Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(63 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3054 produtos de "Imunologia e Inflamação"
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cyclo(RLsKDK) TFA
<p>Cyclo(RLsKDK) TFA (BK-1361 TFA) is a cyclic peptide and selective ADAM8 metalloproteinase inhibitor, used in research on inflammation and cancer.</p>Fórmula:C33H58F3N11O11Pureza:98.54%Cor e Forma:SolidPeso molecular:841.88Human Immunoglobulin M
<p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>Cor e Forma:Odour SolidVemircopan
CAS:<p>Vemircopan is a complement factor D inhibitor.</p>Fórmula:C29H28BrN7O3Cor e Forma:SolidPeso molecular:602.493Dazostinag
CAS:<p>Dazostinag (TAK-676) is a STING agonist with anti-cancer properties, used in making ADCs.</p>Fórmula:C21H22F2N8O10P2S2Cor e Forma:SolidPeso molecular:710.52KD014
<p>KD014 (DX-2400) is a human monoclonal antibody (mAb) that targets MMP14, with a Ki of 0.9 nM. It inhibits TGFβ and SMAD2/3 signaling, increases macrophage count and iNOS expression, and shifts macrophage phenotype towards an antitumor M1-like type. KD014 exhibits antitumor activity in three tumor models (MDA-MB-231, MDA-MB-435, and PC3) and is applicable in breast cancer research.</p>Cor e Forma:Odour LiquidDihydromyristicin
CAS:<p>Dihydromyristicin, a plant flavonoid, curbs inflammation by inhibiting ROS and PI3K/Akt/NF-κB pathways.</p>Fórmula:C11H14O3Cor e Forma:SolidPeso molecular:194.23Torudokimab
<p>Torudokimab (ZB-880) is a monoclonal antibody that neutralizes interleukin 33 and can be used to study immune system diseases.</p>Pureza:95.8% (SDS-PAGE); 96.2% (SEC-HPLC) - 95.8% (SDS-PAGE); 96.2% (SEC-HPLC)Cor e Forma:Odour LiquidChitoheptaose heptahydrochloride
CAS:<p>Chitoheptaose heptahydrochloride, a chitosan derivative, enhances wheat growth and photosynthesis, with health-protective traits.</p>Fórmula:C42H80ClN7O29Cor e Forma:SolidPeso molecular:1182.57DZ-837
<p>DZ-837 is a PROTAC that targets the BCL6 protein. The composition of DZ-837 includes the BCL6 ligand-2, the E3 ubiquitin ligase ligand Thalidomide-4-OH, and a PROTAC Linker. The configuration notably features a conjugate of the E3 ubiquitin ligase ligand and the Linker, designated as 2-(2,6-Dioxopiperidin-3-yl)-4-((2-(2-hydroxyethoxy)ethyl)amino)isoindoline-1,3-dione.</p>Fórmula:C42H44FN9O7SCor e Forma:SolidPeso molecular:837.92PSMA-DA1
CAS:PSMA–DA1 may be a useful PSMA-targeting radiotheranostic agent.Fórmula:C50H76IN9O20Cor e Forma:SolidPeso molecular:1250.1054-ACETAMIDOANTIPYRINE
CAS:<p>4-ACETAMIDOANTIPYRINE, with CAS No. 83-15-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-ACETAMIDOANTIPYRINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C13H15N3O2Cor e Forma:SolidPeso molecular:245.28Bectumomab
CAS:<p>Bectumomab (IMMU-LL2) is a humanized IgG2a mAb targeting CD22, used in imaging and staging non-Hodgkin's lymphoma.</p>Cor e Forma:LiquidAM-103 Free Acid
CAS:<p>AM-103 Free Acid is a bio-active chemical.</p>Fórmula:C36H39N3O4SCor e Forma:SolidPeso molecular:609.78PU23
CAS:<p>PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).</p>Fórmula:C21H19N3O3S2Pureza:99.52%Cor e Forma:SolidPeso molecular:425.52Spirohexenolide A
CAS:<p>Spirohexenolide A is an inhibitor of human macrophage migration inhibitory factor (hMIF) with a dissociation constant (Kd) of 35.9 μM. It is employed in the study of cellular transport.</p>Cor e Forma:Solid6Lac[6]Met
CAS:<p>6Lac[6]Met is a galectin-4 inhibitor with an IC50 value of 5 μM [1].</p>Fórmula:C126H180N12O66S6Cor e Forma:SolidPeso molecular:3111.21Antitumor agent-185
<p>Antitumor agent-185 (compound 3) exhibits significant antitumor effects, effectively inhibiting tumor growth and extending the survival period of mice in vivo.</p>Fórmula:C109H199N5O36P2Cor e Forma:SolidPeso molecular:2217.71Y13g dihydrochloride
