Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(62 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3055 produtos de "Imunologia e Inflamação"
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CYPMPO
CAS:<p>CYPMPO traps hydroxyl/superoxide radicals; decays in UV/H2O2 (15min) & hypoxanthine/xanthine (51min); outperforms DEPMPO in stability & shelf-life.</p>Fórmula:C10H18NO4PCor e Forma:SolidPeso molecular:247.23Naproxen etemesil
CAS:<p>Naproxen, a COX-1/2 inhibitor, has IC50s of 8.72/5.15 μM. Its prodrug, naproxen etemesil, is lipophilic and converts to active form upon absorption.</p>Fórmula:C17H20O5SPureza:98%Cor e Forma:SolidPeso molecular:336.4TL8-506
CAS:<p>TL8-506 is a selective and potent TLR8 agonist that induces cytokine and chemokine production.TL8-506 alleviates inflammatory and autoimmune diseases.</p>Fórmula:C20H17N3O2Pureza:95% - 99.97%Cor e Forma:SolidPeso molecular:331.37NF-κB-IN-3
CAS:<p>NF-κB-IN-3 (Compound 2) is an NF-κB inhibitor (IC50: 0.70 μM) and can be used as an anti-tumour agent.</p>Fórmula:C24H18ClF3N2O2Cor e Forma:SolidPeso molecular:458.86CD73-IN-9
CAS:<p>CD73-IN-9, a potent inhibitor of CD73, may treat cancer by blocking adenosine production that aids tumor growth and spread.</p>Fórmula:C14H11F2N5O2Cor e Forma:SolidPeso molecular:319.27BSP16
CAS:<p>BSP16: potent, oral STING agonist; boosts interferon genes; promising for cancer research.</p>Fórmula:C16H18O5SeCor e Forma:SolidPeso molecular:369.27Imupedone
CAS:Imupedone (LF 1695) is a synthetic immunomodulator that increases the proliferative response of lymphocytes to mitogens, antigens and allogeneic cells.Fórmula:C19H21ClN2OPureza:99.53%Cor e Forma:SolidPeso molecular:328.84ML388
CAS:<p>ML388 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.</p>Fórmula:C20H24N4Pureza:98%Cor e Forma:SolidPeso molecular:320.43NPD926
CAS:<p>NPD926 is an inducer of cancel cell death.</p>Fórmula:C29H35ClN2O2Cor e Forma:SolidPeso molecular:479.05DPP-4 inhibitor 3
CAS:<p>DPP-4 inhibitor 3 is a powerful DPP-IV blocker with 0.75 nM IC50, boasting antioxidant and insulinotropic effects.</p>Fórmula:C19H22N6O2Cor e Forma:SolidPeso molecular:366.42NOD2 antagonist 1
CAS:<p>NOD2 antagonist 1 (compound 32): Selective, effective (IC50: 5.23μM), blocks MDP-induced IL-8 in THP-1, IL-6/IL-10/TNF-α in PBMCs.</p>Fórmula:C26H26N4O3SCor e Forma:SolidPeso molecular:474.57Stigmane B
<p>Stigmane B activates Nrf2, decreases apoptosis and ROS, boosts antioxidants, and is neuroprotective.</p>Fórmula:C21H30O4Cor e Forma:SolidPeso molecular:346.46L-Nabe
CAS:<p>L-Nabe (H-Arg(NO2)-Obzl) is a effective irreversible endothelium dependent relaxation inhibitor.</p>Fórmula:C13H19N5O4Pureza:98.03%Cor e Forma:SolidPeso molecular:309.32Interleukin 1β
CAS:<p>Interleukin 1beta is a bioactive chemical.</p>Fórmula:C15H28N4O5Pureza:98%Cor e Forma:SolidPeso molecular:344.41STING Agonist C11
CAS:<p>STING agonist C11 activates STING, induces type I IFN in cells, phosphorylates IRF3, and lowers various viral titers via STING/IFNAR pathway.</p>Fórmula:C19H18N4O3SCor e Forma:SolidPeso molecular:382.44COX-2-IN-21
