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Transportador de Membranas/Canal Iónico

Transportador de Membranas/Canal Iónico

Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.

Subcategorias de "Transportador de Membranas/Canal Iónico"

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Foram encontrados 2277 produtos de "Transportador de Membranas/Canal Iónico"

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  • BMS-199264 hydrochloride

    CAS:
    <p>BMS-199264 hydrochloride is selective inhibitor of mitochondrial F1F0 ATP hydrolase,inhibit decline of ATP and myocardial necrosis during myocardial ischemia.</p>
    Fórmula:C26H32Cl2N4O4S
    Pureza:99.86%
    Cor e Forma:Solid
    Peso molecular:567.53
  • NaV1.7 Blocker-801

    CAS:
    <p>NaV1.7 Blocker-801 is a potent NaV1.7 blocker.</p>
    Fórmula:C20H15ClF2N6O3S2
    Cor e Forma:Solid
    Peso molecular:524.95
  • Co 102862

    CAS:
    <p>Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies.</p>
    Fórmula:C14H12FN3O2
    Pureza:99.82%
    Cor e Forma:Solid
    Peso molecular:273.26
  • CP-409092

    CAS:
    <p>CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.</p>
    Fórmula:C17H19N3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:297.35
  • PF 04531083

    CAS:
    <p>PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.</p>
    Fórmula:C17H16ClN5O2
    Pureza:99.85%
    Cor e Forma:Solid
    Peso molecular:357.79
  • Ebio1

    CAS:
    <p>Ebio1, a selective activator of the voltage-gated potassium channel KCNQ2, enhances channel conductance by promoting the formation of an expanded gate at a saturation voltage of +50 mV, leading to increased channel activity [1].</p>
    Fórmula:C19H14FNO
    Cor e Forma:Solid
    Peso molecular:291.32
  • Aneratrigine

    CAS:
    <p>Aneratrigine is a blocker of the sodium channel protein type 9 subunit alpha, utilized in research on neuropathic pain diseases [1].</p>
    Fórmula:C19H20ClF2N5O2S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:487.97
  • (R)-Elexacaftor

    CAS:
    <p>(R)-Elexacaftor (compound 37) is the enantiomer of Elexacaftor (compound 1). (R)-Elexacaftor is a CFTR modulator with an EC50 of 0.29 μM for CFTR dF508.</p>
    Fórmula:C26H34F3N7O4S
    Pureza:98.991%
    Cor e Forma:Solid
    Peso molecular:597.65
  • BPO-27 racemate

    CAS:
    <p>BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.</p>
    Fórmula:C26H18BrN3O6
    Pureza:97.67% - 98.86%
    Cor e Forma:Solid
    Peso molecular:548.34
  • CLP257

    CAS:
    <p>CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4.</p>
    Fórmula:C14H14FN3O2S
    Pureza:99.5%
    Cor e Forma:Solid
    Peso molecular:307.34
  • KVI-020

    CAS:
    <p>KVI-020: oral Kv1.5 blocker (IC50: 480nM), hERG inhibitor (IC50: 15100nM), potent antiarrhythmic for AF studies.</p>
    Fórmula:C20H25N3O5S
    Cor e Forma:Solid
    Peso molecular:419.49
  • Chromanol 293B

    CAS:
    slow delayed rectifier K+ current (IKs) blocker
    Fórmula:C15H20N2O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:324.4
  • GDC-0310

    CAS:
    <p>GDC-0310 is a selective, orally available Nav1.7 inhibitor with an IC50 of 0.6 nM for human Nav1.7, suitable for pain research.</p>
    Fórmula:C25H29Cl2FN2O4S
    Pureza:99.877%
    Cor e Forma:Solid
    Peso molecular:543.48
  • GNE-0723

    CAS:
    <p>GNE-0723 is a selective positive allosteric modulator of the NMDA receptor, GluN2A.blood-brain barrier (BBB) and Dravet syndrome and Alzheimer's disease (AD).</p>
    Fórmula:C16H8ClF6N5OS
    Pureza:97.29% - 99.91%
    Cor e Forma:Solid
    Peso molecular:467.78
  • PF-4778574

    CAS:
    <p>PF-4778574 is a positive AMPA receptor allosteric modulation (EC50: 45 to 919 nM in different cells).</p>
    Fórmula:C19H22N2O3S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:390.52
  • Linaprazan

    CAS:
    <p>Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.</p>
    Fórmula:C21H26N4O2
    Pureza:99.54%
    Cor e Forma:Solid
    Peso molecular:366.46
  • OADS

