Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(140 produtos)
- CXCR(153 produtos)
- Parede celular(5 produtos)
- Receptor IL(108 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(24 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(445 produtos)
- NOD(17 produtos)
- NOS(62 produtos)
- Nrf2(82 produtos)
- PGE Sintase(31 produtos)
- ROS(70 produtos)
- TGF-beta/Smad(59 produtos)
- TLR(74 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3269 produtos de "Imunologia e Inflamação"
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BMS-509744
CAS:BMS-509744 is a selective, ATP-competitive Itk inhibitor, IC50 of 19 nM. It inhibits IL-8 expression and HIV infection, ameliorates pulmonary inflammation.Fórmula:C32H41N5O4S2Pureza:99.70%Cor e Forma:SolidPeso molecular:623.83Tilarginine
CAS:Tilarginine is a nitric oxide synthetase competitive inhibitor.Fórmula:C7H16N4O2Pureza:98%Cor e Forma:SolidPeso molecular:188.23AP-1/NF-κB activation inhibitor 1
CAS:<p>AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basal</p>Fórmula:C13H11F3N4O4Pureza:99.52% - 99.91%Cor e Forma:SolidPeso molecular:344.25Emlenoflast sodium
CAS:Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome,Fórmula:C19H24N4NaO3SCor e Forma:SolidPeso molecular:411.47Tilarginine citrate
CAS:Tilarginine citrate is a competitive nitric oxide synthetase inhibitor.Fórmula:C13H24N4O9Pureza:98%Cor e Forma:SolidPeso molecular:380.354MIP-1072
CAS:MIP-1072 is the prostate-specific membrane antigen inhibitor.Fórmula:C19H26IN3O7Pureza:98%Cor e Forma:SolidPeso molecular:535.33Nrf2 activator-3
CAS:Nrf2 activator-3 is an Nrf2 activator with potential anti-inflammatory, antioxidant and anti-tumor activity for the study of neurological diseases.Fórmula:C23H18F3N3O2Pureza:98.52% - 99.84%Cor e Forma:SolidPeso molecular:425.4RWJ 63556
CAS:RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.Fórmula:C11H10FNO3S2Pureza:99.92%Cor e Forma:SolidPeso molecular:287.33GSK223
CAS:GSK223 is an iE-DAP-stimulated IL-8 release inhibitor via the NOD1 signaling pathway.Fórmula:C21H18FN3O3S2Pureza:98%Cor e Forma:SolidPeso molecular:443.51NCX1022
CAS:NCX1022 is a NO-releasing derivative of Hydrocortisone. It is the most widely used anti-inflammatory drug for the treatment of skin inflammation.Fórmula:C29H35NO9Pureza:98%Cor e Forma:SolidPeso molecular:541.59LC-R 505
CAS:LC-R 505 is an anti-inflammatory.Fórmula:C20H26N2O5SCor e Forma:SolidPeso molecular:406.5AHR antagonist 5
CAS:Potent, oral AHR blocker from WO2018195397; IC50 < 0.5μM; hinders tumor growth with anti-PD-1.Fórmula:C25H27Cl3FN7Pureza:98%Cor e Forma:SolidPeso molecular:550.89FR20
CAS:FR20 is a human microsomal prostaglandin synthase 1 (mPGES 1) inhibitor.Fórmula:C31H25Cl2N3O2Cor e Forma:SolidPeso molecular:542.46Edasalonexent
CAS:Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.Fórmula:C31H42N2O3Pureza:99.13% - >99.99%Cor e Forma:SolidPeso molecular:490.68NLRP3 antagonist 1
CAS:Potential cancer research drug, NLRP3 antagonist 1, targets immune response in macrophages, neutrophils.Fórmula:C16H18N6OCor e Forma:SolidPeso molecular:310.35Phortress
