Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(148 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(60 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(444 produtos)
- NOD(17 produtos)
- NOS(63 produtos)
- Nrf2(79 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3045 produtos de "Imunologia e Inflamação"
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Anifrolumab
CAS:<p>Anifrolumab（MEDI-546） is a potent type I interferon (IFN) receptor antagonist, a human monoclonal antibody that targets IFN.Anifrolumab inhibits the activity of</p>Pureza:> 95% - > 95%Cor e Forma:LiquidPeso molecular:144.92 kDaArticaine hydrochloride
CAS:<p>Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.</p>Fórmula:C13H21ClN2O3SPureza:99.76%Cor e Forma:White Crystalline PowderPeso molecular:320.84(3E,4S)-3-{2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-decahydronaphthalen-1-yl]ethylidene}-4-hydroxyoxolan-2-one
CAS:Fórmula:C20H30O5Pureza:98%Cor e Forma:SolidPeso molecular:350.4492S-Nitroso-N-acetyl-DL-penicillamine
CAS:<p>S-Nitroso-N-acetyl-DL-penicillamine (SNAP) acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and .</p>Fórmula:C7H12N2O4SPureza:97.42% - >99.99%Cor e Forma:Green Crystalline SolidPeso molecular:220.25GSK3145095
CAS:<p>GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential immunomodulatory activities and antineoplastic.</p>Fórmula:C20H17F2N5O2Pureza:99.50%Cor e Forma:SolidPeso molecular:397.38Sabatolimab
CAS:<p>Sabatolimab (MBG453) is a humanized IgG4 antibody that inhibits TIM-3 to modulate immunity and shows promise as an immunosuppressant.</p>Pureza:> 95% - > 95%Cor e Forma:LiquidPeso molecular:145 kDa (average)4-Hydroxychalcone
CAS:<p>4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.</p>Fórmula:C15H12O2Pureza:99.75%Cor e Forma:Yellow PowderPeso molecular:224.25TBK1/IKKε-IN-2
CAS:<p>TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.</p>Fórmula:C26H27N5O3Pureza:98.89%Cor e Forma:SolidPeso molecular:457.52Diclofenac Amide
CAS:<p>Diclofenac Amide is used as a intermediates of Diclofenac.</p>Fórmula:C14H9Cl2NOPureza:98.80%Cor e Forma:SolidPeso molecular:278.13Itepekimab
CAS:<p>Itepekimab (REGN-3500), a potent IL-33 monoclonal antibody, may help study asthma by reducing airway inflammation.</p>Pureza:92.8%Cor e Forma:LiquidPeso molecular:144.63kDaTheralizumab
CAS:<p>Theralizumab (TGN1412) is a monoclonal antibody for treating leukemia and arthritis by stimulating T cells.</p>Pureza:95%Cor e Forma:LiquidAdrenalone hydrochloride
CAS:<p>Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.</p>Fórmula:C9H11NO3·HClPureza:99.94%Cor e Forma:SolidPeso molecular:217.65Oxiracetam
CAS:<p>Oxiracetam (ISF2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is utilized for the treatment of cognitive impairments.</p>Fórmula:C6H10N2O3Pureza:99.67%Cor e Forma:White Crystalline PowderPeso molecular:158.16Sodium laureth sulfate
CAS:<p>Sodium laureth sulfate is an anionic surfactant known for strong cleaning, wetting, emulsifying, dispersing, and foaming abilities.</p>Fórmula:C14H30NaO5SPureza:70% - ≥98%Cor e Forma:SolidPeso molecular:333.44Nialamide
CAS:<p>Nialamide (Nialamid) is an MAO inhibitor that is used as an antidepressive agent.</p>Fórmula:C16H18N4O2Pureza:90.30% - 93.91%Cor e Forma:White Crystalline Powder SolidPeso molecular:298.344-Hydroxyantipyrine
CAS:<p>4-Hydroxyantipyrine is formed during oxidative deamination of aminopyrine.</p>Fórmula:C11H12N2O2Pureza:99.85%Cor e Forma:SolidPeso molecular:204.23Nisoldipine
CAS:<p>Nisoldipine (BAY-k 5552) is a dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent.</p>Fórmula:C20H24N2O6Pureza:98.79% - 99.57%Cor e Forma:SolidPeso molecular:388.41Theophylline
CAS:<p>Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central</p>Fórmula:C7H8N4O2Pureza:99.65% - 99.98%Cor e Forma:White Solid PowderPeso molecular:180.16N-Demethylricinine
