Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(63 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3054 produtos de "Imunologia e Inflamação"
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NT-0796
CAS:<p>NT-0796 is an inflammasome NLRP3 inhibitor that inhibits NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.</p>Fórmula:C23H27N3O4Pureza:99.67%Cor e Forma:SolidPeso molecular:409.48CCG-63802
CAS:CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.Fórmula:C26H18N4O2SPureza:90%Cor e Forma:SolidPeso molecular:450.51CD73-IN-11
CAS:<p>CD73-IN-11 is a potent inhibitor used to prepare medication for cancer by blocking adenosine production, which fosters tumor growth.</p>Fórmula:C14H10F3N5O2Cor e Forma:SolidPeso molecular:337.26Cynandione A
CAS:Cynandione A is an acetophenone derived from Cynanchum wilfordii with anti-inflammatory activity.Fórmula:C16H14O6Pureza:99.62%Cor e Forma:SolidPeso molecular:302.28(R)-MALT1-IN-7
CAS:<p>(R)-MALT1-IN-7 (compound 142a) is a potent inhibitor of MALT1 protease and has potential for cancer research.</p>Fórmula:C19H17F3N8O2SCor e Forma:SolidPeso molecular:478.45TMV-IN-4
CAS:<p>TMV-IN-4, a TMV inhibitor, enhances plant defense and TMV resilience by interacting with helicase, increasing peroxidase and SOD activity.</p>Fórmula:C18H21NO4Cor e Forma:SolidPeso molecular:315.36FEN1-IN-7
CAS:<p>FEN1-IN-7 (compound 16), a selective Flap endonuclease-1 (FEN1) inhibitor with an IC50 of 18 nM, plays a role in DNA damage repair in mammalian cells.</p>Fórmula:C16H14N2O6SPureza:98%Cor e Forma:SolidPeso molecular:362.36(R)-IL-17 modulator 4
CAS:<p>(R)-IL-17 modulator 4, an R-isomer prodrug of IL-17 modulator 1, is potent and taken orally.</p>Fórmula:C27H34N6O2Cor e Forma:SolidPeso molecular:474.6TMV-IN-5
CAS:<p>TMV-IN-5 (compound 1a) serves as an antiviral/antifungal agent, specifically targeting and inhibiting the assembly of the tobacco mosaic virus (TMV) by binding</p>Fórmula:C22H23N3SCor e Forma:SolidPeso molecular:361.5IFN α-IFNAR-IN-1 hydrochloride
CAS:<p>IFN alpha-IFNAR-IN-1 HCl blocks IFN-α/IFNAR binding; IC50 2-8 μM in BM-pDCs' MVA-induced IFN-α response.</p>Fórmula:C18H18ClNSPureza:99.77%Cor e Forma:SolidPeso molecular:315.86ACHP Hydrochloride
CAS:<p>ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.</p>Fórmula:C21H25ClN4O2Pureza:99.83%Cor e Forma:SolidPeso molecular:400.9RPR-106541
CAS:RPR-106541, a GR agonist, is used potentially for the treatment of asthma.Fórmula:C24H34F2O4SCor e Forma:SolidPeso molecular:456.59ML-090
CAS:<p>ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).</p>Fórmula:C14H10N4Pureza:98.55%Cor e Forma:SolidPeso molecular:234.26TLR7 agonist 23
CAS:<p>TLR7 agonist23 (compound 12b) is a potent agonist of Toll-like receptor-7 (TLR7), with an EC50 value of 0.15 uM. It is suitable for research in immune diseases.</p>Fórmula:C21H22N4O2Cor e Forma:SolidPeso molecular:362.42Tyrosinase-IN-22
CAS:<p>Tyrosinase-IN-22 (compound 4) serves as a potent inhibitor for tyrosinase substrates, namely L-tyrosine and L-dopa, exhibiting inhibitory concentrations (IC50s) of 60 nM and 30 nM, respectively. Additionally, it demonstrates significant antioxidant and anti-melanogenic properties, making it suitable for related research endeavors [1].</p>Fórmula:C7H5ClN2SCor e Forma:SolidPeso molecular:184.64Fenquinotrione
CAS:<p>Fenquinotrione, a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor, exhibits IC50 values of 27.2 and 44.7 nM against HPPD from rice and Arabidopsis thaliana</p>Fórmula:C22H17ClN2O5Cor e Forma:SolidPeso molecular:424.83NVS-MALT1