CAS:<p>Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor</p>Fórmula:C20H25Cl2FN4OSPureza:99.89%Cor e Forma:SolidPeso molecular:459.41Anisodine hydrobromide
CAS:<p>Anisodine hydrobromide is an inhibitor of adenosine kinase.</p>Fórmula:C17H22BrNO5Cor e Forma:White Crystals Or Crystalline PowderPeso molecular:400.27Oxyfenamate
CAS:Oxyfenamate has anti-anxiety actions. It is also used in anxiety neuroses.Fórmula:C11H15NO3Pureza:98%Cor e Forma:SolidPeso molecular:209.24L 748780
CAS:<p>L 748780 is a selective inducible COX-2 inhibitor.</p>Fórmula:C19H14Cl3NO4Pureza:98%Cor e Forma:SolidPeso molecular:426.68StA-IFN-1
CAS:StA-IFN-1 inhibits IFN induction (IC50=4.1 μM), akin to TPCA-1, not IFN signaling like ruxolitinib, and selectively reduces IFN-β mRNA levels.Fórmula:C14H13N3O2Cor e Forma:SolidPeso molecular:255.27QD-394
CAS:<p>QD-394 promotes ROS, impairs GSH/GSSG ratio, and is cytotoxic to pancreatic cancer cells, with synergy with napabucasin.</p>Fórmula:C19H19N5O2Cor e Forma:SolidPeso molecular:349.39COX-2-IN-16
CAS:<p>COX-2-IN-16: potent, selective oral COX-2 blocker, IC50=102 μM, reduces NO, anti-inflammatory.</p>Fórmula:C19H12BrN3O2Cor e Forma:SolidPeso molecular:394.22(R,1R)-Tenofovir amibufenamide
CAS:<p>(R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) can be used as a Tenofovir prodrug, which can be taken orally and has antiviral activity.</p>Fórmula:C22H31N6O5PPureza:98.79% - 99.02%Cor e Forma:SolidPeso molecular:490.49Tiazotic acid
CAS:Tiazotic acid is an agent with the activity of antioxidant.Fórmula:C5H7N3O2SPureza:98%Cor e Forma:SolidPeso molecular:173.19ZXX2-77
CAS:ZXX2-77 is a cyclooxygenase-1 inhibitor.Fórmula:C13H13ClN2O2SPureza:98%Cor e Forma:SolidPeso molecular:296.77NCX-6560
CAS:NCX-6560 is a novel NO-releasing derivative of atorvastatin, with those of atorvastatin.Fórmula:C37H42FN3O8Cor e Forma:SolidPeso molecular:675.74CAY10575
CAS:CAY10575 (IKK2-IN-3) is a potent IKK2 inhibitor with potential anti-inflammatory activity for the study of inflammatory and endocrine diseases.Fórmula:C22H21N3O6S2Cor e Forma:SolidPeso molecular:487.55MIF-IN-5
CAS:MIF-IN-5: reversible MIF inhibitor, IC50 4.8 μM, Ki 3.3 μM.Fórmula:C18H14FN5O2Cor e Forma:SolidPeso molecular:351.33(+)-DHMEQ
CAS:(+)-DHMEQ is an antioxidant transcription factor Nrf2 activator. (+)-DHMEQ is the enantiomer of (-)-DHMEQ.Fórmula:C13H11NO5Cor e Forma:SolidPeso molecular:261.23COX-2-IN-26
CAS:COX-2-IN-26: Oral, selective COX-2 inhibitor, low IC50s; anti-inflammatory with GI safety.Fórmula:C23H21N7OS3Cor e Forma:SolidPeso molecular:507.65AZD5718
CAS:AZD5718: potent FLAP inhibitor (IC50=2.0 nM), treats Coronary Artery Disease, >90% leukotriene suppression, safe in animal studies, in phase 2a trial.Fórmula:C29H34N6O4Cor e Forma:SolidPeso molecular:530.62Fagaramide
CAS:Fagaramide possesses Antiplasmodial activity.Fórmula:C14H17NO3Pureza:98%Cor e Forma:SolidPeso molecular:247.29HSR1304
CAS:<p>HSR1304 (5d) inhibits NFκB, key in diseases like cancer, offering research potential.</p>Fórmula:C24H21ClN2O3Cor e Forma:SolidPeso molecular:420.89Enflicoxib
