Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(62 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3055 produtos de "Imunologia e Inflamação"
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Dersalazine
CAS:<p>Dersalazine, a PAF inhibitor, reduces IL-17 to treat colitis in rodents, potentially aiding ulcerative colitis patients.</p>Fórmula:C35H32N6O4Pureza:99.62%Cor e Forma:SolidPeso molecular:600.67Biofor 389
CAS:<p>Biofor 389 (BF389) has anti-inflammatory activity and can be used to study arthritis.</p>Fórmula:C20H29NO3Pureza:98.84% - 99.97%Cor e Forma:SolidPeso molecular:331.45FK-330
CAS:<p>FK-330 (FR-260330) is a novel nitric oxide synthase inhibitor that prevents ischemia and reperfusion injury in rat liver transplantation.</p>Fórmula:C29H28ClF3N6O4Pureza:99.95%Cor e Forma:SolidPeso molecular:617.02Imeglimin
CAS:<p>Imeglimin: first oral antidiabetic in its class, targets liver, muscle, & pancreatic β-cells for type 2 diabetes.</p>Fórmula:C6H13N5Pureza:98.97%Cor e Forma:SolidPeso molecular:155.2Zabedosertib
CAS:<p>Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential.</p>Fórmula:C20H21F3N4O4SPureza:98.54%Cor e Forma:SolidPeso molecular:470.47T6167923
CAS:<p>T6167923 inhibits MyD88 signaling, binds TIR domain, blocks dimer formation, lowers SEAP activity, and has anti-inflammatory IC50s ~2.7 μM.</p>Fórmula:C17H20BrN3O3S2Pureza:99.28%Cor e Forma:SolidPeso molecular:458.39BIT225
CAS:BIT225 is an HIV-1 Vpu inhibitor with antiviral activity that inhibits HIV-1 replication in myeloid dendritic cells.Fórmula:C16H15N5OPureza:98.8%Cor e Forma:SolidPeso molecular:293.32Sonlicromanol hydrochloride
CAS:<p>Sonlicromanol hydrochloride (KH176 hydrochloride) is a ROS-redox modulator used in the treatment of mitochondrial diseases.</p>Fórmula:C19H29ClN2O3Pureza:99.53%Cor e Forma:SolidPeso molecular:368.9F092
CAS:<p>F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases.</p>Fórmula:C20H17N5O2Pureza:99.63%Cor e Forma:SolidPeso molecular:359.38Ezurpimtrostat hydrochloride
CAS:<p>Ethacrysta hydrochloride (GNS561 hydrochloride) is a PPT1 inhibitor with antifibrotic properties and may be used in studies of hepatocellular carcinoma.</p>Fórmula:C25H32Cl2N4Pureza:99.84%Cor e Forma:SolidPeso molecular:459.45NDT 9513727
CAS:NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.Fórmula:C36H35N3O4Pureza:99.21%Cor e Forma:SolidPeso molecular:573.68Rociclovir
CAS:<p>Rociclovir has antiviral activity and is used to treat viral infections.</p>Fórmula:C15H25N5O3Pureza:99.19%Cor e Forma:SolidPeso molecular:323.39DDG-39
CAS:DDG-39 (1-(2,3-dideoxy-2-fluoropentofuranosyl)cytosine) possesses antiviral activity with potent and selective anti-HIV-1 and HBV activity in cell culture.Fórmula:C9H12FN3O3Pureza:99.17% - >99.99%Cor e Forma:SolidPeso molecular:229.21Selnoflast
CAS:<p>Selnoflast (RO-7486967) is an orally active, potent and selective NLRP3 inhibitor for the study of coronary arteries and ulcerative colitis.</p>Fórmula:C20H29N3O3SPureza:98.54% - 99.66%Cor e Forma:SolidPeso molecular:391.53IL-2-IN-1
CAS:IL-2-IN-1 is a potent inhibitor of IL-2 (IC50: 1978 nM) and exhibits anti-proliferative effects.Fórmula:C17H12F6N4O2Pureza:99.6%Cor e Forma:SolidPeso molecular:418.29NLRP3/AIM2-IN-2