<p>Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are</p>Fórmula:C16H25ClN2O4Pureza:97.81%Cor e Forma:SoildPeso molecular:344.83PROTAC IRAK4 degrader-4
CAS:<p>PROTAC IRAK4 degrader-4 is a targeted Cereblon-based molecule for degrading IRAK4.</p>Fórmula:C41H38F3N11O10Cor e Forma:SolidPeso molecular:901.817OATD-02 hydrochloride
<p>OATD-02 hydrochloride is the hydrochloride salt form of OATD-02. It is an orally effective, competitive, reversible, and non-covalent dual inhibitor of Arginase1 and Arginase2. OATD-02 hydrochloride serves as a sustained-release inhibitor that efficiently blocks the activity of intracellular arginases, with IC50 values of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1). It effectively eliminates tumor-induced immunosuppression caused by both types of arginases. This compound is utilized in research studies on melanoma.</p>Cor e Forma:Odour SolidPSMA-IN-2
CAS:<p>PSMA-IN-2, an inhibitor of PSMA with a K i value of 1.07 nM, exhibits favorable in vivo NIR imaging (λ EM = 1088 nm, λ ex = 808 nm) and is useful for NIRII image-guided tumor resection surgery in PSMA-positive tumor-bearing mice [1].</p>Fórmula:C54H60N14O18S2Cor e Forma:SolidPeso molecular:1257.27Mifamurtide
CAS:<p>Mifamurtide is a drug against osteosarcoma, is an immunomodulator with antitumor effects.</p>Fórmula:C59H109N6O19PPureza:98%Cor e Forma:SolidPeso molecular:1237.5VEN-02XX
<p>VEN-02XX is an orally active NLRP3 inhibitor capable of penetrating the brain. It effectively suppresses the release of IL-1β and IL-18, with IC50 values of 0.3 and 0.28 μM, respectively. In the 5XFAD/Rubicon KO mouse model, VEN-02XX aids in restoring memory and cognition, inhibits microgliosis, and alleviates neuroinflammation and tau protein pathology. This compound is valuable for Alzheimer's disease (AD) research.</p>Fórmula:C18H16ClF3N4OCor e Forma:SolidPeso molecular:396.79Mipeginterferon alfa-2b
CAS:<p>Mipeginterferon alfa-2b, an IFNA2b analogue, has 5 modified amino groups out of 11 and weighs 40 kDa.</p>Cor e Forma:LiquidDectrekumab
CAS:<p>Dectrekumab (QAX576) is a humanized monoclonal antibody targeting IL-13.</p>Pureza:96.5% (SDS-PAGE); 97.1% (SEC-HPLC) - 96.5% (SDS-PAGE); 97.1% (SEC-HPLC)Cor e Forma:LiquidBavunalimab
CAS:<p>Bavunalimab: bispecific anti-CTLA-4/LAG-3 antibody, T-cell activator in NSG mice, for cancer research.</p>Cor e Forma:LiquidNC318
<p>NC318 is a humanized antibody targeting Siglec-15/CD33L3 for the study of non-small cell lung cancer.</p>Pureza:98.6% (SDS-PAGE); 99% (SEC-HPLC) - 98.6% (SDS-PAGE); 99% (SEC-HPLC)Cor e Forma:Odour LiquidCDD-3290
<p>CDD-3290 (Compound 20) is an inhibitor of prostate-specific antigen (PSA) with a Ki value of 216 nM. This compound also exhibits inhibitory effects on α-chymotrypsin and elastase.</p>Cor e Forma:Odour SolidFITC-labeled ODN 1826 sodium
<p>FITC-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and</p>Cor e Forma:Odour SolidZ-VRPR-FMK TFA
<p>Z-VRPR-FMK (TFA), a tetrapeptide, irreversibly inhibits MALT1, protecting against influenza A.</p>Fórmula:C33H50F4N10O8Cor e Forma:SolidPeso molecular:790.81Anticonvulsant agent 10
<p>Anticonvulsant agent 10 (Compound 6d) is an inhibitor targeting the Keap1-Nrf2 interaction, with a strong activity showing an ED50 of 0.04 mmol/kg. By inhibiting the Keap1-Nrf2 binding, it activates the Nrf2/ARE pathway, providing anticonvulsant and neuroprotective effects, making it useful for research in epilepsy and neuroprotection.</p>Cor e Forma:Odour SolidBMX-010
CAS:<p>BMX-010, also known as AEOL-10113, is Porphyrin-Based SOD Mimic.</p>Fórmula:C48H44Cl5MnN8Cor e Forma:SolidPeso molecular:965.12CDN-A
