Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(63 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3054 produtos de "Imunologia e Inflamação"
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Reltecimod
CAS:Reltecimod, a CD28 antigen inhibitor, is used potentially for the treatment of necrotizing soft tissue infection.Fórmula:C46H72N10O15SPureza:98%Cor e Forma:SolidPeso molecular:1037.19Miptenalimab
CAS:<p>Miptenalimab (BI-754111) is an anti-human LAG-3 antibody with a dissociation constant (K D) of 88.6 nM for h LAG-3, effectively blocking the interaction between</p>Cor e Forma:LiquidSchisanchinin D
CAS:<p>Schisanchinin D is a useful organic compound for research related to life sciences. The catalog number is T125682 and the CAS number is 1614245-13-4.</p>Fórmula:C23H30O6Cor e Forma:SolidPeso molecular:402.487PMX 205
CAS:<p>PMX 205 is an effective complement antagonist of the C5a receptor.</p>Fórmula:C45H62N10O6Pureza:98%Cor e Forma:SolidPeso molecular:839.04Nemvaleukin alfa
CAS:<p>Nemvaleukin alfa (ALKS 4230) is an interleukin 2 fusion protein that is a selective agonist of the medium-affinity IL-2 receptor.</p>Pureza:98.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 98.4% (SDS-PAGE); 98.3% (SEC-HPLC)Cor e Forma:Liquid3-O-(2'E,4'Z-Decadienoyl)ingenol
<p>3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.</p>Fórmula:C30H42O6Cor e Forma:SolidPeso molecular:498.66cGAMP diammonium
<p>cGAMP is a second messenger that triggers interferon production via STING activation upon detecting cytosolic DNA.</p>Fórmula:C20H30N12O13P2Cor e Forma:SolidPeso molecular:708.47Clivatuzumab
CAS:<p>Clivatuzumab is a humanized anti-myxinomab, which can target the MUC1 epitope highly expressed on the surface of most pancreatic cancer cells, and has a good</p>Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Cor e Forma:LiquidPeso molecular:145.42 kDaTLQP-21
CAS:<p>TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.</p>Fórmula:C107H170N40O26Pureza:98%Cor e Forma:SolidPeso molecular:2432.75Eritoran
CAS:<p>Eritoran: TLR4 antagonist; shields mice from lethal influenza, EBOV, MARV; reduces granulocytosis, eases cytokine storm.</p>Fórmula:C66H126N2O19P2Cor e Forma:SolidPeso molecular:1313.66Biotin-labeled ODN 2395 sodium
<p>Biotin-labeled ODN 2395 (sodium), a Class C oligodeoxynucleotide and TLR9 agonist, serves to assess cellular uptake and localization of CpG ODN through a biotin</p>Cor e Forma:Odour SolidAra-F-NAD+
CAS:<p>Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.</p>Fórmula:C21H26FN7O13P2Cor e Forma:SolidPeso molecular:665.4213-(3-Methoxyphenyl)acrylic acid
CAS:<p>3-(3-Methoxyphenyl)acrylic acid can inhibit free radical generation, has antioxidant potential, and can be used in biochemical experiments and drug synthesis.</p>Fórmula:C10H10O3Pureza:99.91%Cor e Forma:SolidPeso molecular:178.19CP-289
CAS:<p>CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.</p>Fórmula:C30H35ClN2O2Pureza:99.97%Cor e Forma:SoildPeso molecular:491.06Antibacterial agent 273
