Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(63 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3054 produtos de "Imunologia e Inflamação"
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CU-76
CAS:<p>CU-76 inhibits cGAS (IC50 = 0.24 μM) affecting DNA-induced IFN-β production, not RIG-I-MAVS pathway, in THP-1 cells.</p>Fórmula:C11H8F2IN5O2Cor e Forma:SolidPeso molecular:407.11Oxyphenbutazone monohydrate
CAS:<p>Oxyphenbutazone monohydrate: Phenylbutazone derivative, anti-inflammatory, non-selective COX inhibitor, kills dormant M. tuberculosis.</p>Fórmula:C19H22N2O4Cor e Forma:SolidPeso molecular:342.39GSK319347A
CAS:<p>GSK319347A is a dual inhibitor of TBK1 and IKKε that inhibits IKK2 and can be used to study bladder and lung adenocarcinomas.</p>Fórmula:C22H19N3O5S2Pureza:98.42%Cor e Forma:SolidPeso molecular:469.53LY 178002
CAS:<p>LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.</p>Fórmula:C18H25NO2SPureza:98%Cor e Forma:SolidPeso molecular:319.46ADU-S100 ammonium salt
CAS:<p>ADU-S100 ammonium salt is an activator of stimulator of interferon genes (STING).Cost-effective and quality-assured.</p>Fórmula:C20H30N12O10P2S2Pureza:98%Cor e Forma:SolidPeso molecular:724.6MitoTEMPOL
CAS:<p>MitoTEMPOL is a mitochondria-targeted antioxidant that prevents septal dysfunction by reversing sepsis-induced decreases in mitochondrial function.</p>Fórmula:C32H42BrNO2PCor e Forma:SolidPeso molecular:583.56NLRP3-IN-13
CAS:<p>NLRP3-IN-13 is an NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.</p>Fórmula:C19H15N3O3SPureza:99.16%Cor e Forma:SolidPeso molecular:365.41GCPII-IN-1 TFA
CAS:<p>GCPII-IN-1 TFA (compound 2) is an inhibitor scaffold for glutamate carboxypeptidase II (GCPII, PSMA) with a Ki of 44.3±2.4 nM for use in prostate cancer.</p>Fórmula:C14H22F3N3O9Cor e Forma:SoildPeso molecular:433.34JAK2/STAT3-IN-1
CAS:<p>JAK2/STAT3-IN-1 is a GP130 inhibitor with anti-tumor effects and can be used to study inflammation, autoimmunity and cancer.</p>Fórmula:C34H35BrF3N5O2Pureza:97.35%Cor e Forma:SolidPeso molecular:682.57WIN 54954
CAS:<p>WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and may be used in the study of small ribonucleic acid virus infections.</p>Fórmula:C18H20Cl2N2O3Pureza:98.98%Cor e Forma:SolidPeso molecular:383.27SNAP 398299
CAS:<p>SNAP 398299 is a Glycopeptide Receptor Type 3 (Gal3) antagonist with anxiolytic and antidepressant-like effects and is used in the study of mood disorders.</p>Fórmula:C27H24F3N3O2Pureza:97.16%Cor e Forma:SolidPeso molecular:479.49KIN1400
CAS:<p>KIN1400 activates IRF3, boosts antiviral immunity, stimulates IFNbeta, and inhibits WNV, DV, and HCV.</p>Fórmula:C24H17F2N3O2SPureza:98%Cor e Forma:SolidPeso molecular:449.47ARV-393
CAS:<p>ARV-393 is a PROTAC degrader targeting BCL6 orally available. ubiquitin proteasome for diffuse large b-cell lymphoma (DLBCL) and non-Hodgkin's lymphoma (NHL)</p>Fórmula:C46H53ClFN9O7Pureza:99.96%Cor e Forma:SoildPeso molecular:898.42DDX3-IN-2
