CymitQuimica logo
Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

Exibir 10 mais subcategorias

Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • WRN inhibitor 17
    Targetmol
    + Info

    WRN inhibitor 17

    CAS:
    <p>WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.</p>
    Fórmula:C33H34F4N4O6S
    Cor e Forma:Solid
    Peso molecular:690.71

    Ref: TM-T203305

  • MRK-952
    Targetmol
    + Info

    MRK-952

    <p>MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.</p>
    Fórmula:C20H20ClF3N6
    Cor e Forma:Solid
    Peso molecular:436.861

    Ref: TM-T205743

  • Clofarabine-5'-diphosphate
    Targetmol
    + Info

    Clofarabine-5'-diphosphate

    CAS:
    <p>Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>
    Fórmula:C10H13ClFN5O9P2
    Cor e Forma:Solid
    Peso molecular:463.64

    Ref: TM-T203181

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    PROTAC MTP3 degrade-1

    <p>PROTACMTP3 degrade-1 is a PROTAC degrader for MYC.</p>
    Fórmula:C44H38N6O8
    Cor e Forma:Solid
    Peso molecular:778.27511

    Ref: TM-T207468

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    5-Methylcytidine 5′-triphosphate trisodium

    <p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>
    Fórmula:C10H15N3Na3O14P3
    Cor e Forma:Solid
    Peso molecular:563.13

    Ref: TM-T74585

  • Echistatin
    Targetmol
    + Info

    Echistatin

    CAS:
    <p>Potent αVβ3 integrin blocker, stops osteoclast binding &amp; bone loss, hinders platelet aggregation. Ki=0.27 nM, IC50s: 0.1 nM (bone), 30 nM (platelets).</p>
    Fórmula:C217H341N71O74S9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:5417.1

    Ref: TM-TP2098

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    AURKA against 1

    <p>Compound Ac13, also termed AURKA against 1, acts as an inhibitor of the Aurora kinase (AURKA) with an IC50 of less than 0.5 nM, targeting the acetylation of endogenous lysine (K162) and exhibiting anti-tumor cell proliferation activity. The kinase activity of AURKA, acetylated at K162 and induced by AURKA against 1, is reversibly restored in HCT116 cells transfected with SIRT3.</p>
    Fórmula:C28H32FN9O2
    Cor e Forma:Solid
    Peso molecular:545.61

    Ref: TM-T89903

  • 11H-Benzo[a]carbazole
    Targetmol
    + Info

    11H-Benzo[a]carbazole

    CAS:
    <p>11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.</p>
    Fórmula:C16H11N
    Pureza:99.14%
    Cor e Forma:Solid
    Peso molecular:217.27

    Ref: TM-TN9686

  • CTP Synthetase-IN-1 Ammonium salt
    Targetmol
    + Info

    CTP Synthetase-IN-1 Ammonium salt

    <p>CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infections</p>
    Fórmula:C20H22F3N7O3S2
    Pureza:99.97%
    Cor e Forma:Solid
    Peso molecular:529.56

    Ref: TM-T72505L

  • TAS-119
    Targetmol
    + Info

    TAS-119

    CAS:
    <p>TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95</p>
    Fórmula:C23H22Cl2FN5O3
    Pureza:99.65%
    Cor e Forma:Solid
    Peso molecular:506.36

    Ref: TM-T34787

  • Lorutengitide
    Targetmol
    + Info

    Lorutengitide

    CAS:
    <p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>
    Fórmula:C30H50N8O12
    Cor e Forma:Solid
    Peso molecular:714.764

    Ref: TM-TP3135

  • SMS 121
    Targetmol
    + Info

    SMS 121

    CAS:
    <p>SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.</p>
    Fórmula:C20H21NO5
    Pureza:98.29%
    Cor e Forma:Soild
    Peso molecular:355.38

    Ref: TM-T205876

  • WAY-647802
    Targetmol
    + Info

    WAY-647802

    CAS:
    <p>WAY-647802 is a CDK inhibitor.</p>
    Fórmula:C11H14N4O3
    Pureza:99.53%
    Cor e Forma:Solid
    Peso molecular:250.25

    Ref: TM-T9971

  • Carboxy pyridostatin trifluoroacetate salt
    Targetmol
    + Info

    Carboxy pyridostatin trifluoroacetate salt

    <p>Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.</p>
    Fórmula:C37H35F3N10O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:820.73

    Ref: TM-T13595

  • 5'-O-DMT-rI
    Targetmol
    + Info

    5'-O-DMT-rI

    CAS:
    <p>5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].</p>
    Fórmula:C31H30N4O7
    Cor e Forma:Solid
    Peso molecular:570.59

    Ref: TM-T37140

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    DHFR-IN-8

    <p>DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth.</p>
    Fórmula:C18H14N6S
    Cor e Forma:Solid
    Peso molecular:346.41

    Ref: TM-T79734

  • JAMM protein inhibitor 2 
    Targetmol
    + Info

    JAMM protein inhibitor 2 

    CAS:
    <p>JAMM inhibitor 2 targets thrombin, Rpn11, MMP2 with IC50s 10, 46, 89 μM, aids cancer research.</p>
    Fórmula:C21H26N2O2
    Pureza:98.57%
    Cor e Forma:Solid
    Peso molecular:338.44

    Ref: TM-T9892

  • CCT241533 dihydrochloride
    Targetmol
    + Info

    CCT241533 dihydrochloride

    CAS:
    <p>Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.</p>
    Fórmula:C23H29Cl2FN4O4
    Cor e Forma:Solid
    Peso molecular:515.41

    Ref: TM-T36704

  • SNX7
    Targetmol
    + Info

    SNX7

    CAS:
    <p>SNX7 (WAY-323879) inhibits CDKI pathway; useful for studying aging and related diseases.</p>
    Fórmula:C15H14N2O
    Pureza:99.05%
    Cor e Forma:Solid
    Peso molecular:238.28

    Ref: TM-T77613

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    wrwyar-NH2 TFA

    <p>wrwyar-NH2 (TFA) serves as the control peptide for wrwycr-NH2.</p>
    Cor e Forma:Odour Solid

    Ref: TM-TP3210