CAS:Enflicoxib is an effective treatment for canine osteoarthritis pain and inflammation, with faster onset than mavacoxib, improving veterinary outcomes.Fórmula:C16H12F5N3O2SPureza:99.88%Cor e Forma:SolidPeso molecular:405.34LY 150310
CAS:LY 150310, a histamine H1-receptor antagonist, can alter prostanoid concentrations in vitro and in vivo.Fórmula:C13H14N2Cor e Forma:SolidPeso molecular:198.26STING Agonist 1a
CAS:<p>STING agonist 1a activates STING, induces IRF-SEAP, IFN-β, IL-6, CXCL10 (EC50=16.77 µM); effects reversed by STING KO/inhibitor H-151.</p>Fórmula:C19H11Cl2N5OCor e Forma:SolidPeso molecular:396.23L 669083
CAS:L 669083 is two classes of potent leukotriene biosynthesis inhibitors photoaffinity analogue.Fórmula:C29H29IN4O5SPureza:98%Cor e Forma:SolidPeso molecular:672.54NIC-0102
CAS:<p>NIC-0102 is an orally active proteasome inhibitor (pIC50:7.55) that exhibits specific inhibition of NLRP3 inflammatory vesicle activation. Inhibitory effect.</p>Fórmula:C21H25BF2N2O4Cor e Forma:SolidPeso molecular:418.24PD 127443
CAS:PD 127443 is a Leukotriene B4 antagonist, it is also a dual inhibitor of cyclooxygenase and 5-lipoxygenase.Fórmula:C20H28N2OCor e Forma:SolidPeso molecular:312.45TYT-1
CAS:TYT-1 is a West Nile virus (WNV) inhibitor, antiviral (IC₅₀ = 0.7 mM) by blocking the pre-assembly replication step following viral entry into cells.Fórmula:C21H17N3O2S3Pureza:98.49%Cor e Forma:SolidPeso molecular:439.57IRAK4-IN-22
CAS:IRAK4-IN-22: oral IRAK4 inhibitor, IC50: IRAK4-3nM, TAK1-17nM, disrupts IL-23, targets autoimmune diseases.Fórmula:C28H28FN7O2Cor e Forma:SolidPeso molecular:513.57IL-17A modulator-3
CAS:<p>IL-17A modulator-3 inhibits IL-17A/A, IC50 <10 μM, for inflammation, cancer, autoimmune research.</p>Fórmula:C34H50FN7O4Cor e Forma:SolidPeso molecular:639.8TLR7/8 agonist 4
CAS:TLR7/8 agonist 4 (compound 41) is a potent agonist of TLR7/8 with anti-cancer activity [1].Fórmula:C18H24N6Cor e Forma:SolidPeso molecular:324.42CHD-5
CAS:CHD-5 is a selective antagonist of the aryl hydrocarbon receptor (AhR).Fórmula:C19H17N3O2Cor e Forma:SolidPeso molecular:319.36PHA-408
CAS:<p>PHA-408 is a novel potent, highly selective and ATP-competitive inhibitor of IKB kinase-2.</p>Fórmula:C29H27ClFN7O2Pureza:98%Cor e Forma:SolidPeso molecular:560.02NLRP3-IN-16
CAS:NLRP3-IN-16: potent NLRP3 inflammasome inhibitor; IC50=0.065μM; curbs IL-1β; used in inflammation studies.Fórmula:C25H25NO5Pureza:98%Cor e Forma:SolidPeso molecular:419.478A8
CAS:<p>8A8 is a potent NO inhibitor with proinflammatory factor properties, exhibiting an IC50 of 4.7 μM.</p>Fórmula:C36H37BrClN5O9Pureza:98%Cor e Forma:SolidPeso molecular:799.06AN-3485
CAS:AN-3485 is a Toll-Like Receptor(TLR) inhibitor (IC50s: 18 to 580 nM).Fórmula:C14H13BClNO3Cor e Forma:SolidPeso molecular:289.52APY0201
CAS:<p>APY0201: potent, specific ATP-competitive PIKfyve inhibitor; IC50=5.2 nM; blocks PtdIns3P to PtdIns(3,5)P2 conversion.</p>Fórmula:C23H23N7OPureza:98% - 99.74%Cor e Forma:SolidPeso molecular:413.48CYPMPO
CAS:CYPMPO traps hydroxyl/superoxide radicals; decays in UV/H2O2 (15min) & hypoxanthine/xanthine (51min); outperforms DEPMPO in stability & shelf-life.Fórmula:C10H18NO4PCor e Forma:SolidPeso molecular:247.23
