Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(148 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(60 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(444 produtos)
- NOD(17 produtos)
- NOS(63 produtos)
- Nrf2(79 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3045 produtos de "Imunologia e Inflamação"
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CPG-52364
CAS:<p>CPG-52364 is a small molecule compound that interacts between an endosomal TLR and its ligand and is a candidate for the treatment of psoriasis.</p>Fórmula:C27H36N6O3Pureza:99.99%Cor e Forma:SolidPeso molecular:492.61BBIQ
CAS:<p>BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of 59.1</p>Fórmula:C21H22N4Pureza:99.71%Cor e Forma:SolidPeso molecular:330.43GSK2983559 free acid
CAS:<p>GSK2983559 free acid selectively inhibits RIP2, reducing inflammatory cytokines in human bowel disease.</p>Fórmula:C21H23N4O7PS2Pureza:97.8700% - 98.61%Cor e Forma:SolidPeso molecular:538.53YM-53403
CAS:<p>YM-53403: Antiviral that combats both RSV subgroup A/B, treats respiratory infections.</p>Fórmula:C36H29N3O3SPureza:98.49% - 98.85%Cor e Forma:SolidPeso molecular:583.7SC-75416
CAS:<p>SC-75416, a cyclooxygenase-2 (COX-2) inhibitor, is used potentially for the treatment of postoperative inflammation.</p>Fórmula:C15H14ClF3O3Pureza:98.67% - 98.67%Cor e Forma:SolidPeso molecular:334.72BRD56491
CAS:<p>BRD56491 is a small molecule ROS enhancer and a bioprobe for the detection of cancer.</p>Fórmula:C20H14O2Pureza:99.89%Cor e Forma:SolidPeso molecular:286.32Letosteine
CAS:<p>Letosteine, an oral expectorant, treats acute/chronic respiratory diseases by dissolving mucus and reducing inflammation.</p>Fórmula:C10H17NO4S2Pureza:96.03%Cor e Forma:SolidPeso molecular:279.38LDC7559
CAS:<p>LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.</p>Fórmula:C20H19N3O3Pureza:99.8%Cor e Forma:SoildPeso molecular:349.38FEN1-IN-3
CAS:<p>FEN1-IN-3 is a human flap endonuclease-1 ( hFEN1 ) inhibitor that stabilizes hFEN1 with an EC 50 of 6.8 μM .</p>Fórmula:C15H12N2O4Pureza:98.16%Cor e Forma:SolidPeso molecular:284.27CPS-11
CAS:<p>CPS-11, a Thalidomide analogue, shows potent, broad antitumor activity, especially in multiple myeloma cells.</p>Fórmula:C14H12N2O5Pureza:99.8% - 99.98%Cor e Forma:SolidPeso molecular:288.26Vipoglanstat
CAS:<p>Vipoglanstat: inhibits prostaglandin E synthase, anti-inflammatory, reduces leukocyte infiltration and lung injury from endotoxin/sepsis.</p>Fórmula:C30H34Cl2F5N5O3Cor e Forma:SolidPeso molecular:678.52Ginsenoside Rk1
CAS:<p>Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.</p>Fórmula:C42H70O12Pureza:98.46% - 99.13%Cor e Forma:SolidPeso molecular:767PDE4-IN-8
CAS:<p>PDE4-IN-8 is a potent PDE4 inhibitor with IC50 0.93 nM for PDE4B2 and minor impact on IL13, IL4, IFNy (IC50: 4.04, 36.33, 2394 nM).</p>Fórmula:C18H22BNO4Cor e Forma:SolidPeso molecular:327.18Oxidized ATP trisodium salt
CAS:<p>Oxidized ATP trisodium salt (oATP) is a broad-spectrum inhibitor of P2 receptors, irreversibly antagonizing P2X7R activation and inhibiting c-reactive protein (</p>Fórmula:C10H11N5Na3O13P3Pureza:98%Cor e Forma:SolidPeso molecular:571.11Cergutuzumab amunaleukin
CAS:<p>Cergutuzumab amunaleukin (CEA-IL2v) is a CEA-targeted IL-2 variant immunocytokine for combination cancer immunotherapy with anti-tumor activity.</p>Pureza:98% (SDS-PAGE); 99.7% (SEC-HPLC) - 98% (SDS-PAGE); 99.7% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:162.05 kDaFenquinotrione
CAS:<p>Fenquinotrione, a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor, exhibits IC50 values of 27.2 and 44.7 nM against HPPD from rice and Arabidopsis thaliana</p>Fórmula:C22H17ClN2O5Cor e Forma:SolidPeso molecular:424.83NLRP3-IN-21
CAS:<p>NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome that possesses anti-inflammatory properties.</p>Fórmula:C20H13Cl2F3N6O2SPureza:98%Cor e Forma:SolidPeso molecular:529.32NVS-MALT1
CAS:<p>NVS-MALT1 is an allosteric inhibitor of MALT1 [1].</p>Fórmula:C24H27ClF3N5O4SCor e Forma:SolidPeso molecular:574.02TLR4 agonist-1
CAS:<p>TLR4 agonist-1 (compound 17a) serves as a potent activator of Toll-like Receptor 4 (TLR4) and stimulates the production of MIP-1β in RAW 264.7 and MM6 cells [1</p>Fórmula:C81H158N3O15PCor e Forma:SolidPeso molecular:1445.11MALT1-IN-7
CAS:<p>MALT1-IN-7 (compound 142b) is a potent inhibitor of MALT1 protease with potential for cancer research.</p>Fórmula:C19H17F3N8O2SCor e Forma:SolidPeso molecular:478.45AMPCP
CAS:<p>AMPCP is an Ecto-5'-nucleotidase (CD73) inhibitor.</p>Fórmula:C11H15N5Na2O9P2Cor e Forma:SolidPeso molecular:469.19AHR antagonist 4
CAS:<p>AHR antagonist 4, potent with 82.2 nM IC50, inhibits AHR from patent WO2018146010A1 and shows anti-cancer properties.</p>Fórmula:C20H14F6N4O4Pureza:98%Cor e Forma:SolidPeso molecular:488.34AD 0261
CAS:<p>AD 0261 is a radical scavenger. It has a strong inhibitory action on the generation of lipid peroxides and superoxide anions.</p>Fórmula:C27H31F2N3OPureza:98%Cor e Forma:SolidPeso molecular:451.55IRAK inhibitor 3
CAS:<p>IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.</p>Fórmula:C21H21N5O4SPureza:98.86%Cor e Forma:SolidPeso molecular:439.49Thromboxane B3
