Endocrinologia/Hormónios
Os inibidores de endocrinologia/hormônios são compostos que bloqueiam a ação dos hormônios ou interferem nas vias de sinalização hormonal. Esses inibidores são essenciais para estudar a regulação dos sistemas endócrinos e para desenvolver tratamentos para doenças relacionadas aos hormônios, como diabetes, distúrbios da tireoide e cânceres dependentes de hormônios. Ao modular a atividade hormonal, esses inibidores podem ajudar a elucidar as complexas interações dentro do sistema endócrino. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade para endocrinologia/hormônios para apoiar sua pesquisa em endocrinologia, farmacologia e ciências médicas.
Subcategorias de "Endocrinologia/Hormónios"
- Receptor de Androgénio(229 produtos)
- Anexina A(16 produtos)
- Aromatase(22 produtos)
- Receptor de estrogénio/progestagénio(60 produtos)
- GPR(1 produtos)
- Receptor de glicocorticoides(165 produtos)
- LHRH(2 produtos)
- Receptor opioide(325 produtos)
- Receptor de Prostaglandina(122 produtos)
- RAAS(90 produtos)
- Redutase(50 produtos)
- Somatostatina(57 produtos)
- Receptor de hormónio tireoidiano (THR)(32 produtos)
- Receptor de Vasopressina(48 produtos)
Exibir 6 mais subcategorias
Foram encontrados 3371 produtos de "Endocrinologia/Hormónios"
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Emd 52297
CAS:Emd 52297 is an inhibitor of renin.Fórmula:C39H59N11O7Pureza:98%Cor e Forma:SolidPeso molecular:793.96Galaxolide
CAS:Galaxolide can induce estrogenic activity (Estrogen Receptor/ERR), oxidative stress, and genotoxicity. It also stimulates the enzymatic activities of EROD and GST (Glutathione S-transferase).Fórmula:C18H26OCor e Forma:SolidPeso molecular:258.40LIT-001 free base
CAS:LIT-001, a nonpeptide OT-R agonist, enhances mouse autism-like behavior, with EC50=55 nM and Ki=226 nM.Fórmula:C28H33N7O2SPureza:98%Cor e Forma:SolidPeso molecular:531.67GLPG0492 (R enantiomer)
CAS:GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, a novel selective androgen receptor modulator.Fórmula:C19H14F3N3O3Cor e Forma:SolidPeso molecular:389.33Androgen receptor degrader-5
CAS:Androgen receptor degrader-5 (compound 14k) demonstrates superior capabilities, specifically in androgen receptor degradation and antiproliferative activity, showcasing its promising properties.Fórmula:C29H25F4N5O2Cor e Forma:SolidPeso molecular:551.53BMS-986034
CAS:BMS-986034 is a GPR119 agonist.Fórmula:C24H24Cl2N6O4Cor e Forma:SolidPeso molecular:531.39ADX61623
CAS:ADX61623 is an effective negative allosteric modulator (NAM) of the follicle-stimulating hormone receptor (FSHR). It also exhibits activity on the luteinizing hormone receptor (LH-R) but is inactive on the thyroid-stimulating hormone (TSH) receptor. ADX61623 can be utilized in research on estrogen-dependent diseases.Fórmula:C19H20N2O3Cor e Forma:SolidPeso molecular:324.375α-Tetrahydrocorticosterone
CAS:5α-Tetrahydrocorticosterone (5α-HB) is an endogenous steroid that acts as an agonist of the glucocorticoid receptor (GR) and a metabolite of corticosterone. It serves as an effective topical anti-inflammatory agent in vivo. In rat liver cells, it decreases the binding of metabolites to the glucocorticoid receptor-corticosterone and its 5α-reduced metabolites, with a Kd value of 268 nM. 5α-Tetrahydrocorticosterone is applicable in research on inflammatory skin diseases.Fórmula:C21H34O4Cor e Forma:SolidPeso molecular:350.49GC 14
