Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(148 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(60 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(444 produtos)
- NOD(17 produtos)
- NOS(63 produtos)
- Nrf2(79 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3045 produtos de "Imunologia e Inflamação"
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NLRP3-IN-50
<p>NLRP3-IN-50 (compound SN3-1) is a potential inhibitor of NLRP3, offering therapeutic promise for inflammatory diseases.</p>Fórmula:C23H22Cl2N2O4S2Cor e Forma:SolidPeso molecular:525.47GHN105
<p>GHN105 is an orally active STING inhibitor that suppresses STING-dependent IFN-β secretion in THP-1 human monocytes with an IC50 of 4.4 μM. In mice, GHN105 reduces serum levels of IFN-β, IL-6, and CXCL10, and alleviates colitis in a DSS-induced acute colitis mouse model. Additionally, GHN105 demonstrates favorable pharmacokinetic properties in mice, with an oral bioavailability of 43% and a half-life of 1.1 hours.</p>Fórmula:C41H56N2O14Cor e Forma:SolidPeso molecular:800.89Inflexuside A
CAS:<p>Inflexuside A, an abietane diterpenoid from Isodon inflexus, and Inflexuside B inhibit NO in LPS-stimulated RAW264.7 cells.</p>Fórmula:C26H42O9Cor e Forma:SolidPeso molecular:498.61Prifelone
CAS:<p>Prifelone (R 830) is a non-steroidal anti-inflammatory compound with antioxidant activity.</p>Fórmula:C19H24O2SPureza:99.8%Cor e Forma:SolidPeso molecular:316.46Dibenzothiophene
CAS:<p>Dibenzothiophene, a sulfur PAH in petroleum, has 3 rings and keratolytic properties.</p>Fórmula:C12H8SPureza:99.82%Cor e Forma:Yellow To Green SolidPeso molecular:184.26RH-EDA
<p>RH-EDA, a rhodamine-based turn-on fluorescent probe, detects hydroxyl radicals ([OH]) in living systems.</p>Fórmula:C28H25N3O4Cor e Forma:SolidPeso molecular:467.52MC4762
<p>MC4762 is an inhibitor of NOX2 and MAOB, with IC50 values of 0.155 μM and 0.182 μM, respectively. It exhibits anti-inflammatory properties by suppressing the production of ROS and downregulating the expression of pro-inflammatory cytokines such as iNOS, IL-1β, and IL-6.</p>Cor e Forma:Odour SolidSuc-Tyr-Val-Ala-Asp-pNA
CAS:<p>Suc-YVAD-pNA, a chromogenic caspase-1 substrate.</p>Fórmula:C31H38N6O12Cor e Forma:SolidPeso molecular:686.675Perfluorohexane
CAS:<p>Perfluorohexane (AF-0150) is a perfluorocarbon (PFC)-based microbubble formulation for ultrasound contrast and is developmentally toxic.</p>Fórmula:C6F14Pureza:98%Cor e Forma:Colourless LiquidPeso molecular:338.04NOD2 agonist 2
<p>NOD2 agonist 2 (compound 23) enhances antigen presentation in murine bone marrow-derived dendritic cells (BMDCs), highlighting its potential as a vaccine adjuvant.</p>Fórmula:C46H65N3O10Cor e Forma:SolidPeso molecular:820.02Mifamurtide TFA
<p>Mifamurtide TFA: muramyl dipeptide analog, boosts immunity, activates macrophages/monocytes, potential osteosarcoma research.</p>Fórmula:C61H110F3N6O21PCor e Forma:SolidPeso molecular:1351.52TSR-033
CAS:<p>TSR-033 is a human IgG4 antibody with high affinity for LAG-3 (lymphocyte activation gene-3), a co-receptor linked to diminished T cell activity, frequently co-</p>Cor e Forma:LiquidFlunixin
CAS:<p>Flunixin is a nonsteroidal anti-inflammatory drug (NSAID), antipyretic, and analgesic used in pigs, horses, and cattle.</p>Fórmula:C14H11F3N2O2Cor e Forma:SolidPeso molecular:296.24Antifungal agent 123