<p>Antibacterialagent 273 (Compound 15e) is an antimicrobial agent targeting bacterial cell membranes, effectively disrupting them with a MIC value of 4 μg/mL against Staphylococcus aureus. It causes the leakage of intracellular nucleic acids and proteins, inhibits bacterial metabolic activity, and induces the accumulation of reactive oxygen species (ROS) within bacteria. Antibacterialagent 273 is applicable in research on infections caused by Staphylococcus aureus.</p>Cor e Forma:Odour SolidAntitumor agent-185
<p>Antitumor agent-185 (compound 3) exhibits significant antitumor effects, effectively inhibiting tumor growth and extending the survival period of mice in vivo.</p>Fórmula:C109H199N5O36P2Cor e Forma:SolidPeso molecular:2217.71ARC186
<p>ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.</p>Cor e Forma:SolidPeso molecular:120702.76TLR8 agonist 2
CAS:<p>TLR8 agonist 2 activates human TLR8 (EC50=3nM), less effective on TLR7 (EC50=33.33μM).</p>Fórmula:C16H22N8Cor e Forma:SolidPeso molecular:326.408FAPI-46
CAS:<p>FAPI-46 is a radiotracer for fibroblast activation protein (FAP),conjugated with 68Ga or 177Lu tracer for FAP tumours in positron emission tomography (PET).</p>Fórmula:C41H57F2N11O9Cor e Forma:SolidPeso molecular:885.96Keap1-Nrf2-IN-9
CAS:<p>Keap1-Nrf2-IN-9 inhibits Keap1-Nrf2 PPI with 0.575 µM IC50, boosts Nrf2 genes, non-toxic in ARPE19 cells.</p>Fórmula:C31H30N2O11S2Cor e Forma:SolidPeso molecular:670.71RDR03785
CAS:<p>The MIF Antagonist IV, RDR 03785 controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications.</p>Fórmula:C19H18F3NO4Pureza:98.92%Cor e Forma:SolidPeso molecular:381.3512-Oxo phytodienoic acid
CAS:<p>12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.</p>Fórmula:C18H28O3Pureza:98%Cor e Forma:SolidPeso molecular:292.41Anti-inflammatory agent 7
<p>Anti-inflammatory Agent 7 suppresses proinflammatory cytokines by hindering the NF-κB/MAPK signaling pathway in both LPS-treated RAW 264.7 cells and mice.</p>Fórmula:C36H40N4O9Cor e Forma:SolidPeso molecular:672.72Cartap hydrochloride
CAS:<p>Cartap hydrochloride is an insecticidal derivative. It is used to control chewing and sucking insects on many crops.</p>Fórmula:C18H33Cl2CuN3O3Cor e Forma:Colorless Crystalline Slightly Hygroscopic Solid CoaPeso molecular:473.93MTvkPABC-P5 TFA
<p>MTvkPABC-P5d TFA, a TLR7 agonist, functions as an immune stimulant. It is applicable in the synthesis of immune-stimulating antibody conjugates (ISAC).</p>Cor e Forma:Odour SolidGalectin-8-IN-2
CAS:<p>Galectin-8-IN-2 (Compound 10) acts as an inhibitor of galectin-8N [1].</p>Fórmula:C15H20O7Cor e Forma:SolidPeso molecular:312.32Chitohexaose hexahydrochloride
CAS:<p>Chitohexaose hexahydrochloride, a TLR4-inhibiting chitosan derivative, blocks LPS-induced inflammation.</p>Fórmula:C36H74Cl6N6O25Cor e Forma:SolidPeso molecular:1203.713-Methoxycatechol
CAS:<p>3-Methoxycatechol: lignin-based, esophageal carcinogen. 1,2-Dihydroxy-3-methoxybenzene: potent anti-EMCV.</p>Fórmula:C7H8O3Pureza:99.31%Cor e Forma:SolidPeso molecular:140.14N188 TFA
<p>N188 TFA is a radiolabeled ligand based on a bicyclic peptide scaffold, targeting the protein nectin-4, which is overexpressed in various tumors. It can be efficiently labeled with the radioactive isotope 68Ga to form 68Ga-N188, suitable for positron emission tomography (PET) imaging. The development of N188 TFA and its radiolabeled form, 68Ga-N188, holds potential for the diagnosis and treatment of cancers such as urothelial carcinoma.</p>Cor e Forma:Odour SolidAmfenac sodium
