Dano de DNA/Reparo de DNA

Os inibidores de dano/ reparo do DNA são compostos que interferem nos processos envolvidos na detecção e reparo de danos ao DNA. Esses inibidores são fundamentais para estudar os mecanismos de estabilidade genômica, mutagênese e resposta ao dano ao DNA. Eles também são importantes na pesquisa do câncer, pois muitos tumores dependem de vias específicas de reparo de DNA para sobreviver. Ao inibir essas vias, os inibidores de dano/reparo de DNA podem aumentar a eficácia da quimioterapia e da radioterapia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade de dano/reparo de DNA para apoiar sua pesquisa em biologia molecular, oncologia e farmacologia.

Subcategorias de "Dano de DNA/Reparo de DNA"

Exibir 3 mais subcategorias

Foram encontrados 959 produtos de "Dano de DNA/Reparo de DNA"

Pureza (%)

100

produtos por página.

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Trovafloxacin
CAS:
- 147059-72-1
Trovafloxacin, a broad-spectrum quinolone antibiotic, exhibits potent activity against Gram-positive bacteria.
Fórmula:C₂₀H₁₅F₃N₄O₃
Pureza:99.21% - 99.27%
Cor e Forma:Solid
Peso molecular:416.35
Ref: TM-T13231
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Darglitazone Sodium
CAS:
- 149904-87-0
Darglitazone Sodium, an oral PPAR-γ agonist, aids type II diabetes study by regulating glucose and lipids.
Fórmula:C₂₃H₂₁N₂NaO₄S
Cor e Forma:Solid
Peso molecular:444.48
Ref: TM-T62576
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BGP-15
CAS:
- 66611-37-8
BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.
Fórmula:C₁₄H₂₄Cl₂N₄O₂
Pureza:98.17% - 99.89%
Cor e Forma:Solid
Peso molecular:351.27
Ref: TM-T3649
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Rucaparib Phosphate
CAS:
- 459868-92-9
Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.
Fórmula:C₁₉H₁₈FN₃O·H₃PO₄
Pureza:99.37%
Cor e Forma:Solid
Peso molecular:421.36
Ref: TM-T6127
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RHPS4
CAS:
- 390362-78-4
RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.
Fórmula:C₂₂H₁₇F₂N₂·CH₃O₄S
Pureza:99.72%
Cor e Forma:Solid
Peso molecular:458.48
Ref: TM-T6967
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Zebularine
CAS:
- 3690-10-6
Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.
Fórmula:C₉H₁₂N₂O₅
Pureza:99.04% - >99.99%
Cor e Forma:Solid
Peso molecular:228.2
Ref: TM-T2169
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Rabdosiin
CAS:
- 263397-69-9
Rabdosiin ((+)-Rabdosiin) is a natural product, and has anti-allergic activity, anti-HIV activity and inhibition on DNA topoisomerase.
Fórmula:C₃₆H₃₀O₁₆
Pureza:98.64% - 99.49%
Cor e Forma:Solid
Peso molecular:718.61
Ref: TM-T12651
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PIK-75 hydrochloride
CAS:
- 372196-77-5
PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.
Fórmula:C₁₆H₁₄BrN₅O₄S·HCl
Pureza:97.82%
Cor e Forma:Solid
Peso molecular:488.74
Ref: TM-T2287
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JW 55
CAS:
- 664993-53-7
JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2
Fórmula:C₂₅H₂₆N₂O₅
Pureza:99.31% - 99.76%
Cor e Forma:Solid
Peso molecular:434.48
Ref: TM-T1807
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Tretazicar
CAS:
- 21919-05-1
CB1954, an anticancer prodrug, turns into a potent alkylating agent when activated by NQO2 and EP-0152R.
Fórmula:C₉H₈N₄O₅
Pureza:99.41% - 99.7%
Cor e Forma:Solid
Peso molecular:252.18
Ref: TM-T6798
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Coralyne chloride
CAS:
- 38989-38-7
Coralyne chloride is a protoberberine with strong anticancer activity.
Fórmula:C₂₂H₂₂ClNO₄
Pureza:98.88%
Cor e Forma:Solid
Peso molecular:399.87
Ref: TM-T31011
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Remodelin hydrobromide
CAS:
- 1622921-15-6
Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
Fórmula:C₁₅H₁₅BrN₄S
Pureza:97.22% - 99.84%
Cor e Forma:Solid
Peso molecular:363.275
Ref: TM-T6133
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Clomesone
CAS:
- 88343-72-0
Clomesone, a synthetic drug, treats female infertility by blocking brain estrogen, inducing ovulation.
Fórmula:C₄H₉ClO₅S₂
Pureza:99%
Cor e Forma:Solid
Peso molecular:236.69
Ref: TM-T50086
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NPC 15199
CAS:
- 35661-60-0
NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.
Fórmula:C₂₁H₂₃NO₄
Pureza:99.93% - 99.94%
Cor e Forma:White Crystalline Powder
Peso molecular:353.41
Ref: TM-T8638
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Genz-644282
CAS:
- 529488-28-6
Genz-644282, a novel non-camptothecin topoisomerase I inhibitor for cancer treatment.
Fórmula:C₂₂H₂₁N₃O₅
Pureza:97.49%
Cor e Forma:Solid
Peso molecular:407.42
Ref: TM-T7187
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Pentamidine
CAS:
- 100-33-4
Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor
Fórmula:C₁₉H₂₄N₄O₂
Pureza:98.64% - 99.67%
Cor e Forma:Crystallizes As Colorless Plates From Water Solid
Peso molecular:340.42
Ref: TM-T23133
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Trifluridine/tipiracil hydrochloride mixture
CAS:
- 733030-01-8
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a
Fórmula:C₂₉H₃₄Cl₂F₆N₈O₁₂
Pureza:98% - 99.79%
Cor e Forma:Solid
Peso molecular:871.53
Ref: TM-T3658
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TIQ-A
CAS:
- 420849-22-5
TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.
Fórmula:C₁₁H₇NOS
Pureza:99.75%
Cor e Forma:Solid
Peso molecular:201.24
Ref: TM-T50098
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NU2058
CAS:
- 161058-83-9
NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.
Fórmula:C₁₂H₁₇N₅O
Pureza:99.34% - 99.92%
Cor e Forma:Solid
Peso molecular:247.3
Ref: TM-T3186
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AZD-2461
CAS:
- 1174043-16-3
AZD2461 is a novel PARP inhibitor.
Fórmula:C₂₂H₂₂FN₃O₃
Pureza:98% - 99.87%
Cor e Forma:Solid
Peso molecular:395.43
Ref: TM-T2484