<p>Antifungalagent 123 (Compound 4b) demonstrates strong affinity for the oxidoreductase of Staphylococcus aureus or membrane proteins of Candida albicans, exhibiting both antibacterial and antifungal properties. Additionally, it is capable of scavenging free radicals, showcasing antioxidant effects. Antifungalagent 123 also inhibits the TLR signaling pathway and possesses anti-inflammatory activity.</p>Fórmula:C21H20N4O3Cor e Forma:SolidPeso molecular:376.409Vemircopan
CAS:<p>Vemircopan is a complement factor D inhibitor.</p>Fórmula:C29H28BrN7O3Cor e Forma:SolidPeso molecular:602.493Inflexuside B
CAS:<p>Inflexuside B, an abietane diterpenoid derived from the aerial parts of Isodon inflexus, effectively inhibits lipopolysaccharide (LPS)-activated NO Synthase in</p>Fórmula:C35H48O11Cor e Forma:SolidPeso molecular:644.75Guaiacol-d3
CAS:<p>Guaiacol-d3 is a deuterated form of Guaiacol, which is a phenolic compound known for its ability to inhibit COX-2 expression and NF-κB activation in response to LPS stimulation, exhibiting anti-inflammatory properties.</p>Fórmula:C7H8O2Cor e Forma:SolidPeso molecular:127.16PSMA-ALB-56
CAS:<p>PSMA-ALB-56: radioactive, PSMA-targeted ligand, antitumor, combines glutamic urea, DOTA, albumin, with iodophenyl or tolyl fragments.</p>Fórmula:C66H95N11O18Cor e Forma:SolidPeso molecular:1330.52RS 09 TFA
<p>RS 09 TFA is a TLR4 agonist and LPS peptide analogue, promotes NF-κB nuclear translocation, induces inflammatory cytokine secretion in RAW264.7 macrophages.</p>Fórmula:C33H50F3N9O11Pureza:99.78%Cor e Forma:SolidPeso molecular:805.8CD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Cor e Forma:Solid4-hydroperoxy 2-Nonenal
CAS:<p>4-HNE, a marker of oxidative stress, arises from oxidized ω-6 fats like linoleic acid and shows cytotoxic and genotoxic effects.</p>Fórmula:C9H16O3Cor e Forma:SolidPeso molecular:172.224BMS-986148
<p>BMS-986148 is a CHO-expressed humanized antibody-drug coupling targeting mesothelin-expressing cells for cytotoxic load delivery.</p>Pureza:98.1% (SDS-PAGE); 99% (SEC-HPLC) - 98.1% (SDS-PAGE); 99% (SEC-HPLC)Cor e Forma:Odour LiquidBermoprofen
CAS:<p>Bermoprofen (AD-1590) is an anti-inflammatory compound with anti-inflammatory and analgesic activity used in the study of gastric ulcers.</p>Fórmula:C18H16O4Pureza:98.72% - 99.28%Cor e Forma:SolidPeso molecular:296.32IL-6-IN-1
<p>IL-6-IN-1 (Compound 22) inhibits the release of IL-6 with an IC50 of 1.065 μM and demonstrates anti-inflammatory activity in LPS-induced acute lung injury in mice.</p>Fórmula:C16H12N2OSCor e Forma:SolidPeso molecular:280.34PSMA-D5
CAS:<p>PSMA-D5 exhibits a binding affinity for PSMA with a Ki of 0.21 nM and becomes useful for PSMA tracing following radiolabeling. When marked with [68Ga], PSMA-D5 contains a DOTA chelator, facilitating the convenient labeling with therapeutic radionuclides such as 177Lu and 225Ac. Additionally, [68Ga]-labeled PSMA-D5 demonstrates exceptional pharmacokinetic properties and significant tumor uptake in 22Rv1 tumors. This compound can be employed in the synthesis and research of radiolabeled conjugates (RDC).</p>Fórmula:C57H80N12O24Cor e Forma:SolidPeso molecular:1317.312'2'-cGAMP (sodium salt)
CAS:<p>2'2'-cGAMP, a synthetic CDN, binds STING in the immune response, inducing IFN-β; binds weaker than 2'3'-cGAMP but stronger than other CDNs.</p>Fórmula:C20H24N10O13P2Cor e Forma:SolidPeso molecular:674.417Dazostinag