CAS:<p>Amfenac is a nonsteroidal anti-inflammatory drug. Amfenac also has acetic acid moiety.</p>Fórmula:C15H12NNaO3Pureza:98%Cor e Forma:SolidPeso molecular:277.26Isosorbide dinitrate
CAS:<p>Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.</p>Fórmula:C6H8N2O8Pureza:99.87%Cor e Forma:Hard Colorless Crystals SolidPeso molecular:236.14MC1
MC1, an effective NLRP3 inhibitor, exhibits a KD value of 19.3 nM and is devoid of cytotoxicity. This compound enhances cognitive function without causing adverse effects and exhibits no hepatotoxicity. MC1 holds potential for research in Alzheimer's disease.Fórmula:C23H23N3O6S2Cor e Forma:SolidPeso molecular:501.58Maritimetin
CAS:<p>Maritimein, an aurone from Coreopsis tinctoria, has potent antioxidant activity (IC50: 4.12 μM) and is used in cardiovascular research.</p>Fórmula:C15H10O6Cor e Forma:SolidPeso molecular:286.24NH2-UAMC1110 TFA
CAS:<p>NH2-UAMC1110 TFA, a derivative of the fibroblast activation protein (FAP) inhibitor UAMC1110, serves as a precursor in the formation of FAPI-QS, a chelating</p>Fórmula:C23H24F5N5O5Pureza:99.02%Cor e Forma:SolidPeso molecular:545.46TMV-IN-6
<p>TMV-IN-6 (Compound 4g) serves as a novel antiviral and fungicidal agent that impedes tobacco mosaic virus (TMV) assembly, functioning by attachment to TMV coat</p>Fórmula:C29H27N3OSCor e Forma:SolidPeso molecular:465.614-methyl-6-phenyl-2H-pyranone
CAS:<p>4-methyl-6-phenyl-2H-pyranone from Scutellaria boosts mitochondria, shields astrocytes from peroxide.</p>Fórmula:C12H10O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:186.21β-Amyrin acetate
CAS:<p>Beta-Amyrin acetate: HMGCR & sEH inhibitor (IC50 3.4 μM), anti-inflammatory, antifungal, antioxidant, anti-hyperlipidemic.</p>Fórmula:C32H52O2Pureza:99.87%Cor e Forma:SolidPeso molecular:468.75diABZI-C2-NH2
CAS:<p>diABZI-C2-NH2 is an agonist of the interferon gene STING, which modulates STING-dependent type I interferon production.</p>Fórmula:C36H43N13O4Pureza:96.09%Cor e Forma:SolidPeso molecular:721.81MC-ND-18
<p>MC-ND-18 is an ATTEC degrader that facilitates the degradation of NLRP3 via autophagy, exhibiting a DC50 of 125.5 nM in THP-1 cells. It is composed of an NLRP3 ligand, a linker, and an LC3 ligand.</p>Fórmula:C42H42Br2IN3O9SPeso molecular:1049.00532Damnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Fórmula:C16H12O5Cor e Forma:SolidPeso molecular:284.267Anti-inflammatory agent 78
<p>Anti-inflammatory agent 78 (compound L-37) is a potent anti-inflammatory agent. It effectively inhibits PGE2, PGE1, COX-2, and COX-1. Additionally, Anti-inflammatory agent 78 suppresses the release of NO in LPS-stimulated RAW 264.7 cell lines.</p>Fórmula:C19H14ClNO4Peso molecular:355.06114Dazostinag
CAS:<p>Dazostinag (TAK-676) is a STING agonist with anti-cancer properties, used in making ADCs.</p>Fórmula:C21H22F2N8O10P2S2Cor e Forma:SolidPeso molecular:710.52StemRegenin 1 Hydrochloride
CAS:<p>StemRegenin 1 Hydrochloride is an AhR antagonist (IC₅₀ = 127 nM) that inhibits RANKL-induced osteoclast generation and differentiation.</p>Fórmula:C24H24ClN5OSPureza:99.94%Cor e Forma:SolidPeso molecular:466Isorabaichromone
