Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(62 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3055 produtos de "Imunologia e Inflamação"
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MSU38225
CAS:<p>MSU38225, an Nrf-2 inhibitor, elevates reactive oxygen species (ROS) levels and suppresses the proliferation of human lung cancer cells.</p>Fórmula:C21H19N3Cor e Forma:SolidPeso molecular:313.4(+)-DHMEQ
CAS:(+)-DHMEQ is an antioxidant transcription factor Nrf2 activator. (+)-DHMEQ is the enantiomer of (-)-DHMEQ.Fórmula:C13H11NO5Cor e Forma:SolidPeso molecular:261.23ROS inducer 3
CAS:<p>ROS inducer 3 is a ROS inducer used as a bactericide in the study of resistant plant bacterial diseases, inhibiting Streptomyces.</p>Fórmula:C22H22F3N3OPureza:99.88%Cor e Forma:SolidPeso molecular:401.43ROS inducer 2
CAS:<p>ROS inducer 2 is a reactive oxygen species (ROS) inducer with antibacterial activity, inhibiting Axonobacter species.</p>Fórmula:C23H24F3N3OPureza:99.53% - 99.97%Cor e Forma:SolidPeso molecular:415.45Isofezolac
CAS:<p>Isofezolac (LM 22070), a NSAID, inhibits prostaglandin-synthetase, offering powerful anti-inflammatory and antipyretic effects.</p>Fórmula:C23H18N2O2Cor e Forma:SolidPeso molecular:354.4DSR-6434
CAS:<p>DSR-6434 is a selective agonist of TLR7 with antitumor effect. DSR-6434 exhibits EC50s of 7.2 nM and 4.6 nM for human and mouse.</p>Fórmula:C19H28N8O2Pureza:99.78%Cor e Forma:SolidPeso molecular:400.48MIF-IN-1
CAS:<p>MIF-IN-1 (compound 14) inhibits MIF, a cytokine linked to diseases, with pIC50 of 6.87.</p>Fórmula:C15H13N3O5Cor e Forma:SolidPeso molecular:315.28NF-κB-IN-2
CAS:<p>NF-κB-IN-2 inhibits canonical NF-κB signaling induced by TNF-α in PC-3 cells.</p>Fórmula:C15H18O3Cor e Forma:SolidPeso molecular:246.3IND24
CAS:<p>IND24 has anti-prion activity and can be used to study neurodegenerative diseases.</p>Fórmula:C21H17N3SPureza:99.64%Cor e Forma:SolidPeso molecular:343.44Phox-I1
CAS:<p>Phox-I1 is a NOX2 inhibitor targeting the interactive site of p67phox with Rac GTPase.</p>Fórmula:C23H19N3O4Pureza:98%Cor e Forma:SolidPeso molecular:401.41Methyl aminolevulinate
CAS:<p>Methyl aminolevulinate, a prodrug for protoporphyrin IX, sensitizes in PDT.</p>Fórmula:C6H11NO3Pureza:98%Cor e Forma:SolidPeso molecular:145.16BAY32-5915
CAS:<p>BAY32-5915 is a selective inhibitor of IKKalpha.</p>Fórmula:C10H7NO3Pureza:96.48% - 97%Cor e Forma:Yellow Crystalline PowderPeso molecular:189.17Dihydrolipoic acid
CAS:<p>Dihydrolipoic acid (USAF XR-12), a dithiol carboxylic acid, is a potent antioxidant active against various reactive oxygen species at 0.01-0.5 mM.</p>Fórmula:C8H16O2S2Pureza:97.51%Cor e Forma:Yellow To Orange LiquidPeso molecular:208.34AI-3
CAS:<p>Nrf2/Keap1 and Keap1/Cul3 interaction inhibitor</p>Fórmula:C11H13ClO3S2Pureza:98%Cor e Forma:SolidPeso molecular:292.8STING Agonist 1a
CAS:<p>STING agonist 1a activates STING, induces IRF-SEAP, IFN-β, IL-6, CXCL10 (EC50=16.77 µM); effects reversed by STING KO/inhibitor H-151.</p>Fórmula:C19H11Cl2N5OCor e Forma:SolidPeso molecular:396.23TPO agonist 1
CAS:TPO agonist 1 is a thrombopoietin agonist. It would be useful as promoters of thrombopoiesis and megakaryocytopoiesis to treat thrombocytopenia.Fórmula:C25H22N8O2Pureza:98%Cor e Forma:SolidPeso molecular:466.49ABD-350
