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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

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Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"

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  • (+)-Glaucarubinone
    Targetmol
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    (+)-Glaucarubinone

    <p>(+)-Glaucarubinone is a natural product that can be used as a reference standard.</p>
    Fórmula:C25H34O10
    Cor e Forma:Solid
    Peso molecular:494.537

    Ref: TM-T126136

  • Filanesib TFA
    Targetmol
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    Filanesib TFA

    CAS:
    <p>Filanesib (ARRY-520) inhibits KSP, triggering mitotic arrest and cell death in dividing tumor cells.</p>
    Fórmula:C22H23F5N4O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:534.5

    Ref: TM-T25418

  • WRN inhibitor 17
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    WRN inhibitor 17

    CAS:
    <p>WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.</p>
    Fórmula:C33H34F4N4O6S
    Cor e Forma:Solid
    Peso molecular:690.71

    Ref: TM-T203305

  • CCT241533 dihydrochloride
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    CCT241533 dihydrochloride

    CAS:
    <p>Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.</p>
    Fórmula:C23H29Cl2FN4O4
    Cor e Forma:Solid
    Peso molecular:515.41

    Ref: TM-T36704

  • Logotipo do CymitQuimica
    Targetmol
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    DSPE-PEG2000-cRGD

    <p>DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.</p>
    Cor e Forma:Odour Solid

    Ref: TM-TCL-01138

  • JH-XVI-178
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    JH-XVI-178

    CAS:
    <p>JH-XVI-178: potent CDK8/19 inhibitor with good pharmacokinetics, low clearance, moderate oral bioavailability.</p>
    Fórmula:C22H22ClN7O
    Cor e Forma:Solid
    Peso molecular:435.92

    Ref: TM-T40280

  • 5'-O-DMT-rU
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    5'-O-DMT-rU

    CAS:
    <p>5’-O-DMT-rU is a modified nucleoside and can be used to synthesize RNA.</p>
    Fórmula:C30H30N2O8
    Cor e Forma:Solid
    Peso molecular:546.57

    Ref: TM-T37141

  • Clofarabine-5'-triphosphate
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    Clofarabine-5'-triphosphate

    CAS:
    <p>Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.</p>
    Fórmula:C10H14ClFN5O12P3
    Cor e Forma:Solid
    Peso molecular:543.62

    Ref: TM-T203136

  • αVβ8-IN-1
    Targetmol
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    αVβ8-IN-1

    CAS:
    <p>αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).</p>
    Fórmula:C25H32ClN5O4
    Cor e Forma:Solid
    Peso molecular:502.01

    Ref: TM-T200044

  • Logotipo do CymitQuimica
    Targetmol
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    N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine

    <p>N4-Benzoyl-3'-O-DMT cytidine analog inhibits DNA methyltransferases like Zebularine.</p>
    Fórmula:C41H43N3O9
    Cor e Forma:Solid
    Peso molecular:721.79

    Ref: TM-T75224

  • Erythromycin thiocyanate
    Targetmol
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    Erythromycin thiocyanate

    CAS:
    <p>Erythromycin thiocyanate, a macrolide from Streptomyces erythreus, binds 50S ribosomes, halting protein synthesis in bacteria.</p>
    Fórmula:C38H68N2O13S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:793.02

    Ref: TM-T11233

  • HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt
    Targetmol
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    HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt

    CAS:
    <p>HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt inhibits pre-miR-21 RNA, potential for cancer research.</p>
    Fórmula:C57H62N8O10S
    Cor e Forma:Solid
    Peso molecular:1051.21

    Ref: TM-T74244

  • Logotipo do CymitQuimica
    Targetmol
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    5-Methylcytidine 5′-triphosphate trisodium

    <p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>
    Fórmula:C10H15N3Na3O14P3
    Cor e Forma:Solid
    Peso molecular:563.13

    Ref: TM-T74585

  • Logotipo do CymitQuimica
    Targetmol
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    3'-Deoxy-GTP trisodium

    <p>3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate) trisodium, an analog of GTP, functions as an RNA chain terminator, thereby inhibiting RNA synthesis. It is capable of suppressing dengue virus DENV NS5 RdRp with an IC50 value of 0.02 μM.</p>
    Cor e Forma:Odour Solid

    Ref: TM-T206808

  • Nusinersen
    Targetmol
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    Nusinersen

    CAS:
    <p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>
    Pureza:98.62%
    Cor e Forma:Solid

    Ref: TM-T38656

  • Logotipo do CymitQuimica
    Targetmol
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    N6-Methyl-2'-O-(2-methoxyethyl) adenosine

    <p>N6-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>
    Fórmula:C14H21N5O5
    Cor e Forma:Solid
    Peso molecular:339.35

    Ref: TM-T75062

  • Garenoxacin
    Targetmol
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    Garenoxacin

    CAS:
    <p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>
    Fórmula:C23H20F2N2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:426.41

    Ref: TM-T7179

  • HSDVHK-NH2
    Targetmol
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    HSDVHK-NH2

    CAS:
    <p>Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.</p>
    Fórmula:C30H48N12O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:720.78

    Ref: TM-TP1879

  • CDK5-IN-1
    Targetmol
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    CDK5-IN-1

    CAS:
    <p>CDK5-IN-1: Potent CDK5 inhibitor (&lt;10 nM) used in kidney disease research.</p>
    Fórmula:C24H25FN6O3S
    Cor e Forma:Solid
    Peso molecular:496.56

    Ref: TM-T40263

  • Heliquinomycin
    Targetmol
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    Heliquinomycin

    CAS:
    <p>Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.</p>
    Fórmula:C33H30O17
    Cor e Forma:Solid
    Peso molecular:698.586

    Ref: TM-T36748