Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(140 produtos)
- CXCR(153 produtos)
- Parede celular(5 produtos)
- Receptor IL(109 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(25 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(446 produtos)
- NOD(17 produtos)
- NOS(62 produtos)
- Nrf2(82 produtos)
- PGE Sintase(31 produtos)
- ROS(70 produtos)
- TGF-beta/Smad(59 produtos)
- TLR(76 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3304 produtos de "Imunologia e Inflamação"
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Parecoxib
CAS:Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.Fórmula:C19H18N2O4SPureza:99.71% - 99.78%Cor e Forma:SolidPeso molecular:370.42(E/Z)-IT-603
CAS:<p>(E/Z)-IT-603 is a cell-permeable c-Rel inhibitor. IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding activity.</p>Fórmula:C11H9BrN2O3SPureza:99.35%Cor e Forma:SolidPeso molecular:329.17WITHAFERIN A
CAS:WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/Fórmula:C28H38O6Pureza:97.41% - 99.99%Cor e Forma:SolidPeso molecular:470.60DMNQ
CAS:DMNQ: a 1,4-naphthoquinone that boosts intracellular superoxide & H2O2 by redox-cycling, raising ROS levels.Fórmula:C12H10O4Pureza:99.12% - 99.42%Cor e Forma:SolidPeso molecular:218.21DUPA
CAS:DUPA (N,N''-Carbonylbis[L-glutamic acid]) is used as the targeting moiety to actively deliver DTX for treatment of Prostate-Specific Membrane Antigen (PSMA)Fórmula:C11H16N2O9Pureza:99.56%Cor e Forma:SolidPeso molecular:320.25Ustekinumab
CAS:Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.Pureza:98% - 99.70%Cor e Forma:LiquidPeso molecular:148 kDaStemRegenin 1
CAS:StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor.Fórmula:C24H23N5OSPureza:98% - 99.89%Cor e Forma:SolidPeso molecular:429.548-Deoxygartanin
CAS:8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it hasFórmula:C23H24O5Pureza:99.04% - 99.88%Cor e Forma:SolidPeso molecular:380.43N-acetylcysteine amide
CAS:<p>N-Acetylcysteine amide is a thiol antioxidant and a neuroprotective agent with cell permeability and blood-brain barrier permeability. Cost-effective and quality-assured.</p>Fórmula:C5H10N2O2SPureza:99.36% - ≥98%Cor e Forma:SolidPeso molecular:162.21Mbx2329
CAS:<p>MBX2329 is a specific inhibitor of HA-mediated viral entry that inhibits H1N1 virus strain high pathogenic avian influenza H5N1 virus strain.</p>Fórmula:C16H26ClNOPureza:99.82%Cor e Forma:SolidPeso molecular:283.84BAY-218
CAS:Bindarit (AF2838) is an aryl hydrocarbon receptor (AHR) antagonist.Cost-effective and quality-assured.Fórmula:C20H17ClFN3O3Pureza:99.46% - 99.85%Cor e Forma:SolidPeso molecular:401.82Ceefourin 1
CAS:<p>Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.</p>Fórmula:C11H10N4S3Pureza:99.15%Cor e Forma:SolidPeso molecular:294.42IRAK inhibitor 6
CAS:<p>IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).</p>Fórmula:C20H20N4O3SPureza:99.44%Cor e Forma:SolidPeso molecular:396.46Lumiracoxib
CAS:<p>Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.</p>Fórmula:C15H13ClFNO2Pureza:96.64% - 99.77%Cor e Forma:Pale Yellow SolidPeso molecular:293.72EC330
CAS:EC330, a novel steroidal LIF inhibitor showed cytotoxicity in various cancer cell lines and NCI-60 cell line panel at low nano-molar range.Fórmula:C30H32F2O2Pureza:97.83%Cor e Forma:SolidPeso molecular:462.57Necrostatin-34