CAS:<p>Dazostinag (TAK-676) is a STING agonist with anti-cancer properties, used in making ADCs.</p>Fórmula:C21H22F2N8O10P2S2Cor e Forma:SolidPeso molecular:710.524-Methylamino antipyrine hydrochloride
CAS:<p>4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole.</p>Fórmula:C12H16ClN3OPureza:98%Cor e Forma:SolidPeso molecular:253.73JPE-1375
CAS:<p>JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.</p>Fórmula:C49H63FN10O9Cor e Forma:SolidPeso molecular:955.08HS-243
CAS:<p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>Fórmula:C17H16N4O3Pureza:98.62%Cor e Forma:SolidPeso molecular:324.33Axinelline A
CAS:<p>Axinelline A: COX inhibitor, IC50 of 2.22 μM (COX-2) & 8.89 μM (COX-1), anti-inflammatory.</p>Fórmula:C12H15NO6Cor e Forma:SolidPeso molecular:269.25NG-Hydroxy-L-arginine acetate
CAS:<p>NG-Hydroxy-L-arginine acetate (NOHA acetate) acts as a crucial physiological inhibitor of arginase, playing a vital role in the conversion of arginine to nitric oxide and citrulline via nitric oxide synthase.</p>Fórmula:C6H14N4O3xC2H4O2Cor e Forma:SolidPeso molecular:190.20（free base）STING-IN-13
<p>STING-IN-13 is a selective STING inhibitor that effectively suppresses downstream signaling of the STING pathway and STING-mediated inflammation. It exhibits low toxicity and is suitable for research related to STING-associated inflammatory and autoimmune diseases.</p>Cor e Forma:Odour SolidBiotin-labeled Agatolimod sodium
<p>Biotin-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of cellular uptake and localization of</p>Cor e Forma:Odour SolidBiotin-labeled ODN 2216 sodium
<p>Biotin-labeled ODN 2216 (sodium) serves as a specific agonist for human TLR9 (toll-like receptor 9), facilitating the assessment of CpG ODN cellular uptake and</p>Cor e Forma:Odour SolidAntitumor agent-188
<p>Antitumor agent-188 (compound C6) exhibits α-glucosidase inhibitory activity and anticancer properties. It induces excessive ROS production, thereby triggering oxidative stress.</p>Fórmula:C25H44FN3O7Cor e Forma:SolidPeso molecular:517.63CU-115
CAS:<p>CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7, respectively.</p>Fórmula:C21H11F7INO2Pureza:99.96%Cor e Forma:SolidPeso molecular:569.21diABZI STING agonist-1 trihydrochloride
CAS:<p>diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist.</p>Fórmula:C42H54Cl3N13O7Pureza:95.33% - 99.55%Cor e Forma:SolidPeso molecular:959.32Multinoside A
CAS:<p>Multinoside A is a useful organic compound for research related to life sciences. The catalog number is T124593 and the CAS number is 59262-54-3.</p>Fórmula:C27H30O16Cor e Forma:SolidPeso molecular:610.521(Rac)-γ-Tocopherol
CAS:<p>(Rac)-γ-Tocopherol (DMPBQ) is an isoform of Vitamin E that undergoes conversion to γ-Tocopherol through the action of tocopherol cyclase.</p>Fórmula:C28H48O2Cor e Forma:SolidPeso molecular:416.68Carboxy-PTIO
CAS:<p>Carboxy-PTIO rapidly scavenges NO, forming NO2, key in preventing hypotension and shock in rats.</p>Fórmula:C14H17N2O4Cor e Forma:SolidPeso molecular:277.3STING agonist-25
CAS:<p>STING agonist-25 is a non-nucleotide that activates STING, enhances immune response, and is active against SARS-CoV strains.</p>Fórmula:C36H41N13O6Cor e Forma:SolidPeso molecular:751.79NLRP3-IN-15
CAS:<p>NLRP3-IN-15: potent, selective NLRP3 inflammasome inhibitor; IC50 0.114 μM for IL-1β; for inflammation research.</p>Fórmula:C22H19NO4Cor e Forma:SolidPeso molecular:361.39QKY-613
