Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(62 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3055 produtos de "Imunologia e Inflamação"
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Resiniferatoxin
CAS:<p>Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist.Cost-effective and quality-assured.</p>Fórmula:C37H40O9Pureza:93.08% - 99.34%Cor e Forma:SolidPeso molecular:628.71h-NTPDase8-IN-1
CAS:h-NTPDase8-IN-1 is a specific aminosulfonylbenzamide inhibitor of h-NTPDases8, which can be used to study diseases caused by aberrant h-NTPDase expression.Fórmula:C10H10ClNO4SPureza:98.78% - 99.59%Cor e Forma:SolidPeso molecular:275.71Thiodigalactoside
CAS:<p>Thiodigalactoside (TDG), a non-metabolizable disaccharide, serves as an orally active, potent galectin (GAL) inhibitor, exhibiting Kd values of 24 μM and 49 μM</p>Fórmula:C12H22O10SPureza:99.90%Cor e Forma:SolidPeso molecular:358.36C3a Receptor Agonist
CAS:<p>C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.</p>Fórmula:C27H35N3O2Pureza:99.76%Cor e Forma:SolidPeso molecular:433.59NFAT Transcription Factor Regulator-1
CAS:<p>NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).</p>Fórmula:C17H10F6N4O2Pureza:99.90%Cor e Forma:SolidPeso molecular:416.28BRD56491
CAS:<p>BRD56491 is a small molecule ROS enhancer and a bioprobe for the detection of cancer.</p>Fórmula:C20H14O2Pureza:99.89%Cor e Forma:SolidPeso molecular:286.32GSK2983559 free acid
CAS:<p>GSK2983559 free acid selectively inhibits RIP2, reducing inflammatory cytokines in human bowel disease.</p>Fórmula:C21H23N4O7PS2Pureza:97.8700% - 98.61%Cor e Forma:SolidPeso molecular:538.53SM360320
CAS:<p>SM360320 (CL-087) is a selective TLR7 agonist that blocks HCV replication in hepatocytes and aids immunology research.</p>Fórmula:C15H17N5O3Pureza:99.13%Cor e Forma:SolidPeso molecular:315.33Phox-I2
CAS:<p>Phox-I2 is an NOX2-specific inhibitor. Phox-I2 reverts ROS-accumulation and leads to refusion of mitochondrial networks.</p>Fórmula:C18H15N3O4Pureza:99.73%Cor e Forma:SolidPeso molecular:337.33Desmosterol
CAS:<p>Desmosterol (24-Dehydrocholesterol) is a cholesterol biosynthesis intermediate that inhibits macrophage inflammatory vesicle activation .</p>Fórmula:C27H44OPureza:>99.99%Cor e Forma:SolidPeso molecular:384.64Azalanstat
CAS:<p>Azalanstat (RS 21607) is a mammalian lanosterol 14-alpha-demethylase inhibitor with hypocholesterolemic activity.</p>Fórmula:C22H24ClN3O2SPureza:99.41% - 99.85%Cor e Forma:SolidPeso molecular:429.96SP-100030
CAS:SP-100030: Strong NF-κB/AP-1 inhibitor, IC50=50 nM. Reduces IL-2, IL-8, TNF-alpha, and murine CIA.Fórmula:C14H5ClF9N3OPureza:99.79%Cor e Forma:SolidPeso molecular:437.65CT-2584
CAS:<p>CT-2584: angiogenesis & lysophosphatidic acid transferase inhibitor; alters phospholipid synthesis, increasing PI in tumor cells.</p>Fórmula:C30H55N5O3Pureza:97.68% - 99.77%Cor e Forma:SolidPeso molecular:533.79ABT-963
CAS:<p>ABT-963: COX-2 inhibitor for osteoarthritis/pain with high selectivity, potency, and gastric safety.</p>Fórmula:C22H22F2N2O5SPureza:98% - 99.85%Cor e Forma:SolidPeso molecular:464.48EG00229
CAS:<p>EG00229 blocks VEGF-A/NRP1 binding, IC50 of 3 μM; doesn't affect VEGFR-1/2. It's an NRP1 antagonist.</p>Fórmula:C19H20F3N7O7S3Pureza:98.23%Cor e Forma:SolidPeso molecular:611.6CPS-11