CAS:<p>N-Demethylricinine (4-Methoxy-2-oxo-1,2-dihydro-pyridine-3-carbonitrile) was reported as xanthine oxidase inhibitor.</p>Fórmula:C7H6N2O2Pureza:99.11%Cor e Forma:SolidPeso molecular:150.13AB-680
CAS:<p>AB-680 is a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity, displays >10,000-</p>Fórmula:C20H24ClFN4O9P2Pureza:97.51% - 97.98%Cor e Forma:SolidPeso molecular:580.82SM-276001
CAS:<p>SM-276001 is a potent selective agonist of TLR7,and is an orally active interferon (IFN) inducer.</p>Fórmula:C16H21N7OPureza:99.91%Cor e Forma:SolidPeso molecular:327.38Erdosteine
CAS:<p>Erdosteine (RV 144), a mucolytic thiol, modulates mucus and aids expectoration, reduces cough, and protects lungs from smoke damage.</p>Fórmula:C8H11NO4S2Pureza:99.43% - 99.94%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:249.31Aluminum Hydroxide
CAS:<p>Aluminum Hydroxide: oral adjuvant, aids vaccine potency, enhances immune response.</p>Fórmula:AlH3O3Pureza:98%Cor e Forma:White Solid PowderPeso molecular:78Cobolimab
CAS:<p>Cobolimab (TSR-022) is a TIM-3 antibody with IC50 of 0.4464 nM, showing antitumor effects in melanoma and liver cancer studies.</p>Pureza:> 95%Cor e Forma:LiquidPeso molecular:142.84 kDaXanthone
CAS:<p>Xanthone (Xanthenone) is currently used as ovicide for codling moth eggs and as a larvicide.</p>Fórmula:C13H8O2Pureza:99.44% - 99.86%Cor e Forma:Off-White PowderPeso molecular:196.2Levilimab
CAS:<p>Levilimab (BCD-089) is a fully humanized human monoclonal antibody targeting membrane-bound and soluble IL-6 R for the study of rheumatoid arthritis.</p>Pureza:97.8% (SDS-PAGE); 97.3% (SEC-HPLC) - 97.8% (SDS-PAGE); 97.3% (SEC-HPLC)Cor e Forma:LiquidLHF-535
CAS:<p>LHF-535 is an antiviral compound. It has EC50s of <1 μM, <1 μM, <1 μM, and 1-10 μM for Lassa, Machupo, Junin, and VSVg virus, respectively.</p>Fórmula:C27H28N2O2Pureza:99.60%Cor e Forma:SolidPeso molecular:412.52(+/-)-2-(6-Methoxy-2-naphthyl)propionic acid
CAS:Fórmula:C14H14O3Pureza:98%Cor e Forma:SolidPeso molecular:230.2592Brodalumab
CAS:<p>Brodalumab (AMG 827), a human IgG2 monoclonal antibody, inhibits IL-17R, treating psoriasis.</p>Pureza:98.3%Cor e Forma:LiquidPeso molecular:144.06 kDaColtuximab
<p>Coltuximab is a humanized anti-CD19 antibody that can be used to synthesize ADC compounds (Coltuximab Ravtansine).</p>Pureza:95.3% (SDS-PAGE); 98.6% (SEC-HPLC) - 95.3% (SDS-PAGE); 98.6% (SEC-HPLC)Cor e Forma:Odour LiquidIbritumomab
<p>Ibritumomab is a murine-derived anti-CD20 monoclonal antibody that kills tumor cells by forming free radicals in target cells and surrounding tissues.</p>Pureza:96% (SDS-PAGE); 95.9% (SEC-HPLC) - 96% (SDS-PAGE); 95.9% (SEC-HPLC)Cor e Forma:Odour LiquidAntibacterial agent 273
<p>Antibacterialagent 273 (Compound 15e) is an antimicrobial agent targeting bacterial cell membranes, effectively disrupting them with a MIC value of 4 μg/mL against Staphylococcus aureus. It causes the leakage of intracellular nucleic acids and proteins, inhibits bacterial metabolic activity, and induces the accumulation of reactive oxygen species (ROS) within bacteria. Antibacterialagent 273 is applicable in research on infections caused by Staphylococcus aureus.</p>Cor e Forma:Odour SolidC12-rrw-NH2
<p>C12-rrw-NH2 (Compound Lip7) is an antimicrobial agent effective against Gram-positive bacteria, particularly demonstrating significant activity against Methicillin-resistant Staphylococcus aureus (MRSA). It induces bacterial cell death by depolarizing the bacterial cell membrane, disrupting membrane integrity, causing nucleic acid and protein leakage, and promoting the generation of Reactive Oxygen Species (ROS). C12-rrw-NH2 is applicable in research focused on developing highly stable antimicrobial peptides.</p>Fórmula:C35H58N10O5Cor e Forma:SolidPeso molecular:698.9ABTIM3-hum03
<p>ABTIM3-hum03 is a humanized anti-TIM3 blood-brain barrier shuttling monoclonal antibody.</p>Pureza:97.6% (SDS-PAGE); 98.6% (SEC-HPLC) - 97.6% (SDS-PAGE); 98.6% (SEC-HPLC)Cor e Forma:Odour LiquidCOX-2-IN-52