CAS:<p>QKY-613 is a prodrug designed to enhance immune surveillance by targeting nucleic acid modification pathways. It selectively facilitates the incorporation of 6mdA (N6-methyl-deoxyadenosine) into viral DNA, boosting the DNA's phase separation potential and subsequently increasing cGAS activation levels to strengthen host immune surveillance. In mouse models of viral infection, QKY-613 significantly reduced mortality in aged mice. This compound holds promise for studying immune surveillance mechanisms based on nucleic acid modifications.</p>Fórmula:C27H31N6O7PCor e Forma:SolidPeso molecular:582.55Decylubiquinone
CAS:<p>Decylubiquinone (DUb) is a coenzyme Q10 analog with anticancer activity, inhibiting the growth and metastasis of breast cancer.</p>Fórmula:C19H30O4Pureza:99.32% - 99.92%Cor e Forma:SolidPeso molecular:322.44Anti-inflammatory agent 93
<p>Compound 2g (Anti-inflammatory agent 93) is an active compound that exhibits analgesic activity.</p>Fórmula:C27H17Cl2N3O2Cor e Forma:SolidPeso molecular:486.35CRX-526
CAS:<p>CRX-526, a TLR4 antagonist, protects against advanced diabetic nephropathy.</p>Fórmula:C69H127N2O19PPureza:98%Cor e Forma:SolidPeso molecular:1319.72IMGN-779
<p>IMGN-779 (Anti-CD33 Antibody) is a humanized antibody targeting CD33 with antileukemic activity, which can be used to study leukemia.</p>Pureza:>95%Cor e Forma:Odour Liquid2-Iminobiotin
CAS:<p>2-Iminobiotin inhibits iNOS/nNOS; Ki: 21.8 μM (mouse iNOS), 37.5 μM (rat nNOS).</p>Fórmula:C10H17N3O2SPureza:98%Cor e Forma:SolidPeso molecular:243.33Anti-Human MSLN Antibody (Clone HN1)
<p>Anti-Human MSLN Antibody (Clone HN1) is a humanised monoclonal antibody targeting MSLN (Mesothelin), , blocks the interaction between MSLN and CA125, cancer .</p>Pureza:95%Cor e Forma:Odour LiquidCbl-b-IN-28
<p>Cbl-b-IN-28 (Compound B2) is an orally active Cbl-b inhibitor. It enhances the function of immune cells by promoting the secretion of cytokines like IL-2 and modulating the phosphorylation levels of key proteins in the T cell receptor signaling pathway. Cbl-b-IN-28 is applicable in cancer immunology research.</p>Cor e Forma:Odour SolidLY-402913
CAS:<p>LY-402913 is a selective multidrug resistance protein (MRP1) inhibitor.</p>Fórmula:C28H24ClN3O6Pureza:99.73%Cor e Forma:SolidPeso molecular:533.96PSB-12379 ditriethylamine salt
<p>PSB-12379 ditriethylamine salt, a nucleotide analogue, is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).</p>Fórmula:C30H53N7O9P2Pureza:98.26% - 99.44%Cor e Forma:SolidPeso molecular:717.73iNOs-IN-6
<p>iNOs-IN-6 is an anti-inflammatory agent known for inhibiting the expression of NF-κB, iNOS, and MAPK with an IC50 ranging from 0.2 to 0.62 μM. Additionally, it decreases the levels of pro-inflammatory mediators, such as IL-6, TNF-α, and IL-1β, with an IC50 ranging from 0.4 to 0.69 μM.</p>Cor e Forma:Odour SolidDithianon
CAS:<p>Dithianon: broad-spectrum anthraquinone fungicide; sticks to leaves/fruits; controls various fungi in some produce.</p>Fórmula:C14H4N2O2S2Pureza:98%Cor e Forma:SolidPeso molecular:296.32Vadastuximab
<p>Vadastuximab (Anti-Human CD33 Recombinant Antibody) is a humanized anti-CD33 monoclonal antibody for the study of acute myeloid leukemia (AML).</p>Pureza:98.5% (SDS-PAGE); 97.3% (SEC-HPLC) - 98.5% (SDS-PAGE); 97.3% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.5 kDaCRX 527