CAS:<p>NLRP3/AIM2-IN-2, potent species-specific NLRP3 and AIM2 inflammasome pyroptosis inhibitor; IC50 = 0.2392 ± 0.0233 μM.</p>Fórmula:C15H15NO3Pureza:99.67%Cor e Forma:SolidPeso molecular:257.28EIDD-2749
CAS:<p>EIDD-2749 (4'-Fluorouridine), an oral drug, inhibits RdRp, halts RSV/SARS-CoV-2 replication, and fights HCV/LCMV.</p>Fórmula:C9H11FN2O6Pureza:97.39%Cor e Forma:SolidPeso molecular:262.19TLR7/8-IN-1
CAS:<p>TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research.Cost-effective and quality-assured.</p>Fórmula:C29H40N8O2Pureza:99.83%Cor e Forma:SolidPeso molecular:532.68LDC7559
CAS:<p>LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.</p>Fórmula:C20H19N3O3Pureza:99.8%Cor e Forma:SoildPeso molecular:349.38FEN1-IN-3
CAS:<p>FEN1-IN-3 is a human flap endonuclease-1 ( hFEN1 ) inhibitor that stabilizes hFEN1 with an EC 50 of 6.8 μM .</p>Fórmula:C15H12N2O4Pureza:98.16%Cor e Forma:SolidPeso molecular:284.27CD73-IN-4
CAS:<p>CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor</p>Fórmula:C16H23ClN5O7PPureza:98.61%Cor e Forma:SolidPeso molecular:463.81IR-Crizotinib
CAS:<p>IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) inhibitor, with an IC50 of 3.381 μM for intracranial</p>Fórmula:C53H57Cl2FIN7OPureza:98%Cor e Forma:SolidPeso molecular:1024.88Benoxaprofen
CAS:<p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>Fórmula:C16H12ClNO3Pureza:98.87%Cor e Forma:SolidPeso molecular:301.72Stobadine
CAS:<p>Stobadine, a potent antioxidant, safeguards endoplasmic reticulum (ER) membrane fluidity against free radical-induced changes.</p>Fórmula:C13H18N2Pureza:98%Cor e Forma:SolidPeso molecular:202.3cGAS-IN-1
CAS:<p>cGAS-IN-1 (compound C20), a flavonoid that acts as a Cyclic GMP-AMP Synthase (cGAS) inhibitor, demonstrates IC50 values of 2.28 μM for human cGAS and 1.44 μM</p>Fórmula:C18H19NO8Cor e Forma:SolidPeso molecular:377.35Antitumor agent-114
CAS:<p>Antitumor Agent-114, a potent STING (stimulator of interferon genes) agonist, activates immune responses and diminishes tumor size in mouse breast cancer models</p>Fórmula:C39H50F2N10O13P2Pureza:98%Cor e Forma:SolidPeso molecular:966.82RIPK1-IN-16
CAS:<p>RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of RIPK1-mediated necroptosis in vivo.</p>Fórmula:C20H19N5O2SPureza:98%Cor e Forma:SolidPeso molecular:393.46NF-κB-IN-13
CAS:<p>NF-κB-IN-13 (compound 12) markedly suppresses LPS-induced NF-κB activation and NO synthesis in RAW264.7 macrophages, exhibiting anti-inflammatory properties [1</p>Fórmula:C20H20O5Pureza:98%Cor e Forma:SolidPeso molecular:340.37CD73-IN-6
CAS:<p>CD73-IN-6, serves as a potent inhibitor of CD73. This compound finds utility in cancer research [1].</p>Fórmula:C20H15N7O2Cor e Forma:SolidPeso molecular:385.38RPR-106541
CAS:RPR-106541, a GR agonist, is used potentially for the treatment of asthma.Fórmula:C24H34F2O4SCor e Forma:SolidPeso molecular:456.59ICy-Q
CAS:<p>ICy-Q, a NIR reagent activated by NQO-1, triggers pyroptosis in pancreatic cancer cells, aiding diagnosis.</p>Fórmula:C48H50I2N2O5Pureza:98%Cor e Forma:SolidPeso molecular:988.73CD38 inhibitor 2
CAS:<p>CD38 inhibitor 2 is a potent CD38 inhibitor ( IC 50 = 0.01 ~ 0.1 μΜ).</p>Fórmula:C19H24N6O3Cor e Forma:SolidPeso molecular:384.43WEHI-345
CAS:<p>WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production.</p>Fórmula:C22H23N7OPureza:>99.99%Cor e Forma:SolidPeso molecular:401.46IMD-biphenylC