CAS:<p>NVS-MALT1 is an allosteric inhibitor of MALT1 [1].</p>Fórmula:C24H27ClF3N5O4SCor e Forma:SolidPeso molecular:574.02TLR7 agonist 15
CAS:<p>TLR7 agonist 15 (compound 16b) is a potent activator of mouse macrophages and hPBMCs, demonstrating an EC50 of 18 nM.</p>Fórmula:C26H31N5OCor e Forma:SolidPeso molecular:429.56Bay 65-1942 (R form)
CAS:<p>Bay 65-1942 R form is the less active R-form of Bay 65-1942. Bay 65-1942 is a selective and ATP-competitive IKKβ inhibitor.</p>Fórmula:C22H25N3O4Pureza:98%Cor e Forma:SolidPeso molecular:395.45Dexamethasone palmitate
CAS:DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist & anti-inflammatory.Fórmula:C38H59FO6Pureza:99.28%Cor e Forma:SolidPeso molecular:630.87CCT374705
CAS:<p>CCT374705, an orally active BCL6 inhibitor, exhibits potent antiproliferative effects in vitro and effectively inhibits tumor growth in a lymphoma xenograft</p>Fórmula:C21H18ClF3N4O2Cor e Forma:SolidPeso molecular:450.84GW274150 phosphate
CAS:<p>GW274150 phosphate is a selective, orally active iNOS inhibitor with an IC50 of 0.2 μM. It mitigates experimental renal ischaemia-reperfusion injury.</p>Fórmula:C8H20N3O6PSPureza:98%Cor e Forma:SolidPeso molecular:317.3NLRP3-IN-17
CAS:<p>NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM.</p>Fórmula:C21H22N4O2SPureza:98%Cor e Forma:SolidPeso molecular:394.49Argininosuccinic acid disodium
CAS:<p>Argininosuccinic acid disodium, involved in the urea cycle's fourth step, is cleaved by argininosuccinate lyase (ASL) into arginine and fumarate.</p>Fórmula:C10H16N4Na2O6Pureza:98%Cor e Forma:SolidPeso molecular:334.24Glu-urea-Glu-NHS ester
CAS:<p>Compound 21, Glu-urea-Glu-NHS ester, an activated N-hydroxysuccinamide (NHS) ester derivative of Glu-urea-Glu, serves as a pharmacophore for conjugation to prostate specific membrane antigen (PSMA) inhibitors [1].</p>Fórmula:C27H43N3O11Cor e Forma:SolidPeso molecular:585.64EG01377
CAS:<p>EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.</p>Fórmula:C26H30N6O6S2Pureza:98%Cor e Forma:SolidPeso molecular:586.68IRAK inhibitor 3
CAS:<p>IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.</p>Fórmula:C21H21N5O4SPureza:98.86%Cor e Forma:SolidPeso molecular:439.49cGAS-IN-1
CAS:<p>cGAS-IN-1 (compound C20), a flavonoid that acts as a Cyclic GMP-AMP Synthase (cGAS) inhibitor, demonstrates IC50 values of 2.28 μM for human cGAS and 1.44 μM</p>Fórmula:C18H19NO8Cor e Forma:SolidPeso molecular:377.35CAY10464
CAS:<p>CAY10464 (AHR antagonist 7) is an AHR antagonist for the study of cancer and metabolic diseases.</p>Fórmula:C15H12Cl2OPureza:99.96%Cor e Forma:SolidPeso molecular:279.16ST 2825
CAS:<p>ST 2825 is a specific MyD88 dimerization inhibitor. ST2825 inhibition of IL-1β-mediated activation of NF-κB transcriptional activity.</p>Fórmula:C27H28Cl2N4O5SPureza:98%Cor e Forma:SolidPeso molecular:591.51GBT1118
CAS:<p>GBT1118 is an orally active allosteric modulator of haemoglobin oxygen affinity, enhancing tolerance to acute severe hypoxia and suitable for hypoxia research.</p>Fórmula:C19H20N2O4Pureza:99.69%Cor e Forma:SolidPeso molecular:340.37NLRP3-IN-9
CAS:<p>NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.</p>Fórmula:C12H13ClO3Pureza:99.64%Cor e Forma:SolidPeso molecular:240.68Thromboxane B3