    CAS:
    <p>OADS is an inhibitor of ClC-ec1 with low micromolar affinity. OADS has no specific effect on a CLC channel (ClC-1).</p>
    Fórmula:C30H42N2O8S2
    Cor e Forma:Solid
    Peso molecular:622.79
  • GSK 2833503A

    CAS:
    <p>GSK 2833503A: potent TRPC6/3 antagonist; IC50: 3-16/21-100 nM; &gt;63x selective; inhibits cardiac hypertrophy signaling.</p>
    Fórmula:C18H21ClFN3OS
    Cor e Forma:Solid
    Peso molecular:381.9
  • SLC13A5-IN-1

    CAS:
    <p>SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells).</p>
    Fórmula:C19H19Cl3N2O3S
    Pureza:99.67%
    Cor e Forma:Solid
    Peso molecular:461.79
  • URAT1 inhibitor 8

    CAS:
    <p>URAT1 Inhibitor 8 (example 247) serves as a highly potent inhibitor of URAT1, demonstrating an IC50 value of 0.001 μM.</p>
    Fórmula:C19H13ClFN3O4S
    Cor e Forma:Solid
    Peso molecular:433.84
  • MCT1-IN-2

    CAS:
    <p>SR13800 is a monocarboxylate transporter 1 (MCT1) inhibitor with cell-permeable.</p>
    Fórmula:C25H29N3O2S
    Cor e Forma:Solid
    Peso molecular:435.58
  • Mesendogen

    CAS:
    <p>Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7</p>
    Fórmula:C18H16ClF3N2OS
    Pureza:99.66%
    Cor e Forma:Solid
    Peso molecular:400.85
  • mGAT3/4-IN-2

    CAS:
    <p>mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.</p>
    Fórmula:C26H32ClN3OS2
    Cor e Forma:Solid
    Peso molecular:502.13
  • GDC-6599

    CAS:
    <p>GDC-6599 (Example 8) is an orally active inhibitor of the TRPA1 channel, potentially useful for researching TRPA1-mediated conditions, including pain [1].</p>
    Fórmula:C20H19ClN6O3
    Cor e Forma:Solid
    Peso molecular:426.86
  • BMS-986169

    CAS:
    <p>BMS-986169 is a high-affinity and selective negative allosteric modulator of the NMDA receptor GluN2B subunit, depression.</p>
    Fórmula:C23H27FN2O2
    Pureza:97.61%
    Cor e Forma:Solid
    Peso molecular:382.47
  • (-)-Bicuculline methochloride

    CAS:
    <p>(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.</p>
    Fórmula:C21H20ClNO6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:417.84
  • GSK3395879

    CAS:
    <p>GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).</p>
    Fórmula:C20H15F4N3O5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:485.41
  • Y-27152

    CAS:
    <p>Y-27152 is a prodrug of the KATP (Kir6) channel opener Y-26763 and is a long-acting K+ channel opener.</p>
    Fórmula:C21H22N2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:366.41
  • 6-Iodoamiloride

    CAS:
    <p>6-Iodoamiloride is a potent inhibitor of acid-sensing ion channel 1 (ASIC1), exhibiting an IC50 value of 88 nM.</p>
    Fórmula:C6H8IN7O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:321.08
  • MONIRO-1

    CAS:
    <p>MONIRO-1 blocks T/N-type Ca²⁺ channels: hCav2.2 (IC50: 34μM), hCav3.1 (3.3μM), hCav3.2 (1.7μM), hCav3.3 (7.2μM).</p>
    Fórmula:C23H24ClFN4O3
    Cor e Forma:Solid
    Peso molecular:458.92
  • LG 83-6-05

    CAS:
    <p>LG 83-6-05 is a novel kind of sodium channel blocking agent.</p>
    Fórmula:C21H30ClNO3S
    Cor e Forma:Solid
    Peso molecular:411.99
  • P-1075

    CAS:
    <p>P-1075 activates SUR2-KIR6 channels at 45 nM; may open mitoKATP channels and protect the heart.</p>
    Fórmula:C12H17N5
    Pureza:99.85%
    Cor e Forma:Solid
    Peso molecular:231.3
  • JYL-273

    CAS:
    <p>JYL-273 is a TRPV1 agonist.</p>
    Fórmula:C28H39NO4S
    Cor e Forma:Solid
    Peso molecular:485.68
  • UBP316