CAS:<p>DDX3-IN-2 is a potent DDX3 inhibitor with an IC50 of 0.3 μM and shows broad antiviral effects, including against HIV resistance.</p>Fórmula:C20H23N5OCor e Forma:SolidPeso molecular:349.43TRAF-STOP inhibitor 6877002
CAS:<p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>Fórmula:C17H17NOPureza:99.76%Cor e Forma:SolidPeso molecular:251.32MIF-IN-2
CAS:<p>MIF-IN-2 is a MIF inhibitor with anticancer activity for the study of cancer and autoimmune diseases.</p>Fórmula:C14H10ClN3O4Pureza:98.55%Cor e Forma:SolidPeso molecular:319.7UC-781
CAS:<p>UC-781, a potent NNRTI, inhibits HIV-1 with a C50 of 5 nM and is stable across pH and temperatures.</p>Fórmula:C17H18ClNO2SPureza:92.17%Cor e Forma:SolidPeso molecular:335.85CD73-IN-1
CAS:CD73-IN-1 is a CD73 inhibitor with anticancer activity.Fórmula:C18H17N3O4SPureza:99.46% - 99.46%Cor e Forma:SolidPeso molecular:371.41OXSI-2
CAS:<p>OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.</p>Fórmula:C18H15N3O3SPureza:98%Cor e Forma:Dark Orange SolidPeso molecular:353.39CK-119
CAS:<p>CK-119 inhibits IL-1, blocking corneal/conjunctival cell growth by halting DNA/RNA synthesis.</p>Fórmula:C21H23ClN4O5Cor e Forma:SolidPeso molecular:446.88MIF-IN-3
CAS:<p>MIF-IN-3 inhibits MIF; useful in immunoinflammation research. (WO2021258272A1, compound 31)</p>Fórmula:C20H20N4O5SCor e Forma:SolidPeso molecular:428.46BBS-4
CAS:<p>BBS-4 inhibits NOS2 dimerization (IC50: 0.49 nM), guarding mice against sepsis-related heart issues.</p>Fórmula:C22H24N6O3Cor e Forma:SolidPeso molecular:420.46HSR1304
CAS:<p>HSR1304 (5d) inhibits NFκB, key in diseases like cancer, offering research potential.</p>Fórmula:C24H21ClN2O3Cor e Forma:SolidPeso molecular:420.89Anti-inflammatory agent 21
CAS:<p>Compound 9o: orally active, low-toxicity anti-inflammatory; inhibits NO (IC50: 0.76 μM), blocks NF-κB/MAPK, reduces arthritis symptoms.</p>Fórmula:C24H21FO6Cor e Forma:SolidPeso molecular:424.42Fc 11a-2
CAS:<p>Fc 11a-2, an oral benzimidazole, potently inhibits NLRP3 inflammasome and caspase-1 to prevent colitis.</p>Fórmula:C16H16N2Cor e Forma:SolidPeso molecular:236.31COX-2-IN-22
CAS:<p>COX-2-IN-22 inhibits COX-2 (IC50: 8.6μM) and crosses the blood-brain barrier, also affects AChE, BChE, β-Secretase, LOX-5, DPPH.</p>Fórmula:C29H24O7Cor e Forma:SolidPeso molecular:484.5NBC 19
CAS:<p>Potent NLRP3 inflammasome inhibitor (IC50 = 60-80 nM). Inhibits nigericin- and ATP-induced IL-1β release.</p>Fórmula:C24H26BCl3N2O2Cor e Forma:SolidPeso molecular:491.65TNF-α-IN-18
CAS:<p>TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.</p>Fórmula:C16H7ClF2O4Pureza:99.77%Cor e Forma:SolidPeso molecular:336.67Simvastatin acid calcium hydrate