CAS:<p>CDN-A, a cyclic di-nucleotide, activates immune response & aids in ADC synthesis.</p>Fórmula:C22H29N11O12P2Cor e Forma:SolidPeso molecular:701.48PROTAC IRAK4 degrader-5
CAS:<p>PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.</p>Fórmula:C41H40F3N11O9Cor e Forma:SolidPeso molecular:887.834Zuberitamab
CAS:<p>Zuberitamab (HS006) is a monoclonal antibody targeting CD20, utilized in cancer research, notably in diffuse large B-cell lymphoma [1].</p>Cor e Forma:LiquidEC1169
CAS:<p>EC1169 is a targeted PSMA ligand that acts to inhibit the proliferation of cells expressing PSMA.</p>Fórmula:C78H112N14O28S3Cor e Forma:SolidPeso molecular:1790.00CNTO 607
<p>CNTO 607 (Anti-IL-13 Antibody) is a humanized antibody targeting IL-13, useful for studying inflammation.</p>Pureza:98% (SDS-PAGE); 98.3% (SEC-HPLC) - 98% (SDS-PAGE); 98.3% (SEC-HPLC)Cor e Forma:Odour LiquidNLRP3-IN-12
<p>NLRP3-IN-12 inhibits NLRP3 inflammasome, curbing IL-1β release with 0.45 μM IC50, for inflammatory bowel disease research.</p>Fórmula:C27H32ClNO7Cor e Forma:SolidPeso molecular:518TLR7/8 agonist 4 TFA
CAS:<p>TLR7/8 agonist 4 TFA (compound 41) is a highly potent TLR7/8 agonist that exhibits significant anti-cancer activity.</p>Fórmula:C20H25F3N6O2Cor e Forma:SolidPeso molecular:438.45Eritoran Tetrasodium
CAS:<p>Eritoran Tetrasodium, a TLR4 receptor antagonist, is used potentially for the treatment of type 2 diabetes.</p>Fórmula:C66H122N2Na4O19P2Pureza:98%Cor e Forma:SolidPeso molecular:1401.58Keap1/Nrf2/ARE activator 1
<p>Keap1/Nrf2/ARE activator 1 (compound HT-3) functions as an activator of the Keap1/Nrf2/ARE pathway. This compound has antioxidant properties and offers neuroprotective effects.</p>Fórmula:C19H20O6Cor e Forma:SolidPeso molecular:344.12599IKKγ NBD Inhibitory Peptide
CAS:<p>A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF</p>Fórmula:C170H259N49O42S1Pureza:98%Cor e Forma:SolidPeso molecular:3693.3Lonazolac Calcium
CAS:<p>Lonazolac Calcium, a nonsteroidal anti-inflammatory drug (NSAID), is used to treat inflammation and pain.</p>Fórmula:C34H24CaCl2N4O4Pureza:98%Cor e Forma:SolidPeso molecular:663.56PMX 205 Trifluoroacetate
<p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>Fórmula:C47H63F3N10O8Cor e Forma:SolidPeso molecular:953.06TP508
CAS:<p>TP508 (Chrysalin), a 23-amino-acid peptide from human prothrombin, aids in tissue repair, targeting thrombin receptors.</p>Fórmula:C97H146N28O36SPureza:98%Cor e Forma:SolidPeso molecular:2312.44DOPAL
CAS:<p>DOPAL, a neurotoxic aldehyde from dopamine metabolism, is linked to Parkinson's and can convert to DOPAC or DOPET.</p>Fórmula:C8H8O3Cor e Forma:SolidPeso molecular:152.15FITC-labeled Agatolimod sodium
<p>FITC-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and</p>Cor e Forma:Odour SolidMAPK-IN-4
<p>MAPK-IN-4 (Compound c1) is an orally active anti-inflammatory agent that inhibits the expression and release of pro-inflammatory cytokines IL-6 and TNF-α induced by LPS. It interacts with IRAK4 to exert its anti-inflammatory effects by inhibiting the MAPK pathway.</p>Cor e Forma:Odour SolidROS inducer 6
<p>ROS inducer 6 (compound 9) acts as a reactive oxygen species (ROS) inducer by depleting intracellular glutathione, thereby functioning as an antitumor agent.</p>Fórmula:C32H26N2O3Cor e Forma:SolidPeso molecular:486.56Anti-MRC2/CD280 Antibody
<p>Anti-MRC2/CD280 Antibody is a humanized anti-MRC2/CD280 antibody that can be used in immunoblotting (WB) and immunohistochemistry experiments.</p>Pureza:99.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 99.1% (SDS-PAGE); 98.7% (SEC-HPLC)Cor e Forma:Odour Liquid
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