CAS:<p>Isorabaichromone exhibits potent antioxidative properties, including DPPH radical and superoxide anion scavenging activities [1].</p>Fórmula:C29H32O12Pureza:98%Cor e Forma:SolidPeso molecular:572.562-Hydroxybenzylamine
CAS:<p>2-Hydroxybenzylamine captures IsoLGs, prevents early atrial fibrillation recurrence post-ablation.</p>Fórmula:C7H9NOPureza:95.93%Cor e Forma:CoaPeso molecular:123.15BMS-986235
CAS:<p>BMS-986235 (LAR-1219), an oral FPR2 agonist, EC50: 0.41 nM (hFPR2), 3.4 nM (mFPR2), may prevent heart failure.</p>Fórmula:C18H17F2N3O3Pureza:99.85%Cor e Forma:SolidPeso molecular:361.34Efmarodocokin alfa
CAS:<p>Efmarodocokin alfa, IL-22/IgG4 fusion protein, activates IL-22 pathways, researched for severe COVID-19 pneumonia.</p>Cor e Forma:LiquidEfineptakin alfa
CAS:<p>Efineptakin alfa (NT-17), a recombinant IL-7, boosts CD4+ and CD8+ cell growth and is used in glioblastoma studies.</p>Cor e Forma:LiquidBiotin-labeled ODN 1826 sodium
<p>Biotin-labeled ODN 1826 (sodium), a class B CpG oligodeoxynucleotide (ODN), serves as a TLR9 agonist and facilitates assessment of CpG ODN cellular uptake and</p>Cor e Forma:Odour SolidD-NAME (hydrochloride)
CAS:<p>D-NAME, a less active NO synthase inhibitor enantiomer, has mild cardiovascular effects in rats; inactive in mouse nociception.</p>Fórmula:C7H16ClN5O4Cor e Forma:SolidPeso molecular:269.69Piperkadsin A
CAS:<p>Piperkadsin A effectively inhibits reactive oxygen species (ROS) production, specifically targeting PMA-induced ROS in human polymorphonuclear neutrophils,</p>Fórmula:C21H24O5Pureza:98%Cor e Forma:SolidPeso molecular:356.41MAPK-IN-4
<p>MAPK-IN-4 (Compound c1) is an orally active anti-inflammatory agent that inhibits the expression and release of pro-inflammatory cytokines IL-6 and TNF-α induced by LPS. It interacts with IRAK4 to exert its anti-inflammatory effects by inhibiting the MAPK pathway.</p>Cor e Forma:Odour SolidM133 peptide
<p>The M133 peptide is a coronavirus-specific CD4 T cell epitope. In mice infected with the neurotropic coronavirus (strain JHM of mouse hepatitis virus), the M133 peptide demonstrates immunodominance. It activates CD4 T cells by forming an MHC/peptide complex through binding with MHC II molecules, which is recognized by specific TCRs.</p>Fórmula:C84H130N20O25Peso molecular:1818.9516Dithianon
CAS:Dithianon: broad-spectrum anthraquinone fungicide; sticks to leaves/fruits; controls various fungi in some produce.Fórmula:C14H4N2O2S2Pureza:98%Cor e Forma:SolidPeso molecular:296.32CP-447697
CAS:CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.Fórmula:C29H26ClF2N3O2SPureza:99.90%Cor e Forma:SoildPeso molecular:554.05GB1908
<p>GB1908 is a selective oral inhibitor of galectin-1 (galectin-1), with Ki values of 57 nM for human galectin-1 and 72 nM for mouse galectin-1. It demonstrates over 50-fold selectivity for galectin-1 compared to galectin-3. GB1908 can be utilized in lung cancer research.</p>Fórmula:C18H18Cl2N4O5S2Peso molecular:504.00957SARS-CoV-2-IN-39
CAS:<p>SARS-CoV-2-IN-39 is a SARS-CoV-2 inhibitor with an EC50 of 1 μM.</p>Fórmula:C14H8ClF4NO3Pureza:99.86%Cor e Forma:SoildPeso molecular:349.66HSV-60mer sodium
