Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(140 produtos)
- CXCR(153 produtos)
- Parede celular(5 produtos)
- Receptor IL(109 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(25 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(446 produtos)
- NOD(17 produtos)
- NOS(62 produtos)
- Nrf2(82 produtos)
- PGE Sintase(31 produtos)
- ROS(70 produtos)
- TGF-beta/Smad(59 produtos)
- TLR(76 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3304 produtos de "Imunologia e Inflamação"
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Mifamurtide sodium
CAS:Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009.Fórmula:C59H108N6NaO19PPureza:98%Cor e Forma:SolidPeso molecular:1259.48Anti-inflammatory agent 64
<p>Anti-inflammatory agent 64 (compound 4b) exhibits antioxidant and anti-inflammatory activities, effectively inhibiting the secretion of IL-6 and TNF-α while</p>Pureza:98%Cor e Forma:Odour SolidSericin
<p>Sericin is a globular protein isolated from silkworm cocoons. It has cognitive enhancement and pain-relieving properties. Additionally, Sericin serves as a cryoprotectant, potentially replacing fetal bovine serum or dimethyl sulfoxide (DMSO). It helps reduce oxidative stress and reactive oxygen species (ROS). Sericin aids in wound repair by promoting collagen production and exhibits activities such as antioxidant, antidiabetic, antihyperlipidemic, anti-inflammatory, moisturizing, wound healing promotion, antibacterial, and antitumor effects.</p>Cor e Forma:Odour SolidDEPMPO-biotin
CAS:DEPMPO is a stable nitrone for trapping O, N, S, C radicals, used in vivo/vitro with ESR. DEPMPO-biotin tags proteins' S-nitroso groups for analysis.Fórmula:C24H42N5O8PSCor e Forma:SolidPeso molecular:591.66KYN-101
CAS:<p>KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.</p>Fórmula:C22H19FN6Pureza:98.35%Cor e Forma:SolidPeso molecular:386.43Methyl 3,4-Dihydroxyphenylacetate
CAS:Methyl 3,4-Dihydroxyphenylacetate is an effective enterovirus 71 (EV71) inhibitor, suppressing EV71 replication in rhabdomyosarcoma (RD) cells, antiviral.Fórmula:C9H10O4Pureza:97.03%Cor e Forma:SolidPeso molecular:182.17cGAMP disodium
CAS:<p>cGAMP disodium, a bacterial CDN, boosts interferon production and activates STING, enhancing immune responses as a sublingual adjuvant.</p>Fórmula:C20H24N10O13P2·2NaCor e Forma:SoildPeso molecular:720.39Valeriandoid F
CAS:Valeriandoid F, an iridoid, strongly inhibits NO production (IC50: 0.88 μM) and has anti-inflammatory, antiproliferative effects.Fórmula:C23H34O9Cor e Forma:SolidPeso molecular:454.516JPE-1375
CAS:JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.Fórmula:C49H63FN10O9Cor e Forma:SolidPeso molecular:955.08Ketoprofen lysine salt
CAS:<p>Ketoprofen lysine salt is a lysine salt of ketoprofen, a Non-Steroidal Anti-Inflammatory Drug</p>Fórmula:C22H28N2O5Cor e Forma:SolidPeso molecular:400.48COX-2/15-LOX-IN-2
COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX.Fórmula:C27H26N6OS2Pureza:98%Cor e Forma:SolidPeso molecular:514.66Phytoene desaturase-IN-1
CAS:Potent PDS inhibitor with Kd of 65.9 μM, induces mRNA reduction and ROS accumulation, useful in agriculture.Fórmula:C18H13ClF3N3O2SCor e Forma:SolidPeso molecular:427.83Cyclic-di-GMP disodium
CAS:Cyclic-di-GMP disodium (5GP-5GP disodium) is a STING agonist and a second messenger in bacteria.Cost-effective and quality-assured.Fórmula:C20H22N10Na2O14P2Pureza:98.98% - 99.93%Cor e Forma:SolidPeso molecular:734.38TLR8 agonist 7
CAS:<p>TLR8 agonist7 is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of less than 250 nM. It remains stable in human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist7 demonstrates antitumor activity, achieving a tumor growth inhibition (TGI) rate of 98%.</p>Fórmula:C54H63N9O16Cor e Forma:SolidPeso molecular:1094.13PROTAC STING Degrader-1
CAS:PROTAC STING Degrader-1 (Compound SP23) is a STING-targeted PROTAC degrader exhibiting a DC50 of 3.2 μM and demonstrates anti-inflammatory activity [1].Fórmula:C34H33N7O10Cor e Forma:SolidPeso molecular:699.67STING agonist-8 dihydrochloride
STING Agonist-8 Dihydrochloride (Compound 5-AB) is a highly effective STING agonist, exhibiting an EC50 value of 27 nM in THP1-Dual KI-hSTING-R232 cells.Fórmula:C41H48Cl2N14O4Cor e Forma:SolidPeso molecular:871.82NF-κΒ activator 1
CAS:NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.Fórmula:C16H11FN2O2SPureza:99.58%Cor e Forma:SolidPeso molecular:314.33NOX4-IN-1
NOX4-IN-1 (Compound 14m) is an inhibitor of NADPH oxidase 4 (NOX4) that reduces the production of reactive oxygen species (ROS). It also inhibits the TGF-β1/Smad signaling pathway, leading to decreased expression of fibrosis-related proteins. Additionally, NOX4-IN-1 impedes the migration of NRK-49F cells.Fórmula:C26H16ClN3O3Cor e Forma:SolidPeso molecular:453.877JH-FK-08
<p>JH-FK-08 is an inhibitor of the serine/threonine-specific phosphatase enzyme calcineurin (calcium-dependent phosphatase). It demonstrates antifungal activity, effectively inhibiting C. neoformans with a MIC80 of 0.8 µg/mL. Additionally, JH-FK-08 exhibits immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM, and shows anti-infective activity in mouse models.</p>Fórmula:C45H73N3O13Cor e Forma:SolidPeso molecular:864.073Feeblin
CAS:<p>Feeblin (IRF5-IN-1) induces protein degradation, inhibits pro-inflammatory pathways, and is used for autoimmune disease research.</p>Fórmula:C27H33N3O2Pureza:99.58% - 99.88%Cor e Forma:SoildPeso molecular:431.57