CAS:<p>Simvastatin (Tenivastatin) calcium hydrate is an oral HMG-CoA reductase inhibitor that reduces ROS by blocking indoxyl sulfate.</p>Fórmula:C25H40O6Cor e Forma:SolidPeso molecular:436.28249AR-C 102222
CAS:<p>AR-C 102222 is an iNOS inhibitor.</p>Fórmula:C19H16F2N6OPureza:98%Cor e Forma:SolidPeso molecular:382.37Stigmane B
<p>Stigmane B activates Nrf2, decreases apoptosis and ROS, boosts antioxidants, and is neuroprotective.</p>Fórmula:C21H30O4Cor e Forma:SolidPeso molecular:346.46Indolokine A5
CAS:<p>Indolokine A5, a catabolite of L-cysteine, is a potent AhR agonist .</p>Fórmula:C13H8N2O3SCor e Forma:SolidPeso molecular:272.28Dibenzo(a,i)pyrene
CAS:<p>Dibenzo(a, i)pyrene is a polycyclic aromatic hydrocarbon with potent carcinogenic activity.</p>Fórmula:C24H14Cor e Forma:Greenish-Yellow Needles Prisms Or Lamellae Dibenz[A I]Pyrene Is A Colorless Solid Water InsolublePeso molecular:302.37COX-2/5-LOX-IN-3
CAS:<p>COX-2/5-LOX-IN-3 inhibits COX-2/5-LOX with IC50s: COX-1 45.73μM, COX-2 5.45μM, 5-LOX 4.33μM; promising for inflammation research.</p>Fórmula:C17H16ClN3O2SCor e Forma:SolidPeso molecular:361.85Pifoxime
CAS:<p>Pifoxime: a NSAID with COX-1/2 inhibition, used in anti-inflammatory treatment and neuropsychiatric studies.</p>Fórmula:C15H20N2O3Cor e Forma:SolidPeso molecular:276.33NOD2 antagonist 1
CAS:<p>NOD2 antagonist 1 (compound 32): Selective, effective (IC50: 5.23μM), blocks MDP-induced IL-8 in THP-1, IL-6/IL-10/TNF-α in PBMCs.</p>Fórmula:C26H26N4O3SCor e Forma:SolidPeso molecular:474.57COX/5-LOX-IN-1
CAS:<p>Compound 6b is a potent dual inhibitor of COX/5-LOX with IC50s: 1.07μM (COX-1), 0.55μM (COX-2), 0.28μM (5-LOX) for inflammation research.</p>Fórmula:C18H30O3Cor e Forma:SolidPeso molecular:294.43Leptospermone
CAS:<p>Leptospermone is an essential oil from Leptospermum scoparium (manuka oil).</p>Fórmula:C15H22O4Cor e Forma:SolidPeso molecular:266.33MIF-IN-6
CAS:<p>MIF-IN-6 is a potent MIF inhibitor with IC50 1.4 μM, Ki 0.96 μM, and hinders A549 cell growth.</p>Fórmula:C18H13ClFN5O2Cor e Forma:SolidPeso molecular:385.78Interleukin 1β
CAS:<p>Interleukin 1beta is a bioactive chemical.</p>Fórmula:C15H28N4O5Pureza:98%Cor e Forma:SolidPeso molecular:344.41CYPMPO
CAS:<p>CYPMPO traps hydroxyl/superoxide radicals; decays in UV/H2O2 (15min) & hypoxanthine/xanthine (51min); outperforms DEPMPO in stability & shelf-life.</p>Fórmula:C10H18NO4PCor e Forma:SolidPeso molecular:247.23AZD5718
CAS:<p>AZD5718: potent FLAP inhibitor (IC50=2.0 nM), treats Coronary Artery Disease, >90% leukotriene suppression, safe in animal studies, in phase 2a trial.</p>Fórmula:C29H34N6O4Cor e Forma:SolidPeso molecular:530.62COX-2-IN-26
CAS:<p>COX-2-IN-26: Oral, selective COX-2 inhibitor, low IC50s; anti-inflammatory with GI safety.</p>Fórmula:C23H21N7OS3Cor e Forma:SolidPeso molecular:507.65MIF-IN-5
CAS:<p>MIF-IN-5: reversible MIF inhibitor, IC50 4.8 μM, Ki 3.3 μM.</p>Fórmula:C18H14FN5O2Cor e Forma:SolidPeso molecular:351.33Nexinhib20