<p>COX-2-IN-52 (Compound 5l) is an orally active and selective COX-2 inhibitor with an IC50 of 54 nM. It can suppress the release of NO in cells, exhibiting anti-inflammatory properties. COX-2-IN-52 offers high gastrointestinal safety and is suitable for research on oral anti-inflammatory drugs.</p>Fórmula:C16H13IN4O4S2Cor e Forma:SolidPeso molecular:516.333SjDX5-271
CAS:<p>SjDX5-271 is a 3 kDa peptide that inhibits the TLR4/MyD88/NF-κB signaling pathway. It induces cell polarization, alleviates liver inflammation, and protects mice from liver ischemia-reperfusion injury.</p>Fórmula:C137H215N47O49SCor e Forma:SolidPeso molecular:3336.52Nemvaleukin alfa
CAS:<p>Nemvaleukin alfa (ALKS 4230) is an interleukin 2 fusion protein that is a selective agonist of the medium-affinity IL-2 receptor.</p>Pureza:98.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 98.4% (SDS-PAGE); 98.3% (SEC-HPLC)Cor e Forma:LiquidCAY10614
CAS:<p>CAY10614 is a TLR4 antagonist.</p>Fórmula:C42H78INO2Cor e Forma:SolidPeso molecular:755.995Tetrachlorohydroquinone
CAS:<p>TCHQ, a pentachlorophenol metabolite, toxic to trout liver cells, increases ROS, disrupts mitochondria, and causes necrosis in splenocytes. EC50: 1.55 μM.</p>Fórmula:C6H2Cl4O2Cor e Forma:SolidPeso molecular:247.89(R)-Zadavotide guraxetan
CAS:<p>Zadavotide guraxetan (PSMAI&T; PNT-2002) is an inhibitor of prostate-specific membrane antigen (PSMA) with potential antitumor activity, and it is useful for research targeting prostate cancer.</p>Fórmula:C63H92IN11O23Cor e Forma:SolidPeso molecular:1498.37NBD peptide
CAS:<p>NBD peptide inhibits the NF-κB signaling pathway by preventing the binding of the NEMO-IKK complex. It exhibits anti-inflammatory activity by blocking the production of pro-inflammatory cytokines. Additionally, NBD peptide demonstrates immunosuppressive effects through the regulation of immune cells. It enhances transmembrane capacity by conjugating with the cell-penetrating peptide HIV-TAT.</p>Fórmula:C62H88N14O20Cor e Forma:SolidPeso molecular:1349.44Simlukafusp alfa
CAS:<p>Simlukafusp alfa (FAP-IL2v) is a tumor-targeting immune cytokine, a human IgG1 antibody with antitumor activity and immunostimulatory properties.</p>Pureza:97.3% (SDS-PAGE); 94.3% (SEC-HPLC) - 97.3% (SDS-PAGE); 94.3% (SEC-HPLC)Cor e Forma:LiquidPMX 205 Trifluoroacetate
<p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>Fórmula:C47H63F3N10O8Cor e Forma:SolidPeso molecular:953.06C2 Ceramide (d14:1/2:0)
CAS:<p>C2 Ceramide (d14:1/2:0), a bioactive sphingolipid, causes lipotoxic cardiomyopathy when fed to Drosophila at 100 μM.</p>Fórmula:C16H31NO3Cor e Forma:SolidPeso molecular:285.42Phthalazine
CAS:<p>Compound PDK0135, with CAS No. 253-52-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0135 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C8H6N2Cor e Forma:Yellow SolidPeso molecular:130.14AChE-IN-85
<p>AChE-IN-85 (Compound 7k) is an acetylcholinesterase inhibitor with an IC50 of 0.083 μM. It reduces nitric oxide (NO) release, the production of TNF-α and IL-1β, as well as levels of LDH and ROS, and inhibits Aβ42 aggregation. AChE-IN-85 exhibits anti-inflammatory and neuroprotective effects and is applicable for research on diseases such as Alzheimer's.</p>Cor e Forma:Odour SolidKD014
<p>KD014 (DX-2400) is a human monoclonal antibody (mAb) that targets MMP14, with a Ki of 0.9 nM. It inhibits TGFβ and SMAD2/3 signaling, increases macrophage count and iNOS expression, and shifts macrophage phenotype towards an antitumor M1-like type. KD014 exhibits antitumor activity in three tumor models (MDA-MB-231, MDA-MB-435, and PC3) and is applicable in breast cancer research.</p>Cor e Forma:Odour LiquidSTING agonist-17
CAS:<p>STING agonist-17 (compound 4a) is a highly potent stimulator of the STING pathway, exhibiting an IC 50 of 0.062 nM.</p>Fórmula:C43H53N13O8Cor e Forma:SolidPeso molecular:879.96