CAS:<p>CRX 527 is a TLR4 ligand and serves as an adjuvant for peptide cancer vaccines, enhancing anti-tumor immune responses. CRX 527 also induces hematopoietic stem cell (HSC) differentiation, increasing the proportion and number of LSK cells, and promotes their differentiation into macrophages. This activation bolsters immune defense and protects intestinal epithelium from radiation damage.</p>Fórmula:C81H151N2O19PCor e Forma:SolidPeso molecular:1488.04Siegesbeckialide I
<p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>Fórmula:C20H28O6Cor e Forma:SolidPeso molecular:364.43SN50
CAS:<p>SN50 is a cell-permeable inhibitor of NF-κB nuclear translocation that protects against ventilator-induced acute lung injury in rats.</p>Fórmula:C129H230N36O29SPureza:99.91%Cor e Forma:SolidPeso molecular:2781.5Damnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Fórmula:C16H12O5Cor e Forma:SolidPeso molecular:284.267Prezalumab
CAS:<p>Prezalumab (AMG 557) is a human IgG2 monoclonal antibody against ICOSL and BAFF.</p>Pureza:> 95%Cor e Forma:LiquidPeso molecular:145.42 kDaPSMα3
CAS:<p>PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies.</p>Fórmula:C128H192N28O30SCor e Forma:SolidPeso molecular:2635.174'-hydroxy Flurbiprofen
CAS:<p>4'-hydroxy Flurbiprofen can be used in related research in the field of life sciences. Its product number is T35722 and CAS number is 52807-12-2.</p>Fórmula:C15H13FO3Cor e Forma:SolidPeso molecular:260.264TPNA10168
CAS:<p>Compound Fr13590, with CAS No. 957942-34-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13590 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C9H9ClO2S2Cor e Forma:SolidPeso molecular:248.75SN50 TFA
<p>SN50 TFA is an inhibitor of NF-κB and attenuates alveolar hypercoagulation and fibrinolysis inhibition. SN50 TFA can be used in studies about ARDS.</p>Fórmula:C129H230N36O29S·XCF3COOHCor e Forma:SolidPeso molecular:2781.5 (free base)Somantadine
CAS:<p>Somantadine has antiviral activities and can be used for research on preventing and treating coronavirus-related diseases.</p>Fórmula:C14H25NPureza:99.9%Cor e Forma:SolidPeso molecular:207.35β-Interleukin II (44-56)
<p>β-Interleukin II is a peptide with the sequence NH2-ILE-LEU-ASN-GLY-ILE-ASN-ASN-TYR-LYS-ASN-PRO-LYS-LEU-COOH.</p>Fórmula:C68H113N19O19Pureza:98%Cor e Forma:SolidPeso molecular:1500.74QX-005N
QX 005N is a humanized monoclonal anti-CD124/IL4R/IL-4Rα antibody. It is applicable in research related to asthma.Cor e Forma:Odour LiquidAntiviral agent 61
<p>Antiviralagent 61 (compound Z40) serves as an effective antiviral agent with activity against Tomato Spotted Wilt Virus (TSWV), exhibiting an EC50 value of 252 µg/mL. It increases the RNA expression of Ndufb9, COX6B, 7.1.2.2, E, COX5B, Ndufs4, and SDHB, while reducing the expression of Ndufb7, Ndufa5, and G.</p>Fórmula:C22H23N5O4SCor e Forma:SolidPeso molecular:453.51Pepinh-MYD
CAS:<p>Pepinh-MYD, a MyD88 inhibitor, incorporates both a domain sequence from MyD88 TIR and a protein transduction sequence to facilitate cell membrane penetration. This compound disrupts MyD88-mediated TLR signaling pathways, effectively inhibiting associated immune responses. Its design is particularly useful for investigating MyD88's function in viral infections.</p>Fórmula:C151H248N50O35S2Cor e Forma:SolidPeso molecular:3388.03Pelgifatamab
CAS:<p>Pelgifatamab (BAY-2315497) is a prostate-specific membrane antigen (PSMA) antibody with potential anticancer activity that can be used to study prostate cancer.</p>Pureza:97.9% (SDS-PAGE); 95.1% (SEC-HPLC) - 97.9% (SDS-PAGE); 95.1% (SEC-HPLC)Cor e Forma:LiquidEnglumafusp alfa