CAS:<p>Nexinhib20 is an inhibitor of exosome synthesis and transport with anti-inflammatory activity, inhibits RAB27A and neutral sphingomyelinase 2 (nSMase2) nsMase2.</p>Fórmula:C15H16N4O3Pureza:99.89%Cor e Forma:SolidPeso molecular:300.31Feprazone
CAS:<p>Feprazone (DA-2370) possesses anti-inflammatory and antiadipogenic properties. Feprazone can be used in studies about the treatment of joint and muscular pain.</p>Fórmula:C20H20N2O2Pureza:99.6% - 99.89%Cor e Forma:SolidPeso molecular:320.3912(R)-HETE
CAS:<p>12(R)-HETE made in invertebrates by lipoxygenation, in mammals by 12(R)-LOs/CYP450. Mainly proinflammatory, attracts leukocytes, reduces rabbit eye pressure.</p>Fórmula:C20H32O3Cor e Forma:SolidPeso molecular:320.47IMD-ferulic
<p>IMD-ferulic, a compound that forms covalent bonds, acts as an NF-κB modulator, enhancing the adjuvanticity of small molecule immune potentiators.</p>Fórmula:C36H41N7O4Cor e Forma:SolidPeso molecular:635.76CPS-11
CAS:<p>CPS-11, a Thalidomide analogue, shows potent, broad antitumor activity, especially in multiple myeloma cells.</p>Fórmula:C14H12N2O5Pureza:99.8% - 99.98%Cor e Forma:SolidPeso molecular:288.26Sonlicromanol hydrochloride
CAS:<p>Sonlicromanol hydrochloride (KH176 hydrochloride) is a ROS-redox modulator used in the treatment of mitochondrial diseases.</p>Fórmula:C19H29ClN2O3Pureza:99.53%Cor e Forma:SolidPeso molecular:368.9Cindunistat
CAS:<p>Cindunistat (free base) is an orally available selective iNOS inhibitor for the study of arthritis.</p>Fórmula:C8H17N3O2SPureza:99% - >99.99%Cor e Forma:SolidPeso molecular:219.3IL-2-IN-1
CAS:IL-2-IN-1 is a potent inhibitor of IL-2 (IC50: 1978 nM) and exhibits anti-proliferative effects.Fórmula:C17H12F6N4O2Pureza:99.6%Cor e Forma:SolidPeso molecular:418.29SM360320
CAS:<p>SM360320 (CL-087) is a selective TLR7 agonist that blocks HCV replication in hepatocytes and aids immunology research.</p>Fórmula:C15H17N5O3Pureza:99.13%Cor e Forma:SolidPeso molecular:315.33F092
CAS:<p>F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases.</p>Fórmula:C20H17N5O2Pureza:99.63%Cor e Forma:SolidPeso molecular:359.38Azalanstat
CAS:<p>Azalanstat (RS 21607) is a mammalian lanosterol 14-alpha-demethylase inhibitor with hypocholesterolemic activity.</p>Fórmula:C22H24ClN3O2SPureza:99.41% - 99.85%Cor e Forma:SolidPeso molecular:429.96Thiodigalactoside
CAS:<p>Thiodigalactoside (TDG), a non-metabolizable disaccharide, serves as an orally active, potent galectin (GAL) inhibitor, exhibiting Kd values of 24 μM and 49 μM</p>Fórmula:C12H22O10SPureza:99.90%Cor e Forma:SolidPeso molecular:358.36h-NTPDase8-IN-1
CAS:h-NTPDase8-IN-1 is a specific aminosulfonylbenzamide inhibitor of h-NTPDases8, which can be used to study diseases caused by aberrant h-NTPDase expression.Fórmula:C10H10ClNO4SPureza:98.78% - 99.59%Cor e Forma:SolidPeso molecular:275.71Ezurpimtrostat hydrochloride