    CAS:
    <p>GluR5-containing kainate receptor antagonist</p>
    Fórmula:C20H19N3O6S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:429.45
  • Sudoterb free base

    CAS:
    <p>Sudoterb free base (Sudoterb) , also known as LL3858, is an anti-tubercular drug candidate.</p>
    Fórmula:C29H28F3N5O
    Pureza:97.26% - 98.85%
    Cor e Forma:Solid
    Peso molecular:519.56
  • GABAA receptor agent 2 TFA

    CAS:
    <p>Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.</p>
    Fórmula:C22H22F3N3O3
    Cor e Forma:Solid
    Peso molecular:433.42
  • URAT1 inhibitor 1

    CAS:
    <p>URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1) (IC50: 32 nM), has the potential to treat hyperuricemia associated with gout.</p>
    Fórmula:C19H15Br2N5O2S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:569.29
  • ADCI

    CAS:
    <p>ADCI inhibits voltage-activated sodium and NMDA channels; boosts dopamine metabolism in prefrontal cortex and nucleus accumbens.</p>
    Fórmula:C16H14N2O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:250.3
  • (+)-Bicuculline methiodide

    CAS:
    <p>(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.</p>
    Fórmula:C21H20INO6
    Pureza:99.24%
    Cor e Forma:Solid
    Peso molecular:509.29
  • Clobutinol hydrochloride

    CAS:
    <p>Clobutinol hydrochloride, an antitussive agent, influences heart rate and blood pressure, and is utilized in cough-related research [1] [2] [3].</p>
    Fórmula:C14H23Cl2NO
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:292.25
  • CS-526

    CAS:
    <p>CS-526 is a reversible proton pump inhibitor targeting the K+ site on H+,K+-ATPase, reducing gastric acid secretion and preventing mucosal lesions.</p>
    Fórmula:C20H22FN3O
    Cor e Forma:Solid
    Peso molecular:339.41
  • NMDA receptor modulator 6

    CAS:
    <p>NMDA receptor regulator 6 (Compound 183) is an effective NMDA receptor regulator and has research value in neurological disorders.</p>
    Fórmula:C20H17FN2O4S
    Cor e Forma:Solid
    Peso molecular:400.42
  • Pumaprazole

    CAS:
    <p>Pumaprazole (BY-841) is an antagonist of a reversible proton pump.</p>
    Fórmula:C19H22N4O2
    Pureza:99.91%
    Cor e Forma:Solid
    Peso molecular:338.4
  • Xeniafaraunol A

    CAS:
    <p>Xeniafaraunol A (compound 31) is a potent inhibitor of the transient receptor potential melastatin 7 (TRPM7) channel [1].</p>
    Fórmula:C20H28O2
    Cor e Forma:Solid
    Peso molecular:300.44
  • 8-Pcpt-cGMP

    CAS:
    <p>8-Pcpt-cGMP acts as an agonist for cyclic nucleotide-gated (CNG) channels with an EC50 of 0.5 μM and exhibits good membrane permeability. This compound is utilized in research to explore the role of CNG channels in visual and olfactory signal transduction.</p>
    Fórmula:C16H15ClN5O7PS
    Cor e Forma:Solid
    Peso molecular:487.81
  • MK-2295

    CAS:
    <p>MK-2295 is a potent TRPV1 antagonist. MK-2295 can be used in studies about the treatment of chronic pain.</p>
    Fórmula:C27H31FN6O2
    Pureza:98.83% - 99.44%
    Cor e Forma:Solid
    Peso molecular:490.57
  • ROMK-IN-32

    CAS:
    <p>ROMK-IN-32 is an inhibitor of the extra-renal medullary potassium channel (ROMK) (IC50: 35 nM) and also inhibits hERG (IC50: 22 μM).</p>
    Fórmula:C24H28N4O5
    Cor e Forma:Solid
    Peso molecular:452.5
  • N-Linolenoylethanolamine

    CAS:
    <p>N-Linolenoylethanolamine (18:3 NAE), an endocannabinoid, functions as a vanillin receptor (TRPV1) agonist [1].</p>
    Fórmula:C20H35NO2
    Cor e Forma:Solid
    Peso molecular:321.505
  • XR9051

    CAS:
    <p>XR9051, a synthetic derivative of a natural compound, potently reverses P-glycoprotein MDR (EC50 = 1.4 nM) by inhibiting cytotoxic binding.</p>
    Fórmula:C39H38N4O5
    Cor e Forma:Solid
    Peso molecular:642.74
  • Ritivixibat