CAS:<p>Thromboxane B3 (TXB3), the stable hydrolysis product of TXA3, is synthesized from eicosapentaenoic acid (EPA) through the action of COX and thromboxane synthase enzymes. This compound is biosynthesized in several tissues, including seminal vesicles, lungs, polymorphonuclear leukocytes (PMNL), and ocular tissues.</p>Fórmula:C20H32O6Cor e Forma:SolidPeso molecular:368.5Glutathione ethyl ester
CAS:<p>Glutathione ethyl ester is a cell-permeable, modified form of glutathione (GSH) that undergoes rapid hydrolysis by esterases in vivo to restore GSH levels.</p>Fórmula:C12H21N3O6SPureza:98.958%Cor e Forma:SoildPeso molecular:335.38Keap1-Nrf2-IN-15
CAS:<p>Keap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, displaying IC50 values of 77 nM in a fluorescence</p>Fórmula:C39H35N3O12S2Cor e Forma:SolidPeso molecular:801.84PF-184
<p>PF-184: potent IKK-2 inhibitor, selective over 30+ kinases; useful for asthma & COPD research. IC50: 37 nM.</p>Fórmula:C32H32ClFN6O4Cor e Forma:SolidPeso molecular:619.09ICy-Q
CAS:<p>ICy-Q, a NIR reagent activated by NQO-1, triggers pyroptosis in pancreatic cancer cells, aiding diagnosis.</p>Fórmula:C48H50I2N2O5Pureza:98%Cor e Forma:SolidPeso molecular:988.73CD73-IN-6
CAS:<p>CD73-IN-6, serves as a potent inhibitor of CD73. This compound finds utility in cancer research [1].</p>Fórmula:C20H15N7O2Cor e Forma:SolidPeso molecular:385.38GSK2256294A
CAS:<p>GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.</p>Fórmula:C21H24F3N7OPureza:99.86% - 99.86%Cor e Forma:SolidPeso molecular:447.46TLR8 agonist 6
CAS:<p>Compound A, a potent TLR8 agonist, exhibits an EC50 of 0.052 µM and promotes the production of IL-12p40 in human PBMCs with an EC50 of 0.031 µM.</p>Fórmula:C19H29N7O2Cor e Forma:SolidPeso molecular:387.48WEHI-345
CAS:<p>WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production.</p>Fórmula:C22H23N7OPureza:>99.99%Cor e Forma:SolidPeso molecular:401.46TLR7 agonist 4
CAS:<p>TLR7 agonist 4 (Compound 1.2) is a TLR7 agonist (EC50: 4.3 nM).</p>Fórmula:C23H34N6O3Cor e Forma:SolidPeso molecular:442.55RPR-106541
CAS:<p>RPR-106541, a GR agonist, is used potentially for the treatment of asthma.</p>Fórmula:C24H34F2O4SCor e Forma:SolidPeso molecular:456.59IRAK4-IN-6
CAS:<p>IRAK4-IN-6 is an oral IRAK4 inhibitor with a 4 nM IC50, targeting MyD88 L265P mutant DLBCL.</p>Fórmula:C25H32N10O2Pureza:98%Cor e Forma:SolidPeso molecular:504.59STING modulator-3
CAS:<p>STING modulator-3, a 43.1 nM R232 STING inhibitor, doesn't affect IRF-3 or TNF-β in THP-1 cells.</p>Fórmula:C18H17N9OCor e Forma:SolidPeso molecular:375.39MKA031
CAS:<p>MKA031 (compound 6y) is a non-competitive inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC50 of 1.7 μM.</p>Fórmula:C21H17N5O2SCor e Forma:SolidPeso molecular:403.46C5aR-IN-1
CAS:<p>C5aR-IN-1, a potent C5aR inhibitor, may aid in researching autoimmune and inflammatory diseases.</p>Fórmula:C36H39F4N3O2Cor e Forma:SolidPeso molecular:621.71PF 184
CAS:<p>IKKβ inhibitor</p>Fórmula:C32H32ClFN6O4Pureza:98%Cor e Forma:SolidPeso molecular:619.09TMV-IN-3
CAS:<p>TMV-IN-3 is a chalcone derivative that inhibits TMV with a 120.3 μg/mL EC50, used in research on infection and cancer.</p>Fórmula:C28H26O4Cor e Forma:SolidPeso molecular:426.5TLR8 agonist 5
CAS:<p>TLR8 Agonist 5, exhibiting potent efficacy as a TLR8 agonist, demonstrates an EC50 of 20 nM in HEK-Blue hTLR8, effectively activating the immune response.</p>Fórmula:C31H40N6O5Cor e Forma:SolidPeso molecular:576.69(S)-BI 665915
CAS:<p>(S)-BI 665915 is an orally active inhibitor of oxadiazole-containing 5-lipoxygenase-activating protein (FLAP)(IC50 of 1.7 nM for FLAP binding)..</p>Fórmula:C24H26N8O2Pureza:98%Cor e Forma:SolidPeso molecular:458.52CD73-IN-10
CAS:<p>CD73-IN-10, a potent inhibitor of CD73, aids in creating cancer drugs by hindering adenosine synthesis, which fosters tumor growth.</p>Fórmula:C15H13F2N5O2Cor e Forma:SolidPeso molecular:333.29TBK1-IN-1
CAS:<p>TBK1-IN-1 is a TANK-binding kinase 1 inhibitor with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.</p>Fórmula:C27H37N7O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:491.63MAPK-IN-1
CAS:<p>MAPK-IN-1 inhibits MAPK for Alzheimer's research with anti-inflammatory effects, IC50 of 23.84 μM against AChE.</p>Fórmula:C19H18O4Cor e Forma:SolidPeso molecular:310.34BW 755C
CAS:<p>BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.</p>Fórmula:C10H10F3N3Pureza:96.52%Cor e Forma:SolidPeso molecular:229.2STING agonist-11
CAS:<p>STING agonist-11 is a potent activator of the small molecule cyclic urea class of STING (EC50: 18 nM).STING activation is a highly promising immunotherapy.</p>Fórmula:C25H20ClF4N3O2Cor e Forma:SolidPeso molecular:505.89TMV-IN-5
CAS:<p>TMV-IN-5 (compound 1a) serves as an antiviral/antifungal agent, specifically targeting and inhibiting the assembly of the tobacco mosaic virus (TMV) by binding</p>Fórmula:C22H23N3SCor e Forma:SolidPeso molecular:361.5W-54011
CAS:<p>W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).</p>Fórmula:C30H37ClN2O2Pureza:96.8%Cor e Forma:SolidPeso molecular:493.08FEN1-IN-7
CAS:<p>FEN1-IN-7 (compound 16), a selective Flap endonuclease-1 (FEN1) inhibitor with an IC50 of 18 nM, plays a role in DNA damage repair in mammalian cells.</p>Fórmula:C16H14N2O6SPureza:98%Cor e Forma:SolidPeso molecular:362.36Argininosuccinic acid disodium
