Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(148 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(60 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(444 produtos)
- NOD(17 produtos)
- NOS(63 produtos)
- Nrf2(79 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3045 produtos de "Imunologia e Inflamação"
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WK692
CAS:<p>Compound WK692 (compund WK692) is a BCL6 inhibitor that effectively suppresses the growth of diffuse large B-cell lymphoma cells without toxic side effects and acts synergistically with inhibitors of EZH2 and PRMT5.</p>Fórmula:C26H28Br2N8O5Cor e Forma:SolidPeso molecular:692.36mPGES1-IN-5
CAS:<p>mPGES1-IN-5 (compound 18) is a multi-substituted pyrimidine compound that acts as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and demonstrates significant inhibitory activity in vivo against acute inflammation models.</p>Fórmula:C27H27N3OCor e Forma:SolidPeso molecular:409.52AM103
CAS:<p>AM103 is an effective and selective inhibitor of FLAP (IC50 = 4.2 nM).</p>Fórmula:C36H38N3NaO4SPureza:99.75%Cor e Forma:SolidPeso molecular:631.76Zharp1-211
CAS:<p>Zharp1-211 is a RIPK3 inhibitor，reduces JAK/ stat1-mediated chemokines and MHC class II molecules in IECs, (GVHD) for gastrointestinal inflammation.</p>Fórmula:C24H25N5O4Pureza:99.71%Cor e Forma:SolidPeso molecular:447.49Antiproliferative agent-22
CAS:<p>Antiproliferative agent-22 is an anticancer compound that shows antiproliferative activity on MCF-7, MDA-MB-231 and MDA-MB-468 cells.</p>Fórmula:C17H13N3O3Pureza:99.20% - 99.27%Cor e Forma:SolidPeso molecular:307.3Dazostinag disodium
CAS:<p>Dazostinag disodium (TAK-676) is a synthetic novel interferon gene (STING) agonist.Cost-effective and quality-assured.</p>Fórmula:C21H20F2N8Na2O10P2S2Pureza:98.84% - 99.96%Cor e Forma:SolidPeso molecular:754.48VVD-130037
CAS:<p>VVD-130037 is a KEAP1 activator with potential antitumor activity.VVD-130037 inhibits tumor growth in advanced solid tumors by degrading NRF2.</p>Fórmula:C17H17ClN4O2Pureza:99.01% - 99.92%Cor e Forma:SolidPeso molecular:344.8HOIPIN-8 sodium
CAS:<p>HOIPIN-8 sodium is a LUBAC inhibitor for the study of inflammatory and immune diseases.</p>Fórmula:C23H15F2N4NaO3Pureza:97.34%Cor e Forma:SolidPeso molecular:456.38UBS109
CAS:<p>UBS109, a curcumin analog, is a DNA demethylating agent in pancreatic cancer that promotes osteoblast differentiation and mineralization.</p>Fórmula:C18H17N3OPureza:99.48%Cor e Forma:SolidPeso molecular:291.35Evixapodlin
CAS:<p>Evixapodlin (PD-1/PD-L1-IN 7) is a human PD-1/PD-L1 protein/protein interaction inhibitor (IC50: 0.213).Evixapodlin has anticancer and antiviral activities.</p>Fórmula:C34H36Cl2N8O4Pureza:99.07%Cor e Forma:SolidPeso molecular:691.61KI696
CAS:<p>KI696 is a high-affinity probe that potently inhibits the interaction of Keap1 and NRF2.</p>Fórmula:C28H30N4O6SPureza:99.74%Cor e Forma:SolidPeso molecular:550.63Darizmetinib
CAS:<p>Darizmetinib (HRX215) is an MKK4 inhibitor.</p>Fórmula:C21H17F2N5O3SPureza:98.03% - 99.57%Cor e Forma:SolidPeso molecular:457.45NSC23925
CAS:NSC23925 is a selective and effective inhibitor of P-glycoprotein (Pgp).Fórmula:C22H26Cl2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:421.362-Selenouracil
CAS:<p>2-Selenouracil is a specialized photosensitizer for photodynamical therapy.</p>Fórmula:C4H4N2OSeCor e Forma:SolidPeso molecular:175.05Veledimex
