Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(62 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3055 produtos de "Imunologia e Inflamação"
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APF
CAS:<p>APF, a low-fluorescence probe, turns bright (490/515 nm) when oxidized by specific radicals; not affected by NO or H2O2.</p>Fórmula:C26H17NO5Cor e Forma:SolidPeso molecular:423.42TMV-IN-7
<p>TMV-IN-7 (compound G2) is a potent inhibitor of Tobacco Mosaic Virus (TMV). It exhibits strong hydrophobic interactions that prevent the virus from self-assembling.</p>Fórmula:C17H15ClN6OSPeso molecular:386.07166BMP-4
CAS:<p>BMP-4, a heparin-binding peptide, exhibits anti-inflammatory and anti-chondrogenic properties. In murine chondrocytes and macrophages, it effectively mitigates inflammation and alleviates symptoms of various arthritides by dose-dependently suppressing the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6 through modulation of the iNOS-IFN-IL6 signaling pathway.</p>Fórmula:C52H93N25O13SCor e Forma:SolidPeso molecular:1308.52PROTAC IRAK4 degrader-4
CAS:<p>PROTAC IRAK4 degrader-4 is a targeted Cereblon-based molecule for degrading IRAK4.</p>Fórmula:C41H38F3N11O10Cor e Forma:SolidPeso molecular:901.817NLRP3-IN-12
<p>NLRP3-IN-12 inhibits NLRP3 inflammasome, curbing IL-1β release with 0.45 μM IC50, for inflammatory bowel disease research.</p>Fórmula:C27H32ClNO7Cor e Forma:SolidPeso molecular:518BCL6 PROTAC 1
CAS:<p>BCL6 PROTAC 1: Selective BCL6 degrader, IC50 8.8 µM, used in DLBCL research.</p>Fórmula:C45H52ClN9O12Cor e Forma:SolidPeso molecular:946.4Pratensein
CAS:<p>Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.</p>Fórmula:C16H12O6Pureza:99.90%Cor e Forma:SolidPeso molecular:300.26Reltecimod TFA
<p>Reltecimod TFA (AB-103 TFA) is a CD28 antagonist and mimetic, inhibiting the stimulation of t-cells thereby attenuating acute inflammation NSTI.</p>Fórmula:C48H73F3N10O17SPureza:99.24% - 99.78%Cor e Forma:SolidPeso molecular:1151.21Pegtarazimod
CAS:Pegtarazimod (RLS-0071) inhibits the complement system through both the classical and lectin pathways. It suppresses myeloperoxidase (MPO) activity, leading to reduced ROS production, and decreases the formation of neutrophil extracellular traps (NET). Pegtarazimod exhibits anti-inflammatory properties and is applicable in the study of acute graft-versus-host disease.Fórmula:C122H224N20O46S2Cor e Forma:SolidPeso molecular:2771.32Reltecimod
CAS:Reltecimod, a CD28 antigen inhibitor, is used potentially for the treatment of necrotizing soft tissue infection.Fórmula:C46H72N10O15SPureza:98%Cor e Forma:SolidPeso molecular:1037.19AB-680 ammonium
<p>AB-680: potent, reversible CD73 inhibitor, Ki=4.9 pM, >10,000-fold selectivity vs CD39, anti-tumor.</p>Fórmula:C20H30ClFN6O9P2Cor e Forma:SolidPeso molecular:614.89PMX 205
CAS:<p>PMX 205 is an effective complement antagonist of the C5a receptor.</p>Fórmula:C45H62N10O6Pureza:98%Cor e Forma:SolidPeso molecular:839.04cGAMP diammonium
<p>cGAMP is a second messenger that triggers interferon production via STING activation upon detecting cytosolic DNA.</p>Fórmula:C20H30N12O13P2Cor e Forma:SolidPeso molecular:708.47TLR8 agonist 2 hydrochloride
CAS:<p>TLR8 agonist 2 hydrochloride: potent for human TLR8 (EC50 3 nM), weak for TLR7 (EC50 33.33 μM).</p>Fórmula:C16H22N8·xHClCor e Forma:Solid3-(3-Methoxyphenyl)acrylic acid
CAS:<p>3-(3-Methoxyphenyl)acrylic acid can inhibit free radical generation, has antioxidant potential, and can be used in biochemical experiments and drug synthesis.</p>Fórmula:C10H10O3Pureza:99.91%Cor e Forma:SolidPeso molecular:178.19Antibacterial agent 273
<p>Antibacterialagent 273 (Compound 15e) is an antimicrobial agent targeting bacterial cell membranes, effectively disrupting them with a MIC value of 4 μg/mL against Staphylococcus aureus. It causes the leakage of intracellular nucleic acids and proteins, inhibits bacterial metabolic activity, and induces the accumulation of reactive oxygen species (ROS) within bacteria. Antibacterialagent 273 is applicable in research on infections caused by Staphylococcus aureus.</p>Cor e Forma:Odour SolidAnticonvulsant agent 10
<p>Anticonvulsant agent 10 (Compound 6d) is an inhibitor targeting the Keap1-Nrf2 interaction, with a strong activity showing an ED50 of 0.04 mmol/kg. By inhibiting the Keap1-Nrf2 binding, it activates the Nrf2/ARE pathway, providing anticonvulsant and neuroprotective effects, making it useful for research in epilepsy and neuroprotection.</p>Cor e Forma:Odour SolidARC186
<p>ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.</p>Cor e Forma:SolidPeso molecular:120702.76FAPI-46
CAS:<p>FAPI-46 is a radiotracer for fibroblast activation protein (FAP),conjugated with 68Ga or 177Lu tracer for FAP tumours in positron emission tomography (PET).</p>Fórmula:C41H57F2N11O9Cor e Forma:SolidPeso molecular:885.96RDR03785
CAS:<p>The MIF Antagonist IV, RDR 03785 controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications.</p>Fórmula:C19H18F3NO4Pureza:98.92%Cor e Forma:SolidPeso molecular:381.35