CAS:<p>Thromboxane B3 (TXB3), the stable hydrolysis product of TXA3, is synthesized from eicosapentaenoic acid (EPA) through the action of COX and thromboxane synthase enzymes. This compound is biosynthesized in several tissues, including seminal vesicles, lungs, polymorphonuclear leukocytes (PMNL), and ocular tissues.</p>Fórmula:C20H32O6Cor e Forma:SolidPeso molecular:368.5TLR7/8 agonist 8
CAS:<p>TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of</p>Fórmula:C24H30N6OCor e Forma:SolidPeso molecular:418.53Ro26-4550
CAS:<p>Ro26-4550 is a competitive reversible inhibitor of interleukin-2 (IL-2) binding to IL-2R α-subunit (IC50 = 3 μM).</p>Fórmula:C26H30N4O3Pureza:98%Cor e Forma:SolidPeso molecular:446.54TLR9-IN-1
CAS:<p>TLR9-IN-1: selective, potent human TLR9 inhibitor (IC50: 7 nM), useful for researching immune-related diseases.</p>Fórmula:C23H31N7OCor e Forma:SolidPeso molecular:421.54IRAK4-IN-6
CAS:<p>IRAK4-IN-6 is an oral IRAK4 inhibitor with a 4 nM IC50, targeting MyD88 L265P mutant DLBCL.</p>Fórmula:C25H32N10O2Pureza:98%Cor e Forma:SolidPeso molecular:504.59MKA031
CAS:<p>MKA031 (compound 6y) is a non-competitive inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC50 of 1.7 μM.</p>Fórmula:C21H17N5O2SCor e Forma:SolidPeso molecular:403.46CD38 inhibitor 2
CAS:<p>CD38 inhibitor 2 is a potent CD38 inhibitor ( IC 50 = 0.01 ~ 0.1 μΜ).</p>Fórmula:C19H24N6O3Cor e Forma:SolidPeso molecular:384.43AMPCP
CAS:<p>AMPCP is an Ecto-5'-nucleotidase (CD73) inhibitor.</p>Fórmula:C11H15N5Na2O9P2Cor e Forma:SolidPeso molecular:469.19Nrf2-IN-1
CAS:<p>Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor. Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML).</p>Fórmula:C21H22ClN3O2Pureza:95.00% - 99.68%Cor e Forma:SolidPeso molecular:383.87Lobenzarit sodium
CAS:<p>Lobenzarit sodium (CCA) is an agent with the activity of antirheumatic and antioxidative.</p>Fórmula:C14H8ClNNa2O4Pureza:99.35%Cor e Forma:SolidPeso molecular:335.65Oxidized ATP trisodium salt
CAS:<p>Oxidized ATP trisodium salt (oATP) is a broad-spectrum inhibitor of P2 receptors, irreversibly antagonizing P2X7R activation and inhibiting c-reactive protein (</p>Fórmula:C10H11N5Na3O13P3Pureza:98%Cor e Forma:SolidPeso molecular:571.11PF 184
CAS:<p>IKKβ inhibitor</p>Fórmula:C32H32ClFN6O4Pureza:98%Cor e Forma:SolidPeso molecular:619.09Leteprinim
CAS:<p>Leteprinim (AIT 082 acid) is an hypoxanthine derivative that stimulates in vitro neurite outgrowth and the production of adenosine and neurotrophins from</p>Fórmula:C15H13N5O4Pureza:99.08%Cor e Forma:SolidPeso molecular:327.29(Rac)-BAY-985
CAS:<p>(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy.</p>Fórmula:C27H30F3N9OPureza:98%Cor e Forma:SolidPeso molecular:553.58(S)-BI 665915
CAS:<p>(S)-BI 665915 is an orally active inhibitor of oxadiazole-containing 5-lipoxygenase-activating protein (FLAP)(IC50 of 1.7 nM for FLAP binding)..</p>Fórmula:C24H26N8O2Pureza:98%Cor e Forma:SolidPeso molecular:458.52STING-IN-7
CAS:<p>STING-IN-7 (compound 21) serves as a potent inhibitor of the stimulator of interferon genes (STING) pathway, demonstrating an inhibitory concentration (IC50) of</p>Fórmula:C16H14ClN3OPureza:98%Cor e Forma:SolidPeso molecular:299.76Aminoguanidine hemisulfate
CAS:<p>Aminoguanidine hemisulfate, an inhibitor of nitric oxide synthases (NOS) and reactive oxygen species (ROS), effectively suppresses ANE-induced ROS production in</p>Fórmula:CH6N4H2SO4Pureza:98%Cor e Forma:SolidPeso molecular:123.115PROTAC IRAK4 degrader-8
CAS:<p>PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 of 15.5 nM [1].</p>Fórmula:C43H50ClF2N11O5Pureza:98%Cor e Forma:SolidPeso molecular:874.38
