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Imunologia e Inflamação

Imunologia e Inflamação

Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.

Subcategorias de "Imunologia e Inflamação"

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Foram encontrados 3045 produtos de "Imunologia e Inflamação"

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  • Logotipo do CymitQuimica
    Targetmol
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    NLRP3-IN-6

    <p>NLRP3-IN-6 (Compound 34) is a selective inhibitor of the NLRP3 inflammasome.</p>
    Fórmula:C18H15ClN2O4S3
    Cor e Forma:Solid
    Peso molecular:454.97

    Ref: TM-T62808

  • E 5090
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    E 5090

    CAS:
    <p>E5090 is a novel orally active inhibitor of IL-1 generation. It also has anti-inflammatory properties.</p>
    Fórmula:C19H20O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:328.36

    Ref: TM-T24022

  • Cryptopleurine
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    Cryptopleurine

    CAS:
    <p>Cryptopleurine is an inhibitor of gene products associated with cell proliferation, survival, invasion and angiogenesis. It acts by targeting the NF-κB pathway.</p>
    Fórmula:C24H27NO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:377.48

    Ref: TM-T27091

  • Nrf2-ARE/hMAO-B/QR2 modulator 1
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    Nrf2-ARE/hMAO-B/QR2 modulator 1

    CAS:
    <p>Nrf2-ARE/hMAO-B/QR2 modulator 1 a resveratrol derivative activated the NRF2-ARE inhibit hMAO-B and QR2, promote hippocampal neurogenesis Alzheimer's disease .</p>
    Fórmula:C14H12N2O3
    Pureza:98.5%
    Cor e Forma:Solid
    Peso molecular:256.26

    Ref: TM-T60395

  • S-MTC acetate
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    S-MTC acetate

    CAS:
    <p>S-MTC acetate (S-Methyl-L-thiocitrulline acetate) serves as a potent inhibitor of inducible nitric oxide synthases and is especially effective in inhibiting the constitutive (neuronal) type rather than the inducible (endothelial) type.</p>
    Fórmula:C9H19N3O4S
    Cor e Forma:Solid
    Peso molecular:265.33

    Ref: TM-T201332

  • Logotipo do CymitQuimica
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    IRAK4-IN-12

    <p>IRAK4-IN-12 (compound 37) is a potent inhibitor of IRAK4 (IC50: 0.015 μM) with cellular pIRAK4 potency (IC50: 0.5 μM).</p>
    Fórmula:C24H31FN8O
    Cor e Forma:Solid
    Peso molecular:466.55

    Ref: TM-T62989

  • CD73-IN-18
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    CD73-IN-18

    CAS:
    <p>CD73-IN-18 (compound 35j) is an orally effective inhibitor of the extracellular 5'-nucleotidase (CD73) enzyme. It can be utilized in anticancer research.</p>
    Fórmula:C20H17N5O3
    Cor e Forma:Solid
    Peso molecular:375.38

    Ref: TM-T200672

  • mPGES1-IN-4
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    mPGES1-IN-4

    CAS:
    <p>mPGES1-IN-4 (compound 32) is a multi-substituted pyrimidine compound acting as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and significantly suppresses acute inflammation models in vivo.</p>
    Fórmula:C27H25F2N3O
    Cor e Forma:Solid
    Peso molecular:445.50

    Ref: TM-T200542

  • NLRP3-IN-53
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    NLRP3-IN-53

    CAS:
    <p>NLRP3-IN-53 (compound 1) is an NLRP3 inhibitor with an IC50 of 3.4nM.</p>
    Fórmula:C22H27N5O4
    Cor e Forma:Solid
    Peso molecular:425.48

    Ref: TM-T200482

  • Logotipo do CymitQuimica
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    IRAK4-IN-19

    <p>IRAK4-IN-19, an IRAK4 inhibitor (IC50: 4.3 nM), hampers IL23 synthesis and arthritis progression.</p>
    Fórmula:C25H26F2N8O
    Cor e Forma:Solid
    Peso molecular:492.52

    Ref: TM-T63315

  • VS-15
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    VS-15

    CAS:
    <p>VS-15 is a selective inhibitor of IDO1, specifically binding to its apo-heme form. Additionally, VS-15 serves as an inhibitor of iNOS.</p>
    Fórmula:C29H27N5O3
    Cor e Forma:Solid
    Peso molecular:493.56

    Ref: TM-T200480

  • MALT1-IN-11
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    MALT1-IN-11

    CAS:
    <p>MALT1-IN-11: MALT1 inhibitor, IC50 &lt;10-100 nM, reduces IL10, for cancer/autoimmune research.</p>
    Fórmula:C20H16F4N8O
    Cor e Forma:Solid
    Peso molecular:460.39