CAS:<p>COX-2-IN-21 (Compound 5c) is an orally active, selective COX-2 inhibitor (IC50: 0.039 μM). COX-2-IN-21 has good anti-inflammatory potential.</p>Fórmula:C21H22N6O4Cor e Forma:SolidPeso molecular:422.443-OH-Kynurenamine dihydroiodide
CAS:<p>3-OH-Kynurenamine dihydroiodide, the dihydroiodide form of 3-OH-Kynurenamine, functions as an activator of the aryl hydrocarbon receptor (AhR), thereby modulating the immune response. It enhances the expression of Ido1 and Tgfb1, reducing skin inflammation in psoriasis mouse models and kidney damage in nephrotoxic lupus mouse models .</p>Fórmula:C9H14I2N2O2Cor e Forma:SolidPeso molecular:436.03Dibenzo(a,i)pyrene
CAS:<p>Dibenzo(a, i)pyrene is a polycyclic aromatic hydrocarbon with potent carcinogenic activity.</p>Fórmula:C24H14Cor e Forma:Greenish-Yellow Needles Prisms Or Lamellae Dibenz[A I]Pyrene Is A Colorless Solid Water InsolublePeso molecular:302.37BI605906
CAS:<p>BI605906 is an IKKβ inhibitor that can be used to study inflammatory skin diseases such as psoriasis.</p>Fórmula:C17H22F2N4O3S2Pureza:97.14%Cor e Forma:SolidPeso molecular:432.51COX/5-LOX-IN-1
CAS:<p>Compound 6b is a potent dual inhibitor of COX/5-LOX with IC50s: 1.07μM (COX-1), 0.55μM (COX-2), 0.28μM (5-LOX) for inflammation research.</p>Fórmula:C18H30O3Cor e Forma:SolidPeso molecular:294.43DHMEQ racemate
CAS:<p>DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ.</p>Fórmula:C13H11NO5Pureza:98%Cor e Forma:SolidPeso molecular:261.23MIP-1095
CAS:MIP-1095 is the prostate-specific membrane antigen inhibitor.Fórmula:C19H25IN4O8Pureza:98%Cor e Forma:SolidPeso molecular:564.33HE 3286
CAS:<p>Triolex, an NF-kB inhibitor, is used potentially for the treatment of rheumatoid arthritis, ulcerative colitis.</p>Fórmula:C21H30O3Cor e Forma:SolidPeso molecular:330.46IACS-8803
CAS:<p>IACS-8803 is a potent cyclic dinucleotide STING agonist that exhibits strong systemic antitumor efficacy.</p>Fórmula:C20H23FN10O9P2S2Pureza:98%Cor e Forma:SolidPeso molecular:692.53NIC-0102
CAS:<p>NIC-0102 is an orally active proteasome inhibitor (pIC50:7.55) that exhibits specific inhibition of NLRP3 inflammatory vesicle activation. Inhibitory effect.</p>Fórmula:C21H25BF2N2O4Cor e Forma:SolidPeso molecular:418.24NOC-5
CAS:<p>NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.</p>Fórmula:C6H16N4O2Pureza:98%Cor e Forma:SolidPeso molecular:176.22IL-1β-IN-2
CAS:<p>IL-1β-IN-2, a cannabigerol derivative, serves as a potent inhibitor of IL-1β, exhibiting anti-inflammatory and pain-resolving properties [1].</p>Fórmula:C22H34O2Cor e Forma:SolidPeso molecular:330.5SARS-CoV-2 nsp13-IN-1
CAS:<p>SARS-CoV-2 nsp13-IN-1 (C1) inhibits nsp13 ssDNA+ATPase (IC50: 6 μM), not ssDNA-ATPase; useful for COVID-19 research.</p>Fórmula:C27H20N4O2Pureza:99.44%Cor e Forma:SolidPeso molecular:432.47CHS-111
CAS:<p>CHS-111 is a benzyl indazole that inhibits O2- generation, fMLP-induced PLD activity (IC50 3.9μM), and disrupts PLD1/Arf6 and RhoA interactions.</p>Fórmula:C21H18N2OPureza:98%Cor e Forma:SolidPeso molecular:314.38UC-1V150
CAS:<p>UC-1V150: TLR7 agonist, triggers immune response, anti-tumor, precursor for ISAC synthesis.</p>Fórmula:C16H17N5O4Cor e Forma:SolidPeso molecular:343.34MALT1-IN-8
CAS:<p>MALT1-IN-8: potent MALT1 inhibitor, IC50=2 nM; hinders OCI-LY3 cells, IC50=1.16 μM; anticancer, from patent WO2018165385A1.</p>Fórmula:C20H15Cl2N7OCor e Forma:SolidPeso molecular:440.29U-83836E
