Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(62 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3055 produtos de "Imunologia e Inflamação"
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cGAMP disodium
CAS:<p>cGAMP disodium, a bacterial CDN, boosts interferon production and activates STING, enhancing immune responses as a sublingual adjuvant.</p>Fórmula:C20H24N10O13P2·2NaCor e Forma:SoildPeso molecular:720.39Ginger extract
CAS:<p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>Cor e Forma:SolidFM101
<p>FM101 is a humanized monoclonal anti-IL6 antibody, suitable for use in asthma-related research.</p>Cor e Forma:Odour LiquidHPK1-IN-58
HPK1-IN-58 is an inhibitor of HPK1 (IC50: 2.6 nM) and SLP76 (IC50: 20 nM). It enhances IL-2 secretion, thereby reversing PGE2-induced immunosuppression. HPK1-IN-58 is applicable for research in antitumor immunity.Fórmula:C26H30N8OCor e Forma:SolidPeso molecular:470.25426Antidesmone
CAS:<p>Antidesmone from Ajuga decumbens inhibits acute lung injury by modulating MAPK and NF-κB.</p>Fórmula:C19H29NO3Pureza:98%Cor e Forma:SolidPeso molecular:319.44Valeriandoid F
CAS:<p>Valeriandoid F, an iridoid, strongly inhibits NO production (IC50: 0.88 μM) and has anti-inflammatory, antiproliferative effects.</p>Fórmula:C23H34O9Cor e Forma:SolidPeso molecular:454.516COX-2/15-LOX-IN-2
<p>COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX.</p>Fórmula:C27H26N6OS2Pureza:98%Cor e Forma:SolidPeso molecular:514.66Phytoene desaturase-IN-1
CAS:<p>Potent PDS inhibitor with Kd of 65.9 μM, induces mRNA reduction and ROS accumulation, useful in agriculture.</p>Fórmula:C18H13ClF3N3O2SCor e Forma:SolidPeso molecular:427.83Feeblin
CAS:<p>Feeblin (IRF5-IN-1) induces protein degradation, inhibits pro-inflammatory pathways, and is used for autoimmune disease research.</p>Fórmula:C27H33N3O2Pureza:99.58% - 99.88%Cor e Forma:SoildPeso molecular:431.57PROTAC STING Degrader-1
CAS:<p>PROTAC STING Degrader-1 (Compound SP23) is a STING-targeted PROTAC degrader exhibiting a DC50 of 3.2 μM and demonstrates anti-inflammatory activity [1].</p>Fórmula:C34H33N7O10Cor e Forma:SolidPeso molecular:699.67TLR8 agonist 8
CAS:<p>TLR8 agonist8 (Compound II-72) is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. It demonstrates stability in both human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist8 exhibits antitumor activity, achieving a tumor growth inhibition (TGI) rate of 89%.</p>Fórmula:C53H63N11O10Cor e Forma:SolidPeso molecular:1014.14STING-IN-6
CAS:<p>STING-IN-6 (compound 50), a potent inhibitor of STING, exhibits a pIC50 value of 8.9, indicating its significant inhibitory capacity.</p>Fórmula:C46H52N12O6Cor e Forma:SolidPeso molecular:868.98NF-κΒ activator 1
CAS:<p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>Fórmula:C16H11FN2O2SPureza:99.58%Cor e Forma:SolidPeso molecular:314.33DDX3-IN-1
CAS:DDX3-IN-1 is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50 of 50 and 36 μM for HIV and HCV, respectively. Antiviral activity.Fórmula:C17H17N5OCor e Forma:SolidPeso molecular:307.35CHBO4
CAS:<p>CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and</p>Fórmula:C15H10BrFOPureza:98.14%Cor e Forma:SolidPeso molecular:305.14PSB-24000
<p>PSB-24000 (Compound 27) is a selective ecto-5'-nucleotidase (CD73) inhibitor with a Ki value of 563 nM for inhibiting human CD73, and a Ki of 481 nM in membrane-bound CD73 in triple-negative breast cancer cells. It disrupts CD73’s recognition and action on substrate AMP, preventing AMP-induced immunosuppressive and pro-cancer adenosine production. PSB-24000 is promising for cancer research.</p>Cor e Forma:Odour Solid3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide
CAS:<p>3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).</p>Fórmula:C28H24ClN3O6Pureza:99.9%Cor e Forma:SolidPeso molecular:533.96Anti-IL11RA Antibody (X209)
<p>Anti-IL11RA Antibody (X209) is a human-derived IgG4, κ type antibody inhibitor targeting human IL-11RA.</p>Cor e Forma:Odour LiquidTimosaponin E2
CAS:Timosaponin E2 is an anti-inflammatory agent that inhibits active oxygen production [1].Fórmula:C46H78O20Cor e Forma:SolidPeso molecular:951.1Photosensitizer-4
Compound PS-I (Photosensitizer-4) is an effective photosensitizer that can efficiently kill cancer cells and inhibit tumor growth under light exposure.Cor e Forma:Odour Solid[12]-Dehydrogingerdione
CAS:<p>[12]-Dehydrogingerdione is a natural product found in ginger that has anti-neuroinflammatory activity.Cost-effective and quality-assured.</p>Fórmula:C23H34O4Pureza:98%Cor e Forma:SolidPeso molecular:374.51Dovanvetmab
CAS:<p>Dovanvetmab (ZTS-00521505) is an IgG1-κ monoclonal antibody that targets feline interleukin 31 (Felcat IL31), primarily produced in Chinese Hamster Ovary (CHO)</p>Cor e Forma:LiquidInflexuside A
CAS:<p>Inflexuside A, an abietane diterpenoid from Isodon inflexus, and Inflexuside B inhibit NO in LPS-stimulated RAW264.7 cells.</p>Fórmula:C26H42O9Cor e Forma:SolidPeso molecular:498.61Aminopicoline
CAS:<p>Compound Fr16695, with CAS No. 695-34-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16695 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C6H8N2Cor e Forma:White To Pale Yellow Solid FlakesPeso molecular:108.14Cyclic-di-GMP disodium
CAS:Cyclic-di-GMP disodium (5GP-5GP disodium) is a STING agonist and a second messenger in bacteria.Cost-effective and quality-assured.Fórmula:C20H22N10Na2O14P2Pureza:98.98% - 99.93%Cor e Forma:SolidPeso molecular:734.381-Hydroxy-ibuprofen
CAS:<p>1-Hydroxy Ibuprofen, a metabolite in P. australis, targets COX-1/COX-2 with IC50s: 13 μM/370 μM.</p>Fórmula:C13H18O3Cor e Forma:SolidPeso molecular:222.2802Balekafusp alfa
CAS:Balekafusp alfa is a human IgG1κ antibody targeting IL-2, known for its antitumor properties.Cor e Forma:LiquidSyzalterin
CAS:<p>Syzalterin is an NO production inhibitor(IC50 of 1.87 μg/mL).</p>Fórmula:C17H14O5Pureza:98%Cor e Forma:SolidPeso molecular:298.29Obinutuzumab
CAS:<p>Obinutuzumab (Obinutuzumab/afutuzumab) GA101) is a glycoengineered Type II CD20 monoclonal antibody in development for non-Hodgkin lymphoma.</p>Pureza:98.00% - 98.9% (SDS-PAGE); 99.4% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:144.6 kDaPSMA-IN-3
<p>PSMA-IN-3 (compound 17) is a novel, high-affinity inhibitor of Prostate-Specific Membrane Antigen (PSMA) with an inhibitory concentration (IC50) of 13 nM,</p>Fórmula:C43H50FN7O15Cor e Forma:SolidPeso molecular:923.89Romilkimab
CAS:<p>Romilkimab (SAR156597) is a chimeric humanized immunoglobulin (Ig) antibody designed to specifically target interleukins 4 and 13 (IL-4 and IL-13) [1].</p>Cor e Forma:LiquidQX-005N
QX 005N is a humanized monoclonal anti-CD124/IL4R/IL-4Rα antibody. It is applicable in research related to asthma.Cor e Forma:Odour LiquidSN50 TFA
<p>SN50 TFA is an inhibitor of NF-κB and attenuates alveolar hypercoagulation and fibrinolysis inhibition. SN50 TFA can be used in studies about ARDS.</p>Fórmula:C129H230N36O29S·XCF3COOHCor e Forma:SolidPeso molecular:2781.5 (free base)Tuparstobart