CAS:GC 14 is a selective thyroid hormone receptor antagonist, with IC50 values of 200 nM and 35 nM for hTRα and hTRβ, respectively.Fórmula:C26H27NO6Pureza:98%Cor e Forma:SolidPeso molecular:449.5Sob-AM2
CAS:Sob-AM2 is an effective substrate targeting the fatty acid amide hydrolase (FAAH) expressed in the brain, with a Km of 1.3 μM. It delivers higher concentrations of Sobetirome to the central nervous system at minimal peripheral systemic doses, thereby activating the central thyroid hormone receptor β (TRβ).Fórmula:C21H27NO3Cor e Forma:SolidPeso molecular:341.44Novokinin
CAS:Angiotensin AT2 receptor agonistFórmula:C39H61N11O7Pureza:98%Cor e Forma:SolidPeso molecular:795.97FSH receptor antagonist 1
CAS:FSH receptor antagonist 1 (compound 10) is a potent antagonist of the G(s) protein-coupled human follicle-stimulating hormone (FSH) receptor. It exhibits an IC50 value of 28 nM in cell lines expressing the human FSH receptor. This compound significantly inhibits follicle growth and ovulation in in vitro mouse models.Fórmula:C33H32N2O2Cor e Forma:SolidPeso molecular:488.619Androgen receptor antagonist 13
CAS:Androgen receptor antagonist 13 (compound 8a) is an orally active androgen receptor antagonist with an IC50 of 0.20 μM. It is used in prostate cancer research.Fórmula:C16H15N3O3SCor e Forma:SolidPeso molecular:329.375′-Guanidinonaltrindole
CAS:5′-Guanidinonaltrindole (GNTI) is a selective antagonist of the kappa opioid receptor.Fórmula:C27H29N5O3Cor e Forma:SolidPeso molecular:471.551RJG-2051
CAS:RJG-2051 is a selective covalent inhibitor of aldo-keto reductase family 1 member C3 (AKR1C3), with an IC50 value of 13 nM. It interferes with the metabolism of substrates such as androgens, estrogens, and prostaglandins through AKR1C3. RJG-2051 holds potential for cancer research.Fórmula:C26H31N5O4SCor e Forma:SolidPeso molecular:509.62Ciprokiren
CAS:Ciprokiren, a renin inhibitor by Roche, halts human renin; IC50: 0.07/0.65 nmol/L. Lowers blood pressure in animals. Preclinical development ceased.Fórmula:C37H55N5O8SCor e Forma:SolidPeso molecular:729.93(E/Z)-OT-R antagonist 1
CAS:(E/Z)-OT-R antagonist 1 is a mixture of the E/Z configurations of OT-R antagonist 1. This compound is a novel, potent, selective, non-peptide OT-R antagonist that inhibits oxytocin-induced intracellular Ca2+ activity with an IC50 of 8 nM.Fórmula:C28H29N3O4Cor e Forma:SolidPeso molecular:471.55ZD 7155 hydrochloride
CAS:ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.Fórmula:C26H27ClN6OPureza:99.8%Cor e Forma:SolidPeso molecular:474.98Ref: TM-T13390
1mg42,00€5mg88,00€10mg135,00€25mg235,00€50mg396,00€100mg635,00€200mg887,00€1mL*10mM (DMSO)90,00€Cort108297
CAS:Cort108297: selective GR modulator/antagonist, high GR affinity (Ki: 0.45nM), no other steroid receptor affinity.Fórmula:C26H25F4N3O3SPureza:98.36% - 99.94%Cor e Forma:SolidPeso molecular:535.55Ref: TM-T15000
1mg274,00€5mg622,00€10mg908,00€25mg1.415,00€50mg1.882,00€100mg2.745,00€1mL*10mM (DMSO)747,00€L-371,257
CAS:L-371,257 is a competitive antagonist of oxytocin receptor with pA2 of 8.4 and Ki of 19 nM. L-371,257 shows a Ki of 3.7 nM for vasopressin receptor 1a.Fórmula:C28H33N3O6Pureza:99.79%Cor e Forma:SolidPeso molecular:507.58