CAS:<p>IMD-biphenylC: New, dual-action imidazoquinolinone dimer; inhibits tumor growth, low inflammation/toxicity.</p>Fórmula:C35H33N5O3Pureza:98%Cor e Forma:SolidPeso molecular:571.67Leteprinim
CAS:<p>Leteprinim (AIT 082 acid) is an hypoxanthine derivative that stimulates in vitro neurite outgrowth and the production of adenosine and neurotrophins from</p>Fórmula:C15H13N5O4Pureza:99.08%Cor e Forma:SolidPeso molecular:327.29IRAK4-IN-6
CAS:<p>IRAK4-IN-6 is an oral IRAK4 inhibitor with a 4 nM IC50, targeting MyD88 L265P mutant DLBCL.</p>Fórmula:C25H32N10O2Pureza:98%Cor e Forma:SolidPeso molecular:504.59(R)-IL-17 modulator 4
CAS:<p>(R)-IL-17 modulator 4, an R-isomer prodrug of IL-17 modulator 1, is potent and taken orally.</p>Fórmula:C27H34N6O2Cor e Forma:SolidPeso molecular:474.6MKA031
CAS:<p>MKA031 (compound 6y) is a non-competitive inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC50 of 1.7 μM.</p>Fórmula:C21H17N5O2SCor e Forma:SolidPeso molecular:403.46STING-IN-7
CAS:<p>STING-IN-7 (compound 21) serves as a potent inhibitor of the stimulator of interferon genes (STING) pathway, demonstrating an inhibitory concentration (IC50) of</p>Fórmula:C16H14ClN3OPureza:98%Cor e Forma:SolidPeso molecular:299.76Ginsenoside Rk1
CAS:<p>Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.</p>Fórmula:C42H70O12Pureza:98.46% - 99.13%Cor e Forma:SolidPeso molecular:767PROTAC IRAK4 degrader-8
CAS:<p>PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 of 15.5 nM [1].</p>Fórmula:C43H50ClF2N11O5Pureza:98%Cor e Forma:SolidPeso molecular:874.38FEN1-IN-6
CAS:<p>FEN1-IN-6 (compound 9) is a potent Flap endonuclease-1 (FEN1, IC50 = 10 nM) inhibitor, crucial for DNA damage repair in mammalian cells, and additionally</p>Fórmula:C12H8N2O5S2Pureza:98%Cor e Forma:SolidPeso molecular:324.33TIM-3-IN-2
CAS:<p>TIM-3-IN-2 is a Tim3 inhibitor that inhibits the action of TIM-3.TIM-3-IN-2 reverses TIM-3-mediated pro-inflammatory cytokine effects.</p>Fórmula:C25H23N3O6Pureza:98.93%Cor e Forma:SolidPeso molecular:461.47PF 184
CAS:<p>IKKβ inhibitor</p>Fórmula:C32H32ClFN6O4Pureza:98%Cor e Forma:SolidPeso molecular:619.09Anti-inflammatory agent 65
CAS:<p>Anti-inflammatory agent 65 (compound 29), a Hederagonic acid derivative, exhibits potent activity by inhibiting nitric oxide (NO) release, nuclear translocation</p>Fórmula:C49H71NO6S2Pureza:98%Cor e Forma:SoildPeso molecular:834.22(S)-BI 665915
CAS:<p>(S)-BI 665915 is an orally active inhibitor of oxadiazole-containing 5-lipoxygenase-activating protein (FLAP)(IC50 of 1.7 nM for FLAP binding)..</p>Fórmula:C24H26N8O2Pureza:98%Cor e Forma:SolidPeso molecular:458.52(Rac)-BAY-985
CAS:<p>(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy.</p>Fórmula:C27H30F3N9OPureza:98%Cor e Forma:SolidPeso molecular:553.58GW274150 dihydrochloride
CAS:<p>GW274150 (dihydrochloride) is a potent, selective inhibitor of human and rat inducible nitric oxide synthase (iNOS), exhibiting oral activity and NADPH-</p>Fórmula:C8H19Cl2N3O2SPureza:98%Cor e Forma:SolidPeso molecular:292.23IRAK inhibitor 3
CAS:IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.Fórmula:C21H21N5O4SPureza:98.86%Cor e Forma:SolidPeso molecular:439.49MAPK-IN-1
CAS:<p>MAPK-IN-1 inhibits MAPK for Alzheimer's research with anti-inflammatory effects, IC50 of 23.84 μM against AChE.</p>Fórmula:C19H18O4Cor e Forma:SolidPeso molecular:310.34