<p>HSV-60mer sodium is a 60 bp double-stranded oligonucleotide that includes viral DNA motifs from the herpes simplex virus 1 (HSV-1) genome. Transfection of HSV-60mer effectively induces IFN-β in a manner dependent on STING, TBK1, and IFN regulatory factor 3 (IRF3).</p>JH-FK-08
<p>JH-FK-08 is an inhibitor of the serine/threonine-specific phosphatase enzyme calcineurin (calcium-dependent phosphatase). It demonstrates antifungal activity, effectively inhibiting C. neoformans with a MIC80 of 0.8 µg/mL. Additionally, JH-FK-08 exhibits immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM, and shows anti-infective activity in mouse models.</p>Fórmula:C45H73N3O13Cor e Forma:SolidPeso molecular:864.073Calcitriol Impurities D
CAS:<p>Calcitriol Impurities D: Vitamin hormone, promotes cell differentiation, has bone activity, inhibits HIV, and aids in treating AIDS/viral infections.</p>Fórmula:C28H46O3Pureza:98%Cor e Forma:SolidPeso molecular:430.66COX-2/NLRP3-IN-1
<p>COX-2/NLRP3-IN-1 (Compound 6k) is an inhibitor that targets COX-2 and NLRP3, exhibiting an IC50 value of 1.53 μM for COX-2. This compound exerts anti-inflammatory effects by inhibiting the NF-κB/NLRP3 signaling pathway.</p>Fórmula:C24H19Cl2N5OSPeso molecular:495.06874PROTAC IRAK4 degrader-11
PROTACIRAK4 degrader-11 (compound 15) is a PROTAC molecule utilizing a Cereblon ligand, achieving a maximal IRAK4 degradation rate of 96.25% in HEK293 cells, with a DC50 value of 2.29 nM.Fórmula:C41H41F3N8O6Peso molecular:798.31012Ezeprogind
CAS:<p>Ezeprogind, TLR9 inhibitor for Alzheimer's. Affordable Excellence: Reliable Quality You Can Trust</p>Fórmula:C25H44N6Pureza:99.28%Cor e Forma:SolidPeso molecular:428.66Glutaminase C-IN-2
<p>Glutaminase C-IN-2 (compound 11), an allosteric inhibitor of glutaminase C (GAC), exhibits potent inhibitory activity with an IC50 of 10.64 nM.</p>Fórmula:C24H23N7O2SPureza:98%Cor e Forma:SolidPeso molecular:473.55UNC9036
<p>UNC9036 is a PROTAC degrader of STING, with a DC50 value of 227 nM. The degradation of STING mediated by UNC9036 is dependent on the proteasomal VHL pathway.</p>Fórmula:C73H95N17O11SPeso molecular:1417.71177TBK1/IKKε-IN-6
CAS:<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Fórmula:C31H36F2N8O4Cor e Forma:SolidPeso molecular:622.678SARS-CoV-2 Mpro-IN-41
SARS-CoV-2 Mpro-IN-41 (Compound 7e) is an orally active inhibitor targeting COX-2 and SARS-CoV-2 Mpro, with respective IC50 values of 9.66 μM and 13.24 μM. It also demonstrates inhibitory activity against COX-1 (IC50: 46.11 μM). This compound significantly suppresses the expression of inflammation-related cytokines such as TNF-α, IL-6, and IL-1β, exhibiting anti-inflammatory properties. By selectively inhibiting COX-2 and SARS-CoV-2 Mpro, SARS-CoV-2 Mpro-IN-41 exerts both anti-inflammatory and antiviral effects, making it a potential candidate for research in inflammation and COVID-19 treatment.Fórmula:C27H23ClN4O3SCor e Forma:SolidPeso molecular:518.11794mPGES-1/5-LOX-IN-1
mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.Fórmula:C20H22N4O6SPeso molecular:446.126016Lac[6]Met
