Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(148 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(60 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(444 produtos)
- NOD(17 produtos)
- NOS(63 produtos)
- Nrf2(79 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3045 produtos de "Imunologia e Inflamação"
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4-hydroperoxy 2-Nonenal
CAS:<p>4-HNE, a marker of oxidative stress, arises from oxidized ω-6 fats like linoleic acid and shows cytotoxic and genotoxic effects.</p>Fórmula:C9H16O3Cor e Forma:SolidPeso molecular:172.224Moxilubant HCl
CAS:<p>Moxilubant HCl: small molecule LTB4R antagonist for immune, skin, musculoskeletal disorders, and research in psoriasis, arthritis.</p>Fórmula:C26H38ClN3O4Pureza:99.94%Cor e Forma:SoildPeso molecular:492.05CIB-1476
<p>CIB-1476, a caspase-1 inhibitor, effectively reduces joint swelling in mouse models of arthritis and demonstrates lasting anti-inflammatory effects. This compound achieves its benefits by blocking IL-1β production, NF-κB activation, and GSDMD-mediated pyroptosis, all of which are triggered by the NLRP3 inflammasome.</p>Fórmula:C28H28N2O6SCor e Forma:SolidPeso molecular:520.6Antifungal agent 123
<p>Antifungalagent 123 (Compound 4b) demonstrates strong affinity for the oxidoreductase of Staphylococcus aureus or membrane proteins of Candida albicans, exhibiting both antibacterial and antifungal properties. Additionally, it is capable of scavenging free radicals, showcasing antioxidant effects. Antifungalagent 123 also inhibits the TLR signaling pathway and possesses anti-inflammatory activity.</p>Fórmula:C21H20N4O3Cor e Forma:SolidPeso molecular:376.409CD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Cor e Forma:SolidR-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Fórmula:C22H19N3O2S2Cor e Forma:SolidPeso molecular:421.54diABZI-V/C-DBCO
<p>Compound 3 (diABZI-V/C-DBCO) functions as an efficient STING agonist. This compound acts by releasing diABZI-amine under the action of cathepsin B to activate STING, thereby inducing the production of interferon and other immune-activating molecules, which enhances the immune system's response to tumors. In THP1-Dual cells, the EC50 values for STING activation by diABZI-V/C-DBCO and diABZI-amine are 1.47 nM and 0.144 nM, respectively, and in primary mouse splenic cells, the EC50 values are 7.7 µM and 0.17 µM, respectively. diABZI-V/C-DBCO is useful for research in the field of cancer immunotherapy.</p>Fórmula:C78H89N19O13Cor e Forma:SolidPeso molecular:1500.66TLR8 agonist 2
CAS:<p>TLR8 agonist 2 activates human TLR8 (EC50=3nM), less effective on TLR7 (EC50=33.33μM).</p>Fórmula:C16H22N8Cor e Forma:SolidPeso molecular:326.408Nrf2 activator-8
<p>Nrf2 Activator-8 (Compound 10e), with an EC50 of 37.9 nM, is a potent Nrf2 activator that demonstrates significant antioxidant and anti-inflammatory properties</p>Fórmula:C13H11ClN2O3SCor e Forma:SolidPeso molecular:310.763-O-(2'E,4'Z-Decadienoyl)ingenol
<p>3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.</p>Fórmula:C30H42O6Cor e Forma:SolidPeso molecular:498.66Keap1-Nrf2-IN-27
<p>Keap1-Nrf2-IN-27 is an inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI) with a KD2 value of 0.119 μM. It suppresses the expression of pro-inflammatory cytokines TNF-α and IL-6 in an LPS-induced RAW264.7 cell model.</p>Cor e Forma:Odour SolidMipeginterferon alfa-2b
CAS:<p>Mipeginterferon alfa-2b, an IFNA2b analogue, has 5 modified amino groups out of 11 and weighs 40 kDa.</p>Cor e Forma:LiquidUlevostinag
CAS:<p>Ulevostinag (MK-1454) is a STING agonist.</p>Fórmula:C20H22F2N10O9P2S2Cor e Forma:SolidPeso molecular:710.5224-Methylenecholesterol
CAS:<p>24-Methylenecholesterol (24 Methylenecholesterol) is a natural marine sterol, which stimulates cholesterol acyl transferase (ACAT) in human macrophages.</p>Fórmula:C28H46OPureza:98%Cor e Forma:SolidPeso molecular:398.66Tuparstobart
CAS:<p>Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on</p>Cor e Forma:LiquidInflexuside B
CAS:<p>Inflexuside B, an abietane diterpenoid derived from the aerial parts of Isodon inflexus, effectively inhibits lipopolysaccharide (LPS)-activated NO Synthase in</p>Fórmula:C35H48O11Cor e Forma:SolidPeso molecular:644.75TBK1/IKKε-IN-6
CAS:<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Fórmula:C31H36F2N8O4Cor e Forma:SolidPeso molecular:622.678RH-EDA
<p>RH-EDA, a rhodamine-based turn-on fluorescent probe, detects hydroxyl radicals ([OH]) in living systems.</p>Fórmula:C28H25N3O4Cor e Forma:SolidPeso molecular:467.52Ara-F-NAD+ sodium
<p>Ara-F-NAD+ sodium, an arabino analogue of NAD+, serves as a potent, reversible, and slow-binding inhibitor of the CD38 NADase [1] [2].</p>Fórmula:C21H25FN7NaO13P2Cor e Forma:SolidPeso molecular:687.4NLRP3-IN-45
<p>NLRP3-IN-45 (D6) serves as an inhibitor specifically targeting the NLRP3 inflammasome, demonstrated through its ability to curb the activity of IL-1β (IC 50 = 41.79 nM). It effectively prevents the activation of the NLRP3 inflammasome while sparing the initial stages of its activation process. Furthermore, NLRP3-IN-45 has been shown to selectively inhibit NLRP3 inflammasome activation in the LPS-induced acute lung injury (ALI) mouse model.</p>Fórmula:C27H30FNO6Cor e Forma:SolidPeso molecular:483.53