CAS:<p>CPS-11, a Thalidomide analogue, shows potent, broad antitumor activity, especially in multiple myeloma cells.</p>Fórmula:C14H12N2O5Pureza:99.8% - 99.98%Cor e Forma:SolidPeso molecular:288.26Letosteine
CAS:<p>Letosteine, an oral expectorant, treats acute/chronic respiratory diseases by dissolving mucus and reducing inflammation.</p>Fórmula:C10H17NO4S2Pureza:96.03%Cor e Forma:SolidPeso molecular:279.38BBIQ
CAS:<p>BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of 59.1</p>Fórmula:C21H22N4Pureza:99.71%Cor e Forma:SolidPeso molecular:330.43NO-prednisolone
CAS:<p>NO-prednisolone (NCX-1015) is a compound that effectively stimulates the production of IL-10 in vivo.</p>Fórmula:C29H33NO9Pureza:98.65%Cor e Forma:SolidPeso molecular:539.57SC-75416
CAS:SC-75416, a cyclooxygenase-2 (COX-2) inhibitor, is used potentially for the treatment of postoperative inflammation.Fórmula:C15H14ClF3O3Pureza:98.67% - 98.67%Cor e Forma:SolidPeso molecular:334.72CDDO-EA
CAS:CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.Fórmula:C33H46N2O3Pureza:99.66%Cor e Forma:SolidPeso molecular:518.73Tilomisole
CAS:Tilomisole (Wy 18251) is an oral anti-inflammatory and immunomodulatory benzimidazole thiazole, used in cancer and inflammation research.Fórmula:C17H11ClN2O2SPureza:99.21%Cor e Forma:SolidPeso molecular:342.8Cindunistat
CAS:<p>Cindunistat (free base) is an orally available selective iNOS inhibitor for the study of arthritis.</p>Fórmula:C8H17N3O2SPureza:99% - >99.99%Cor e Forma:SolidPeso molecular:219.3APX-115
CAS:<p>APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4).</p>Fórmula:C17H18ClN3OPureza:98.62%Cor e Forma:SolidPeso molecular:315.8YM-53403
CAS:<p>YM-53403: Antiviral that combats both RSV subgroup A/B, treats respiratory infections.</p>Fórmula:C36H29N3O3SPureza:98.49% - 98.85%Cor e Forma:SolidPeso molecular:583.7B022
CAS:<p>B022 is an NF-κB-induced kinase (NIK) inhibitor that protects the liver from inflammation and injury caused by oxidative stress and toxins.</p>Fórmula:C19H16ClN5OSPureza:99.74%Cor e Forma:SolidPeso molecular:397.88BN-82451 2HCl
CAS:BN-82451, a cyclooxygenase inhibitor, is used potentially for the treatment of Huntington’s disease.Fórmula:C18H28Cl2N2OSPureza:99.84% - >99.99%Cor e Forma:SolidPeso molecular:391.4HS271
CAS:<p>HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM).</p>Fórmula:C21H24F3N5O2Pureza:98.79%Cor e Forma:SolidPeso molecular:435.44M62812
CAS:<p>TLR4 inhibitor blocks LPS-induced NF-κB (IC50=2.4μg/mL), cytokines in PBMCs/HUVECs, and extends life in septic shock mice.</p>Fórmula:C13H13Cl2N3OSPureza:99.07%Cor e Forma:SolidPeso molecular:330.23ER-34122
CAS:<p>ER-34122, a novel orally available dual 5-lipoxygenase/cyclooxygenase inhibitor with potent anti-inflammatory activity.</p>Fórmula:C27H26ClN3O5Pureza:>99.99%Cor e Forma:SolidPeso molecular:507.96NLRP3-IN-10
CAS:<p>NLRP3-IN-10 (ZVN26391) is a strong NLRP3 inhibitor, IC50 251.1 nM, that reduces IL-1β and ASC speck, hindering inflammasome activation.</p>Fórmula:C17H14BrFO3Pureza:99.06%Cor e Forma:SolidPeso molecular:365.19Zharp2-1
CAS:<p>Zharp2-1 is a RIPK2 inhibitor that alleviates MDP-induced peritonitis symptoms in mice and can be used to study inflammatory bowel disease (IBD).</p>Fórmula:C19H18N3O2PSPureza:99.41%Cor e Forma:SolidPeso molecular:383.4IRAK4-IN-20
CAS:<p>IRAK4-IN-20 is a potent and orally active IRAK4 inhibitor (IC50:3.55 nM).</p>Fórmula:C22H25F3N4O3Pureza:98.09%Cor e Forma:SolidPeso molecular:450.45Rufigallol