    Ref: TM-T73019

  • YM-I-26
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    YM-I-26

    CAS:
    <p>YM-I-26 is a selective inhibitor of the NLRP3 inflammasome. This compound enhances the phagocytic activity of β-amyloid in murine microglial BV2 cells and reduces the production of IL-1β and IL-10. YM-I-26 is useful for research into inflammation-related immunomodulatory activities.</p>
    Fórmula:C28H33ClN2O5S2
    Cor e Forma:Solid
    Peso molecular:577.16

    Ref: TM-T200649

  • (R)-Ketoprofen
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    (R)-Ketoprofen

    CAS:
    <p>(R)-Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that exhibits oral activity and analgesic properties. Unlike its counterpart, (R)-Ketoprofen does not significantly enhance the increase of inflammatory cytokines (such as Tumor Necrosis Factor (TNF) and Interleukin-1 (IL-1)) induced by LPS. However, it can inhibit the anti-inflammatory activity of (S)-Ketoprofen.</p>
    Fórmula:C16H14O3
    Cor e Forma:Solid
    Peso molecular:254.28

    Ref: TM-T200162

  • NOD1-IN-1
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    NOD1-IN-1

    CAS:
    <p>NOD1/2-IN-1 (Compound 2) is a potent inhibitor of RIPK2 with an IC50 value of 0.65 nM as determined by the ADP-Glo assay. It selectively inhibits the NOD1 pathway, with an IC50 of 33 nM, effectively blocking the production of pro-inflammatory cytokines and thereby reducing inflammatory responses. This compound has potential applications in the research of colitis.</p>
    Fórmula:C16H14ClN3O3
    Cor e Forma:Solid
    Peso molecular:331.75

    Ref: TM-T200671

  • BMY-25551
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    BMY-25551

    CAS:
    BMY-25551, a Mitomycin A analog, exhibits cytotoxicity 8 to 20 times greater than Mitomycin C against both murine and human tumor cell lines. It is applicable in research pertaining to cancer and hematological disorders.
    Fórmula:C17H21N3O7
    Cor e Forma:Solid
    Peso molecular:379.36

    Ref: TM-T201024

  • SLC7A11-IN-2
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    SLC7A11-IN-2

    CAS:
    <p>SLC7A11-IN-2 (Compound 1) is an inhibitor of SLC7A11/xCT. It disrupts the oxidative balance in HeLa cells by decreasing intracellular glutathione levels and increasing oxidative stress, thereby inducing cell death with an IC50 of 10.23 μM. Molecular dynamics simulations have demonstrated that SLC7A11-IN-2 exhibits a stronger binding affinity to SLC7A11 compared to Erastin. This compound is useful for research in the field of cervical cancer.</p>
    Fórmula:C19H24N4O3
    Cor e Forma:Solid
    Peso molecular:356.42

    Ref: TM-T200659

  • 4-Octylphenol
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    4-Octylphenol

    CAS:
    <p>4-Octylphenol is an endocrine disruptor with gender-specific effects on male germ cells, significantly reducing the mitotic index and the number of spermatogonia. It also causes inflammatory damage in the gills of carp by activating the complement system through the C3a/C3a receptor (C3a/C3aR) axis and C5a/C5a receptor 1 (C5a/C5aR1) axis. Furthermore, 4-Octylphenol induces immune suppression by disrupting the balance between helper T (Th) cells 1/Th2 and regulatory T (Treg)/Th17 cells, and triggers inflammatory damage through the Toll-like receptor 7 (Toll-like Receptor (TLR))/inhibitor κBα/nuclear factor κB (TLR7/IκBα/NF-κB) pathway.</p>
    Fórmula:C14H22O
    Cor e Forma:Solid
    Peso molecular:206.32

    Ref: TM-T201798

  • α-Gracinoic acid
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    α-Gracinoic acid

    CAS:
    <p>α-Gracinoic acid acts as an inhibitor of mPGES-1, exhibiting anti-inflammatory properties.</p>
    Fórmula:C29H42O4
    Cor e Forma:Solid
    Peso molecular:454.64

    Ref: TM-T200464

  • ASP-8731
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    ASP-8731

    CAS:
    <p>ASP8731 is a selective inhibitor of BACH1 that prevents inflammation and vascular occlusion, and induces fetal hemoglobin in sickle cell disease.</p>
    Fórmula:C20H21N5O4
    Cor e Forma:Solid
    Peso molecular:395.41

    Ref: TM-T201687