
Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(62 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3055 produtos de "Imunologia e Inflamação"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Lunsekimig
<p>Lunsekimig (SAR443765) is an IL-13/TSLP bis-antibody that links a nano-antibody targeting IL-13 and a variable region of the heavy chain (VHH) targeting TSLP for use in asthma research.</p>Cor e Forma:Odour LiquidTucotuzumab
CAS:<p>Tucotuzumab: IgG1 monoclonal antibody targeting EpCAM, fused with IL-2, used as an immunosuppressant and antineoplastic.</p>Pureza:95%Cor e Forma:LiquidCC-90002
CAS:<p>CC-90002: humanized anti-CD47 mAb, high affinity, subnanomolar Kd. For hematologic and solid tumor research.</p>Cor e Forma:LiquidInolimomab
CAS:<p>Inolimomab is a monoclonal antibody targeting CD25 (IL-2R α chain) for studying acute graft-versus-host disease (aGVHD).</p>Pureza:95% - 95%Cor e Forma:LiquidSerotonin Creatinine Sulfate Monohydrate
CAS:Fórmula:C14H19N5O2·H2SO4·H2OPureza:>98.0%(T)Cor e Forma:White to Light yellow powder to crystalPeso molecular:405.43Indometacin Farnesil
CAS:Fórmula:C34H40ClNO4Pureza:>98.0%(HPLC)Cor e Forma:Light yellow to Yellow to Orange clear liquidPeso molecular:562.15Azathioprine
CAS:Fórmula:C9H7N7O2SPureza:>98.0%(T)(HPLC)Cor e Forma:Light yellow to Yellow to Green powder to crystalPeso molecular:277.26QNZ
CAS:Fórmula:C22H20N4OPureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Green powder to crystalPeso molecular:356.43Ketorolac-d5
CAS:<p>Ketorolac-d5 is a deuterated compound of ketorolac for isotope tracing. Ketorolac is a non-steroidal anti-inflammatory agent and inhibitor of COX-1 and COX-2.</p>Fórmula:C15H8D5NO3Pureza:98.99%Cor e Forma:SolidPeso molecular:260.3Maresin 1
CAS:Maresin 1 is biosynthesized by macrophages (MΦ) and possesses significant anti-inflammatory activity that attenuates LPS-induced lung injury in mice.Fórmula:C22H32O4Cor e Forma:SolidPeso molecular:360.49Lusvertikimab
CAS:<p>Lusvertikimab (OSE-127) is a humanized anti-IL7R antibody with anti-leukemic efficacy and can be used to study leukemia.</p>Pureza:95% - 98.4% (SDS-PAGE); 99% (SEC-HPLC)Cor e Forma:LiquidNepafenac-d5
CAS:<p>Nepafenac D5 is the deuterium labeled Nepafenac, which is a selective inhibitor of COX-2 .</p>Fórmula:C15H14N2O2Pureza:98%Cor e Forma:SolidPeso molecular:259.31D228
CAS:<p>D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).</p>Fórmula:C22H28O12Pureza:99.91%Cor e Forma:SolidPeso molecular:484.45BMS-378806
CAS:BMS-378806 (BMS-806) selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.Fórmula:C22H22N4O4Pureza:99.93%Cor e Forma:SolidPeso molecular:406.43FAPI-2
CAS:<p>FAPI-2 is a specific inhibitor of fibroblast-activated protein based on the radiotracer FAP labeling, and has anticancer activity.</p>Fórmula:C40H56N10O10Pureza:98.76%Cor e Forma:SolidPeso molecular:836.933,4-DAA
CAS:3,4-DAA has anti-inflammatory activity and inhibits EOC20 cell-induced nitric oxide synthase (iNOS) induced by IFN-γ and lipopolysaccharide.Fórmula:C18H17NO6Pureza:98%Cor e Forma:SolidPeso molecular:343.33Amfenac
CAS:<p>Amfenac promotes apoptosis in ARPE-19 cell culture.</p>Fórmula:C15H13NO3Cor e Forma:SolidPeso molecular:255.27AHR-10037