CAS:<p>Argininosuccinic acid disodium, involved in the urea cycle's fourth step, is cleaved by argininosuccinate lyase (ASL) into arginine and fumarate.</p>Fórmula:C10H16N4Na2O6Pureza:98%Cor e Forma:SolidPeso molecular:334.24EG01377
CAS:<p>EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.</p>Fórmula:C26H30N6O6S2Pureza:98%Cor e Forma:SolidPeso molecular:586.68NT-0796
CAS:<p>NT-0796 is an inflammasome NLRP3 inhibitor that inhibits NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.</p>Fórmula:C23H27N3O4Pureza:99.67%Cor e Forma:SolidPeso molecular:409.48Factor D inhibitor 6
CAS:<p>Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.</p>Fórmula:C23H22ClFN6O3Cor e Forma:SolidPeso molecular:484.92FEN1-IN-5
CAS:<p>FEN1-IN-5 (compound 12A) is a potent Flap endonuclease-1 (FEN1) inhibitor with an IC50 value of 12 nM, playing a role in DNA repair mechanisms [1].</p>Fórmula:C21H17N3O4SPureza:98%Cor e Forma:SolidPeso molecular:407.44CGA-JK3
CAS:<p>CGA-JK3 is an IkappaB kinase inhibitor in innate immune process.</p>Fórmula:C15H19NO3Pureza:98%Cor e Forma:SolidPeso molecular:261.32ST 2825
CAS:<p>ST 2825 is a specific MyD88 dimerization inhibitor. ST2825 inhibition of IL-1β-mediated activation of NF-κB transcriptional activity.</p>Fórmula:C27H28Cl2N4O5SPureza:98%Cor e Forma:SolidPeso molecular:591.51Keap1-Nrf2-IN-6
<p>Keap1-Nrf2-IN-6 is a potent, selective inhibitor of the Keap1-Nrf2 protein−protein interaction (PPI), demonstrating an inhibitory concentration (IC50) of 41 nM</p>Fórmula:C30H34N4O8SCor e Forma:SolidPeso molecular:610.68STING Agonist D61
CAS:<p>STING agonist D61 is a compound that activates the stimulator of interferon genes (STING), leading to the induction of IFN3-inducible secreted alkaline</p>Fórmula:C29H29F3N8O4Cor e Forma:SolidPeso molecular:610.60COX-2-IN-30
CAS:<p>COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =</p>Fórmula:C17H16N6O3SPureza:98%Cor e Forma:SolidPeso molecular:384.41BF738735
CAS:<p>BF738735 is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ, IC50 = 5.7 nM) showing higher activity over α(IC50 = 1.7 μM).</p>Fórmula:C21H19FN4O3SPureza:90%Cor e Forma:SolidPeso molecular:426.46BRP-201
CAS:<p>BRP-201: selective mPGES-1 inhibitor (IC50: 0.42 μM), potential next-gen anti-inflammatory drug.</p>Fórmula:C28H27ClN4OSCor e Forma:SolidPeso molecular:503.06Caspase-3 activator 1
<p>Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage.</p>Fórmula:C28H27N6O2RuS2Pureza:98%Cor e Forma:SolidPeso molecular:644.75(-)-Bornyl ferulate
CAS:<p>(-)-Bornyl ferulate is a dual inhibitor of 5-lipoxygenase and cyclooxygenase (COX), exhibiting half-maximal inhibitory concentrations (IC50s) of 10.4 μM for 5-</p>Fórmula:C20H26O4Pureza:98%Cor e Forma:SolidPeso molecular:330.42Nitric oxide production-IN-1
CAS:<p>Nitric oxide production-IN-1 (Compound 1) is an inhibitor of nitric oxide (NO) production extracted from Tupistra chinensis.</p>Fórmula:C33H52O15Pureza:98%Cor e Forma:SolidPeso molecular:688.76JT002
CAS:<p>JT002 is an orally active NLRP3 inflammasome inhibitor that decreases the production of NLRP3-dependent proinflammatory cytokines (such as IL-1β, IL-1α, IL-18)</p>Fórmula:C20H24N4O5SPureza:98%Cor e Forma:SolidPeso molecular:432.49TMV-IN-2
CAS:<p>TMV-IN-2, a chalcone, inhibits TMV with an EC50 of 89.9 μg/mL, used in infection and tumor studies.</p>Fórmula:C27H23FO4Cor e Forma:SolidPeso molecular:430.47OATD-02
CAS:<p>OATD-02 is an orally active, competitive, reversible, noncovalent inhibitor with slow offset kinetics that targets both Arginase1 and 2, exhibiting inhibitory</p>Fórmula:C12H25BN2O4Pureza:98%Cor e Forma:SolidPeso molecular:272.15NLRP3-IN-22
CAS:<p>NLRP3-IN-22 (Compound II-4) is an inhibitor of NLRP3, exhibiting a 67% inhibition rate at a concentration of 10 μM [1].</p>Fórmula:C19H12F3NO4SPureza:98%Cor e Forma:SolidPeso molecular:407.36Nrf2 activator-7
CAS:<p>Nrf2 Activator-7 (Compound 12b) effectively enhances the Nrf2 signaling pathway as a potent Nrf2 activator.</p>Fórmula:C35H32N2O11S2Cor e Forma:SolidPeso molecular:720.77Lobenzarit sodium
CAS:<p>Lobenzarit sodium (CCA) is an agent with the activity of antirheumatic and antioxidative.</p>Fórmula:C14H8ClNNa2O4Pureza:99.35%Cor e Forma:SolidPeso molecular:335.655J-4
CAS:<p>5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE).</p>Fórmula:C16H12N2O3SPureza:96.12%Cor e Forma:SolidPeso molecular:312.34Ro26-4550
CAS:<p>Ro26-4550 is a competitive reversible inhibitor of interleukin-2 (IL-2) binding to IL-2R α-subunit (IC50 = 3 μM).</p>Fórmula:C26H30N4O3Pureza:98%Cor e Forma:SolidPeso molecular:446.54TLR7/8 agonist 8
CAS:<p>TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of</p>Fórmula:C24H30N6OCor e Forma:SolidPeso molecular:418.53Friluglanstat
CAS:<p>Friluglanstat is an inhibitor of the enzyme prostaglandin E synthase (mPGES-1) and exhibits anti-inflammatory activity [1].</p>Fórmula:C25H20ClF3N4O3Pureza:98%Cor e Forma:SolidPeso molecular:516.9NLRP3-IN-18
CAS:<p>NLRP3-IN-18, also known as compound 13, is a potent inhibitor of NLRP3, demonstrating an IC50 value of ≤1.0 µM [1].</p>Fórmula:C19H18ClN3OPureza:98%Cor e Forma:SolidPeso molecular:339.82IKK-IN-4
CAS:<p>IKK-IN-4 is a potent and selective inhibitor of IkappaB kinase 2 with IC 50 values of 45 and 650 nM against IKKβ and IKKα, respectively [1].</p>Fórmula:C18H19N5SCor e Forma:SolidPeso molecular:337.44BI 7446