CAS:<p>Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on</p>Cor e Forma:LiquidEPI-589
CAS:<p>EPI-589, a quinone oxidoreductase inhibitor, may treat ALS; it's safe and tolerable.</p>Fórmula:C14H19NO4Pureza:98%Cor e Forma:SolidPeso molecular:265.31FITC-labeled ODN 1585 sodium
<p>FITC-labeled ODN 1585 (sodium) effectively induces IFN and TNFα production and serves to assess CpG ODN cellular uptake and localization through confocal laser-</p>Cor e Forma:Odour SolidNC318
<p>NC318 is a humanized antibody targeting Siglec-15/CD33L3 for the study of non-small cell lung cancer.</p>Pureza:98.6% (SDS-PAGE); 99% (SEC-HPLC) - 98.6% (SDS-PAGE); 99% (SEC-HPLC)Cor e Forma:Odour LiquidNLRP3-IN-74
<p>NLRP3-IN-74 (Compound 11) is an orally active NLRP3 inhibitor with an IC50 of 2.7 μM. It significantly reduces IL-1β release by approximately 90% without affecting TNFα release. NLRP3-IN-74 is applicable in research on diseases such as atherosclerosis and Parkinson's disease.</p>Cor e Forma:Odour SolidMifamurtide sodium
CAS:<p>Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009.</p>Fórmula:C59H108N6NaO19PPureza:98%Cor e Forma:SolidPeso molecular:1259.48LY2409881
CAS:<p>LY2409881 is a selective IκB kinase β ( IKK2 ) inhibitor with an IC 50 of 30 nM.</p>Fórmula:C24H29ClN6OSCor e Forma:SolidPeso molecular:485.05CFT7455
CAS:<p>CFT7455: orally active anti-cancer drug, targets cereblon E3 ligase (Kd 0.9 nM), degrades IKZF1/Ikaros, IKZF3/Aiolos.</p>Fórmula:C28H27N3O4Pureza:97.93%Cor e Forma:SolidPeso molecular:469.53TLR7 agonist 17
CAS:TLR7 agonist 17 (compound 20) functions as a highly effective TLR7 agonist, exhibiting EC 50 values of 12 nM for hTLR7 and 17 nM for mTLR7. Additionally, this compound has demonstrated anticancer activity [1].Fórmula:C25H37N7O3Cor e Forma:SolidPeso molecular:483.61Pam2CSK4
CAS:<p>TLR2/6 agonist; boosts TNF-α in human cells & mouse B cell growth/activation.</p>Fórmula:C65H126N10O12SPureza:98%Cor e Forma:SolidPeso molecular:1271.83MethADP sodium salt
CAS:<p>MethADP is a specific CD73 inhibitor.</p>Fórmula:C11H17N5NaO9P2Pureza:98%Cor e Forma:SolidPeso molecular:448.22NLRP3-IN-14
CAS:<p>NLRP3-IN-14, potent selective NLRP3 inhibitor, KD 5.87μM; IC50 0.131μM for IL-1β; for inflammation research.</p>Fórmula:C27H28N2O4Cor e Forma:SolidPeso molecular:444.52IKZF-IN-1
<p>IKZF-IN-1 (Compound I) is a molecular glue that degrades the karos zinc finger family proteins (IKZF) IKZF 1/2/3/4 and is used as an immune modulator in cancer and viral infection research.</p>Fórmula:C26H28FN5O4Cor e Forma:SolidPeso molecular:493.533′-Hydroxy-4′-O-methylglabridin
CAS:<p>3′-Hydroxy-4′-O-methylglabridin effectively prevents NADH-dependent peroxidation, exhibiting potent antioxidant properties [1].</p>Fórmula:C21H22O5Cor e Forma:SolidPeso molecular:354.4Keap1-Nrf2-IN-3
CAS:<p>Keap1-Nrf2-IN-3 is a KEAP1:NRF2 protein protein interaction inhibitor, and with a K d value of 2.5 nM for KEAP1 protein.</p>Fórmula:C31H34N6O3Cor e Forma:SolidPeso molecular:538.652CDN-A
CAS:<p>CDN-A, a cyclic di-nucleotide, activates immune response & aids in ADC synthesis.</p>Fórmula:C22H29N11O12P2Cor e Forma:SolidPeso molecular:701.48FM-303
<p>FM-303 is a monoclonal antibody inhibitor that targets interleukin-23 (IL-23). It shows promise for research in immune system and digestive system diseases.</p>Cor e Forma:Odour Liquid
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