CAS:<p>Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a</p>Fórmula:C18H16N4O2S2Pureza:98.66% - 98.8%Cor e Forma:SolidPeso molecular:384.48GLX351322
CAS:GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.Fórmula:C21H25N3O5SPureza:99.93%Cor e Forma:SolidPeso molecular:431.51Losartan Carboxaldehyde
CAS:Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.Fórmula:C22H21ClN6OPureza:99.1%Cor e Forma:SolidPeso molecular:420.89Carbidopa monohydrate
CAS:<p>Carbidopa monohydrate (S(-)-Carbidopa) is an inhibitor of DOPA decarboxylase, preventing the conversion of levodopa to dopamine.</p>Fórmula:C10H16N2O5Pureza:98.11% - 98.30%Cor e Forma:SolidPeso molecular:244.24Zingerone
CAS:<p>Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale with potent anti-inflammatory, antidiabetic and anti-tumor properties.</p>Fórmula:C11H14O3Pureza:99.38% - 99.85%Cor e Forma:Clear Slightly Yellow LiquidPeso molecular:194.23CP 424174
CAS:CP 424174 blocks IL-1β processing (IC50: 210 nM), halts mature IL-1β formation, limits NLRP3, and is effective orally in vivo.Fórmula:C22H29ClN2O4SPureza:>99.99%Cor e Forma:SolidPeso molecular:452.99Enoxaparin sodium
CAS:Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.Fórmula:C42H59N3Na4O35S2Pureza:98%Cor e Forma:SolidPeso molecular:1322Sulfuretin
CAS:<p>Sulfuretin protects HepG2 cells from oxidative damage by scavenging ROS and activating HO-1 via Nrf2/ARE and JNK/ERK pathways.</p>Fórmula:C15H10O5Pureza:98.91% - 99.86%Cor e Forma:SolidPeso molecular:270.24Forsythoside B
CAS:Forsythoside B inhibits LPS, NF-κB, inflammation, offers neuroprotection, reduces ischemia injury, and has antioxidant and antisepsis effects.Fórmula:C34H44O19Pureza:98% - 99.81%Cor e Forma:SolidPeso molecular:756.70Esculentoside A
CAS:Esculentoside A dampens inflammation in ALI, modulates T cells, and could treat autoimmune diseases and BXSB mice by adjusting cytokines and renal cells.Fórmula:C42H66O16Pureza:98% - 99.85%Cor e Forma:SolidPeso molecular:826.96MCC950 sodium
CAS:<p>MCC950 sodium (CP-456773 sodium) is a potent and selective inhibitor of the inflammatory vesicle NLRP3 (IC50=7.5 nM in BMDMs; IC50=8.1 nM in HMDMs).</p>Fórmula:C20H23N2O5S·NaPureza:95.49% - 99.80%Cor e Forma:SolidPeso molecular:426.46Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Fórmula:C20H18O11Pureza:97.02% - 99.94%Cor e Forma:White PowderPeso molecular:434.35TAK-243
CAS:TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM).Fórmula:C19H20F3N5O5S2Pureza:98.09% - 98.93%Cor e Forma:SolidPeso molecular:519.52α-MSH
CAS:α-MSH (MSH, amide) is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.Fórmula:C77H109N21O19SPureza:99.10% - 99.67%Cor e Forma:White PowderPeso molecular:1664.89ML324
CAS:ML324(IC50=920 nM) is a specific inhibitor of jumonji histone demethylase (JMJD2).Fórmula:C21H23N3O2Pureza:98.22% - 98.57%Cor e Forma:SolidPeso molecular:349.43Fas C-Terminal Tripeptide Acetate
Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding.Fórmula:C18H33N3O8Pureza:99.12%Cor e Forma:SolidPeso molecular:419.47Glu-urea-Lys TFA(1025796-69-3 free base)
<p>Glu-urea-Lys TFA (1025796-69-3 free base) is a PSMA inhibitor.</p>Fórmula:C14H22F3N3O9Pureza:99.91%Cor e Forma:SolidPeso molecular:433.34NF-κB-IN-1
CAS:NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathwayFórmula:C31H30O8Pureza:99.03%Cor e Forma:SolidPeso molecular:530.57STING agonist-1
