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Imunologia e Inflamação

Imunologia e Inflamação

Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.

Subcategorias de "Imunologia e Inflamação"

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Foram encontrados 3054 produtos de "Imunologia e Inflamação"

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  • Rafutrombopag
    Targetmol
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    Rafutrombopag

    CAS:
    <p>Rafutrombopag is a thrombopoietin (TPO) agonist.</p>
    Fórmula:C25H22N4O5
    Cor e Forma:Solid
    Peso molecular:458.47

    Ref: TM-T62865

  • BMY-25551
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    BMY-25551

    CAS:
    BMY-25551, a Mitomycin A analog, exhibits cytotoxicity 8 to 20 times greater than Mitomycin C against both murine and human tumor cell lines. It is applicable in research pertaining to cancer and hematological disorders.
    Fórmula:C17H21N3O7
    Cor e Forma:Solid
    Peso molecular:379.36

    Ref: TM-T201024

  • CD73-IN-18
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    CD73-IN-18

    CAS:
    <p>CD73-IN-18 (compound 35j) is an orally effective inhibitor of the extracellular 5'-nucleotidase (CD73) enzyme. It can be utilized in anticancer research.</p>
    Fórmula:C20H17N5O3
    Cor e Forma:Solid
    Peso molecular:375.38

    Ref: TM-T200672

  • Logotipo do CymitQuimica
    Targetmol
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    NF-κB-IN-6

    <p>NF-κB-IN-6 (Compound 3d) is an anti-inflammatory agent that works by reducing the protein expression of iNOS and COX-2 by suppressing the NF-κB signaling</p>
    Fórmula:C14H20N2O3
    Cor e Forma:Solid
    Peso molecular:264.32

    Ref: TM-T60433

  • Logotipo do CymitQuimica
    Targetmol
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    IRAK4-IN-19

    <p>IRAK4-IN-19, an IRAK4 inhibitor (IC50: 4.3 nM), hampers IL23 synthesis and arthritis progression.</p>
    Fórmula:C25H26F2N8O
    Cor e Forma:Solid
    Peso molecular:492.52

    Ref: TM-T63315

  • 6-Alkyne-F-araNAD
    Targetmol
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    6-Alkyne-F-araNAD

    CAS:
    <p>6-Alkyne-F-araNAD is an irreversible CD38 inhibitor that aids in better visualization of intracellular CD38 localization when used alongside other fluorescent probes (such as SR101−F-araNMN).</p>
    Fórmula:C24H28FN7O13P2
    Cor e Forma:Solid
    Peso molecular:703.464

    Ref: TM-T206560

  • MALT1-IN-11
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    MALT1-IN-11

    CAS:
    <p>MALT1-IN-11: MALT1 inhibitor, IC50 &lt;10-100 nM, reduces IL10, for cancer/autoimmune research.</p>
    Fórmula:C20H16F4N8O
    Cor e Forma:Solid
    Peso molecular:460.39

    Ref: TM-T73019

  • NLRP3-IN-8
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    NLRP3-IN-8

    CAS:
    <p>NLRP3-IN-8, orally active inflammasome blocker, IC50 of 1.23μM, stable (t1/2 = 138.63min), non-toxic (IC50 &gt;100μM).</p>
    Fórmula:C23H20N2O6
    Cor e Forma:Solid
    Peso molecular:420.41

    Ref: TM-T62221

  • YM-I-26
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    YM-I-26

    CAS:
    <p>YM-I-26 is a selective inhibitor of the NLRP3 inflammasome. This compound enhances the phagocytic activity of β-amyloid in murine microglial BV2 cells and reduces the production of IL-1β and IL-10. YM-I-26 is useful for research into inflammation-related immunomodulatory activities.</p>
    Fórmula:C28H33ClN2O5S2
    Cor e Forma:Solid
    Peso molecular:577.16

    Ref: TM-T200649

  • NOD1-IN-1
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    NOD1-IN-1

    CAS:
    <p>NOD1/2-IN-1 (Compound 2) is a potent inhibitor of RIPK2 with an IC50 value of 0.65 nM as determined by the ADP-Glo assay. It selectively inhibits the NOD1 pathway, with an IC50 of 33 nM, effectively blocking the production of pro-inflammatory cytokines and thereby reducing inflammatory responses. This compound has potential applications in the research of colitis.</p>
    Fórmula:C16H14ClN3O3
    Cor e Forma:Solid
    Peso molecular:331.75