CAS:<p>Ethacrysta hydrochloride (GNS561 hydrochloride) is a PPT1 inhibitor with antifibrotic properties and may be used in studies of hepatocellular carcinoma.</p>Fórmula:C25H32Cl2N4Pureza:99.84%Cor e Forma:SolidPeso molecular:459.45B022
CAS:<p>B022 is an NF-κB-induced kinase (NIK) inhibitor that protects the liver from inflammation and injury caused by oxidative stress and toxins.</p>Fórmula:C19H16ClN5OSPureza:99.74%Cor e Forma:SolidPeso molecular:397.88NDT 9513727
CAS:NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.Fórmula:C36H35N3O4Pureza:99.21%Cor e Forma:SolidPeso molecular:573.68NFATc1-IN-1
CAS:<p>NFATc1-IN-1 (A04) inhibits RANKL-induced osteoclast formation with 1.57 μM IC50, blocking NFATc1 translocation.</p>Fórmula:C13H8F2INO2Pureza:99.64%Cor e Forma:SolidPeso molecular:375.11BBIQ
CAS:<p>BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of 59.1</p>Fórmula:C21H22N4Pureza:99.71%Cor e Forma:SolidPeso molecular:330.43YM-53403
CAS:<p>YM-53403: Antiviral that combats both RSV subgroup A/B, treats respiratory infections.</p>Fórmula:C36H29N3O3SPureza:98.49% - 98.85%Cor e Forma:SolidPeso molecular:583.7LMT-28
CAS:<p>LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2.</p>Fórmula:C17H29NO4Pureza:99.88%Cor e Forma:SolidPeso molecular:311.42T6167923
CAS:<p>T6167923 inhibits MyD88 signaling, binds TIR domain, blocks dimer formation, lowers SEAP activity, and has anti-inflammatory IC50s ~2.7 μM.</p>Fórmula:C17H20BrN3O3S2Pureza:99.28%Cor e Forma:SolidPeso molecular:458.39Resiniferatoxin
CAS:<p>Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist.Cost-effective and quality-assured.</p>Fórmula:C37H40O9Pureza:93.08% - 99.34%Cor e Forma:SolidPeso molecular:628.71Tilomisole
CAS:Tilomisole (Wy 18251) is an oral anti-inflammatory and immunomodulatory benzimidazole thiazole, used in cancer and inflammation research.Fórmula:C17H11ClN2O2SPureza:99.21%Cor e Forma:SolidPeso molecular:342.8Rociclovir
CAS:<p>Rociclovir has antiviral activity and is used to treat viral infections.</p>Fórmula:C15H25N5O3Pureza:99.19%Cor e Forma:SolidPeso molecular:323.39APX-115
CAS:<p>APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4).</p>Fórmula:C17H18ClN3OPureza:98.62%Cor e Forma:SolidPeso molecular:315.8JC124
CAS:<p>JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.</p>Fórmula:C17H19ClN2O4SPureza:99.64%Cor e Forma:SolidPeso molecular:382.86Letosteine
CAS:<p>Letosteine, an oral expectorant, treats acute/chronic respiratory diseases by dissolving mucus and reducing inflammation.</p>Fórmula:C10H17NO4S2Pureza:96.03%Cor e Forma:SolidPeso molecular:279.38R 61837
CAS:<p>R 61837 is a novel rhinovirus inhibitor, a substituted phenylpyridazinamine, with antiviral activity.</p>Fórmula:C16H20N4OPureza:99.53%Cor e Forma:SolidPeso molecular:284.36ABI-1968