    CAS:
    <p>Ritivixibat inhibits IBAT and modulates bile acids, used in research for cardiovascular, metabolic, GI, and liver diseases.</p>
    Fórmula:C26H36N2O5S2
    Cor e Forma:Solid
    Peso molecular:520.7
  • NO-711ME

    CAS:
    <p>NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.</p>
    Fórmula:C22H24N2O3
    Pureza:99.54%
    Cor e Forma:Solid
    Peso molecular:364.44
  • AC-4

    CAS:
    <p>AC-4 is a blocker of photoswitchable TRPV1 channel.</p>
    Fórmula:C26H25F3N4O2S
    Cor e Forma:Solid
    Peso molecular:514.56
  • MK-8153

    CAS:
    <p>MK-8153: Selective, potent ROMK inhibitor, orally active, IC50: ROMK EP 5 μM, hERG EP 34 μM; potential diuretic.</p>
    Fórmula:C24H28N2O6
    Cor e Forma:Solid
    Peso molecular:440.49
  • ARN 11391

    CAS:
    <p>ARN 11391 enhances the function of the IP3-gated calcium channel ITPR1 (Inositol 1,4,5-trisphosphate (IP3) receptor type 1), boosting intracellular calcium ion</p>
    Fórmula:C22H29N3O3
    Cor e Forma:Solid
    Peso molecular:383.49
  • Lingdolinurad

    CAS:
    <p>Lingdolinurad is a uric acid transporter protein inhibitor targeting hURAT1 for the study of hyperuricemia or gout.</p>
    Fórmula:C17H12BrN3O2
    Pureza:96.26%
    Cor e Forma:Solid
    Peso molecular:370.2
  • JYL-1511

    CAS:
    <p>JYL-1511 is the TRPV1 channel partial agonist.</p>
    Fórmula:C21H29N3O3S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:435.6
  • D-erythro-Sphingosine hydrochloride

    CAS:
    <p>D-erythro-Sphingosine HCl activates TRPM3 and dephosphorylates retinoblastoma protein.</p>
    Fórmula:C18H38ClNO2
    Cor e Forma:Solid
    Peso molecular:335.95
  • Licostinel

    CAS:
    <p>Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.</p>
    Fórmula:C8H3Cl2N3O4
    Pureza:98.02%
    Cor e Forma:Solid
    Peso molecular:276.03
  • APS3

    CAS:
    <p>APS3 is an inhibitor of GABA and nACh receptors, exhibiting an LC50 value of 7.2423 μg/mL against Plutella xylostella [1].</p>
    Fórmula:C18H7Cl2F6N5O5S2
    Cor e Forma:Solid
    Peso molecular:622.31
  • TPA 023

    CAS:
    <p>TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).</p>
    Fórmula:C20H22FN7O
    Pureza:99.75%
    Cor e Forma:Solid
    Peso molecular:395.43
  • TCS 46b

    CAS:
    <p>TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.</p>
    Fórmula:C22H23N3O
    Pureza:99.78% - 99.78%
    Cor e Forma:Solid
    Peso molecular:345.44
  • Kv3 modulator 2

    CAS:
    <p>Kv3 modulator 2 is a potent Kv3 channels modulator.has analgesic activity and is used in the prophylaxis or treatment of related disorders.</p>
    Fórmula:C21H21N3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:379.41
  • DNDS

    CAS:
    <p>DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).</p>
    Fórmula:C14H8N2Na2O10S2
    Pureza:99.92%
    Cor e Forma:Physical Description White Powder (Ntp 1992)
    Peso molecular:474.33
  • TRPC5-IN-3

    CAS:
    <p>TRPC5-IN-3 is a potent TRPC5 inhibitor (IC50= 10.75 nM).</p>
    Fórmula:C18H15ClF3N5O
    Cor e Forma:Solid
    Peso molecular:409.79
  • NS1219

    CAS:
    <p>NS1219, an isomer of NS1209, is a selective AMPA antagonist for studying stroke, neuropathic pain, and epilepsy.</p>
    Fórmula:C24H28N4O7S
    Cor e Forma:Solid
    Peso molecular:516.57
  • Pristinamycin IA

    CAS:
    <p>Pristinamycin IA (Mikamycin B) is a substrate for the P-glycoprotein and a cyclo-peptidic macrolactone antibiotic.</p>
    Fórmula:C45H54N8O10
    Pureza:97.44%
    Cor e Forma:Solid
    Peso molecular:866.96
  • Budiodarone