<p>Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion protein combining a CD19-specific antibody domain with trimerized extracellular domains of human 4-1BBL,</p>Cor e Forma:Odour LiquidMS7829
<p>MS7829 is a first-class DUBTAC targeting cGAS, a critical component in the cGAS-STING pathway.</p>Cor e Forma:Odour SolidABX-IL8
<p>ABX-IL8 is a humanized antibody targeting IL-8, capable of interfering with tube formation in human umbilical vein endothelial cells.</p>Pureza:>95%Cor e Forma:LiquidPeso molecular:145.5 kDaTD139
CAS:<p>TD139 is an inhaled small molecule inhibitor of galectin-3 (Gal-3) with potential anti-fibrotic activity. Cost-effective and quality-assured.</p>Fórmula:C28H30F2N6O8SPureza:97.82% - 99.66%Cor e Forma:SolidPeso molecular:648.64AHR antagonist 5 free base
CAS:<p>AHR antagonist 5 free base is an orally active AHR antagonist and exhibits anticancer activity.Cost-effective and quality-assured.</p>Fórmula:C25H24FN7Pureza:99.88%Cor e Forma:SolidPeso molecular:441.5FITC-labeled ODN 2395 sodium
<p>FITC-labeled ODN 2395 (sodium), a class C oligodeoxynucleotide and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and localization through</p>Cor e Forma:Odour SolidIACS-8803 diammonium
<p>IACS-8803 diammonium, a potent cyclic dinucleotide STING agonist, demonstrates robust systemic antitumor efficacy [1].</p>Fórmula:C20H29FN12O9P2S2Cor e Forma:SolidPeso molecular:726.6CIB-1476
<p>CIB-1476, a caspase-1 inhibitor, effectively reduces joint swelling in mouse models of arthritis and demonstrates lasting anti-inflammatory effects. This compound achieves its benefits by blocking IL-1β production, NF-κB activation, and GSDMD-mediated pyroptosis, all of which are triggered by the NLRP3 inflammasome.</p>Fórmula:C28H28N2O6SCor e Forma:SolidPeso molecular:520.6Septeremophilane E
<p>Septeremophilane E, from Septoria rudbeckiae fungus, inhibits NO production.</p>Fórmula:C21H26O5Cor e Forma:SolidPeso molecular:358.43OVA Peptide(257-264)
CAS:<p>OVA Peptide(257-264) is an ovalbumin octamer Peptide expressed by class I MHC molecule h-2kb.</p>Fórmula:C45H74N10O13Pureza:99.53%Cor e Forma:SolidPeso molecular:963.13Pirenoxine
CAS:<p>Pirenoxine is an agent with anti-cataractogenesis activity by interacting with calcium ions or selenite which could lead to the formation of lens cataract.</p>Fórmula:C16H8N2O5Cor e Forma:SolidPeso molecular:308.25Dovanvetmab
CAS:<p>Dovanvetmab (ZTS-00521505) is an IgG1-κ monoclonal antibody that targets feline interleukin 31 (Felcat IL31), primarily produced in Chinese Hamster Ovary (CHO)</p>Cor e Forma:LiquidDecamethylene glycol
CAS:<p>Decamethylene glycol, a reagent for studying modified oligonucleotides with anticancer effects, is also researched in myrrh and frankincense oil composition.</p>Fórmula:C10H22O2Pureza:98%Cor e Forma:White Crystals Or PowderPeso molecular:174.28R-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Fórmula:C22H19N3O2S2Cor e Forma:SolidPeso molecular:421.54diABZI-V/C-DBCO