CAS:<p>Veledimex is an oral activator ligand for a proprietary gene therapy promoter system. It is also a moderate inhibitor of and substrate for CYP3A4/5.</p>Fórmula:C27H38N2O3Pureza:98%Cor e Forma:SolidPeso molecular:438.6PSB-12379
CAS:<p>PSB-12379 is a potent inhibitor of Ecto-5'-Nucleotidase (CD73)(Kis of 9.03 nM (rat) and 2.21 nM (human)).</p>Fórmula:C18H23N5O9P2Pureza:98%Cor e Forma:SolidPeso molecular:515.359a-Fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione
CAS:Fórmula:C22H29FO5Pureza:99%Cor e Forma:SolidPeso molecular:392.461111β,17α,21-Trihydroxypregn-4-ene-3,20-dione
CAS:Fórmula:C21H30O5Pureza:98%Cor e Forma:SolidPeso molecular:362.4599Ref: IN-DA003AAY
Produto descontinuado11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione
CAS:Fórmula:C21H28O5Pureza:98%Cor e Forma:SolidPeso molecular:360.4440(11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
CAS:Fórmula:C24H31FO6Pureza:99%Cor e Forma:SolidPeso molecular:434.4977Ref: IN-DA0039HQ
Produto descontinuadoα-Terpineol
CAS:<p>Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.</p>Fórmula:C10H18OPureza:97.55%Cor e Forma:Colorless LiquidPeso molecular:154.25Ref: IN-DA0034OW
Produto descontinuadoJH-X-119-01 hydrochloride
CAS:<p>JH-X-119-01 hydrochloride is a potent, selective inhibitor of interleukin-1 receptor-associated kinase 1 (IRAK1) that effectively alleviates lipopolysaccharide (LPS)-induced sepsis in mice.</p>Fórmula:C25H21ClN6O3Cor e Forma:SolidPeso molecular:488.93Pam2CSK4 TFA
<p>Pam2CSK4 TFA (PUL-042 TFA) is a potent dual agonist of TLR2 and TLR6, a peptide that mimics bacterial lipoproteins.Pam2CSK4 TFA promotes platelet aggregation, and can be used to study the effects of lipoproteins on the periodontium.</p>Fórmula:C67H127F3N10O14SPureza:99.90%Cor e Forma:SoildPeso molecular:1385.84gp91ds-tat
<p>gp91ds-tat is a useful organic compound for research related to life sciences and the catalog number is T35393.</p>Pureza:98%Cor e Forma:SolidXibornol
CAS:<p>Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。</p>Fórmula:C18H26OCor e Forma:SolidPeso molecular:258.4Racemic Naproxen
CAS:<p>Racemic Naproxen is a biochemical substance.</p>Fórmula:C14H14O3Pureza:98%Cor e Forma:Crystals From Acetone-Hexane White SolidPeso molecular:230.26RIDR-PI-103
CAS:<p>RIDR-PI-103 is a reactive oxygen species (ROS)-induced drug release prodrug featuring an autocyclized portion connected to the pan-PI3K inhibitor (PI-103). In MDA-MB-361 and MDA-MB-231 cells, Doxorubicin and RIDR-PI-103 exhibited synergistic inhibition of cancer cell proliferation.</p>Fórmula:C27H25N7O4Cor e Forma:SolidPeso molecular:511.53Tripeptide-41
CAS:<p>Tripeptide-41 (CG-Lipoxyn) is a bioactive peptide known for its ability to reduce fat accumulation.</p>Fórmula:C29H30N4O5Pureza:98%Cor e Forma:SolidPeso molecular:514.572,3-Bis(3-indolylmethyl)indole
CAS:<p>2,3-Bis(3-indolylmethyl)indole exhibits a concentration-dependent inhibition of RANKL-induced osteoclastogenesis, actin ring formation, and bone resorption.</p>Fórmula:C26H21N3Cor e Forma:SolidPeso molecular:375.475Elamipretide acetate
<p>Elamipretide acetate (MTP 131), a small tetrapeptide, targets mitochondria to reduce toxic species and stabilize cardiolipin.</p>Fórmula:C34H53N9O7Pureza:99.76%Cor e Forma:SoildPeso molecular:699.84Di-O-methyldemethoxycurcumin