CAS:<p>BI 7446 is a potent and selective cyclic dinucleotide (CDN)-based stimulator of interferon genes (STING) agonist capable of activating all five STING variants</p>Fórmula:C20H22FN9O10P2S2Pureza:98%Cor e Forma:SolidPeso molecular:693.52TLR7/8 agonist 9
CAS:<p>TLR7/8 agonist 9 (Compound 25a), exhibiting EC50 values of 40 nM and 23 nM for hTLR7 and hTLR8 respectively, demonstrates anti-tumor properties and enhances the</p>Fórmula:C20H26N6OCor e Forma:SolidPeso molecular:366.46NF-κB-IN-13
CAS:<p>NF-κB-IN-13 (compound 12) markedly suppresses LPS-induced NF-κB activation and NO synthesis in RAW264.7 macrophages, exhibiting anti-inflammatory properties [1</p>Fórmula:C20H20O5Pureza:98%Cor e Forma:SolidPeso molecular:340.37RIPK1-IN-16
CAS:<p>RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of RIPK1-mediated necroptosis in vivo.</p>Fórmula:C20H19N5O2SPureza:98%Cor e Forma:SolidPeso molecular:393.46Antitumor agent-114
CAS:<p>Antitumor Agent-114, a potent STING (stimulator of interferon genes) agonist, activates immune responses and diminishes tumor size in mouse breast cancer models</p>Fórmula:C39H50F2N10O13P2Pureza:98%Cor e Forma:SolidPeso molecular:966.82IR-Crizotinib
CAS:<p>IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) inhibitor, with an IC50 of 3.381 μM for intracranial</p>Fórmula:C53H57Cl2FIN7OPureza:98%Cor e Forma:SolidPeso molecular:1024.88GW274150 dihydrochloride
CAS:<p>GW274150 (dihydrochloride) is a potent, selective inhibitor of human and rat inducible nitric oxide synthase (iNOS), exhibiting oral activity and NADPH-</p>Fórmula:C8H19Cl2N3O2SPureza:98%Cor e Forma:SolidPeso molecular:292.23Bay 65-1942 (R form)
CAS:<p>Bay 65-1942 R form is the less active R-form of Bay 65-1942. Bay 65-1942 is a selective and ATP-competitive IKKβ inhibitor.</p>Fórmula:C22H25N3O4Pureza:98%Cor e Forma:SolidPeso molecular:395.45Anti-inflammatory agent 65
CAS:<p>Anti-inflammatory agent 65 (compound 29), a Hederagonic acid derivative, exhibits potent activity by inhibiting nitric oxide (NO) release, nuclear translocation</p>Fórmula:C49H71NO6S2Pureza:98%Cor e Forma:SoildPeso molecular:834.22TMV-IN-4
CAS:<p>TMV-IN-4, a TMV inhibitor, enhances plant defense and TMV resilience by interacting with helicase, increasing peroxidase and SOD activity.</p>Fórmula:C18H21NO4Cor e Forma:SolidPeso molecular:315.36MALT1-IN-9
CAS:<p>MALT1-IN-9: potent MALT1 protease inhibitor, IC50 <500 nM in Raji cells, significant anticancer effects.</p>Fórmula:C16H12ClF3N6OCor e Forma:SolidPeso molecular:396.75(R)-MALT1-IN-7
CAS:<p>(R)-MALT1-IN-7 (compound 142a) is a potent inhibitor of MALT1 protease and has potential for cancer research.</p>Fórmula:C19H17F3N8O2SCor e Forma:SolidPeso molecular:478.45FEN1-IN-6
CAS:<p>FEN1-IN-6 (compound 9) is a potent Flap endonuclease-1 (FEN1, IC50 = 10 nM) inhibitor, crucial for DNA damage repair in mammalian cells, and additionally</p>Fórmula:C12H8N2O5S2Pureza:98%Cor e Forma:SolidPeso molecular:324.33IMD-biphenylC
CAS:<p>IMD-biphenylC: New, dual-action imidazoquinolinone dimer; inhibits tumor growth, low inflammation/toxicity.</p>Fórmula:C35H33N5O3Pureza:98%Cor e Forma:SolidPeso molecular:571.67CD73-IN-11
CAS:<p>CD73-IN-11 is a potent inhibitor used to prepare medication for cancer by blocking adenosine production, which fosters tumor growth.</p>Fórmula:C14H10F3N5O2Cor e Forma:SolidPeso molecular:337.26STING-IN-7
CAS:<p>STING-IN-7 (compound 21) serves as a potent inhibitor of the stimulator of interferon genes (STING) pathway, demonstrating an inhibitory concentration (IC50) of</p>Fórmula:C16H14ClN3OPureza:98%Cor e Forma:SolidPeso molecular:299.76PROTAC IRAK4 degrader-8
CAS:<p>PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 of 15.5 nM [1].</p>Fórmula:C43H50ClF2N11O5Pureza:98%Cor e Forma:SolidPeso molecular:874.38hnNOS-IN-2
CAS:<p>Compound 17, also known as hnNOS-IN-2, is an inhibitor of human neuronal nitric oxide synthase (hnNOS) that exhibits good metabolic stability.</p>Fórmula:C18H23F2N3Pureza:98%Cor e Forma:SolidPeso molecular:319.39RIP1 kinase inhibitor 4
CAS:<p>RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 of ≤ 1000 nM [1].</p>Fórmula:C23H23N5Pureza:98%Cor e Forma:SolidPeso molecular:369.46Anti-inflammatory agent 46
CAS:<p>Anti-inflammatory agent 46 (compound 7h), exhibiting nitric oxide (NO) inhibitory properties, demonstrates a high affinity for iNOS through low binding energies</p>Fórmula:C24H19FN2O3SPureza:98%Cor e Forma:SolidPeso molecular:434.48STING-IN-5
CAS:<p>STING-IN-5 suppresses NO synthesis in macrophages, inhibits STING pathway with IC50 of 1.15 μM, and may aid anti-inflammatory and sepsis research.</p>Fórmula:C47H67NO9S2Pureza:98%Cor e Forma:SolidPeso molecular:854.17RIPK2-IN-3
CAS:<p>RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor with anti-inflammatory and anticancer activities, useful for research on immune diseases and cancer.</p>Fórmula:C25H22N4O2Pureza:99.57%Cor e Forma:SolidPeso molecular:410.47Trovafloxacin mesylate
CAS:<p>Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).</p>Fórmula:C21H19F3N4O6SPureza:99.18%Cor e Forma:SolidPeso molecular:512.46IMD-vanillin
CAS:<p>IMD-vanillin is a novel compound characterized as an imidazoquinolinone-derived dimer with NF-κB immunomodulatory properties.</p>Fórmula:C37H45N7O4Pureza:98%Cor e Forma:SolidPeso molecular:651.8NLRP3-IN-9