CAS:<p>ABD-350 is ligand-induced inhibitor of nuclear factor kappaB phosphorylation.</p>Fórmula:C19H22F2O2Cor e Forma:SolidPeso molecular:320.37Etoricoxib HCl
CAS:<p>Etoricoxib HCl is a synthetic NSAID that inhibits COX-2, blocking prostaglandin production.</p>Fórmula:C18H16Cl2N2O2SCor e Forma:SolidPeso molecular:395.30Asperbisabolane L
<p>Asperbisabolane L, a sesquiterpenoid, combats inflammation by blocking NF-κB signaling and NO in BV-2 cells.</p>Fórmula:C12H14O3Cor e Forma:SolidPeso molecular:206.24PHA-408
CAS:<p>PHA-408 is a novel potent, highly selective and ATP-competitive inhibitor of IKB kinase-2.</p>Fórmula:C29H27ClFN7O2Pureza:98%Cor e Forma:SolidPeso molecular:560.02SMA-12b
CAS:<p>SMA-12b is an analog of the immunomodulatory parasite product ES-62 that has immunomodulatory activity and can be used in the study of rheumatoid arthritis.</p>Fórmula:C13H22INO2SPureza:98.52% - 99.16%Cor e Forma:SolidPeso molecular:383.29(R)-MLT-985
CAS:<p>(R)-MLT-985 (compound 11) is a MALT1 protease inhibitor with IC50 of 3 nM, also blocking IL-2 in Jurkat cells and ABC-DLBCL cell growth.</p>Fórmula:C17H15Cl2N9O2Cor e Forma:SolidPeso molecular:448.27546C88
CAS:<p>546C88 is an inhibitor of nitric oxide synthase.</p>Fórmula:C7H17ClN4O2Pureza:98%Cor e Forma:SolidPeso molecular:224.69MIF-IN-5
CAS:<p>MIF-IN-5: reversible MIF inhibitor, IC50 4.8 μM, Ki 3.3 μM.</p>Fórmula:C18H14FN5O2Cor e Forma:SolidPeso molecular:351.33NF-κB/PON1-IN-1
CAS:<p>NF-κB/PON1-IN-1 (Compound 16) is an NF-κB/PON1 pathway inhibitor with antioxidant activity (IC50: 45.76 μM) and hepatoprotective activity.</p>Fórmula:C20H16N6O4S2Cor e Forma:SolidPeso molecular:468.51AN-3485
CAS:<p>AN-3485 is a Toll-Like Receptor(TLR) inhibitor (IC50s: 18 to 580 nM).</p>Fórmula:C14H13BClNO3Cor e Forma:SolidPeso molecular:289.52COX-2-IN-18
CAS:<p>COX-2-IN-18 is a potent COX-2 inhibitor similar to Celecoxib, showing promise in cancer research. IC50=0.775μM.</p>Fórmula:C18H19N3O3S2Cor e Forma:SolidPeso molecular:389.49Isoandrographolide
CAS:<p>Isoandrographolide induces cell differentiation, protects the liver, blocks NLRP3, and reduces silicosis in mice.</p>Fórmula:C20H30O5Cor e Forma:SolidPeso molecular:350.45MD13
<p>MD13 is a macrophage migration inhibitor (MIF) oriented PROTAC (Ki value: 71 nM). MD13 can be used to study cancer.</p>Cor e Forma:LiquidJAK2/STAT3-IN-1
CAS:<p>JAK2/STAT3-IN-1 is a GP130 inhibitor with anti-tumor effects and can be used to study inflammation, autoimmunity and cancer.</p>Fórmula:C34H35BrF3N5O2Pureza:97.35%Cor e Forma:SolidPeso molecular:682.57MIF-IN-4 hydrochloride
CAS:<p>MIF-IN-4 hydrochloride inhibits MIF, a cytokine; has pIC50 of 5.01-6, affecting macrophage movement.</p>Fórmula:C26H29ClN6O2Cor e Forma:SolidPeso molecular:493.01NOS-IN-3
CAS:<p>NOS-IN-3: potent, selective iNOS inhibitor; IC50 of 4.6 µM; spares eNOS; low toxicity; potential for septic shock treatment.</p>Fórmula:C10H15N3OCor e Forma:SolidPeso molecular:193.25Sulfo-ara-F-NMN
CAS:<p>Sulfo-ara-F-NMN: cell-permeable, NMN analogue, activates SARM1, inhibits CD38 (IC50 ~10μM), induces cADPR, NAD loss, non-apoptotic death.</p>Fórmula:C11H14FN2O6PSPureza:98%Cor e Forma:SolidPeso molecular:352.28WIN 54954
CAS:<p>WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and may be used in the study of small ribonucleic acid virus infections.</p>Fórmula:C18H20Cl2N2O3Pureza:98.98%Cor e Forma:SolidPeso molecular:383.27Nexinhib20