    Ref: TM-T200671

  • (R)-Ketoprofen
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    (R)-Ketoprofen

    CAS:
    <p>(R)-Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that exhibits oral activity and analgesic properties. Unlike its counterpart, (R)-Ketoprofen does not significantly enhance the increase of inflammatory cytokines (such as Tumor Necrosis Factor (TNF) and Interleukin-1 (IL-1)) induced by LPS. However, it can inhibit the anti-inflammatory activity of (S)-Ketoprofen.</p>
    Fórmula:C16H14O3
    Cor e Forma:Solid
    Peso molecular:254.28

    Ref: TM-T200162

  • GNE-2256
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    GNE-2256

    CAS:
    <p>GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has</p>
    Fórmula:C24H27FN6O4
    Cor e Forma:Solid
    Peso molecular:482.51

    Ref: TM-T73372

  • α-Gracinoic acid
    Targetmol
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    α-Gracinoic acid

    CAS:
    <p>α-Gracinoic acid acts as an inhibitor of mPGES-1, exhibiting anti-inflammatory properties.</p>
    Fórmula:C29H42O4
    Cor e Forma:Solid
    Peso molecular:454.64

    Ref: TM-T200464

  • Logotipo do CymitQuimica
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    TIM-3-IN-1

    <p>TIM-3-IN-1 is a useful tool to enable further studies on the biology of TIM-3 immunoregulation in cancer.</p>
    Fórmula:C20H16ClN7O3S
    Cor e Forma:Solid
    Peso molecular:469.9

    Ref: TM-T63029

  • VS-15
    Targetmol
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    VS-15

    CAS:
    <p>VS-15 is a selective inhibitor of IDO1, specifically binding to its apo-heme form. Additionally, VS-15 serves as an inhibitor of iNOS.</p>
    Fórmula:C29H27N5O3
    Cor e Forma:Solid
    Peso molecular:493.56

    Ref: TM-T200480

  • NLRP3-IN-53
    Targetmol
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    NLRP3-IN-53

    CAS:
    <p>NLRP3-IN-53 (compound 1) is an NLRP3 inhibitor with an IC50 of 3.4nM.</p>
    Fórmula:C22H27N5O4
    Cor e Forma:Solid
    Peso molecular:425.48

    Ref: TM-T200482

  • mPGES1-IN-4
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    mPGES1-IN-4

    CAS:
    <p>mPGES1-IN-4 (compound 32) is a multi-substituted pyrimidine compound acting as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and significantly suppresses acute inflammation models in vivo.</p>
    Fórmula:C27H25F2N3O
    Cor e Forma:Solid
    Peso molecular:445.50

    Ref: TM-T200542

  • S-MTC acetate
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    S-MTC acetate

    CAS:
    S-MTC acetate (S-Methyl-L-thiocitrulline acetate) serves as a potent inhibitor of inducible nitric oxide synthases and is especially effective in inhibiting the constitutive (neuronal) type rather than the inducible (endothelial) type.
    Fórmula:C9H19N3O4S
    Cor e Forma:Solid
    Peso molecular:265.33

    Ref: TM-T201332

  • IL-17 modulator 1 disodium
    Targetmol
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    IL-17 modulator 1 disodium

    CAS:
    <p>Potent, orally active IL-17 Modulator 1 (disodium) from patent WO 2020127685, used in psoriasis and arthritis research.</p>
    Fórmula:C28H37N6NaO6P
    Cor e Forma:Solid
    Peso molecular:607.604

    Ref: TM-T36525

  • Logotipo do CymitQuimica
    Targetmol
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    COX-2-IN-29

    <p>COX-2-IN-29 is a selective inhibitor of orally active COX-2 (IC50: 0.005 μM).</p>
    Fórmula:C22H23FN2O6S2
    Cor e Forma:Solid
    Peso molecular:494.56

    Ref: TM-T63336