<p>Compound 3 (diABZI-V/C-DBCO) functions as an efficient STING agonist. This compound acts by releasing diABZI-amine under the action of cathepsin B to activate STING, thereby inducing the production of interferon and other immune-activating molecules, which enhances the immune system's response to tumors. In THP1-Dual cells, the EC50 values for STING activation by diABZI-V/C-DBCO and diABZI-amine are 1.47 nM and 0.144 nM, respectively, and in primary mouse splenic cells, the EC50 values are 7.7 µM and 0.17 µM, respectively. diABZI-V/C-DBCO is useful for research in the field of cancer immunotherapy.</p>Fórmula:C78H89N19O13Cor e Forma:SolidPeso molecular:1500.66Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34-PEG2/PEG1)-amide-C3-COOH is a TLR4 inhibiting linker, reducing inflammation in endotoxemia and enterocolitis mouse models.</p>Fórmula:C78H125N7O42Cor e Forma:SolidPeso molecular:1832.85Paneolilludinic acid
CAS:<p>Paneolilludinic acid from Cryptomarasmius aucubae fungus inhibits NO production.</p>Fórmula:C15H22O3Cor e Forma:SolidPeso molecular:250.33M-5011
CAS:<p>M-5011: NSAID and immunomodulator for pain and inflammation; ED50 0.63mg/kg; reduces bone loss in arthritis; low ulcer risk.</p>Fórmula:C14H14O2SPureza:98%Cor e Forma:SolidPeso molecular:246.32Pegaldesleukin
CAS:<p>Pegaldesleukin, a PEG-IL2 conjugate, exhibits antiviral properties, potentially slowing HIV progression, preserving immune function.</p>Cor e Forma:LiquidAra-F-NAD+ sodium
<p>Ara-F-NAD+ sodium, an arabino analogue of NAD+, serves as a potent, reversible, and slow-binding inhibitor of the CD38 NADase [1] [2].</p>Fórmula:C21H25FN7NaO13P2Cor e Forma:SolidPeso molecular:687.4NLRP3-IN-45
<p>NLRP3-IN-45 (D6) serves as an inhibitor specifically targeting the NLRP3 inflammasome, demonstrated through its ability to curb the activity of IL-1β (IC 50 = 41.79 nM). It effectively prevents the activation of the NLRP3 inflammasome while sparing the initial stages of its activation process. Furthermore, NLRP3-IN-45 has been shown to selectively inhibit NLRP3 inflammasome activation in the LPS-induced acute lung injury (ALI) mouse model.</p>Fórmula:C27H30FNO6Cor e Forma:SolidPeso molecular:483.53Eramkafusp Alfa
<p>Eramkafusp alfa is a human IgG1 antibody that targets the murine B lymphocyte antigen CD20, also known as MS4A1 [1].</p>Cor e Forma:Odour LiquidAβ-IN-6
<p>Aβ-IN-6 is an orally active compound exhibiting anti-inflammatory, antioxidant, and anti-oligomeric activities, with significant implications for Alzheimer's</p>Fórmula:C28H31N3O4Cor e Forma:SolidPeso molecular:473.56CHBO4
CAS:<p>CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and</p>Fórmula:C15H10BrFOPureza:98.14%Cor e Forma:SolidPeso molecular:305.14HNGF6A
CAS:<p>increases glucose stimulated insulin secretion and glucose metabolism</p>Fórmula:C112H198N34O31S2Pureza:98%Cor e Forma:SolidPeso molecular:2581.11Withangulatin A
CAS:<p>Withangulatin A, a COX-2 inhibitor from Physalis angulata, has anti-tumor and anti-inflammatory effects.</p>Fórmula:C30H38O8Cor e Forma:SolidPeso molecular:526.62Mesalamine impurity P
CAS:<p>Mesalamine impurity P, a 5-Aminosalicylic acid derivative, is a PPARγ agonist, inhibiting PAK1 and NF-κB.</p>Fórmula:C13H11NO6SCor e Forma:SolidPeso molecular:309.30Siplizumab
CAS:<p>Siplizumab (MEDI-507), an IgG1 antibody targeting CD2, depletes T cells, may treat psoriasis.</p>Pureza:100% (SEC-HPLC) - > 95%Cor e Forma:LiquidPeso molecular:147.24 kDaNrf2 activator 18
<p>Nrf2 activator 18 (Compound 11a) is an orally active activator of the Keap1/Nrf2/HO-1 signaling pathway, promoting Nrf2 nuclear translocation and enhancing antioxidant effects. It inhibits IL-6 release with an IC50 of 4.816 μM. In a mouse model of PM2.5-induced lung injury, Nrf2 activator 18 demonstrates anti-inflammatory activity.</p>Fórmula:C23H24FN3OCor e Forma:SolidPeso molecular:377.45
