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Imunologia e Inflamação

Imunologia e Inflamação

Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.

Subcategorias de "Imunologia e Inflamação"

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Foram encontrados 3055 produtos de "Imunologia e Inflamação"

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  • CDA-IN-3
    Targetmol
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    CDA-IN-3

    CAS:
    <p>CDA-IN-3 (NCDI) is a chitin deacetylase (CDA) inhibitor with antiparasitic properties. It disrupts chitin metabolism in nematodes, increasing ROS levels within these organisms and causing cellular damage. CDA-IN-3 significantly inhibits all developmental stages of Caenorhabditis elegans and can be utilized in research focused on anti-infective applications.</p>
    Fórmula:C16H27N3O3S2
    Cor e Forma:Solid
    Peso molecular:373.534

    Ref: TM-T206395

  • Nrf2-ARE/hMAO-B/QR2 modulator 1
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    Nrf2-ARE/hMAO-B/QR2 modulator 1

    CAS:
    <p>Nrf2-ARE/hMAO-B/QR2 modulator 1 a resveratrol derivative activated the NRF2-ARE inhibit hMAO-B and QR2, promote hippocampal neurogenesis Alzheimer's disease .</p>
    Fórmula:C14H12N2O3
    Pureza:98.5%
    Cor e Forma:Solid
    Peso molecular:256.26

    Ref: TM-T60395

  • Logotipo do CymitQuimica
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    CD73-IN-2

    <p>CD73-IN-2 is a potent inhibitor of CD73 (IC50: 0.09 nM).</p>
    Fórmula:C17H25ClN5O7P
    Cor e Forma:Solid
    Peso molecular:477.84

    Ref: TM-T63128

  • Logotipo do CymitQuimica
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    IRAK4-IN-12

    IRAK4-IN-12 (compound 37) is a potent inhibitor of IRAK4 (IC50: 0.015 μM) with cellular pIRAK4 potency (IC50: 0.5 μM).
    Fórmula:C24H31FN8O
    Cor e Forma:Solid
    Peso molecular:466.55

    Ref: TM-T62989

  • AS2690168 hydrochloride
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    AS2690168 hydrochloride

    CAS:
    <p>AS2690168 hydrochloride is an orally active inhibitor of RANKL signaling that can suppress RANKL-induced osteoclastogenesis in RAW264 cells. AS2690168 is applicable in research related to pathological bone resorption.</p>
    Fórmula:C17H15Cl2F3N4O
    Cor e Forma:Solid
    Peso molecular:419.228

    Ref: TM-T204813

  • NOD1/2 antagonist-1
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    NOD1/2 antagonist-1

    CAS:
    <p>NOD1/2 antagonist-1 inhibits NOD1 (IC50 1.13 μM) and NOD2 (IC50 0.77 μM), enhances paclitaxel antitumor efficacy and is used to study innate immune signaling.</p>
    Fórmula:C32H28ClF5N4O4
    Pureza:99.69%
    Cor e Forma:Solid
    Peso molecular:663.03

    Ref: TM-T72473

  • nNOS-IN-5
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    nNOS-IN-5

    CAS:
    <p>nNOS-IN-5 (Compound 9) is a potent inhibitor of human neuronal nitric oxide synthase (nNOS) with a Ki of 22 nM. It exhibits remarkable selectivity, being 900 times more selective for human nNOS over endothelial nitric oxide synthase (eNOS). nNOS-IN-5 is applicable in research related to neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.</p>
    Fórmula:C23H22N4O
    Cor e Forma:Solid
    Peso molecular:370.447

    Ref: TM-T206806

  • CD73-IN-18
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    CD73-IN-18

    CAS:
    <p>CD73-IN-18 (compound 35j) is an orally effective inhibitor of the extracellular 5'-nucleotidase (CD73) enzyme. It can be utilized in anticancer research.</p>
    Fórmula:C20H17N5O3
    Cor e Forma:Solid
    Peso molecular:375.38

    Ref: TM-T200672

  • TLR4/NF-κB/MAPK-IN-1
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    TLR4/NF-κB/MAPK-IN-1

    CAS:
    <p>TLR4/NF-κB/MAPK-IN-1 is a novel antineuroinflammatory agent that functions by inhibiting the TLR4/NF-κB/MAPK pathways.</p>
    Fórmula:C19H25BrO6
    Cor e Forma:Solid
    Peso molecular:429.3

    Ref: TM-T62359

  • ND-2158
    Targetmol
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    ND-2158

    CAS:
    <p>ND-2158 is a potent and selective inhibitor of IRAK4.</p>
    Fórmula:C22H30N4O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:446.56

    Ref: TM-T28144

  • AhR agonist 2
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    AhR agonist 2