CAS:STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.Fórmula:C21H16ClFN2O3SPureza:99.07%Cor e Forma:SolidPeso molecular:430.88Caffeic Acid Phenethyl Ester
CAS:CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.Fórmula:C17H16O4Pureza:99.18% - 99.35%Cor e Forma:Less Transparent Liquid Colorless Transparent LiquidPeso molecular:284.31Bay 11-7085
CAS:<p>Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).</p>Fórmula:C13H15NO2SPureza:99.76% - 99.94%Cor e Forma:White SolidPeso molecular:249.33FR 122047
CAS:FR 122047 (1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride) is a potent and selective inhibitor of COX-1 with IC50 of 28 nMFórmula:C23H26ClN3O3SPureza:99.93%Cor e Forma:SolidPeso molecular:459.99Mavacoxib
CAS:Mavacoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) ,with Anti-Tumour activity.Fórmula:C16H11F4N3O2SPureza:99.90%Cor e Forma:SolidPeso molecular:385.34Betulinic acid
CAS:Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.Fórmula:C30H48O3Pureza:98.22% - 99.7%Cor e Forma:White Crystalline PowderPeso molecular:456.70GOT1 inhibitor-1
CAS:GOT1 inhibitor-1 (GOT1 inhibitor 2c) is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.Fórmula:C19H19ClN4OPureza:99.70%Cor e Forma:SolidPeso molecular:354.83Colistin methanesulfonate sodium salt
CAS:<p>Colistin methanesulfonate sodium salt (Colistimethate Sodium) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.</p>Fórmula:C58H104N16Na5O28S5Pureza:98% - ≥98%Cor e Forma:SolidPeso molecular:1742(Average)HA 155
CAS:HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.Fórmula:C24H19BFNO5SPureza:99.88%Cor e Forma:SolidPeso molecular:463.29E6446
CAS:E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling.Fórmula:C27H35N3O3Pureza:98.72%Cor e Forma:SolidPeso molecular:449.59Complement factor D-IN-2
CAS:Complement factor D-IN-2 is an inhibitor of Complement factor D and reduces the excessive activation of complement factor D.Fórmula:C27H24BrN7O3Pureza:99.53%Cor e Forma:SolidPeso molecular:574.43CBL0137 hydrochloride
CAS:<p>CBL0137 hydrochloride (Curaxin-137 hydrochloride) is an inhibitor of the histone chaperone FACT, which also activates p53 and inhibits NF-κB.Cost-effective and quality-assured.</p>Fórmula:C21H25ClN2O2Pureza:99.35% - 99.86%Cor e Forma:SolidPeso molecular:372.88CH-223191
CAS:CH-223191, a specific aryl hydrocarbon receptor (AhR) antagonist, inhibited TCDD-induced luciferase activity with an IC50 of 0.03 μM. High-Quality, Low-Cost!Fórmula:C19H19N5OPureza:99.01% - 99.71%Cor e Forma:SolidPeso molecular:333.39Zaltoprofen
CAS:Zaltoprofen (Soleton) is a Cox-1 and Cox-2 inhibitor, which is used for the treatment of arthritis.Fórmula:C17H14O3SPureza:99.72%Cor e Forma:Off-White To Pale Yellow Crystalline SolidPeso molecular:298.36AT-56
CAS:AT56, a specific inhibitor of prostaglandin D2 synthase enzymatic activity, blunted adipogenic aldosterone effects.Fórmula:C25H27N5Pureza:98.16% - 99.5%Cor e Forma:SolidPeso molecular:397.52Zomepirac free acid
CAS:Zomepirac is a prostaglandin synthetase inhibitor. Zomepirac is an orally effective nonsteroidal anti-inflammatory drug (NSAID) that has antipyretic actions.Fórmula:C15H14ClNO3Cor e Forma:SolidPeso molecular:291.73Rucaparib monocamsylate
CAS:<p>Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.</p>Fórmula:C29H34FN3O5SPureza:99.82%Cor e Forma:SolidPeso molecular:555.66