CAS:<p>U-83836E (lazaroid ) Possesses neuroprotective activity and anti-tumor activity, inhibits tumor necrosis factor and reverses endotoxin-induced shock.</p>Fórmula:C30H46Cl2N6O2Pureza:99.33%Cor e Forma:SolidPeso molecular:593.63(-)-Ibuprofenamide
CAS:(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity.Fórmula:C13H19NOPureza:98%Cor e Forma:SolidPeso molecular:205.3Nrf2-Activator-12G
CAS:<p>Nrf2-Activator-12G is a potent Nrf-2 activator.</p>Fórmula:C15H13ClO3SPureza:98%Cor e Forma:SolidPeso molecular:308.78Carboxyamidotriazole
CAS:<p>Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways.</p>Fórmula:C17H12Cl3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:424.67ADU-S100 ammonium salt
CAS:<p>ADU-S100 ammonium salt is an activator of stimulator of interferon genes (STING).Cost-effective and quality-assured.</p>Fórmula:C20H30N12O10P2S2Pureza:98%Cor e Forma:SolidPeso molecular:724.6AZD5718
CAS:<p>AZD5718: potent FLAP inhibitor (IC50=2.0 nM), treats Coronary Artery Disease, >90% leukotriene suppression, safe in animal studies, in phase 2a trial.</p>Fórmula:C29H34N6O4Cor e Forma:SolidPeso molecular:530.62Ppc-1
CAS:<p>Ppc-1 inhibits Porphyromonas gingivalis, uncouples mitochondria, and blocks IL-2, with anti-obesity, antibacterial, anti-inflammatory effects.</p>Fórmula:C21H25NO4Pureza:98%Cor e Forma:SolidPeso molecular:355.43YS-121
CAS:<p>YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).</p>Fórmula:C20H26ClN3O2SCor e Forma:SolidPeso molecular:407.96NBC 6
CAS:<p>NLRP3-IN-NBC6: potent NLRP3 inflammasome inhibitor, IC50 574 nM, Ca2+ independent, inhibits inflammasome in THP-1 cells/BMDMs.</p>Fórmula:C18H16BCl3N2O2Cor e Forma:SolidPeso molecular:409.5Hetrombopag
CAS:<p>Hetrombopag: potent thrombopoietin receptor agonist, well tolerated, safe, promising for immune thrombocytopenia research.</p>Fórmula:C25H22N4O5Cor e Forma:SolidPeso molecular:458.47Heme Oxygenase-1-IN-1 hydrochloride
CAS:HO-1-IN-1 hydrochloride is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).Fórmula:C13H16BrClN2Cor e Forma:SolidPeso molecular:315.64Anti-inflammatory agent 1
CAS:<p>Anti-inflammatory agent 1 is an anti-inflammatory compound.</p>Fórmula:C17H16O3SPureza:98%Cor e Forma:SolidPeso molecular:300.37STING ligand-1
CAS:<p>STING ligand-1 is a lead STING ligand(IC50 of 68 nM for HAQ STING).</p>Fórmula:C29H27ClFNO5Pureza:98%Cor e Forma:SolidPeso molecular:523.98Anti-inflammatory agent 8
CAS:<p>Anti-inflammatory agent 8 targets COX-2 over COX-1, IC50 of 0.09 nM, orally bioavailable.</p>Fórmula:C18H15N5OS2Cor e Forma:SolidPeso molecular:381.47iNOS-IN-2
CAS:<p>iNOS-IN-2 (Compound 53) is a potent inducible nitric oxide synthase (iNOS) protein down-regulator.</p>Fórmula:C25H31NO7Cor e Forma:SolidPeso molecular:457.52NOS1-IN-1
CAS:<p>NOS1-IN-1: selective, potent nNOS inhibitor (Ki: 120 nM), less effective on eNOS/iNOS, for neurological disorder research.</p>Fórmula:C14H24F9N7O8Pureza:99.7%Cor e Forma:SolidPeso molecular:589.37Tenosal
CAS:<p>Tenosal obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid, and with analgesic and antipyretic properties, anti-inflammatory.</p>Fórmula:C12H8O4SPureza:98%Cor e Forma:SolidPeso molecular:248.25FK-330 dihydrate