CAS:<p>AHR-10037, a NSAID, offers pain relief, fever reduction, safety, and low stomach risk, acting as a prodrug for COX inhibitors.</p>Fórmula:C15H13ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:288.73Vopikitug
CAS:<p>Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.</p>Pureza:99.1% (SDS-PAGE); 96.5% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)Cor e Forma:LiquidAzacyclonol hydrochloride
CAS:<p>Azacyclonol hydrochloride can be used in the treatment of chronic schizophrenia.</p>Fórmula:C18H22ClNOCor e Forma:Off White Crystalline PowderPeso molecular:303.83Kamebakaurin
CAS:<p>Kamebakaurin combats liver toxicity, cancer, inflammation, and neuroinflammation by blocking NF-κB, HIF-1α, and key signaling pathways.</p>Fórmula:C20H30O5Pureza:98.05%Cor e Forma:SolidPeso molecular:350.45TMV-IN-9
CAS:<p>TMV-IN-9 (compound A6) is an antiviral agent that exhibits exceptional inactivation effects against Tobacco Mosaic Virus (TMV), with an EC50 of 62.8 μg/mL. It demonstrates strong binding capabilities to the TMV capsid protein, with a binding affinity of 1.862 μM. Moreover, TMV-IN-9 significantly disrupts the integrity of TMV particles, thereby preventing the virus from infecting the host.</p>Fórmula:C20H20O8Cor e Forma:SolidPeso molecular:388.37AZD4144
CAS:<p>AZD4144 is a potent and selective NLRP3 inhibitor (IC50 = 54 nM) that reducs IL-1β and IL-18 production for immune disorders.</p>Fórmula:C18H16F3N3O3Pureza:99.02%Cor e Forma:SoildPeso molecular:379.33(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one
CAS:(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one is a major mechanism of Sinomenine.Fórmula:C18H21NO4Pureza:97.85%Cor e Forma:SoildPeso molecular:315.36Etokimab
CAS:<p>Etokimab (ANB-020) is a humanised monoclonal antibody targeting IL-33, neutrophil migration, atopic dermatitis, asthma, and sinusitis.</p>Pureza:95%Cor e Forma:LiquidAvasopasem manganese
CAS:<p>Avasopasem manganese is a drug candidate of superoxide dismutase mimetic.</p>Fórmula:C21H35Cl2MnN5Pureza:98%Cor e Forma:SolidPeso molecular:483.38Pelubiprofen
CAS:<p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>Fórmula:C16H18O3Pureza:99.69%Cor e Forma:SolidPeso molecular:258.31Catalase
CAS:<p>Catalase, an enzyme, metabolizes H2O2 and ROS; its expression and localization change significantly in tumors.</p>Pureza:≥98%Cor e Forma:Small Colorless Crystals Or Powder At Room Temperature Almost Odourless Small Colourless Crystals Or A White Crystalline PowderAllopurinol Sodium
CAS:<p>Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.</p>Fórmula:C5H4N4NaOPureza:99.93%Cor e Forma:SolidPeso molecular:159.1E3330
CAS:<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Fórmula:C21H30O6Pureza:99.52%Cor e Forma:SolidPeso molecular:378.46CB2 modulator 1
CAS:<p>CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.</p>Fórmula:C18H19F3N4O2Pureza:99.6%Cor e Forma:SolidPeso molecular:380.36HPN-01
CAS:HPN-01 (IKK inhibitor XII) is an IKK inhibitor that inhibits IKK-α and IKK-ε, prolongs the lifespan of mice, and can be used to study immune disorders.Fórmula:C19H16ClN3O3SPureza:98.07% - 98.17%Cor e Forma:SolidPeso molecular:401.87Eltrombopag methyl ester