CAS:<p>Rufigallol, an anthraquinone with six OH groups, induces DLC and fluoresces when aggregated, showing antimalarial effects with vitamin C and ketones.</p>Fórmula:C14H8O8Pureza:98.92% - 99.27%Cor e Forma:SolidPeso molecular:304.21LMT-28
CAS:<p>LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2.</p>Fórmula:C17H29NO4Pureza:99.88%Cor e Forma:SolidPeso molecular:311.42AHR antagonist 2
CAS:<p>AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively.</p>Fórmula:C20H17F3N4O3Pureza:99.38%Cor e Forma:SolidPeso molecular:418.37JC124
CAS:<p>JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.</p>Fórmula:C17H19ClN2O4SPureza:99.64%Cor e Forma:SolidPeso molecular:382.86IQP-0528
CAS:<p>IQP-0528: Potent NNRTI, blocks HIV entry, microbicidal gel, EC50: 0.2 nM for HIV-1, 100 nM for HIV-2.</p>Fórmula:C20H24N2O3Pureza:98.36% - >99.99%Cor e Forma:SolidPeso molecular:340.42IL-4-inhibitor-1
CAS:<p>IL-4 inhibitor: Binds IL-4 (Kd=1.8 μM), blocks activity (EC50=1.81 μM), selective vs. IL-13, stops IL-4-JAK1-STAT6 in THP-1 monocytes (EC50=3.1 μM).</p>Fórmula:C18H12FN3O2Pureza:98.78% - 99.53%Cor e Forma:SolidPeso molecular:321.31Complement C5-IN-1
CAS:Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).Fórmula:C24H32N2O6Pureza:98.27%Cor e Forma:SolidPeso molecular:444.52NFATc1-IN-1
CAS:<p>NFATc1-IN-1 (A04) inhibits RANKL-induced osteoclast formation with 1.57 μM IC50, blocking NFATc1 translocation.</p>Fórmula:C13H8F2INO2Pureza:99.64%Cor e Forma:SolidPeso molecular:375.11RIPK1-IN-9
CAS:<p>RIPK1-IN-9, a potent dihydronaphthone, selectively inhibits RIPK1 with IC50 of 2 nM (U937) and 1.3 nM (L929).</p>Fórmula:C26H25FN6O2Pureza:99.85%Cor e Forma:SolidPeso molecular:472.51ABI-1968
CAS:<p>ABI-1968 has antiviral and antitumor activity and can be used to study immune system diseases.</p>Fórmula:C35H58N5O6PPureza:98.54%Cor e Forma:SolidPeso molecular:675.839CPG-52364
CAS:<p>CPG-52364 is a small molecule compound that interacts between an endosomal TLR and its ligand and is a candidate for the treatment of psoriasis.</p>Fórmula:C27H36N6O3Pureza:99.99%Cor e Forma:SolidPeso molecular:492.61Rabeximod
CAS:<p>Rabeximod, an immunomodulator, eases autoimmune diseases, inhibits arthritis, and aids brain recovery post-injury by blocking inflammation.</p>Fórmula:C22H24ClN5OPureza:99.99%Cor e Forma:SolidPeso molecular:409.91R 61837
CAS:<p>R 61837 is a novel rhinovirus inhibitor, a substituted phenylpyridazinamine, with antiviral activity.</p>Fórmula:C16H20N4OPureza:99.53%Cor e Forma:SolidPeso molecular:284.36Totrombopag
CAS:<p>Totrombopag (SB559448) is a candidate compound for action on RSV polymerase.</p>Fórmula:C25H22N8O2Pureza:99.50%Cor e Forma:SolidPeso molecular:466.49AT791
CAS:<p>AT791 is an orally available TLR7 and TLR9 inhibitor, suppressing TLR7 and TLR9 signaling, used in autoimmune lupus research.</p>Fórmula:C23H31N3O3Pureza:99.88%Cor e Forma:SolidPeso molecular:397.51Epetirimod
CAS:<p>Epetirimod (S-30563) is a small molecule immunomodulator with antitumor and anti-infective activity for the study of papillomavirus infections.</p>Fórmula:C13H15N5Pureza:99.08% - 99.53%Cor e Forma:SolidPeso molecular:241.29RIG012
CAS:RIG012 is a potent RIG-I inhibitor with an IC50 value of 0.71 μM measured by NADH-coupled ATPase.RIG012 inhibited the expression of IFN-β and ISG hRsad2.Fórmula:C23H21NO3Pureza:99.48%Cor e Forma:SolidPeso molecular:359.42