CAS:<p>ABI-1968 has antiviral and antitumor activity and can be used to study immune system diseases.</p>Fórmula:C35H58N5O6PPureza:98.54%Cor e Forma:SolidPeso molecular:675.839HS271
CAS:<p>HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM).</p>Fórmula:C21H24F3N5O2Pureza:98.79%Cor e Forma:SolidPeso molecular:435.44Phox-I2
CAS:<p>Phox-I2 is an NOX2-specific inhibitor. Phox-I2 reverts ROS-accumulation and leads to refusion of mitochondrial networks.</p>Fórmula:C18H15N3O4Pureza:99.73%Cor e Forma:SolidPeso molecular:337.33Complement C5-IN-1
CAS:Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).Fórmula:C24H32N2O6Pureza:98.27%Cor e Forma:SolidPeso molecular:444.52Zabedosertib
CAS:<p>Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential.</p>Fórmula:C20H21F3N4O4SPureza:98.54%Cor e Forma:SolidPeso molecular:470.47SC-75416
CAS:SC-75416, a cyclooxygenase-2 (COX-2) inhibitor, is used potentially for the treatment of postoperative inflammation.Fórmula:C15H14ClF3O3Pureza:98.67% - 98.67%Cor e Forma:SolidPeso molecular:334.72NLRP3-IN-10
CAS:<p>NLRP3-IN-10 (ZVN26391) is a strong NLRP3 inhibitor, IC50 251.1 nM, that reduces IL-1β and ASC speck, hindering inflammasome activation.</p>Fórmula:C17H14BrFO3Pureza:99.06%Cor e Forma:SolidPeso molecular:365.19FK-330
CAS:<p>FK-330 (FR-260330) is a novel nitric oxide synthase inhibitor that prevents ischemia and reperfusion injury in rat liver transplantation.</p>Fórmula:C29H28ClF3N6O4Pureza:99.95%Cor e Forma:SolidPeso molecular:617.02CT-2584
CAS:<p>CT-2584: angiogenesis & lysophosphatidic acid transferase inhibitor; alters phospholipid synthesis, increasing PI in tumor cells.</p>Fórmula:C30H55N5O3Pureza:97.68% - 99.77%Cor e Forma:SolidPeso molecular:533.79SP-100030
CAS:SP-100030: Strong NF-κB/AP-1 inhibitor, IC50=50 nM. Reduces IL-2, IL-8, TNF-alpha, and murine CIA.Fórmula:C14H5ClF9N3OPureza:99.79%Cor e Forma:SolidPeso molecular:437.65IRAK4-IN-20
CAS:<p>IRAK4-IN-20 is a potent and orally active IRAK4 inhibitor (IC50:3.55 nM).</p>Fórmula:C22H25F3N4O3Pureza:98.09%Cor e Forma:SolidPeso molecular:450.45NLRP3/AIM2-IN-2
CAS:<p>NLRP3/AIM2-IN-2, potent species-specific NLRP3 and AIM2 inflammasome pyroptosis inhibitor; IC50 = 0.2392 ± 0.0233 μM.</p>Fórmula:C15H15NO3Pureza:99.67%Cor e Forma:SolidPeso molecular:257.28Totrombopag
CAS:<p>Totrombopag (SB559448) is a candidate compound for action on RSV polymerase.</p>Fórmula:C25H22N8O2Pureza:99.50%Cor e Forma:SolidPeso molecular:466.49CPG-52364
CAS:<p>CPG-52364 is a small molecule compound that interacts between an endosomal TLR and its ligand and is a candidate for the treatment of psoriasis.</p>Fórmula:C27H36N6O3Pureza:99.99%Cor e Forma:SolidPeso molecular:492.61ABT-963
CAS:<p>ABT-963: COX-2 inhibitor for osteoarthritis/pain with high selectivity, potency, and gastric safety.</p>Fórmula:C22H22F2N2O5SPureza:98% - 99.85%Cor e Forma:SolidPeso molecular:464.48FEN1-IN-3