CAS:<p>Eltrombopag methyl ester, a Tpo receptor agonist derivative, boosts platelet production for thrombocytopenia research.</p>Fórmula:C26H24N4O4Cor e Forma:SolidPeso molecular:456.49RIP2 Kinase Inhibitor 3
CAS:<p>RIP2 Kinase Inhibitor 3 is a potent and selective inhibitor of RIP2 with an IC50 of 1 nM.</p>Fórmula:C19H24N4O3SPureza:99.32% - 99.52%Cor e Forma:SolidPeso molecular:388.48hDDAH-1-IN-1
CAS:hDDAH-1-IN-1 is a selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) (Ki: 18 μM).Fórmula:C8H20N4OPureza:98%Cor e Forma:SolidPeso molecular:188.27MIP-1072
CAS:<p>MIP-1072 is the prostate-specific membrane antigen inhibitor.</p>Fórmula:C19H26IN3O7Pureza:98%Cor e Forma:SolidPeso molecular:535.33GSK223
CAS:GSK223 is an iE-DAP-stimulated IL-8 release inhibitor via the NOD1 signaling pathway.Fórmula:C21H18FN3O3S2Pureza:98%Cor e Forma:SolidPeso molecular:443.51NCX1022
CAS:<p>NCX1022 is a NO-releasing derivative of Hydrocortisone. It is the most widely used anti-inflammatory drug for the treatment of skin inflammation.</p>Fórmula:C29H35NO9Pureza:98%Cor e Forma:SolidPeso molecular:541.59LC-R 505
CAS:<p>LC-R 505 is an anti-inflammatory.</p>Fórmula:C20H26N2O5SCor e Forma:SolidPeso molecular:406.5FR20
CAS:<p>FR20 is a human microsomal prostaglandin synthase 1 (mPGES 1) inhibitor.</p>Fórmula:C31H25Cl2N3O2Cor e Forma:SolidPeso molecular:542.46Anisodine hydrobromide
CAS:<p>Anisodine hydrobromide is an inhibitor of adenosine kinase.</p>Fórmula:C17H22BrNO5Cor e Forma:White Crystals Or Crystalline PowderPeso molecular:400.27Oxyfenamate
CAS:Oxyfenamate has anti-anxiety actions. It is also used in anxiety neuroses.Fórmula:C11H15NO3Pureza:98%Cor e Forma:SolidPeso molecular:209.24S-MTC
CAS:<p>S-MTC is a selective inhibitor of type I nitric oxide synthase.</p>Fórmula:C7H15N3O2SPureza:98%Cor e Forma:Off-White Powder / White SolidPeso molecular:205.28RI-962
CAS:<p>RI-962 is a potent and selective inhibitor of RIPK1 that protects cells from necrotic apoptosis by inhibiting RIPK1, RIPK3, and MLKL phosphorylation.</p>Fórmula:C28H28N6O2Pureza:99.39%Cor e Forma:SoildPeso molecular:480.56L 748780
CAS:<p>L 748780 is a selective inducible COX-2 inhibitor.</p>Fórmula:C19H14Cl3NO4Pureza:98%Cor e Forma:SolidPeso molecular:426.68Tiazotic acid
CAS:<p>Tiazotic acid is an agent with the activity of antioxidant.</p>Fórmula:C5H7N3O2SPureza:98%Cor e Forma:SolidPeso molecular:173.19ZXX2-77
CAS:<p>ZXX2-77 is a cyclooxygenase-1 inhibitor.</p>Fórmula:C13H13ClN2O2SPureza:98%Cor e Forma:SolidPeso molecular:296.77IRAK inhibitor 4
CAS:<p>IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 inhibitor.</p>Fórmula:C33H35F3N6O3Pureza:98%Cor e Forma:SolidPeso molecular:620.66L-NIL hydrochloride
CAS:<p>selective inhibitor of inducible nitric oxide synthase</p>Fórmula:C8H18ClN3O2Pureza:98%Cor e Forma:White To Off-White SolidPeso molecular:223.7NCX-6560
CAS:NCX-6560 is a novel NO-releasing derivative of atorvastatin, with those of atorvastatin.Fórmula:C37H42FN3O8Cor e Forma:SolidPeso molecular:675.74Fagaramide