CAS:<p>Di-O-methyldemethoxycurcumin is a Curcumin analog isolated from medicinal plant turmeric di-orthomethyldemethoxycurcumin, anti-inflammatory and antioxidant properties Inhibition of IL-6 production, EC50 is 16.20μg/mL.</p>Fórmula:C22H22O5Pureza:98%Cor e Forma:SolidPeso molecular:366.41STING agonist-22
CAS:<p>STING agonist-22 (CF501) boosts vaccines by activating STING, inducing IFN-I and cytokines, aiding in SARS-CoV-2 research.</p>Fórmula:C40H48N14O6Cor e Forma:SolidPeso molecular:820.9Tacalcitol
CAS:<p>Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium and modulates immunological and inflammatory processes.</p>Fórmula:C27H44O3Pureza:98%Cor e Forma:SolidPeso molecular:416.64Icatolimab
<p>Icatolimab (JS-004) is a humanized antibody targeting BTLA/CD272 for the study of lymphomas and solid tumors.</p>Pureza:98.7% (SDS-PAGE); 95.6% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.6% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.5 kDaRef: TM-T77490
Produto descontinuadoTLQP-21 TFA
<p>TLQP-21 TFA is a VGF-derived peptide, C3aR1 agonist (mouse EC50: 10.3μM; human EC50: 68.8μM), that raises intracellular Ca2+ for nociception research.</p>Pureza:98%Cor e Forma:LiquidTLR7/8/9 antagonist 2
CAS:<p>TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. It inhibits HEK/hTLR7, HEK/hTLR8, and HEK/hTLR9 with IC50s of 0.011 μM, 0.029 μM, and 0.052 μM, respectively. TLR7/8/9 antagonist 2 can be used to study auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis.</p>Fórmula:C23H31N7Pureza:98%Cor e Forma:SoildPeso molecular:405.54Magnesium citrate
CAS:<p>Magnesium citrate is a useful organic compound for research related to life sciences. The catalog number is T64455 and the CAS number is 3344-18-1.</p>Fórmula:C12H10Mg3O14Cor e Forma:SolidPeso molecular:451.113TLQP-21 TFA
<p>TLQP-21 TFA （TLQP-21 Trifluoroacetate） 是一种 VGF 衍生肽，可通过结合后折叠机制激活C3aR1 受体。</p>Pureza:98%Aurothioglucose
CAS:<p>Aurothioglucose is a active-site TrxR1 inhibitor.</p>Fórmula:C6H11AuO5SPureza:98%Cor e Forma:Yellow Crystals SolidPeso molecular:392.18ARGX-112
CAS:<p>Temtokibart is a humanized IgG1 λ2 antibody that specifically targets IL22RA1, and is expressed by cells that are deficient in the glutamine synthetase gene.</p>Cor e Forma:Odour LiquidL-NIO dihydrochloride
CAS:<p>L-NIO dihydrochloride, a potent and non-selective NADPH-dependent nitric oxide synthase (NOS) inhibitor, consistently induces focal ischemic infarct in rats. It exhibits inhibitory constants (Kis) of 1.7, 3.9, and 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) forms, respectively.</p>Fórmula:C7H16ClN3O2Pureza:98%Cor e Forma:SolidPeso molecular:209.67ALPK1-IN-1
CAS:<p>ALPK1-IN-1 (A001) strongly inhibits ALPK1, key for innate immunity & NF-κB signaling via TIFA/TRAF.</p>Fórmula:C25H32N6O2SCor e Forma:SolidPeso molecular:480.63ALPK1-IN-2
CAS:<p>ALPK1-IN-2 is a potent inhibitor of ALPK1 (α-kinase 1) (IC50: 95 nM). ALPK1-IN-2 inhibits NF-κB (IC50: 1.31 μM).</p>Fórmula:C20H18F2N4O2SCor e Forma:SolidPeso molecular:416.44Ref: TM-T62162
Produto descontinuadoALPK1-IN-3
CAS:<p>ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances survival in animal models of sepsis-induced</p>Fórmula:C20H16F2N4OSPureza:98%Cor e Forma:SolidPeso molecular:398.43
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