurora A/PKC-IN-1 inhibits AurA (IC50: 6.9 nM), PKCα (IC50: 16.9 nM), and hinders breast cancer cell growth and spread.Fórmula:C16H14N6OSe2Cor e Forma:SolidPeso molecular:464.24NSC 693868
CAS:CDKs and GSK-3 inhibitorFórmula:C9H7N5Pureza:98%Cor e Forma:SolidPeso molecular:185.19DAP-81
CAS:DAP-81, a diaminopyrimidine, inhibits Plk1 (IC50: 0.9 nM), disrupts microtubules, causes monopolar spindles; in preclinical studies.Fórmula:C25H20N6O4Cor e Forma:SolidPeso molecular:468.46CDK4/6-IN-9
CAS:CDK4/6-IN-9 selectively inhibits CDK4/6 (IC50: 905 nM); potential for MM research.Fórmula:C22H23FN8Cor e Forma:SolidPeso molecular:418.47A 65281
CAS:A 65281: antibacterial isothiazoloquinolone, inhibits P4-unknotting, induces DNA breakage via topoisomerase II.Fórmula:C17H16F2N4O2SPureza:98%Cor e Forma:SolidPeso molecular:378.4HBV-IN-16
CAS:HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).Fórmula:C22H20ClNO4Cor e Forma:SolidPeso molecular:397.85Mps1-IN-4
CAS:Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.Fórmula:C26H31F3N6O2Cor e Forma:SolidPeso molecular:516.56CLT-28643
CAS:CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.Fórmula:C19H17N3O4Pureza:99.89%Cor e Forma:SolidPeso molecular:351.36SB-772077B dihydrochloride
CAS:SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward ROCK1 and ROCK2, respectively).Fórmula:C15H20Cl2N8O2Pureza:98%Cor e Forma:SolidPeso molecular:415.28CDK7-IN-12
CAS:CDK7-IN-12 inhibits CDK7 to control transcription and cell cycle, halting tumor growth in vitro/vivo with cancer research potential.Fórmula:C20H19F3N6Cor e Forma:SolidPeso molecular:400.4BMH-23
CAS:BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.Fórmula:C15H15N3Pureza:98%Cor e Forma:SolidPeso molecular:237.3PFM03
CAS:PFM03 is a endonuclease inhibitor that specifically blocks Mre11,reduce MRN endonuclease activity, blocking hMRN-mediated endonucleotomy and nuclear exocytosis.Fórmula:C14H15NO2S2Pureza:99.81% - 99.98%Cor e Forma:SolidPeso molecular:293.4H-1152
CAS:H-1152 is a potent, specific, ATP-competitive, and cell permeable ROCK inhibitor (Ki = 1.6 nM).Fórmula:C16H21N3O2SPureza:98%Cor e Forma:SolidPeso molecular:319.42Crisnatol mesylate
CAS:Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.Fórmula:C24H27NO5SCor e Forma:SolidPeso molecular:441.54Lysine-methotrexate
CAS:Lysine-methotrexate is an anticancer drug. It is an inhibitor of dihydrofolate reductase.Fórmula:C21H27N9O3Pureza:98%Cor e Forma:SolidPeso molecular:453.5JFN05510
CAS:Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.Fórmula:C50H68N7O9PSiCor e Forma:SolidPeso molecular:970.18DHODH-IN-13
CAS:DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.Fórmula:C10H6F3N3O3Pureza:99.66%Cor e Forma:SolidPeso molecular:273.17TH470
CAS:TH470, a potent and highly selective inhibitor of LIM kinase 1/2 (LIMK1/2), demonstrates specificity with IC50 values of 9.8 nM for LIMK1 and 13 nM for LIMK2,Fórmula:C30H31N5O5S2Cor e Forma:SolidPeso molecular:605.73CCT068127
CAS:CCT068127 is a potent CDK2 and CDK9 inhibitor.Fórmula:C19H27N7OCor e Forma:SolidPeso molecular:369.46Zaurategrast ethyl ester sulfate
