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Imunologia e Inflamação

Imunologia e Inflamação

Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.

Subcategorias de "Imunologia e Inflamação"

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Foram encontrados 3055 produtos de "Imunologia e Inflamação"

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  • Logotipo do CymitQuimica
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    UM-3006

    CAS:
    UM-3006 is a potent TLR7/8 agonist that enhances immune responses by activating the TLR signaling pathway. This compound holds significant research and application potential in the fields of vaccine adjuvants and immune diseases.
    Fórmula:C20H34N6O2
    Peso molecular:390.52

    Ref: TM-T201866

  • SP11
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    SP11

    CAS:
    <p>SP11 is a mitochondrial reactive oxygen species (ROS) inhibitor. It activates Fis1 with an IC50 of 9.4 µM by binding to Cys41 and enhances the translocation of Drp1 to mitochondria. SP11 is utilized for research into oxidative stress damage.</p>
    Fórmula:C18H19ClN2OS
    Cor e Forma:Solid
    Peso molecular:346.87

    Ref: TM-T207379

  • MALT1-IN-5
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    MALT1-IN-5

    CAS:
    <p>MALT1-IN-5 is a potent inhibitor of the MALT1 protease and can be used in cancer research.</p>
    Fórmula:C17H17ClF2N6O3
    Cor e Forma:Solid
    Peso molecular:426.80

    Ref: TM-T62323

  • α-Gracinoic acid
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    α-Gracinoic acid

    CAS:
    <p>α-Gracinoic acid acts as an inhibitor of mPGES-1, exhibiting anti-inflammatory properties.</p>
    Fórmula:C29H42O4
    Cor e Forma:Solid
    Peso molecular:454.64

    Ref: TM-T200464

  • Logotipo do CymitQuimica
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    COX-2-IN-8

    <p>COX-2-IN-8 (Compound 6a) is a potent, selective, orally active COX-2 inhibitor (IC50: 6.585 μM) with a higher COX-2 selectivity than Celecoxib.</p>
    Fórmula:C19H19N3O4S2
    Cor e Forma:Solid
    Peso molecular:417.5

    Ref: TM-T62175

  • Logotipo do CymitQuimica
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    LD03-DEX

    CAS:
    LD03-DEX is a precursor compound of dexamethasone, characterized by its immunosuppressive activity.
    Fórmula:C44H65FO8
    Peso molecular:740.98

    Ref: TM-T201519

  • Logotipo do CymitQuimica
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    AMS-17

    <p>AMS-17, a strong NLRP3 inhibitor, quells microglia activation and cytokines like caspase-1, TNF-α, IL-1β, iNOS in studies.</p>
    Fórmula:C15H13F3N4O3S
    Cor e Forma:Solid
    Peso molecular:386.35

    Ref: TM-T61709

  • 2-Guanidinobezimidazole
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    2-Guanidinobezimidazole

    CAS:
    <p>2-Guanidinobenzimidazole (2GBI) is a selective agonist of NLRP3, with a KD value of 1.29 μM for His-GFP-NLRP3. It directly binds to the LRR domain of NLRP3, facilitating the assembly and activation of the inflammasome. Additionally, 2-Guanidinobenzimidazole enhances antitumor immunity, inhibits tumor growth, and overcomes resistance to immune checkpoint blockade (ICB).</p>
    Fórmula:C8H9N5
    Cor e Forma:Solid
    Peso molecular:175.191

    Ref: TM-T206771

  • MAY0132
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    MAY0132

    CAS:
    <p>MAY0132 is a potent and selective EPAC2 inhibitor with an IC50 of 0.4 μM. It significantly inhibits the replication of HMPV, AdV, and RSV, reduces cytokine/chemokine production induced by viral infections, and suppresses NF-κB activation. MAY0132 exhibits antiviral activity and can be used in respiratory virus infection research.</p>
    Fórmula:C16H15ClF3N
    Cor e Forma:Solid
    Peso molecular:313.745

    Ref: TM-T204630

  • Corannulene
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    Corannulene

    CAS:
    <p>Corannulene is an agonist of the aromatic hydrocarbon receptor (AhR). It induces a lower cytotoxic response in liver cancer cells compared to Benzo[a]pyrene and shows potential for use in cancer research.</p>
    Fórmula:C20H10
    Cor e Forma:Solid
    Peso molecular:250.293

    Ref: TM-T204413

  • ODN 2088
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    ODN 2088

    CAS:
    <p>ODN 2088 is a potent inhibitor of TLR3, TLR7 and TLR9 that is non-cytotoxic and shows inhibition of the release of IFN-α and IL-6.</p>
    Cor e Forma:Solid