    CAS:
    <p>Budiodarone (ATI-2042) resembles amiodarone, potentially preventing atrial fibrillation.</p>
    Fórmula:C27H31I2NO5
    Cor e Forma:Solid
    Peso molecular:703.35
  • CFTR corrector 6

    CAS:
    <p>CFTR corrector 6, a potent CFTR potentiator, aids cystic fibrosis research and related disorders.</p>
    Fórmula:C22H13F4N9
    Cor e Forma:Solid
    Peso molecular:479.39
  • Kv3 modulator 3

    CAS:
    <p>Kv3 modulator 3 is a selective modulator of Kv3.1 and/or Kv3.2 and/or Kv3.3 channels .has analgesic activity for use in the prophylaxis o or treatment of pain.</p>
    Fórmula:C19H18N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:350.37
  • L-822179

    CAS:
    <p>L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.</p>
    Fórmula:C17H14N8O2
    Pureza:98.5% - 99.61%
    Cor e Forma:Solid
    Peso molecular:362.35
  • CGP36216 hydrochloride

    CAS:
    <p>CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].</p>
    Fórmula:C5H15ClNO2P
    Cor e Forma:Solid
    Peso molecular:187.6
  • (R)-Vanzacaftor

    CAS:
    <p>(R)-Vanzacaftor ((R)-VX-121) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator [1].</p>
    Fórmula:C32H39N7O4S
    Cor e Forma:Solid
    Peso molecular:617.76
  • Mioflazine

    CAS:
    <p>Mioflazine suppresses nucleoside uptake. Mioflazine is an orally active nucleoside transport inhibitor. It has the potential for sleep disorders treatment.</p>
    Fórmula:C29H30Cl2F2N4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:575.48
  • 6,2'-Dihydroxyflavone

    CAS:
    <p>6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.</p>
    Fórmula:C15H10O4
    Pureza:99.44% - 99.67%
    Cor e Forma:Solid
    Peso molecular:254.24
  • Potassium Channel Activator 1

    CAS:
    <p>Potassium Channel Activator 1 aids treatment of ADHD, schizophrenia, and mood disorders by targeting the dopaminergic system.</p>
    Fórmula:C19H23N3O3
    Pureza:99.86%
    Cor e Forma:Solid
    Peso molecular:341.4
  • A-1165442

    CAS:
    <p>A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.</p>
    Fórmula:C22H20ClF2N3O2
    Cor e Forma:Solid
    Peso molecular:431.86
  • Dibutyryl-cGMP sodium

    CAS:
    <p>Bt2cGMP sodium is a cGMP analog, activates PKG, inhibits platelet [3H]-arachidonate, and induces analgesia via K+ channels.</p>
    Fórmula:C18H24N5NaO9P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:508.38
  • Naltiazem

    CAS:
    <p>Naltiazem, a calcium channel antagonist, is used potentially for the treatment of arrhythmias, hypertension and myocardial infarction.</p>
    Fórmula:C26H28N2O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:464.58
  • Antiarrhythmic agent-1

    CAS:
    <p>Antiarrhythmic agent-1 (example I), functioning as an antiarrhythmic agent and an IKr potassium channel blocker (IC 50 &lt;1 μM), effectively inhibits cardiac</p>
    Fórmula:C25H27N3O4S
    Cor e Forma:Solid
    Peso molecular:465.56
  • Oct4 inducer-2

    CAS:
    <p>Oct4 Inducer-2, an OCT4 inducer, sustains hiPSC formation by enhancing endogenous OCT4 expression and has applications in anti-aging research [1].</p>
    Fórmula:C14H16N2O2S
    Cor e Forma:Solid
    Peso molecular:276.35
  • P2X3 antagonist 34

    CAS:
    <p>Potent P2X3 antagonist 34, oral, selective for human, rat, guinea pig receptors; IC50s: 25/92/126 nM; strong anti-tussive, no taste change.</p>
    Fórmula:C24H26F2N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:456.48
  • ML-252 hydrochloride