CAS:<p>6Lac[6]Met is a galectin-4 inhibitor with an IC50 value of 5 μM [1].</p>Fórmula:C126H180N12O66S6Cor e Forma:SolidPeso molecular:3111.21PROTAC IRAK4 degrader-5
CAS:<p>PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.</p>Fórmula:C41H40F3N11O9Cor e Forma:SolidPeso molecular:887.834Antibiofilm agent-8
<p>Antibiofilm agent-8 (compound Ru2) boosts antibacterial activity under visible light (400-700 nm, 10 J cm-2). It induces oxidative stress by promoting NADH oxidation and reactive oxygen species (ROS) generation, which disrupts the bacterial cell wall.</p>Fórmula:C35H23ClF6N7PRuPeso molecular:823.03887CAY10512
CAS:<p>CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.</p>Fórmula:C15H13FOCor e Forma:SolidPeso molecular:228.266Mipeginterferon alfa-2b
CAS:<p>Mipeginterferon alfa-2b, an IFNA2b analogue, has 5 modified amino groups out of 11 and weighs 40 kDa.</p>Cor e Forma:LiquiddsVACV-70mer sodium
<p>dsVACV-70mer sodium is a 70 base pair double-stranded oligonucleotide that contains a viral DNA motif derived from vaccinia virus DNA. It effectively induces IFN-β through a STING-dependent mechanism.</p>NLRP3-IN-52
NLRP3-IN-52 (compund 1) serves as an inhibitor of NLRP3.Fórmula:C19H25N5O3Cor e Forma:SolidPeso molecular:371.43STING agonist-31
CAS:<p>STING agonist-31, a potent STING agonist, exhibits EC50 values of 0.24 μM and 39.51 μM for human STING (h-STING) and murine STING (m-STING), respectively,</p>Fórmula:C43H51N15O6Cor e Forma:SolidPeso molecular:873.96Benz-AP
CAS:<p>Benz-AP: potent photosensitizer, creates singlet oxygen, more toxic in low hCES2 cancer cells, generates ROS via TPE to kill tumors.</p>Fórmula:C20H13NO2Cor e Forma:SolidPeso molecular:299.32OVA Peptide(257-264) acetate salt
<p>OVA Peptide(257-264) acetate salt is a Class I (Kb)-restricted epitope of OVA. This octamer peptide is presented by Class I MHC molecule H-2Kb derived from ovalbumin.</p>Fórmula:C47H78N10O15Peso molecular:1022.56481(-)-10,11-Dihydroxyfarnesol
CAS:<p>(-)-10,11-Dihydroxyfarnesol, from Cryptomarasmius aucubae, inhibits NO production.</p>Fórmula:C15H28O3Cor e Forma:SolidPeso molecular:256.38Suc-Tyr-Val-Ala-Asp-pNA
CAS:<p>Suc-YVAD-pNA, a chromogenic caspase-1 substrate.</p>Fórmula:C31H38N6O12Cor e Forma:SolidPeso molecular:686.675ZM640
ZM640 is an NLRP3 inhibitor that promotes IL-1β release mediated by NLRP3 inflammasome activation in THP-1 cells. It demonstrates low cytotoxicity.Fórmula:C28H36F3NO8SPeso molecular:603.21137WAY-605471
CAS:WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.Fórmula:C14H15NO3S2Pureza:99.62%Cor e Forma:SolidPeso molecular:309.4Siegesbeckialide I
<p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>Fórmula:C20H28O6Cor e Forma:SolidPeso molecular:364.43R-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Fórmula:C22H19N3O2S2Cor e Forma:SolidPeso molecular:421.54UNC8900
UNC8900 is a VHL-recruiting STINGPROTAC degrader with a DC50 of 0.924 μM. It is applicable for the study of bacterial and viral infections.Fórmula:C75H99N17O15SPeso molecular:1509.72273hSTING agonist-1
<p>hSTING agonist-1 (compound 17) is a potent activator of hSTING. It has poor oral bioavailability but plays a significant role in inflammation research.</p>Fórmula:C18H18F3N5O3SCor e Forma:SolidPeso molecular:441.427ODN D-SL03