CAS:<p>Fagaramide possesses Antiplasmodial activity.</p>Fórmula:C14H17NO3Pureza:98%Cor e Forma:SolidPeso molecular:247.29S-Isopropylisothiourea hydrobromide
CAS:<p>S-Isopropylisothiourea hydrobromide is an iNOS inhibitor.</p>Fórmula:C4H11BrN2SPureza:98%Cor e Forma:SolidPeso molecular:199.11LY 150310
CAS:<p>LY 150310, a histamine H1-receptor antagonist, can alter prostanoid concentrations in vitro and in vivo.</p>Fórmula:C13H14N2Cor e Forma:SolidPeso molecular:198.26IRAK4-IN-16
CAS:<p>IRAK4-IN-16 inhibits IRAK4 at 2.5nM; cytotoxic to OCI-LY10, TMD8, Ramos, HT cells with IC50s of 0.2, 0.2, 0.6, 2.7μM.</p>Fórmula:C17H20F2N8OCor e Forma:SolidPeso molecular:390.39Nω-Propyl-L-arginine hydrochloride
CAS:<p>Highly selective and potent inhibitor of nNOS (Ki = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo.</p>Fórmula:C9H21ClN4O2Cor e Forma:SolidPeso molecular:252.74L 669083
CAS:<p>L 669083 is two classes of potent leukotriene biosynthesis inhibitors photoaffinity analogue.</p>Fórmula:C29H29IN4O5SPureza:98%Cor e Forma:SolidPeso molecular:672.54TYT-1
CAS:<p>TYT-1 is a West Nile virus (WNV) inhibitor, antiviral (IC₅₀ = 0.7 mM) by blocking the pre-assembly replication step following viral entry into cells.</p>Fórmula:C21H17N3O2S3Pureza:98.49%Cor e Forma:SolidPeso molecular:439.57SNAP 398299
CAS:<p>SNAP 398299 is a Glycopeptide Receptor Type 3 (Gal3) antagonist with anxiolytic and antidepressant-like effects and is used in the study of mood disorders.</p>Fórmula:C27H24F3N3O2Pureza:97.16%Cor e Forma:SolidPeso molecular:479.49APY0201
CAS:<p>APY0201: potent, specific ATP-competitive PIKfyve inhibitor; IC50=5.2 nM; blocks PtdIns3P to PtdIns(3,5)P2 conversion.</p>Fórmula:C23H23N7OPureza:98% - 99.74%Cor e Forma:SolidPeso molecular:413.48T-5342126
CAS:<p>T-5342126: TLR4 antagonist, lowers LPS-induced NO in cells (IC50=27.8 μM) & cytokines in blood, cuts ethanol intake & Iba1 in mice.</p>Fórmula:C25H32ClN3O3Cor e Forma:SolidPeso molecular:457.99IRAK4-IN-17
CAS:<p>IRAK4-IN-17 is a potent IRAK4 inhibitor with a 1.3 nM IC50, key for DLBCL research.</p>Fórmula:C17H20F2N8OCor e Forma:SolidPeso molecular:390.39HPGDS inhibitor 3
CAS:<p>HPGDS inhibitor 3: oral, potent (IC50=9.4 nM; EC50=42 nM), selective, no CNS toxicity, good pharmacokinetics, anti-inflammatory.</p>Fórmula:C21H27N3O2Cor e Forma:SolidPeso molecular:353.46OPC-163493
CAS:<p>OPC-163493 is an orally active, liver-targeted mitochondrial uncoupling agent that diminishes Δψ (delta psi) and mitochondrial ROS (reactive oxygen species)</p>Fórmula:C14H8F3N5SPureza:98%Cor e Forma:SolidPeso molecular:335.31L-Kynurenine sulfate
CAS:<p>L-Kynurenine sulfate activates AHR, leading naive T cells to anti-inflammatory Treg phenotype.</p>Fórmula:C10H14N2O7SCor e Forma:SolidPeso molecular:306.29STING modulator-4
CAS:STING modulator-4: competitive, Ki=0.0933 μM (R232H STING), EC50 >10 μM (p-IRF3, THP-1 cells).Fórmula:C17H18N8OCor e Forma:SolidPeso molecular:350.38BC12-4
CAS:<p>BC12-4 is a novel potent inhibitor of IL-2 secretion, it has potent immunomodulatory activity.</p>Fórmula:C19H14N2O3Cor e Forma:SolidPeso molecular:318.333-Bromo-7-nitroindazole
