Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(148 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(60 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(444 produtos)
- NOD(17 produtos)
- NOS(63 produtos)
- Nrf2(79 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3045 produtos de "Imunologia e Inflamação"
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PROTAC IRAK4 degrader-4
CAS:<p>PROTAC IRAK4 degrader-4 is a targeted Cereblon-based molecule for degrading IRAK4.</p>Fórmula:C41H38F3N11O10Cor e Forma:SolidPeso molecular:901.817PF-06426779
CAS:<p>PF-06426779 is a potent and selective inhibitor of interleukin 1 receptor associated kinase 4 (IRAK4) , with an IC 50 of 0.3 nM.</p>Fórmula:C17H18FN3O4Cor e Forma:SolidPeso molecular:347.346NLRP3-IN-12
<p>NLRP3-IN-12 inhibits NLRP3 inflammasome, curbing IL-1β release with 0.45 μM IC50, for inflammatory bowel disease research.</p>Fórmula:C27H32ClNO7Cor e Forma:SolidPeso molecular:518PSMA-IN-3
<p>PSMA-IN-3 (compound 17) is a novel, high-affinity inhibitor of Prostate-Specific Membrane Antigen (PSMA) with an inhibitory concentration (IC50) of 13 nM,</p>Fórmula:C43H50FN7O15Cor e Forma:SolidPeso molecular:923.89HPPD-IN-1
<p>HPPD-IN-1 (compound II-3), a potent HPPD inhibitor, exhibits inhibitory activity against Arabidopsis thaliana HPPD (AtHPPD) with an IC50 of 0.248 μM, surpassing</p>Fórmula:C12H6F3NO4Cor e Forma:SolidPeso molecular:285.18Anticonvulsant agent 10
<p>Anticonvulsant agent 10 (Compound 6d) is an inhibitor targeting the Keap1-Nrf2 interaction, with a strong activity showing an ED50 of 0.04 mmol/kg. By inhibiting the Keap1-Nrf2 binding, it activates the Nrf2/ARE pathway, providing anticonvulsant and neuroprotective effects, making it useful for research in epilepsy and neuroprotection.</p>Cor e Forma:Odour SolidSTING agonist-13
CAS:<p>STING agonist-13 boosts cancer immunity by activating STING pathway, reducing tumors, and enhancing immune memory.</p>Fórmula:C45H53N15O7Cor e Forma:SolidPeso molecular:916FGT-4
<p>FGT-4 is a chimeric molecule targeting folate receptor β (FR-β) and functions as a TLR7 agonist. It enhances the secretion of iNOS and the pro-inflammatory cytokine IL-6 associated with M1 macrophages and promotes the proliferation of cytotoxic CD8+ T cells. FGT-4 demonstrates antitumor activity in the 4T1 breast cancer mouse model and is applicable for cancer immunotherapy research.</p>Fórmula:C50H57N11O9S2Cor e Forma:SolidPeso molecular:1019.37821PSB-24000
<p>PSB-24000 (Compound 27) is a selective ecto-5'-nucleotidase (CD73) inhibitor with a Ki value of 563 nM for inhibiting human CD73, and a Ki of 481 nM in membrane-bound CD73 in triple-negative breast cancer cells. It disrupts CD73’s recognition and action on substrate AMP, preventing AMP-induced immunosuppressive and pro-cancer adenosine production. PSB-24000 is promising for cancer research.</p>Cor e Forma:Odour SolidAB-680 ammonium
<p>AB-680: potent, reversible CD73 inhibitor, Ki=4.9 pM, >10,000-fold selectivity vs CD39, anti-tumor.</p>Fórmula:C20H30ClFN6O9P2Cor e Forma:SolidPeso molecular:614.89Lintuzumab
CAS:<p>Lintuzumab (HuM-195) is an uncoupled humanized mouse monoclonal antibody against CD33 with anti-leukemic activity.</p>Pureza:98% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.2% (SEC-HPLC)Cor e Forma:LiquidEG01377 2HCl
CAS:<p>EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377</p>Fórmula:C26H32Cl2N6O6S2Pureza:98.91%Cor e Forma:SoildPeso molecular:659.6CD73-IN-17
<p>CD73-IN-17 (compound 19) is an inhibitor of CD73 with an IC50 of 0.1 μM against hCD73. It is applicable in cancer research.</p>Cor e Forma:Odour SolidTMV-IN-6
<p>TMV-IN-6 (Compound 4g) serves as a novel antiviral and fungicidal agent that impedes tobacco mosaic virus (TMV) assembly, functioning by attachment to TMV coat</p>Fórmula:C29H27N3OSCor e Forma:SolidPeso molecular:465.61TLR8 agonist 2 hydrochloride
CAS:<p>TLR8 agonist 2 hydrochloride: potent for human TLR8 (EC50 3 nM), weak for TLR7 (EC50 33.33 μM).</p>Fórmula:C16H22N8·xHClCor e Forma:SolidKTX-497
CAS:<p>KTX-497, an IRAK4 degrader, demonstrates a potent DC50 value of 3 nM. It is utilized in oncology research[1].</p>Fórmula:C45H49F3N8O6Cor e Forma:SolidPeso molecular:854.92Dihydrorhodamine 6G
CAS:<p>DHR 6G, nonfluorescent reduced Rhodamine 6G, permeates cells, indicating ROS by oxidizing to fluorescent form in mitochondria.</p>Fórmula:C28H32N2O3Cor e Forma:SolidPeso molecular:444.572-Aminoquinoline
CAS:<p>Compound Fr16621, with CAS No. 580-22-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16621 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C9H8N2Cor e Forma:Light Yellow CrystalsPeso molecular:144.18R-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Fórmula:C22H19N3O2S2Cor e Forma:SolidPeso molecular:421.54Polyinosinic acid
CAS:<p>Polyinosinic acid: single-strand, TLR3 agonist, boosts immune response, has immune regulation uses.</p>Fórmula:(C10H13N4O8P)xCor e Forma:Solid