CAS:<p>ODN D-SL03, a C class CpG oligonucleotide, stimulates PBMCs, activating B cells, NK cells & monocytes, and can inhibit tumor growth.</p>Cor e Forma:SolidPeso molecular:9345STING modulator-5
CAS:<p>STING modulator-5: pIC50 9.5, antagonizes PBMC (pIC50 8.1), THP-1 cell antagonist, for immunology research.</p>Fórmula:C43H45F4N11O5Cor e Forma:SolidPeso molecular:871.88EC1169
CAS:<p>EC1169 is a targeted PSMA ligand that acts to inhibit the proliferation of cells expressing PSMA.</p>Fórmula:C78H112N14O28S3Cor e Forma:SolidPeso molecular:1790.00Chitoheptaose heptahydrochloride
CAS:<p>Chitoheptaose heptahydrochloride, a chitosan derivative, enhances wheat growth and photosynthesis, with health-protective traits.</p>Fórmula:C42H80ClN7O29Cor e Forma:SolidPeso molecular:1182.57ROS-ERS inducer 1
<p>Type II ICD agent, ROS-ERS inducer 1, is a Pt(II)-NHC from 4,5-diarylimidazole, boosting ER stress, ROS, and DAMPs in HCC, outperforming Cisplatin.</p>Fórmula:C24H23F2I2N3PtCor e Forma:SolidPeso molecular:840.35cGAS-IN-3
<p>cGAS-IN-3 (compound 30d-S) is an orally active inhibitor of cyclic GMP-AMP synthase (cGAS) that exhibits excellent plasma exposure and low clearance rate. It demonstrates anti-inflammatory properties, significantly reducing pulmonary inflammation in rats.</p>Fórmula:C21H20Cl2F2N4O2Peso molecular:468.09314Porphyra 334
CAS:<p>Porphyra 334 is a mycosporine-like amino acid.</p>Fórmula:C14H22N2O8Cor e Forma:SolidPeso molecular:346.336Human Immunoglobulin M
<p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>Cor e Forma:Odour SolidEnglumafusp alfa
<p>Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion protein combining a CD19-specific antibody domain with trimerized extracellular domains of human 4-1BBL,</p>Cor e Forma:Odour LiquidMitoquinol
CAS:<p>Mitoquinol is a mitochondria-targeted antioxidant used in the study of cardiovascular disease by modulating the mitochondrial antioxidant defense system.</p>Fórmula:C38H49O7PSPureza:98%Cor e Forma:SolidPeso molecular:680.83(±)-Phrymarolin II
CAS:<p>(±)-Phrymarolin II is a promising class of inhibitors that targets the tobacco mosaic virus, representing a novel approach in plant virus suppression.</p>Fórmula:C23H22O10Cor e Forma:SolidPeso molecular:458.419Biotin-labeled ODN 1668 sodium
<p>Biotin-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN) and TLR9 agonist, facilitates the assessment of cellular uptake and localization of</p>Cor e Forma:Odour SolidMCC950
CAS:<p>MCC950 (CP-456773) is a NLRP3 inflammasome inhibitor (IC50=7.5-8.1 nM). MCC950 can be used to treat inflammatory diseases. High-Quality, Low-Cost!</p>Fórmula:C20H24N2O5SPureza:97% - 98%Cor e Forma:SolidPeso molecular:404.48NLRP3-IN-68
<p>NLRP3-IN-68 (Compound 2d) is a derivative of 1,3,4-oxadiazole. It exhibits significant anti-inflammatory and antioxidant properties, effectively inhibiting the secretion of inflammatory cytokines, the expression of iNOS, and the activation of the NLRP3 inflammasome. NLRP3-IN-68 is applicable in the research of anti-inflammatory drugs.</p>Fórmula:C18H15FN2O3Cor e Forma:SolidPeso molecular:326.322
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