Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(140 produtos)
- CXCR(153 produtos)
- Parede celular(5 produtos)
- Receptor IL(108 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(24 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(445 produtos)
- NOD(17 produtos)
- NOS(62 produtos)
- Nrf2(82 produtos)
- PGE Sintase(31 produtos)
- ROS(70 produtos)
- TGF-beta/Smad(59 produtos)
- TLR(74 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3269 produtos de "Imunologia e Inflamação"
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Chemokine Inhibitor Library
<p>A unique collection of xnum chemokines or chemokine receptors targeted compounds for high throughput and high content screening;</p>Cor e Forma:Odour SolidHPPD-IN-1
<p>HPPD-IN-1 (compound II-3), a potent HPPD inhibitor, exhibits inhibitory activity against Arabidopsis thaliana HPPD (AtHPPD) with an IC50 of 0.248 μM, surpassing</p>Fórmula:C12H6F3NO4Cor e Forma:SolidPeso molecular:285.182,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside
CAS:<p>2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside is a chlorophenyl glycoside that is commonly found in the bulbs of</p>Fórmula:C20H27Cl3O12Cor e Forma:SolidPeso molecular:565.78Biotin-labeled ODN 2088 sodium
Biotin-labeled ODN 2088 (sodium) acts as a potent inhibitor of TLR3, TLR7, and TLR9.Cor e Forma:Odour SolidFLY26
FLY26 is a selective partial antagonist of GluN2B, with an IC50 value of 0.64 μM. FLY26 inhibits the GluN2B subunit of NMDA receptors, reducing calcium ion influx and reactive oxygen species (ROS) production. It also activates the BDNF/TrkB/CREB neuroprotective signaling pathway, mitigating excitotoxicity and mitochondrial dysfunction. FLY26 holds potential for treating neurological deficits caused by cerebral ischemia-reperfusion injury.Fórmula:C22H23N5O3Cor e Forma:SolidPeso molecular:405.18009Pyroptosis Compound Library
<p>xnum types of active small molecules associated with pyroptosis for high-throughput and high-content screening.</p>Cor e Forma:LiquidTranscription Factor-Targeted Compound Library
<p>Well-chosen xnum compounds with unique structures targeting transcription factor;</p>Cor e Forma:Odour SolidSARS-CoV-2-IN-107
<p>SARS-CoV-2-IN-107 (Compound A7) is an inhibitor of SARS-CoV-2 3CLpro, with an IC50 of 261.3 nM. It inhibits the replication of SARS-CoV-2, exhibiting an EC50 of 11.7 μM. Additionally, SARS-CoV-2-IN-107 demonstrates anti-inflammatory activity in LPS-stimulated RAW264.7 macrophages, with a NO inhibition rate of 68.6%.</p>Fórmula:C15H11FO4Cor e Forma:SolidPeso molecular:274.244Nonsteroidal Anti-Inflammatory Compound Library
<p>xnum non-steroidal anti-inflammatory compounds for high-throughput and high-content screening.</p>Cor e Forma:Odour SolidJH-FK-08
<p>JH-FK-08 is an inhibitor of the serine/threonine-specific phosphatase enzyme calcineurin (calcium-dependent phosphatase). It demonstrates antifungal activity, effectively inhibiting C. neoformans with a MIC80 of 0.8 µg/mL. Additionally, JH-FK-08 exhibits immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM, and shows anti-infective activity in mouse models.</p>Fórmula:C45H73N3O13Cor e Forma:SolidPeso molecular:864.073Biotin-labeled ODN 1018 sodium
Biotin-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, serves as a tool for assessing cellular uptake and localization of CpG ODNs throughCor e Forma:Odour SolidPost-Translational Modification Compound Library
<p>Contains xnum active small molecules for research related to post-translational modifications (PTMs);</p>Cor e Forma:Odour SolidBuChE-IN-20
<p>BuChE-IN-20 is a selective hBuChE inhibitor (IC50= 0.13 μM) with the ability to cross the blood-brain barrier (BBB). This compound, a derivative of L-Tryptophan, exhibits neuroprotective effects by inhibiting nitric oxide (NO) production and reducing reactive oxygen species (ROS) levels. It effectively suppresses the self-aggregation of amyloid-beta (Aβ) peptides and is applicable in Alzheimer's disease research.</p>Cor e Forma:Odour SolidhCYP1B1-IN-1
hCYP1B1-IN-1 (compound B18) is an inhibitor of hCYP1B1 with an IC50 value of 3.6 nM and also acts as an antagonist of the Aryl Hydrocarbon Receptor.Fórmula:C18H14ClF3O3Cor e Forma:SolidPeso molecular:370.75CD22 ligand-1
CAS:CD22 ligand-1 is a potent, selective hCD22 binder (K D 0.335 µM) with potential for B-cell disease research.Fórmula:C33H34N5NaO10Cor e Forma:SolidPeso molecular:683.64NOX4-IN-1
NOX4-IN-1 (Compound 14m) is an inhibitor of NADPH oxidase 4 (NOX4) that reduces the production of reactive oxygen species (ROS). It also inhibits the TGF-β1/Smad signaling pathway, leading to decreased expression of fibrosis-related proteins. Additionally, NOX4-IN-1 impedes the migration of NRK-49F cells.Fórmula:C26H16ClN3O3Cor e Forma:SolidPeso molecular:453.877NT-0249
CAS:NT-0249 is an inflammatory vesicle NLRP3 inhibitor with anti-inflammatory activity that reverses high-fat diet-induced obesity.Fórmula:C22H28N5NaO4SPureza:98.11%Cor e Forma:SoildPeso molecular:481.54L-156,602
CAS:L-156,602 has a wide range of applications in life science related research.Fórmula:C38H64N8O13Cor e Forma:SolidPeso molecular:840.9735(S),15(S)-DiHETE
CAS:<p>5(S),15(S)-DiHETE, made by 15-LO from 5(S)-HETE, boosts human PMNL degranulation via PAF, not fMLP/A23187/LTB4, and lures eosinophils at ED50 of 0.3μM.</p>Fórmula:C20H32O4Cor e Forma:SolidPeso molecular:336.472Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH
Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH, a linker with TLR4-IN-C34, reduces inflammation in mice.Fórmula:C78H125N7O36Cor e Forma:SolidPeso molecular:1736.85