CAS:Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.Fórmula:C56H60Br2N8O10SPureza:98%Cor e Forma:SolidPeso molecular:1197.01Edatrexate
CAS:Edatrexate (CGP 30694), a Methotrexate analog, combats MTX-resistant tumors and researches various cancers.Fórmula:C22H25N7O5Cor e Forma:SolidPeso molecular:467.48FINDY
CAS:FINDY selectively inhibits DYRK1A at 35 μM IC50, blocking Ser97 autophosphorylation, useful for neurological disorder research.Fórmula:C16H17NO2S2SiCor e Forma:SolidPeso molecular:347.53DHODH-IN-8
CAS:DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).Fórmula:C17H13ClN2O2Pureza:99.78%Cor e Forma:SolidPeso molecular:312.75Ref: TM-T11030
500mgA consultar1mg109,00€2mg163,00€1mL*10mM (DMSO)235,00€5mg241,00€10mg354,00€25mg532,00€50mg745,00€100mg1.018,00€Picoplatin
CAS:Picoplatin, an anti-cancer agent overcoming platinum resistance, alkylates DNA to block replication, transcription, and induce apoptosis.Fórmula:C6H10Cl2N2PtPureza:98%Cor e Forma:SolidPeso molecular:376.14Werner syndrome RecQ helicase-IN-3
CAS:Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.Fórmula:C31H30ClF3N8O5Cor e Forma:SolidPeso molecular:687.07BDM44768
CAS:BDM44768 is an insulin-degrading enzyme (IDE) inhibitor that acts by inducing glucose intolerance.Fórmula:C24H22FN5O3Cor e Forma:SolidPeso molecular:447.46Scaff10-8
CAS:Scaff10-8 blocks AKAP-Lbc-RhoA, aiding aquaporin-2 movement in kidney cells.Fórmula:C22H18O6Pureza:98%Cor e Forma:SolidPeso molecular:378.37D-Xylofuranose, 1,2,3,5-tetraacetate
CAS:1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a starting material for the synthesis of nucleosides.Fórmula:C13H18O9Cor e Forma:SolidPeso molecular:318.28Mps-BAY2b
CAS:Mps-BAY2b is a novel MPS1 inhibitor.Fórmula:C20H23N5OCor e Forma:SolidPeso molecular:349.43Indirubin-5-sulfonate
CAS:Indirubin-5-sulfonate inhibits GSK-3β & CDKs with IC50: 55/35/150/300/65 nM for CDK1/B, 2/A&E, 4/D1, 5/p35.Fórmula:C16H10N2O5SPureza:98%Cor e Forma:SolidPeso molecular:342.33CB10-277
CAS:CB10-277 is a synthetic anti-cancer drug related to dacarbazine that alkylates DNA, inhibits DNA replication and repair, and may block DNA synthesis.Fórmula:C9H11N3O2Cor e Forma:SolidPeso molecular:193.214α-Demethylase/DNA Gyrase-IN-2
CAS:14α-Demethylase/DNA Gyrase-IN-2 (Compound 6a) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.Fórmula:C24H22N4O4Cor e Forma:SolidPeso molecular:430.46HHL-6
CAS:HHL-6 is a c-Fos and BDNF protein expression modulator.Fórmula:C19H26N2O3Cor e Forma:SolidPeso molecular:330.42Capzimin
CAS:Capzimin is a selective inhibitor of proteasome isopeptidase Rpn11.Fórmula:C30H24N6O2S4Pureza:98.31% - 99.32%Cor e Forma:SolidPeso molecular:628.81Ref: TM-T10672
2mgA consultar1mg48,00€5mg95,00€1mL*10mM (DMSO)131,00€10mg150,00€25mg300,00€50mg515,00€NSC666715
CAS:NSC666715 is the strand-displacement activity of DNA polymerase inhibitor.Fórmula:C15H13Cl2N5O2S2Pureza:98%Cor e Forma:SolidPeso molecular:430.33Binucleine 2
CAS:Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.Fórmula:C13H11ClFN5Cor e Forma:SolidPeso molecular:291.715-Aminouridine