CAS:<p>NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.</p>Fórmula:C12H13ClO3Pureza:99.64%Cor e Forma:SolidPeso molecular:240.68CCG-63802
CAS:<p>CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.</p>Fórmula:C26H18N4O2SPureza:90%Cor e Forma:SolidPeso molecular:450.51Benoxaprofen
CAS:<p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>Fórmula:C16H12ClNO3Pureza:98.87%Cor e Forma:SolidPeso molecular:301.72IKK-IN-1
CAS:IKK-IN-1 is an inhibitor of IKK.Fórmula:C22H26ClN3O4Pureza:98%Cor e Forma:SolidPeso molecular:431.91PK68
CAS:<p>PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.</p>Fórmula:C22H24N4O3SPureza:98.09% - 99.64%Cor e Forma:SolidPeso molecular:424.52Galectin-3 antagonist 2
CAS:<p>Galectin-3: a lectin aiding BCP-ALL cell migration & drug resistance.</p>Fórmula:C22H23NO10Pureza:98%Cor e Forma:SolidPeso molecular:461.42TLR9-IN-1
CAS:<p>TLR9-IN-1: selective, potent human TLR9 inhibitor (IC50: 7 nM), useful for researching immune-related diseases.</p>Fórmula:C23H31N7OCor e Forma:SolidPeso molecular:421.544-CPPC
CAS:<p>4-CPPC inhibits MIF-2 (IC50=27μM), not MIF-1; blocks MIF-2/CD74 binding and MIF-2-induced ERK1/2 in fibroblasts.</p>Fórmula:C14H9NO6Pureza:97.50% - 98.03%Cor e Forma:SolidPeso molecular:287.22Fendosal
CAS:<p>Fendosal (HP-129), NSAID, 6.9-9.5x stronger than aspirin in chronic inflammation models.</p>Fórmula:C25H19NO3Pureza:99.3%Cor e Forma:SolidPeso molecular:381.423M-011
CAS:<p>3M-011: potent TLR7/8 agonist, cytokine inducer, enhances radiotherapy, fights H3N2, and has anti-tumor effects.</p>Fórmula:C18H25N5O3SPureza:98%Cor e Forma:SolidPeso molecular:391.49BD-AcAc 2
CAS:<p>BD-AcAc 2 (Ketone Ester) is a ketone monoester and can be used as a source of oral nutritional ketones.</p>Fórmula:C8H16O4Pureza:99.62%Cor e Forma:SolidPeso molecular:176.21IL-17A antagonist 3
CAS:<p>IL-17A antagonist 3 is an IL-17A antagonist.</p>Fórmula:C33H33ClN6O4Pureza:98%Cor e Forma:SolidPeso molecular:613.11GGTI 2147
CAS:<p>GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.</p>Fórmula:C28H30N4O3Pureza:98.69%Cor e Forma:SolidPeso molecular:470.56GW274150 phosphate
CAS:<p>GW274150 phosphate is a selective, orally active iNOS inhibitor with an IC50 of 0.2 μM. It mitigates experimental renal ischaemia-reperfusion injury.</p>Fórmula:C8H20N3O6PSPureza:98%Cor e Forma:SolidPeso molecular:317.3Dexamethasone palmitate
CAS:<p>DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist & anti-inflammatory.</p>Fórmula:C38H59FO6Pureza:99.28%Cor e Forma:SolidPeso molecular:630.87Aminoguanidine hemisulfate
CAS:<p>Aminoguanidine hemisulfate, an inhibitor of nitric oxide synthases (NOS) and reactive oxygen species (ROS), effectively suppresses ANE-induced ROS production in</p>Fórmula:CH6N4H2SO4Pureza:98%Cor e Forma:SolidPeso molecular:123.115Stobadine
CAS:<p>Stobadine, a potent antioxidant, safeguards endoplasmic reticulum (ER) membrane fluidity against free radical-induced changes.</p>Fórmula:C13H18N2Pureza:98%Cor e Forma:SolidPeso molecular:202.3Lipid peroxidation inhibitor 1
CAS:<p>Lipid peroxidation inhibitor 1 is an inhibitor of lipid peroxidation (IC50: 0.07 μM).</p>Fórmula:C24H32N2OPureza:98%Cor e Forma:SolidPeso molecular:364.52JNJ-67856633
CAS:<p>JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease .</p>Fórmula:C20H11F6N5O2Pureza:99.87%Cor e Forma:SolidPeso molecular:467.32Dapsone hydroxylamine
CAS:<p>Dapsone hydroxylamine (DDS-NOH) promotes methemoglobinemia, impedes catalase (CAT) activity, and suppresses the generation of reactive oxygen species, while</p>Fórmula:C12H12N2O3SPureza:98%Cor e Forma:SolidPeso molecular:264.3HBF-0259
CAS:HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells.Fórmula:C16H12Cl2FN5Pureza:98.07% - 99.42%Cor e Forma:SolidPeso molecular:364.2α-Pyridoin
CAS:<p>α-Pyridoin (α-pyridoin) is an enediol (enediol) compound that acts as a unique antioxidant.</p>Fórmula:C12H12N2O2Cor e Forma:SolidPeso molecular:216.24TIM-3-IN-2
CAS:<p>TIM-3-IN-2 is a Tim3 inhibitor that inhibits the action of TIM-3.TIM-3-IN-2 reverses TIM-3-mediated pro-inflammatory cytokine effects.</p>Fórmula:C25H23N3O6Pureza:98.93%Cor e Forma:SolidPeso molecular:461.47IRAK4-IN-28
CAS:<p>IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a Kd of 0.58 nM for the target enzyme.</p>Fórmula:C27H31N9O3Pureza:98%Cor e Forma:SolidPeso molecular:529.59NLRP3-IN-17
CAS:<p>NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM.</p>Fórmula:C21H22N4O2SPureza:98%Cor e Forma:SolidPeso molecular:394.49Nrf2-IN-1
CAS:<p>Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor. Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML).</p>Fórmula:C21H22ClN3O2Pureza:95.00% - 99.68%Cor e Forma:SolidPeso molecular:383.87STING agonist-3
CAS:<p>STING agonist-3: non-nucleotide, selective, anti-tumor with pEC50=7.5, pIC50=9.5, could enhance cancer therapy.</p>Fórmula:C37H42N12O6Pureza:98%Cor e Forma:SolidPeso molecular:750.81STING agonist-10
CAS:<p>STING agonist-10 is a potent activator of the STING small molecule cyclic urea class (EC50: 2600 nM).STING activation is a highly promising immunotherapy.</p>Fórmula:C25H20ClF4N3O2Cor e Forma:SolidPeso molecular:505.89Keap1-Nrf2-IN-16
CAS:<p>Keap1-Nrf2-IN-16 is a biologically active peptide with KEAP1 binding activity.</p>Fórmula:C73H114N16O26Cor e Forma:SolidPeso molecular:1631.78Arginase inhibitor 1