CAS:<p>FK-330 dihydrate (FR-260330 dihydrate), as a NOS inhibitor, prevents tissue damage caused by ischemia and reperfusion. Cost-effective and quality-assured.</p>Fórmula:C29H32ClF3N6O6Pureza:99.52% - 99.98%Cor e Forma:SolidPeso molecular:653.05COX-2-IN-14
CAS:<p>COX-2-IN-14 (2a) is a potent, selective COX-2 inhibitor with high affinity and notable anti-inflammatory effects in mice.</p>Fórmula:C18H18N4O6Cor e Forma:SolidPeso molecular:386.364Bifenazate
CAS:<p>Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.</p>Fórmula:C17H20N2O3Pureza:99.62%Cor e Forma:Solid CrystallinePeso molecular:300.35N-α-Tosyl-L-lysine chloromethyl ketone hydrochloride
CAS:<p>N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride inhibits trypsin-like proteases and IFN-γ activities.</p>Fórmula:C14H22Cl2N2O3SPureza:97.44%Cor e Forma:PowderPeso molecular:369.31Prostaglandin G/H synthase 1 inhibitor
CAS:<p>Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.</p>Fórmula:C13H11ClN2OPureza:99.76%Cor e Forma:SolidPeso molecular:246.69MIF-IN-6
CAS:<p>MIF-IN-6 is a potent MIF inhibitor with IC50 1.4 μM, Ki 0.96 μM, and hinders A549 cell growth.</p>Fórmula:C18H13ClFN5O2Cor e Forma:SolidPeso molecular:385.78COX/5-LO-IN-1
CAS:<p>COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.</p>Fórmula:C16H15FN2O2SPureza:98%Cor e Forma:SolidPeso molecular:318.37Isonixin
CAS:<p>Isonixin is used for the treatment of inflammation and pain associated with musculoskeletal and joint disorders.</p>Fórmula:C14H14N2O2Pureza:98%Cor e Forma:SolidPeso molecular:242.27Thiazolinobutazone
CAS:<p>Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.</p>Fórmula:C22H26N4O2SCor e Forma:SolidPeso molecular:410.53NRP1 antagonist 2
CAS:<p>NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.</p>Fórmula:C20H17ClN6OS2Cor e Forma:SolidPeso molecular:456.97CID-2858522
CAS:<p>CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).</p>Fórmula:C28H39N3O3Pureza:96.12%Cor e Forma:SolidPeso molecular:465.63TBK1/IKKε-IN-4
CAS:<p>TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nM</p>Fórmula:C28H35N7O4Cor e Forma:SolidPeso molecular:533.627-NINA
CAS:non-selective NOS inhibitorFórmula:C7H5N3NaO2Pureza:98%Cor e Forma:SolidPeso molecular:186.12LY 178002
CAS:<p>LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.</p>Fórmula:C18H25NO2SPureza:98%Cor e Forma:SolidPeso molecular:319.46Propoxur
CAS:<p>Propoxur: an insecticide causing temporary cholinergic effects in humans; chronic exposure leads to health issues; carcinogenicity unclassified by EPA.</p>Fórmula:C11H15NO3Pureza:99.84% - 99.87%Cor e Forma:Minute Crystals (Niosh 2016)Peso molecular:209.24GSK319347A
CAS:<p>GSK319347A is a dual inhibitor of TBK1 and IKKε that inhibits IKK2 and can be used to study bladder and lung adenocarcinomas.</p>Fórmula:C22H19N3O5S2Pureza:98.42%Cor e Forma:SolidPeso molecular:469.53R110
CAS:<p>R110 shows the potential for cancer research that is a potent, competitive MIF2 tautomerase inhibitor (IC 50 = 15 μM) [1].</p>Fórmula:C15H17ClN2OSCor e Forma:SolidPeso molecular:308.83MALT1-IN-3