CAS:5-Aminouridine (4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)) modifies nucleobases and is incorporated into the target DNA.Fórmula:C9H13N3O6Pureza:99.53%Cor e Forma:SolidPeso molecular:259.22DDD100097
CAS:DDD100097 is a N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders.Fórmula:C22H30Cl2F2N4O2SPureza:98.89%Cor e Forma:SolidPeso molecular:523.47Werner syndrome RecQ helicase-IN-4
CAS:Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.Fórmula:C32H33F3N8O5Pureza:98.27%Cor e Forma:SolidPeso molecular:666.65Tetrahydrouridine
CAS:Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.Fórmula:C9H16N2O6Pureza:98%Cor e Forma:SolidPeso molecular:248.23CM03
CAS:CM03 is a cell-selective G-quadruplex ligand with anti-cancer activity, stabilizing G4 genes, useful in pancreatic cancer research.Fórmula:C34H44N6O6Pureza:98.65%Cor e Forma:SolidPeso molecular:632.75NSC 109555 ditosylate
CAS:Chk2 inhibitor,ATP-competitiveFórmula:C26H32N10O4SPureza:98%Cor e Forma:SolidPeso molecular:580.66Metralindole HCl
CAS:Metralindole is a reversible monoamine oxidase A (RIMA) inhibitor, it was investigated as a potential antidepressant.Fórmula:C15H18ClN3OPureza:98%Cor e Forma:SolidPeso molecular:291.78BMS-587101
CAS:BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.Fórmula:C26H20Cl2N4O4SCor e Forma:SolidPeso molecular:555.43HR22C16
CAS:HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.Fórmula:C23H23N3O3Cor e Forma:SolidPeso molecular:389.455,10-Dideazaaminopterin
CAS:5,10-Dideazaaminopterin is an antileukemic drug.Fórmula:C21H22N6O5Pureza:98%Cor e Forma:SolidPeso molecular:438.44BSJ-01-175
CAS:BSJ-01-175: Selective, potent covalent inhibitor of CDK12/13, targets cancer cells, inhibits phosphorylated RNA polymerase II, downregulates CDK12 genes.Fórmula:C30H33ClN6O2Cor e Forma:SolidPeso molecular:545.08Metioprim
CAS:Metioprim is a competitive bacterial dihydrofolate reductases inhibitor.Fórmula:C14H18N4O2SPureza:98%Cor e Forma:SolidPeso molecular:306.38ERCC1-XPF-IN-1
CAS:ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.Fórmula:C28H32ClN5O2Cor e Forma:SolidPeso molecular:506.04Chlorozotocin
CAS:Chlorozotocin is a nitrosourea. It is used for cancer therapy.Fórmula:C9H16ClN3O7Cor e Forma:SolidPeso molecular:313.69Fozivudine tidoxil
CAS:Fozivudine tidoxil, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Fórmula:C35H64N5O8PSCor e Forma:SolidPeso molecular:745.95Aditoprime
CAS:Aditoprime (Aditoprim) is a selective bacterial DHFR inhibitor with strong nanomolar potency and broad-spectrum antibacterial activity.Fórmula:C15H21N5O2Pureza:99.89%Cor e Forma:SolidPeso molecular:303.36SR31527
CAS:SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Fórmula:C15H14ClN3OSPureza:98.52%Cor e Forma:SolidPeso molecular:319.81Ref: TM-T28848
1mg63,00€5mg137,00€1mL*10mM (DMSO)145,00€10mg215,00€25mg439,00€50mg708,00€100mg1.144,00€IS-741 calcium
CAS:IS-741 calcium is a phospholipase A2 inhibitor.Fórmula:C30H38CaF6N6O6S2Cor e Forma:SolidPeso molecular:796.86HBX28258