CAS:<p>Arginase inhibitor 1 is a potent inhibitor of human arginases I and II (IC50s: 223 and 509 nM).</p>Fórmula:C13H27BN2O4Cor e Forma:SolidPeso molecular:286.18Factor B-IN-2
CAS:<p>Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.</p>Fórmula:C25H32N2O4Cor e Forma:SolidPeso molecular:424.53cGAS-IN-1
CAS:<p>cGAS-IN-1 (compound C20), a flavonoid that acts as a Cyclic GMP-AMP Synthase (cGAS) inhibitor, demonstrates IC50 values of 2.28 μM for human cGAS and 1.44 μM</p>Fórmula:C18H19NO8Cor e Forma:SolidPeso molecular:377.35Dimethoxycurcumin
CAS:Dimethoxycurcumin is a stable curcumin analog causing epigenetic shifts in leukemia cells, affecting gene expression.Fórmula:C23H24O6Pureza:99.87%Cor e Forma:SolidPeso molecular:396.43CD73-IN-4
CAS:<p>CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor</p>Fórmula:C16H23ClN5O7PPureza:98.61%Cor e Forma:SolidPeso molecular:463.81BDW568
CAS:<p>BDW568, a prodrug of BDW-OH, serves as a stimulator of interferon genes (STING) agonist.</p>Fórmula:C12H12N4O2S2Cor e Forma:SolidPeso molecular:308.38IFN α-IFNAR-IN-1 hydrochloride
CAS:<p>IFN alpha-IFNAR-IN-1 HCl blocks IFN-α/IFNAR binding; IC50 2-8 μM in BM-pDCs' MVA-induced IFN-α response.</p>Fórmula:C18H18ClNSPureza:99.77%Cor e Forma:SolidPeso molecular:315.86Leteprinim
CAS:<p>Leteprinim (AIT 082 acid) is an hypoxanthine derivative that stimulates in vitro neurite outgrowth and the production of adenosine and neurotrophins from</p>Fórmula:C15H13N5O4Pureza:99.08%Cor e Forma:SolidPeso molecular:327.29Veledimex racemate
CAS:<p>Veledimex racemate, the racemic form of veledimex, is an orally available, small-molecule ligand that activates the RheoSwitch Therapeutic System.</p>Fórmula:C27H38N2O3Pureza:98%Cor e Forma:SolidPeso molecular:438.6ACHP Hydrochloride
CAS:<p>ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.</p>Fórmula:C21H25ClN4O2Pureza:99.83%Cor e Forma:SolidPeso molecular:400.9ML-090
CAS:<p>ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).</p>Fórmula:C14H10N4Pureza:98.55%Cor e Forma:SolidPeso molecular:234.26CCT374705
CAS:<p>CCT374705, an orally active BCL6 inhibitor, exhibits potent antiproliferative effects in vitro and effectively inhibits tumor growth in a lymphoma xenograft</p>Fórmula:C21H18ClF3N4O2Cor e Forma:SolidPeso molecular:450.84TLR7 agonist 23
CAS:<p>TLR7 agonist23 (compound 12b) is a potent agonist of Toll-like receptor-7 (TLR7), with an EC50 value of 0.15 uM. It is suitable for research in immune diseases.</p>Fórmula:C21H22N4O2Cor e Forma:SolidPeso molecular:362.42GBT1118
CAS:<p>GBT1118 is an orally active allosteric modulator of haemoglobin oxygen affinity, enhancing tolerance to acute severe hypoxia and suitable for hypoxia research.</p>Fórmula:C19H20N2O4Pureza:99.69%Cor e Forma:SolidPeso molecular:340.37MALT1-IN-6
CAS:<p>MALT1-IN-6 is a MALT1 protease inhibitor (Ki: 9 nM) that exhibits anticancer activity.</p>Fórmula:C18H12Cl2F3N9OCor e Forma:SolidPeso molecular:498.25(Rac)-BAY-985
CAS:<p>(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy.</p>Fórmula:C27H30F3N9OPureza:98%Cor e Forma:SolidPeso molecular:553.583'-Azido-3'-deoxy-5-methylcytidine
CAS:<p>3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase(EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-related</p>Fórmula:C10H14N6O4Pureza:99.55%Cor e Forma:SolidPeso molecular:282.26CD38 inhibitor 2
CAS:<p>CD38 inhibitor 2 is a potent CD38 inhibitor ( IC 50 = 0.01 ~ 0.1 μΜ).</p>Fórmula:C19H24N6O3Cor e Forma:SolidPeso molecular:384.43h-NTPDase-IN-3
CAS:<p>h-NTPDase-IN-3 is an h-NTPDase inhibitor that inhibits h-NTPDase1, h-NTPDase2, h-NTPDase3 and h-NTPDase8.</p>Fórmula:C16H10N4SPureza:98.24%Cor e Forma:SolidPeso molecular:290.34Glabrescone C
CAS:<p>Glabrescone C exhibits strong anti-inflammatory properties through direct binding to IKKα/β.</p>Fórmula:C19H22O7Cor e Forma:SolidPeso molecular:362.37(R)-IL-17 modulator 4
CAS:<p>(R)-IL-17 modulator 4, an R-isomer prodrug of IL-17 modulator 1, is potent and taken orally.</p>Fórmula:C27H34N6O2Cor e Forma:SolidPeso molecular:474.6Glu-urea-Glu-NHS ester
CAS:<p>Compound 21, Glu-urea-Glu-NHS ester, an activated N-hydroxysuccinamide (NHS) ester derivative of Glu-urea-Glu, serves as a pharmacophore for conjugation to prostate specific membrane antigen (PSMA) inhibitors [1].</p>Fórmula:C27H43N3O11Cor e Forma:SolidPeso molecular:585.64TLR7 agonist 14
CAS:<p>Compound 17b, a TLR7 agonist also known as TLR7 agonist 14, exhibits high potency with an EC50 of 18 nM.</p>Fórmula:C29H36N6O3Cor e Forma:SolidPeso molecular:516.63FCE-27164
CAS:<p>FCE-27164 inhibits PDGF-β and IL-7 receptor binding, potentially modulating inflammatory and immune responses for therapeutic applications.</p>Fórmula:C45H34N10Na6O23S6Pureza:96.04%Cor e Forma:SolidPeso molecular:1413.11DNA polymerase-IN-1
CAS:<p>DNA polymerase-IN-1 exhibits antiproliferative activity against tumor cells and inhibits Taq DNA polymerase as a DNA polymerase inhibitor.</p>Fórmula:C10H7ClO4Pureza:99.16%Cor e Forma:SolidPeso molecular:226.61CAY10464
CAS:<p>CAY10464 (AHR antagonist 7) is an AHR antagonist for the study of cancer and metabolic diseases.</p>Fórmula:C15H12Cl2OPureza:99.96%Cor e Forma:SolidPeso molecular:279.16TLR7 agonist 15