CAS:<p>3-Bromo-7-nitroindazole specifically inhibits nNOS, impacting NO synthesis in brain/body.</p>Fórmula:C7H4BrN3O2Pureza:98.2%Cor e Forma:Yellowish SolidPeso molecular:242.03c-di-AMP
CAS:<p>c-di-AMP (Cyclic diadenylate) is a STING agonist. It binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway.</p>Fórmula:C20H24N10O12P2Pureza:98%Cor e Forma:SolidPeso molecular:658.41Keap1-Nrf2-IN-13
CAS:<p>Keap1-Nrf2-IN-13 is a PPI inhibitor (IC50: 0.15 μM) that binds Keap1 strongly, useful for oxidative stress and inflammation research.</p>Fórmula:C28H32N2O10S2Cor e Forma:SolidPeso molecular:620.69AN3485 Hydrochloride
CAS:<p>AN3485 Hydrochloride is an anti-inflammatory agent and a TLRs inhibitor, reducing ear swelling induced by PMA.</p>Fórmula:C14H14BCl2NO3Pureza:98.34%Cor e Forma:SolidPeso molecular:325.98C5aR-IN-2
CAS:<p>C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.</p>Fórmula:C36H40FN5O2Cor e Forma:SolidPeso molecular:593.73Bay 65-1942 free base
CAS:Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.Fórmula:C22H25N3O4Pureza:98%Cor e Forma:SolidPeso molecular:395.45COX-2-IN-28
CAS:<p>COX-2-IN-28 is a potent and selective COX-2 inhibitor capable of acting on COX-2 (IC50: 0.054 μM), 15-LOX (IC50: 2.14 μM) and COX-1 (IC50: 13.21 μM).</p>Fórmula:C30H27N7S3Cor e Forma:SolidPeso molecular:581.78Enflicoxib
CAS:<p>Enflicoxib is an effective treatment for canine osteoarthritis pain and inflammation, with faster onset than mavacoxib, improving veterinary outcomes.</p>Fórmula:C16H12F5N3O2SPureza:99.88%Cor e Forma:SolidPeso molecular:405.34AVE-9488
CAS:<p>AVE-9488 is a novel endothelial NO synthase (eNOS) enhancer that upregulates eNOS expression, induces NO production, and may ameliorate portal hypertension.</p>Fórmula:C16H14FNOPureza:99.87%Cor e Forma:SolidPeso molecular:255.29AP-1/NF-κB activation inhibitor 1
CAS:<p>AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basal</p>Fórmula:C13H11F3N4O4Pureza:99.52% - 99.91%Cor e Forma:SolidPeso molecular:344.25CD73-IN-8
CAS:<p>CD73-IN-8 blocks CD73, hindering adenosine production that supports tumor growth, flagged as compound 57 in WO2022052886A1.</p>Fórmula:C17H13ClN4O2Cor e Forma:SolidPeso molecular:340.76STING Agonist 12b
CAS:<p>STING agonist 12b activates human/mouse STING, binds with Kd 26.4 μM, prompts interferon, and induces TNF-a, IL-6, IP-10, IL-1b in THP-1 cells.</p>Fórmula:C16H15NO2Cor e Forma:SolidPeso molecular:253.3K-80001
CAS:<p>K-80001 is a selective RXRα ligand and a COX-1/2 inhibitor, exhibiting IC50 values of 82.9μM for RXRα, 3.4μM for COX-1, and 1.2μM for COX-2, respectively [1].</p>Fórmula:C20H17FO2Cor e Forma:SolidPeso molecular:308.35Bay 65-1942 hydrochloride
CAS:<p>Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.</p>Fórmula:C22H26ClN3O4Cor e Forma:SolidPeso molecular:431.91KIN1400
CAS:<p>KIN1400 activates IRF3, boosts antiviral immunity, stimulates IFNbeta, and inhibits WNV, DV, and HCV.</p>Fórmula:C24H17F2N3O2SPureza:98%Cor e Forma:SolidPeso molecular:449.47Emlenoflast sodium
CAS:Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome,Fórmula:C19H24N4NaO3SCor e Forma:SolidPeso molecular:411.47Cyclic-di-GMP