    <p>AhR agonist 2 is aryl hydrocarbon receptor (AhR) agonist,oral, inducing rapid nuclear enrichment of the AhR and facilitating skin barrier repair,psoriasis.</p>
    Fórmula:C12H7Br2N3
    Cor e Forma:Solid
    Peso molecular:353.01

    Ref: TM-T61244

  • NLRP3-IN-70
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    NLRP3-IN-70

    CAS:
    <p>NLRP3-IN-70 (Compound 5m) is an inhibitor of the NLRP3 inflammasome with low oral bioavailability. It binds directly to the NACHT domain of the NLRP3 protein, thereby blocking its interaction with ASC, which inhibits ASC oligomerization and the assembly of the NLRP3 inflammasome. NLRP3-IN-70 is applicable in studies on sepsis and non-alcoholic steatohepatitis.</p>
    Fórmula:C23H23NO5
    Cor e Forma:Solid
    Peso molecular:393.432

    Ref: TM-T205527

  • DBMB
    Targetmol
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    DBMB

    CAS:
    <p>DBMB is a spleen tyrosine kinase (Syk) inhibitor that significantly suppresses Syk enzyme activity. It possesses anti-inflammatory properties by inhibiting NF-κB signaling, thereby reducing the production of inflammatory mediators such as nitric oxide (NO) and prostaglandin E2 (PGE2). DBMB can be utilized in research on inflammatory diseases.</p>
    Fórmula:C24H22N4O
    Cor e Forma:Solid
    Peso molecular:382.458

    Ref: TM-T204568

  • Logotipo do CymitQuimica
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    IRAK4-IN-19

    <p>IRAK4-IN-19, an IRAK4 inhibitor (IC50: 4.3 nM), hampers IL23 synthesis and arthritis progression.</p>
    Fórmula:C25H26F2N8O
    Cor e Forma:Solid
    Peso molecular:492.52

    Ref: TM-T63315

  • Cbl-b-IN-1
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    Cbl-b-IN-1

    CAS:
    Cbl-b-IN-1 is a potent Cbl-b inhibitor (IC50 <100 nM) with potential anticancer activity for the study of intestinal inflammation.
    Fórmula:C29H34N6O2
    Pureza:99.68%
    Cor e Forma:Solid
    Peso molecular:498.631

    Ref: TM-T37356

  • Logotipo do CymitQuimica
    Targetmol
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    IRAK4-IN-18

    <p>IRAK4-IN-18: Potent IRAK4 inhibitor (IC50: 15 nM), reduces IL23 in cells, prevents rat arthritis.</p>
    Fórmula:C24H25FN6O3
    Cor e Forma:Solid
    Peso molecular:464.49

    Ref: TM-T62950

  • MALT1-IN-11
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    MALT1-IN-11

    CAS:
    <p>MALT1-IN-11: MALT1 inhibitor, IC50 &lt;10-100 nM, reduces IL10, for cancer/autoimmune research.</p>
    Fórmula:C20H16F4N8O
    Cor e Forma:Solid
    Peso molecular:460.39

    Ref: TM-T73019

  • YM-I-26
    Targetmol
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    YM-I-26

    CAS:
    <p>YM-I-26 is a selective inhibitor of the NLRP3 inflammasome. This compound enhances the phagocytic activity of β-amyloid in murine microglial BV2 cells and reduces the production of IL-1β and IL-10. YM-I-26 is useful for research into inflammation-related immunomodulatory activities.</p>
    Fórmula:C28H33ClN2O5S2
    Cor e Forma:Solid
    Peso molecular:577.16

    Ref: TM-T200649

  • Itaconic acid prodrug-1
    Targetmol
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    Itaconic acid prodrug-1

    CAS:
    <p>Itaconic acid prodrug-1 (Compound P2) is an orally active prodrug of Itaconic acid that efficiently delivers Itaconic acid to skin tissues upon oral administration. It exhibits immunomodulatory effects, significantly inhibiting Poly(I:C)/IFNγ-induced inflammatory cytokines in human epidermal keratinocytes. Itaconic acid prodrug-1 is useful for research into alopecia areata and other inflammatory skin conditions.</p>
    Fórmula:C15H22O10
    Cor e Forma:Solid
    Peso molecular:362.329

    Ref: TM-T204591

  • NOD1-IN-1
    Targetmol
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    NOD1-IN-1

    CAS:
    <p>NOD1/2-IN-1 (Compound 2) is a potent inhibitor of RIPK2 with an IC50 value of 0.65 nM as determined by the ADP-Glo assay. It selectively inhibits the NOD1 pathway, with an IC50 of 33 nM, effectively blocking the production of pro-inflammatory cytokines and thereby reducing inflammatory responses. This compound has potential applications in the research of colitis.</p>
    Fórmula:C16H14ClN3O3
    Cor e Forma:Solid
    Peso molecular:331.75

    Ref: TM-T200671