CAS:<p>TLR7 agonist 15 (compound 16b) is a potent activator of mouse macrophages and hPBMCs, demonstrating an EC50 of 18 nM.</p>Fórmula:C26H31N5OCor e Forma:SolidPeso molecular:429.56Tyrosinase-IN-22
CAS:<p>Tyrosinase-IN-22 (compound 4) serves as a potent inhibitor for tyrosinase substrates, namely L-tyrosine and L-dopa, exhibiting inhibitory concentrations (IC50s) of 60 nM and 30 nM, respectively. Additionally, it demonstrates significant antioxidant and anti-melanogenic properties, making it suitable for related research endeavors [1].</p>Fórmula:C7H5ClN2SCor e Forma:SolidPeso molecular:184.64GSK840
CAS:<p>GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinase</p>Fórmula:C21H23N3O3Pureza:99.7%Cor e Forma:SolidPeso molecular:365.43TLR7 agonist 16
CAS:<p>TLR7 agonist 16 (compound 16d) is a potent activator of TLR7 with an EC50 value of 18 nM.</p>Fórmula:C25H29N5O2Cor e Forma:SolidPeso molecular:431.53AVP-13358
CAS:<p>AVP-13358: a CD23/IgE inhibitor for treating immune, infection, and ENT disorders.</p>Fórmula:C30H29N5O2Pureza:98.42%Cor e Forma:SolidPeso molecular:491.58ERDRP-0519
CAS:<p>ERDRP-0519 is an oral measles polymerase inhibitor, preventing disease in monkeys, with potent nanomolar efficacy against morbilliviruses.</p>Fórmula:C23H30F3N5O4SPureza:98.64% - 98.71%Cor e Forma:SolidPeso molecular:529.58LTβR-IN-1
CAS:<p>LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor.</p>Fórmula:C18H16N4O2Pureza:98.93%Cor e Forma:SolidPeso molecular:320.35GW274150
CAS:<p>GW274150: selective oral iNOS inhibitor (Kd=40 nM), low activity on eNOS/nNOS, protective in acute lung injury.</p>Fórmula:C8H17N3O2SPureza:96.43%Cor e Forma:SolidPeso molecular:219.3Netakimab
CAS:<p>Netakimab (BCD 085) is a monoclonal antibody targeting interleukin-17A and can be used to study spondyloarthritis.</p>Pureza:95%Cor e Forma:LiquidPeso molecular:145.74 kDaIL-17 modulator 4
CAS:<p>IL-17 modulator 4 is a prodrug of IL-17 modulator 1, which acts as a potent modulator of IL-17.Cost-effective and quality-assured.</p>Fórmula:C27H34N6O2Pureza:99.59%Cor e Forma:SolidPeso molecular:474.6ADS032
CAS:<p>ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity for the study of respiratory inflammation or infection.</p>Fórmula:C22H29NO4SPureza:98.37%Cor e Forma:SolidPeso molecular:403.54Usnoflast
CAS:<p>Usnoflast (ZYIL1) is an NLRP3 inhibitor, inhibiting NLRP3 inflammasome activation, used in neurological disease research.</p>Fórmula:C21H29N3O3SPureza:98.79%Cor e Forma:SolidPeso molecular:403.54Sembragiline
CAS:<p>Sembragiline (EVT-302) is a selective MAO-B inhibitor for the study of Alzheimer's disease (AD).</p>Fórmula:C19H19FN2O3Pureza:99.49% - 99.49%Cor e Forma:SolidPeso molecular:342.36Iptacopan
CAS:<p>Iptacopan (LNP023) is an inhibitor with high affinity to factor B, with a KD value of 7.9 nM and an IC50 value of 10 nM. Cost-effective and quality-assured.</p>Fórmula:C25H30N2O4Pureza:99.07% - >99.99%Cor e Forma:SolidPeso molecular:422.52Oditrasertib
CAS:<p>Oditrasertib, a RIPK1 inhibitor characterized by an IC50 value below 100 nM, is employed in inflammation research.</p>Fórmula:C14H15F2N3O2Pureza:98.65% - 99.65%Cor e Forma:SolidPeso molecular:295.28Supercinnamaldehyde
CAS:<p>Supercinnamaldehyde is a potent activator of transient receptor potential ankyrin 1 (TRPA1), exhibiting an EC50 of 0.8 μM, and induces activation of TRPA1 ion</p>Fórmula:C12H11NO2Pureza:98.89%Cor e Forma:SolidPeso molecular:201.22Antiviral agent 34
CAS:<p>Antiviral Agent 34 is an antiviral compound that inhibits influenza virus and inhibits the proliferation of influenza virus by modulating RNA polymerase.</p>Fórmula:C29H33N3O2SPureza:99.51%Cor e Forma:SoildPeso molecular:487.66CU-CPD107
CAS:<p>CU-CPD107 selectively activates TLR8 and ssRNA, inhibits TLR8 with R848 (IC50=13.7 μM), and coactivates with ssRNA.</p>Fórmula:C16H21IN2O2Pureza:98%Cor e Forma:SolidPeso molecular:400.25Xanthine oxidase-IN-10
CAS:<p>Xanthine oxidase-IN-10 (XO8 analog) is a xanthine oxidase (XO) inhibitor for the study of gout.</p>Fórmula:C10H8N2OSPureza:99.16%Cor e Forma:SolidPeso molecular:204.25Piflufolastat
CAS:<p>Piflufolastat (DCFPYL) is a PET imaging agent for prostate cancer PSMA.</p>Fórmula:C18H23FN4O8Pureza:98.98%Cor e Forma:SolidPeso molecular:442.4Nrf2-IN-3
CAS:<p>Nrf2-IN-3 is an NRF2 inhibitor that selectively sensitizes xenografts of mouse mKEAP1 cancer cells to cisplatin.</p>Fórmula:C22H26N4O4SPureza:98.07%Cor e Forma:SolidPeso molecular:442.53(±)-CPSI-1306
CAS:<p>(±)-CPSI-1306 (2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one) is a macrophage migration inhibitory factor (MIF) antagonist and can</p>Fórmula:C15H16F2N2O3Pureza:97.46%Cor e Forma:SolidPeso molecular:310.3GB1107
CAS:<p>GB1107 is an effective and selective Galectin-3 inhibitor with a Kd of 37 nM.</p>Fórmula:C20H16Cl2F3N3O4SPureza:98.33% - 99.87%Cor e Forma:SolidPeso molecular:522.32ABR-238901
CAS:<p>ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products</p>Fórmula:C11H9BrClN3O4SPureza:98.63% - 98.71%Cor e Forma:SolidPeso molecular:394.63RIPK1-IN-4
CAS:<p>RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to a DLG-out inactive form of RIP1 (IC50s</p>Fórmula:C23H23N5O2Pureza:99.94%Cor e Forma:SolidPeso molecular:401.46cGAS-IN-4