CAS:<p>FEN1-IN-3 is a human flap endonuclease-1 ( hFEN1 ) inhibitor that stabilizes hFEN1 with an EC 50 of 6.8 μM .</p>Fórmula:C15H12N2O4Pureza:98.16%Cor e Forma:SolidPeso molecular:284.27Biofor 389
CAS:<p>Biofor 389 (BF389) has anti-inflammatory activity and can be used to study arthritis.</p>Fórmula:C20H29NO3Pureza:98.84% - 99.97%Cor e Forma:SolidPeso molecular:331.45Desmosterol
CAS:<p>Desmosterol (24-Dehydrocholesterol) is a cholesterol biosynthesis intermediate that inhibits macrophage inflammatory vesicle activation .</p>Fórmula:C27H44OPureza:>99.99%Cor e Forma:SolidPeso molecular:384.64M62812
CAS:<p>TLR4 inhibitor blocks LPS-induced NF-κB (IC50=2.4μg/mL), cytokines in PBMCs/HUVECs, and extends life in septic shock mice.</p>Fórmula:C13H13Cl2N3OSPureza:99.07%Cor e Forma:SolidPeso molecular:330.23Zharp2-1
CAS:<p>Zharp2-1 is a RIPK2 inhibitor that alleviates MDP-induced peritonitis symptoms in mice and can be used to study inflammatory bowel disease (IBD).</p>Fórmula:C19H18N3O2PSPureza:99.41%Cor e Forma:SolidPeso molecular:383.4AHR antagonist 2
CAS:<p>AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively.</p>Fórmula:C20H17F3N4O3Pureza:99.38%Cor e Forma:SolidPeso molecular:418.37EIDD-2749
CAS:<p>EIDD-2749 (4'-Fluorouridine), an oral drug, inhibits RdRp, halts RSV/SARS-CoV-2 replication, and fights HCV/LCMV.</p>Fórmula:C9H11FN2O6Pureza:97.39%Cor e Forma:SolidPeso molecular:262.19RIPK1-IN-9
CAS:<p>RIPK1-IN-9, a potent dihydronaphthone, selectively inhibits RIPK1 with IC50 of 2 nM (U937) and 1.3 nM (L929).</p>Fórmula:C26H25FN6O2Pureza:99.85%Cor e Forma:SolidPeso molecular:472.51Rufigallol
CAS:<p>Rufigallol, an anthraquinone with six OH groups, induces DLC and fluoresces when aggregated, showing antimalarial effects with vitamin C and ketones.</p>Fórmula:C14H8O8Pureza:98.92% - 99.27%Cor e Forma:SolidPeso molecular:304.21RIG012
CAS:RIG012 is a potent RIG-I inhibitor with an IC50 value of 0.71 μM measured by NADH-coupled ATPase.RIG012 inhibited the expression of IFN-β and ISG hRsad2.Fórmula:C23H21NO3Pureza:99.48%Cor e Forma:SolidPeso molecular:359.42Epetirimod
CAS:<p>Epetirimod (S-30563) is a small molecule immunomodulator with antitumor and anti-infective activity for the study of papillomavirus infections.</p>Fórmula:C13H15N5Pureza:99.08% - 99.53%Cor e Forma:SolidPeso molecular:241.29DDG-39
CAS:DDG-39 (1-(2,3-dideoxy-2-fluoropentofuranosyl)cytosine) possesses antiviral activity with potent and selective anti-HIV-1 and HBV activity in cell culture.Fórmula:C9H12FN3O3Pureza:99.17% - >99.99%Cor e Forma:SolidPeso molecular:229.21Selnoflast
CAS:<p>Selnoflast (RO-7486967) is an orally active, potent and selective NLRP3 inhibitor for the study of coronary arteries and ulcerative colitis.</p>Fórmula:C20H29N3O3SPureza:98.54% - 99.66%Cor e Forma:SolidPeso molecular:391.53