CAS:HBX28258, a human USP7 inhibitor, binds covalently and selectively deactivates USP7 in colon cancer and kidney cells.Fórmula:C26H30ClN3OPureza:98%Cor e Forma:SolidPeso molecular:435.99PF-2771
CAS:PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.Fórmula:C29H36ClN5O4Pureza:98%Cor e Forma:SolidPeso molecular:554.08JNJ-9676
CAS:JNJ-9676 is an orally active inhibitor of the coronavirus membrane protein, thereby blocking viral assembly and release.coronavirus and SARS-CoV.Fórmula:C28H21F2N5O2Pureza:99.83%Cor e Forma:SoildPeso molecular:497.5Ref: TM-T205924
1mg137,00€5mg330,00€1mL*10mM (DMSO)354,00€10mg532,00€25mg1.108,00€50mg1.738,00€100mg2.592,00€SR7826
CAS:SR7826 is a selective LIMK inhibitor.Fórmula:C22H21N5O2Pureza:98%Cor e Forma:SolidPeso molecular:387.43DHFR-IN-2
CAS:DHFR-IN-2 (4e) is a potent MtDHFR uncompetitive inhibitor with a 7 μM IC50, promising for TB research.Fórmula:C14H13NO2Cor e Forma:SolidPeso molecular:227.26Bis-Pro-5FU
CAS:Bis-Pro-5FU enhances oral uptake and safety of 5-FU, an anti-cancer drug for colorectal and pancreatic tumors.Fórmula:C10H7FN2O2Cor e Forma:SolidPeso molecular:206.17Antitumor agent-85
Antitumor agent-85 stabilizes G4-DNA with potent anti-tumor effects.Fórmula:C24H33N7Cor e Forma:SolidPeso molecular:419.57Aurora Kinases-IN-2
CAS:Aurora Kinases-IN-2 (12Aj) hinders Aurora A/B kinases (IC50: 90/152 nM), used in cancer studies.Fórmula:C22H18ClN5O3Cor e Forma:SolidPeso molecular:435.86L-Cytidine
CAS:L-Cytidine, pyrimidine nucleoside in RNA, regulates glial glutamate, brain lipids, catecholamines, and mitochondria.Fórmula:C9H13N3O5Cor e Forma:SolidPeso molecular:243.22CFI-400936
CAS:CFI-400936: potent TTK inhibitor (IC50=3.6nM), potential anticancer, active in cell assays, selective vs. human kinases.Fórmula:C25H27N5O3SCor e Forma:SolidPeso molecular:477.58CDK4/6-IN-12
CAS:CDK4/6-IN-12 inhibits CDK4/6 with IC50s of 592.3 nM & 3090 nM, useful in cancer research.Fórmula:C12H10N6Cor e Forma:SolidPeso molecular:238.25IS-741 potassium
CAS:IS-741 potassium is a phospholipase A2 inhibitor.Fórmula:C15H19F3KN3O3SCor e Forma:SolidPeso molecular:417.49Teloxantrone
CAS:Teloxantrone: an anthrapyrazole antibiotic inhibiting DNA replication, RNA/protein synthesis by interacting with DNA and topoisomerase II.Fórmula:C21H25N5O4Cor e Forma:SolidPeso molecular:411.45MSC-1186
CAS:MSC-1186 selectively inhibits SRPKs—IC50: 2.7nM (SRPK1), 81nM (SRPK2), 0.6nM (SRPK3)—for cancer research.Fórmula:C19H17ClFN7O2SCor e Forma:SolidPeso molecular:461.9VE-465
CAS:VE-465 is an inhibitor of Aurora kinase, which involves in multiple mitotic events.Fórmula:C22H28N8OSCor e Forma:SolidPeso molecular:452.58CAP-53194
CAS:CAP-53194 is a selective Plk1 inhibitor.Fórmula:C21H14N6O5Pureza:98%Cor e Forma:SolidPeso molecular:430.37SRPKIN-1
CAS:SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).Fórmula:C27H21FN2O3SPureza:98%Cor e Forma:SolidPeso molecular:472.53Levoleucovorin disodium
CAS:Levoleucovorin disodium is the sodium salt of the enantiomerically active form of Folinic Acid.Fórmula:C20H21N7Na2O7Pureza:98%Cor e Forma:SolidPeso molecular:517.41