CAS:<p>cGAS-IN-4 (Compound 36) is an orally active inhibitor of cyclic GMP-AMP synthase (cGAS) with IC50 values of 32 nM for human cGAS (h-cGAS) and 5.8 nM for mouse cGAS (m-cGAS). In THP-1 cells, cGAS-IN-4 inhibits cGAMP with an IC50 of 60 nM, enhancing cellular potency. Additionally, cGAS-IN-4 exhibits anti-inflammatory effects in a mouse model of Concanavalin A-induced acute liver injury.</p>Fórmula:C19H18Cl2N4O3Cor e Forma:SolidPeso molecular:421.277IRAK4-IN-15
CAS:<p>IRAK4-IN-15: selective IRAK4 inhibitor, IC50 0.002 μM, good PK, low clearance, synergizes with Acalabrutinib in MyD88/CD79 mutant ABC-DLBCL.</p>Fórmula:C25H29FN10Cor e Forma:SolidPeso molecular:488.56Creatine ethyl ester
CAS:<p>Creatine ethyl ester (CEE) is a readily available form of creatine commonly used in supplements. It can upregulate TLRs (TLR2, 3, 4, and TLR7) over a short period.</p>Fórmula:C6H13N3O2Cor e Forma:SolidPeso molecular:159.186DPP4-In hydrochloride
CAS:<p>DPP4-In (hydrochloride) is an inhibitor of dipeptidyl peptidase 4 (DPP4) that effectively reduces the expression of DPP4.</p>Fórmula:C14H21ClN4O2Cor e Forma:SolidPeso molecular:312.8Cyclic-di-GMP sodium
<p>c-di-GMP sodium: STING activator, regulates bacteria biofilm, motility, virulence.</p>Fórmula:C20H24N10NaO14P2Cor e Forma:SolidPeso molecular:713.08464EGR-1-IN-3
CAS:<p>EGR-1-IN-3 (Compound 36) is an inhibitor of early growth response 1 (EGR-1) binding to DNA. It effectively suppresses the binding of EGR-1 to DNA and the expression of inflammation-related genes (such as TSLP, IL-31, IL-6, and CCL2) induced by TNFα. This compound is applicable to the study of inflammatory diseases.</p>Fórmula:C31H31N3O6SCor e Forma:SolidPeso molecular:573.659FAPI-74
CAS:<p>FAPI-74 is a PET (positron emission tomography) tracer involved in early FAPI-PET imaging.FAPI-74 can be used to study cancer tumors and degenerative diseases.</p>Fórmula:C36H49N9O8Cor e Forma:SolidPeso molecular:735.83Amilo-5MER
CAS:<p>Amilo-5MER (5-MP) is an orally active and selective inhibitor of serum amyloid A (SAA). It specifically suppresses the release of pro-inflammatory cytokines IL-6 and IL-1β in SAA-activated cells. Amilo-5MER reduces chronic inflammation and alleviates symptoms of diseases such as rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and multiple sclerosis (MS). It holds potential for research in autoimmune and chronic inflammatory diseases.</p>Fórmula:C23H40N6O9SCor e Forma:SolidPeso molecular:576.664Ocadusertib
CAS:<p>Ocadusertib is an effective inhibitor of the serine/threonine kinase receptor-interacting protein kinase 1 (RIPK1).</p>Fórmula:C25H25N5O4Cor e Forma:SolidPeso molecular:459.50AhR agonist 8
CAS:<p>Compound 9, also known as AhR agonist 8, effectively activates the Aryl Hydrocarbon Receptor (AhR) with an EC50 of 0.154 nM. This compound is utilized in researching psoriasis and atopic dermatitis.</p>Fórmula:C17H15FN4OCor e Forma:SolidPeso molecular:310.33TNFα activity modulator 3
CAS:<p>TNFα Activity Modulator 3 (example 6) is a molecule that regulates TNF activity by inhibiting TNFα-induced NF-κB activation, making it applicable for related research.</p>Fórmula:C27H24F2N6O2Cor e Forma:SolidPeso molecular:502.52NLRP3-IN-44
CAS:<p>NLRP3-IN-44 (compound P33), an orally active (approximately 62%) and potent inhibitor of NLRP3, exhibits a dissociation constant (K D) of 17.5 nM. This compound is crucial in the research of diseases mediated by the NLRP3 inflammasome.</p>Fórmula:C25H30N4O3Cor e Forma:SolidPeso molecular:434.53GTCpFE
CAS:GTCpFE, a compound synthesized from Dimethyl fumarate (DMF) and Aspirin (ASA), inhibits IKKα/β in the NF-κB pathway, exhibiting anti-inflammatory activity by preventing p65 from entering the nucleus. It selectively inhibits cancer stem cell (CSC) activity by reducing the growth of mammospheres and the expression of the CD44+CD24- immune phenotype. Furthermore, GTCpFE targets breast cancer stem cells, crucial in aggressive cancer phenotypes that depend on NFκB and PGE2.Fórmula:C22H20O8Cor e Forma:SolidPeso molecular:412.39Panaxcerol B
CAS:<p>Panaxcerol B, a monogalactosyl monoacylglycerol, exhibits an IC50 value of 59.4 μM against NO production in LPS-stimulated RAW264.7 cells.</p>Fórmula:C27H46O9Cor e Forma:SolidPeso molecular:514.65SBI-0640726
CAS:<p>SBI-0640726, an eIF4G1 inhibitor, exhibits antiproliferative activity against melanoma. It disrupts the eIF4F translation initiation complex by inhibiting the AKT and NF-kB signaling pathways. Additionally, SBI-0640726 inhibits the growth of melanoma with NRAS and BRAF mutations in vitro.</p>Fórmula:C23H15ClN2O2Cor e Forma:SolidPeso molecular:386.83LD03-DEX
CAS:LD03-DEX is a precursor compound of dexamethasone, characterized by its immunosuppressive activity.Fórmula:C44H65FO8Peso molecular:740.98Indeno[1,2,3-cd]pyrene
CAS:<p>Indeno[1,2,3-cd]pyrene, a polycyclic aromatic hydrocarbon, exhibits moderate cytotoxicity to human alveolar epithelial cells (HPAEpiC). Additionally, it enhances allergic pulmonary inflammation responses through the activation of the aryl hydrocarbon receptor.</p>Fórmula:C22H12Cor e Forma:SolidPeso molecular:276.33UM-3006
CAS:UM-3006 is a potent TLR7/8 agonist that enhances immune responses by activating the TLR signaling pathway. This compound holds significant research and application potential in the fields of vaccine adjuvants and immune diseases.Fórmula:C20H34N6O2Peso molecular:390.52
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