CAS:<p>MALT1-IN-3 is a potent inhibitor of MALT1 protease (IC50: 0.06 μM) with IC50 values of 0.14 and 0.13 μM for human IL6 and IL10, respectively, in OCI-LY3 cells.</p>Fórmula:C21H19F3N8O2Cor e Forma:SolidPeso molecular:472.42Naproxen glucuronide
CAS:<p>Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.</p>Fórmula:C20H22O9Cor e Forma:SolidPeso molecular:406.38MK-0703
CAS:<p>MK-0703 is a selective cyclooxygenase-2 inhibitor.</p>Fórmula:C17H22O5SPureza:98%Cor e Forma:SolidPeso molecular:338.42Tilarginine
CAS:<p>Tilarginine is a nitric oxide synthetase competitive inhibitor.</p>Fórmula:C7H16N4O2Pureza:98%Cor e Forma:SolidPeso molecular:188.23CHD-5
CAS:<p>CHD-5 is a selective antagonist of the aryl hydrocarbon receptor (AhR).</p>Fórmula:C19H17N3O2Cor e Forma:SolidPeso molecular:319.36Insulin levels modulator
CAS:Insulin level regulators can be used to treat diabetes.Fórmula:C21H23N7OSPureza:98%Cor e Forma:SolidPeso molecular:421.52MitoTEMPOL
CAS:<p>MitoTEMPOL is a mitochondria-targeted antioxidant that prevents septal dysfunction by reversing sepsis-induced decreases in mitochondrial function.</p>Fórmula:C32H42BrNO2PCor e Forma:SolidPeso molecular:583.56NLRP3-IN-13
CAS:<p>NLRP3-IN-13 is an NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.</p>Fórmula:C19H15N3O3SPureza:99.16%Cor e Forma:SolidPeso molecular:365.41COX-2/5-LOX-IN-1
CAS:<p>COX-2/5-LOX-IN-1, a benzothiophen-2-yl pyrazole, inhibits COX-2 & 5-LOX with IC50: COX-1 (12.13μM), COX-2 (0.4μM), 5-LOX (4.96μM). Better than Celecoxib.</p>Fórmula:C14H10ClN3O4S2Cor e Forma:SolidPeso molecular:383.83ND-2110
CAS:<p>ND-2110, a selective interleukin-1 receptor-associated kinase 4 inhibitors, is used for the treatment of autoimmune disorders and lymphoid malignancy.</p>Fórmula:C21H28N4O3SCor e Forma:SolidPeso molecular:416.54IKKβ-IN-1
CAS:<p>IKKβ-IN-1 is a potent, orally active inhibitor of IkappaB (IKK-β) (IC50: 0.20 μM).</p>Fórmula:C31H30N4O4SCor e Forma:SolidPeso molecular:554.66MIND4-17
CAS:<p>MIND4-17 activates NRF2 by binding Keap1 C151, blocking Keap1-Nrf2, stabilizes Nrf2, and promotes its nuclear entry, with strong antioxidant effects.</p>Fórmula:C20H15N5O3SCor e Forma:SolidPeso molecular:405.43IRAK4-IN-21
CAS:<p>IRAK4-IN-21: Oral IRAK4 inhibitor, IC50: IRAK4 5 nM, TAK1 56 nM; curbs IL-23, aids autoimmune research.</p>Fórmula:C28H28FN7O2Cor e Forma:SolidPeso molecular:513.57Isocyclosporin A
CAS:<p>Isocyclosporin A is a rearranged degradation product. It is formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.</p>Fórmula:C62H111N11O12Cor e Forma:SolidPeso molecular:1202.61PC407-ws
CAS:<p>PC407-ws is a water-soluble novel COX-2 inhibitor.</p>Fórmula:C24H18F3N3Na2O5SPureza:98%Cor e Forma:SolidPeso molecular:563.46IRAK4-IN-22
CAS:<p>IRAK4-IN-22: oral IRAK4 inhibitor, IC50: IRAK4-3nM, TAK1-17nM, disrupts IL-23, targets autoimmune diseases.</p>Fórmula:C28H28FN7O2Cor e Forma:SolidPeso molecular:513.57AHR antagonist 5
CAS:<p>Potent, oral AHR blocker from WO2018195397; IC50 < 0.5μM; hinders tumor growth with anti-PD-1.</p>Fórmula:C25H27Cl3FN7Pureza:98%Cor e Forma:SolidPeso molecular:550.89RWJ 63556
CAS:RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.Fórmula:C11H10FNO3S2Pureza:99.92%Cor e Forma:SolidPeso molecular:287.33Oxyphenbutazone monohydrate