CAS:<p>Cyclic-di-GMP is a STING agonist and ubiquitous second messenger, which regulates the formation, motility and virulence of biofilms in various bacterial species</p>Fórmula:C20H24N10O14P2Pureza:98%Cor e Forma:SolidPeso molecular:690.41Edasalonexent
CAS:Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.Fórmula:C31H42N2O3Pureza:99.13% - >99.99%Cor e Forma:SolidPeso molecular:490.68AMT hydrochloride
CAS:<p>AMT hydrochloride is an iNOS inhibitor.</p>Fórmula:C5H11ClN2SPureza:98%Cor e Forma:SolidPeso molecular:166.67(R)-MALT1-IN-3
CAS:<p>(R)-MALT1-IN-3 (121) inhibits MALT1 protease (IC50: 20 nM) and IL6/IL10 in OCI-LY3 (IC50: 60/40 nM).</p>Fórmula:C21H19F3N8O2Cor e Forma:SolidPeso molecular:472.42COX-2-IN-20
CAS:<p>COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].</p>Fórmula:C11H9ClFN3O2Cor e Forma:SolidPeso molecular:269.66APC-0576
CAS:<p>APC-0576, an (S,S)-isomer, blocks NF-kappaB gene activation and may reduce inflammation in human cells.</p>Fórmula:C23H27N3O3Cor e Forma:SolidPeso molecular:393.48ARV-393
CAS:<p>ARV-393 is a PROTAC degrader targeting BCL6 orally available. ubiquitin proteasome for diffuse large b-cell lymphoma (DLBCL) and non-Hodgkin's lymphoma (NHL)</p>Fórmula:C46H53ClFN9O7Pureza:99.96%Cor e Forma:SoildPeso molecular:898.42DDX3-IN-2
CAS:<p>DDX3-IN-2 is a potent DDX3 inhibitor with an IC50 of 0.3 μM and shows broad antiviral effects, including against HIV resistance.</p>Fórmula:C20H23N5OCor e Forma:SolidPeso molecular:349.43Antiviral agent 14
CAS:<p>Antiviral agent 14 is an antiviral agent that inhibits tobacco mosaic virus (TMV) (EC50: 135.5 μg/mL), and cucumber mosaic virus (CMV) (EC50: 178.6 μg/mL).</p>Fórmula:C24H26O7Cor e Forma:SolidPeso molecular:426.46TRAF-STOP inhibitor 6877002
CAS:<p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>Fórmula:C17H17NOPureza:99.76%Cor e Forma:SolidPeso molecular:251.32Mivotilate
CAS:<p>Mivotilate, a potent, non-toxic aryl hydrocarbon receptor (AhR) activator, functions as a hepatoprotective agent.</p>Fórmula:C12H14N2O3S3Pureza:98%Cor e Forma:SolidPeso molecular:330.45Emlenoflast
CAS:Emlenoflast (MCC7840) is a selective inhibitor of NLRP3 inflammasome.Fórmula:C19H24N4O3SPureza:97.004% - 98.19%Cor e Forma:SolidPeso molecular:388.48MIF-IN-2
CAS:MIF-IN-2 is a MIF inhibitor with anticancer activity for the study of cancer and autoimmune diseases.Fórmula:C14H10ClN3O4Pureza:98.55%Cor e Forma:SolidPeso molecular:319.7AZD8848
CAS:AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.Fórmula:C29H43N7O5Cor e Forma:SolidPeso molecular:569.7TLR7 agonist 1
CAS:TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).Fórmula:C21H25N5OPureza:98%Cor e Forma:SolidPeso molecular:363.46TLR7/8 agonist 6
CAS:<p>Compound 4: Imidazoquinoline, potent TLR7/8 agonist, IC50: 0.18μM (TLR7), 5.34μM (TLR8).</p>Fórmula:C24H27N5O2Cor e Forma:SolidPeso molecular:417.5TMV-IN-1
CAS:<p>TMV-IN-1: a chalcone inhibits TMV with EC50s of 70.7 and 60.8 μg/mL, applicable in infection and tumor studies.</p>Fórmula:C28H26O4Cor e Forma:SolidPeso molecular:426.5AR-C102222 hydrochloride
CAS:AR-C102222 hydrochloride: oral iNOS inhibitor, selective, IC50=37 nM, with anti-inflammatory and pain relief effects.Fórmula:C19H17ClF2N6OPureza:98%Cor e Forma:SolidPeso molecular:418.83