    Ref: TM-T64278

  • Amilo-5MER
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    Amilo-5MER

    CAS:
    <p>Amilo-5MER (5-MP) is an orally active and selective inhibitor of serum amyloid A (SAA). It specifically suppresses the release of pro-inflammatory cytokines IL-6 and IL-1β in SAA-activated cells. Amilo-5MER reduces chronic inflammation and alleviates symptoms of diseases such as rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and multiple sclerosis (MS). It holds potential for research in autoimmune and chronic inflammatory diseases.</p>
    Fórmula:C23H40N6O9S
    Cor e Forma:Solid
    Peso molecular:576.664

    Ref: TM-TP3229

  • Anti-inflammatory agent 102
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    Anti-inflammatory agent 102

    CAS:
    <p>Anti-inflammatory agent 102 (Compound 11a) is an orally effective anti-inflammatory compound. It exerts its effects by inhibiting the activation of the ASK1/p38 MAPKs/NF-κB signaling pathway. This agent displays significant anti-inflammatory activity by suppressing the release of NO, ROS, and inflammatory cytokines such as IL-6, TNF-α, and IL-1β. Anti-inflammatory agent 102 is applicable in research concerning inflammatory diseases, including ulcerative colitis (UC).</p>
    Fórmula:C16H16ClN3O3
    Cor e Forma:Solid
    Peso molecular:333.77

    Ref: TM-T207168

  • mPGES1-IN-5
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    mPGES1-IN-5

    CAS:
    mPGES1-IN-5 (compound 18) is a multi-substituted pyrimidine compound that acts as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and demonstrates significant inhibitory activity in vivo against acute inflammation models.
    Fórmula:C27H27N3O
    Cor e Forma:Solid
    Peso molecular:409.52

    Ref: TM-T200592

  • WK692
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    WK692

    CAS:
    <p>Compound WK692 (compund WK692) is a BCL6 inhibitor that effectively suppresses the growth of diffuse large B-cell lymphoma cells without toxic side effects and acts synergistically with inhibitors of EZH2 and PRMT5.</p>
    Fórmula:C26H28Br2N8O5
    Cor e Forma:Solid
    Peso molecular:692.36

    Ref: TM-T201068

  • Logotipo do CymitQuimica
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    Heme Oxygenase-1-IN-2

    <p>Heme Oxygenase-1-IN-2 is a novel inhibitor of heme oxygenase-1 (HO-1), displaying potent antiproliferative activity in vitro, with an IC50 value of 0.95 μM.</p>
    Fórmula:C19H18ClN3O
    Cor e Forma:Solid
    Peso molecular:339.82

    Ref: TM-T61078

  • ASP-8731
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    ASP-8731

    CAS:
    <p>ASP8731 is a selective inhibitor of BACH1 that prevents inflammation and vascular occlusion, and induces fetal hemoglobin in sickle cell disease.</p>
    Fórmula:C20H21N5O4
    Cor e Forma:Solid
    Peso molecular:395.41

    Ref: TM-T201687

  • CVN293
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    CVN293

    CAS:
    <p>CVN293 is a inhibitor of the potassium channel KCNK13,BBB,It inhibits the production of the pro-inflammatory cytokine IL-1β induced by NLRP3 in microglia</p>
    Fórmula:C14H10FN7O
    Pureza:99.50%
    Cor e Forma:Solid
    Peso molecular:311.27

    Ref: TM-T86109

  • ROS inducer 9
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    ROS inducer 9

    CAS:
    <p>ROS inducer 9 (compound 4e) is an antibacterial agent with a minimum inhibitory concentration (MIC) of 0.25 μg/mL against Escherichia coli. It eradicates bacteria by inhibiting GSH activity and increasing ROS levels. Additionally, ROS inducer 9 exhibits low toxicity toward red blood cells and RAW 264.7 cells.</p>
    Fórmula:C26H26BrF4N3O3
    Cor e Forma:Solid
    Peso molecular:584.401

    Ref: TM-T206928

  • FAPI-74
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    FAPI-74

    CAS:
    <p>FAPI-74 is a PET (positron emission tomography) tracer involved in early FAPI-PET imaging.FAPI-74 can be used to study cancer tumors and degenerative diseases.</p>
    Fórmula:C36H49N9O8
    Cor e Forma:Solid
    Peso molecular:735.83

    Ref: TM-T78667