CAS:<p>Oxyphenbutazone monohydrate: Phenylbutazone derivative, anti-inflammatory, non-selective COX inhibitor, kills dormant M. tuberculosis.</p>Fórmula:C19H22N2O4Cor e Forma:SolidPeso molecular:342.39Nrf2 activator-3
CAS:Nrf2 activator-3 is an Nrf2 activator with potential anti-inflammatory, antioxidant and anti-tumor activity for the study of neurological diseases.Fórmula:C23H18F3N3O2Pureza:98.52% - 99.84%Cor e Forma:SolidPeso molecular:425.4NLRP3 antagonist 1
CAS:<p>Potential cancer research drug, NLRP3 antagonist 1, targets immune response in macrophages, neutrophils.</p>Fórmula:C16H18N6OCor e Forma:SolidPeso molecular:310.35Phortress
CAS:<p>Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor</p>Fórmula:C20H25Cl2FN4OSPureza:99.89%Cor e Forma:SolidPeso molecular:459.41MitoB
CAS:<p>MitoB is a novel exon of mitochondrial hydrogen peroxide.</p>Fórmula:C25H23BBrO2PCor e Forma:SolidPeso molecular:477.14CU-76
CAS:<p>CU-76 inhibits cGAS (IC50 = 0.24 μM) affecting DNA-induced IFN-β production, not RIG-I-MAVS pathway, in THP-1 cells.</p>Fórmula:C11H8F2IN5O2Cor e Forma:SolidPeso molecular:407.11Heterophdoid A
CAS:<p>Heterophdoid A is an anti-inflammatory agent that inhibits NO production in BV-2 cells (IC50: 5.93 μM).</p>Fórmula:C26H42O10Cor e Forma:SolidPeso molecular:514.61Ruzotolimod
CAS:<p>Ruzotolimod, an agonist of TLR7, exhibits promising potential for investigating HBV, COVID-19, and SARS-CoV-2 infections （WO2021130195A1）[1].</p>Fórmula:C14H18N4O5SCor e Forma:SolidPeso molecular:354.38MHY884
CAS:<p>MHY884 inhibits tyrosinase and UVB-triggered NF-κB activation by reducing oxidative stress.</p>Fórmula:C15H14ClNO3SPureza:98%Cor e Forma:SolidPeso molecular:323.79COX-2-IN-26
CAS:<p>COX-2-IN-26: Oral, selective COX-2 inhibitor, low IC50s; anti-inflammatory with GI safety.</p>Fórmula:C23H21N7OS3Cor e Forma:SolidPeso molecular:507.65COX-2/15-LOX-IN-1
CAS:<p>COX-2/15-LOX-IN-1 is a dual inhibitor for COX-2/15-LOX with anti-inflammatory properties (IC50: COX-1 10.65μM, COX-2 0.075μM, 15-LOX 2.98μM).</p>Fórmula:C21H21N7S3Cor e Forma:SolidPeso molecular:467.63GCPII-IN-1 TFA
CAS:<p>GCPII-IN-1 TFA (compound 2) is an inhibitor scaffold for glutamate carboxypeptidase II (GCPII, PSMA) with a Ki of 44.3±2.4 nM for use in prostate cancer.</p>Fórmula:C14H22F3N3O9Cor e Forma:SoildPeso molecular:433.34QD-394
CAS:<p>QD-394 promotes ROS, impairs GSH/GSSG ratio, and is cytotoxic to pancreatic cancer cells, with synergy with napabucasin.</p>Fórmula:C19H19N5O2Cor e Forma:SolidPeso molecular:349.39COX-2-IN-16
CAS:<p>COX-2-IN-16: potent, selective oral COX-2 blocker, IC50=102 μM, reduces NO, anti-inflammatory.</p>Fórmula:C19H12BrN3O2Cor e Forma:SolidPeso molecular:394.22hDDAH-1-IN-1 TFA
CAS:<p>hDDAH-1-IN-1 TFA is a selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) (Ki: 18 μM).</p>Fórmula:C12H22F6N4O5Pureza:98%Cor e Forma:SolidPeso molecular:416.32NCX 466
CAS:<p>cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor</p>Fórmula:C20H24N2O9Pureza:98%Cor e Forma:SolidPeso molecular:436.41Clopirac
CAS:<p>Clopirac is a potent and orally active prostaglandin synthetase inhibitor that is an anti-inflammatory agent [1].</p>Fórmula:C14H14ClNO2Cor e Forma:SolidPeso molecular:263.72