CAS:<p>Nexinhib20 is an inhibitor of exosome synthesis and transport with anti-inflammatory activity, inhibits RAB27A and neutral sphingomyelinase 2 (nSMase2) nsMase2.</p>Fórmula:C15H16N4O3Pureza:99.89%Cor e Forma:SolidPeso molecular:300.31Tyrosinase-IN-12
CAS:<p>Tyrosinase-IN-12(Non-competitive tyrosinase inhibitor) is a potent non-competitive tyrosinase inhibitor with an IC50 of 49.33 ± 2.64 µM and a Ki of 31.25 ± 0.25</p>Fórmula:C16H12ClN3SPureza:99.2%Cor e Forma:SoildPeso molecular:313.8QM385
CAS:<p>QM385 is a potent inhibitor of sepiapterin reductase (SPR)(IC50 of 1.49 nM).</p>Fórmula:C17H18F3N7O2Pureza:98%Cor e Forma:SolidPeso molecular:409.37Avenanthramide-C methyl ester
CAS:<p>Avenanthramide-C methyl ester blocks IKK/IκB phosphorylation, inhibits NF-κB, and reduces IL-6, IL-8, MCP-1 in endothelial cells (IC50 ~40 μM).</p>Fórmula:C17H15NO6Cor e Forma:SolidPeso molecular:329.3Mercaptoethylguanidine (MEG) (dihydrobromide)
CAS:<p>MEG dihydrobromide inhibits inducible nitric oxide synthase and scavenges peroxynitrite, potentially aiding in inflammatory bowel disease studies.</p>Fórmula:C3H11Br2N3SCor e Forma:SolidPeso molecular:281.01TML-6
CAS:<p>TML-6, an oral derivative of curcumin, may help in Alzheimer's research by targeting amyloid production and various molecular pathways.</p>Fórmula:C30H37NO7Pureza:99.71%Cor e Forma:SolidPeso molecular:523.62AHR-6293
CAS:<p>AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.</p>Fórmula:C15H12ClNO3Cor e Forma:SolidPeso molecular:289.71UPF-648 sodium salt
CAS:<p>UPF-648 sodium salt is an inhibitor of kynurenine 3-monooxygenase (KMO) and exhibits highly active at 1 uM (81 ± 10% KMO inhibition).</p>Fórmula:C11H8Cl2NaO3Pureza:98%Cor e Forma:SolidPeso molecular:282.07AL-8417
CAS:<p>AL-8417 is an enzyme inhibitor with antioxidant, anti-inflammatory, and cytostatic properties; prevents vitrectomy-induced lens alterations.</p>Fórmula:C29H34O5Pureza:98%Cor e Forma:SolidPeso molecular:462.58AVE3085
CAS:AVE3085 is an enhancer of endothelial nitric oxide synthase that restores endothelial function and lowers blood pressure in spontaneously hypertensive rats.Fórmula:C17H13F2NO3Pureza:99.87%Cor e Forma:SolidPeso molecular:317.29Gue1654
CAS:<p>Gue1654 is an OXE-R inhibitor and cardiomyocyte apoptosis.Gue1654 can be used for the study of cardiovascular diseases.</p>Fórmula:C23H17N3OS3Pureza:98.02% - 98.04%Cor e Forma:SolidPeso molecular:447.6IMD-ferulic
<p>IMD-ferulic, a compound that forms covalent bonds, acts as an NF-κB modulator, enhancing the adjuvanticity of small molecule immune potentiators.</p>Fórmula:C36H41N7O4Cor e Forma:SolidPeso molecular:635.76Cyclic-di-GMP diammonium
CAS:<p>C-di-GMP diammonium activates STING, regulates biofilms, motility, and virulence in bacteria.</p>Fórmula:C20H30N12O14P2Cor e Forma:SolidPeso molecular:724.47TLR7/8 agonist 4
CAS:<p>TLR7/8 agonist 4 (compound 41) is a potent agonist of TLR7/8 with anti-cancer activity [1].</p>Fórmula:C18H24N6Cor e Forma:SolidPeso molecular:324.42BPK-29
CAS:BPK-29 disrupts NR0B1 binding and modifies C274, inhibiting growth in KEAP1-mutant cancers.Fórmula:C26H32ClN3O3Pureza:98%Cor e Forma:SolidPeso molecular:470DDO-7263
CAS:<p>DDO-7263, a 1,2,4-Oxadiazole, boosts Nrf2 by binding Rpn6, blocking 26S proteasome assembly, and has anti-inflammatory effects.</p>Fórmula:C14H9F2N3OPureza:99.85%Cor e Forma:SolidPeso molecular:273.24