    CAS:
    <p>ML-252 is a potent, selective inhibitor of the Kv7.2 voltage-gated potassium channel, demonstrating an IC50 value of 69 nM in patch clamp assays. It exists as the (S)-enantiomer, which is significantly more effective than both its (R)-enantiomer counterpart and the racemic mixture, with respective IC50 values of 944 nM and 160 nM. ML-252 exhibits high selectivity for Kv7.2 over other potassium channel subtypes and shows minimal activity against more than 68 G protein-coupled receptors, various transporters, L- and N-type calcium channels, K_ATP, and hERG potassium channels. However, it does inhibit the melatonin MT1 receptor by 61% at a 10 µM concentration.</p>
    Fórmula:C20H24N2OHCl
    Cor e Forma:Solid
    Peso molecular:344.9
  • PHP 501 trifluoroacetate

    CAS:
    <p>GABAA antagonist</p>
    Fórmula:C20H21N3O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:319.4
  • AMPA-IN-1

    CAS:
    <p>AMPA-IN-1: Potent AMPA receptor inhibitor; key in regulating brain excitatory transmission and plasticity.</p>
    Fórmula:C23H12F2N4O2
    Cor e Forma:Solid
    Peso molecular:414.36
  • NMDA receptor modulator 4

    CAS:
    <p>NMDA receptor modulator 4 (Compound 169) can be used for the research of neurological disorder that is a potent modulator of NMDA receptor [1].</p>
    Fórmula:C13H9F3N2O3S
    Cor e Forma:Solid
    Peso molecular:330.28
  • PZ-II-029

    CAS:
    <p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>
    Fórmula:C18H15N3O3
    Pureza:99.79%
    Cor e Forma:Solid
    Peso molecular:321.33
  • BMT-108908

    CAS:
    <p>BMT-108908 is a Negative Allosteric Modulator. It is selective for the NR2B Subtype of The NMDA Receptor Impair Cognition in Multiple Domains.</p>
    Fórmula:C22H25FN2O2
    Cor e Forma:Solid
    Peso molecular:368.44
  • 3′-Acetate-ATP

    CAS:
    <p>3’-Acetate-ATP, an analogue of ATP and its acetylation product, exhibits maximum ultraviolet absorption at 259 nm in neutral aqueous solutions.</p>
    Fórmula:C12H18N5O14P3
    Cor e Forma:Solid
    Peso molecular:549.22
  • A 425619

    CAS:
    <p>A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonist</p>
    Fórmula:C18H14F3N3O
    Pureza:99.75%
    Cor e Forma:Solid
    Peso molecular:345.32
  • TRPC5 modulator-1

    CAS:
    <p>TRPC5 modulator-1 (Compound 9) is a TRPC5 modulator (IC50&lt;1 nM) that can be used to study neuropsychiatric disorders.</p>
    Fórmula:C23H27FN2O4
    Cor e Forma:Solid
    Peso molecular:414.47
  • 11-deoxy-PGF2a

    CAS:
    <p>11-deoxy-PGF2a is a thromboxane A2 receptor agonist that partially alleviates crowding in Lpar3(−/−) female embryos and induces smooth muscle contraction</p>
    Fórmula:C20H34O4
    Cor e Forma:Solid
    Peso molecular:338.48
  • Biricodar

    CAS:
    <p>Biricodar is a P-glycoprotein and MRP-1 modulator.</p>
    Fórmula:C34H41N3O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:603.71
  • U 89843A

    CAS:
    <p>U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.</p>
    Fórmula:C16H23N5
    Pureza:99.62%
    Cor e Forma:Solid
    Peso molecular:285.39
  • ADX71441

    CAS:
    <p>ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events &amp; volume, and may aid in alcoholism and bladder pain.</p>
    Fórmula:C19H15ClF2N4O4
    Cor e Forma:Solid
    Peso molecular:436.8
  • γ-Kainylglutamic acid

    CAS:
    <p>gamma-Kainylglutamic acid is a selective amino acid-induced neuroexcitation antagonist.</p>
    Fórmula:C15H22N2O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:342.34
  • Diproqualone

    CAS:
    <p>Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].</p>
    Fórmula:C12H14N2O3
    Cor e Forma:Solid
    Peso molecular:234.255
  • CP 154526

    CAS:
    <p>CRF1 receptor antagonist</p>
    Fórmula:C23H33ClN4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:400.99
  • Cavα2δ1&NET-IN-3

    CAS:
    <p>Cavα2δ1&amp;NET-IN-3 (example 216) is an inhibitor targeting both the α2δ subunit of voltage-gated calcium channels (VGCC) and the noradrenaline transporter (NET).</p>
    Fórmula:C24H30N6O2S
    Cor e Forma:Solid
    Peso molecular:466.6
  • p-fin4

    CAS:
    <p>p-fin4, a peptide, inhibits STEP-GluA2 interaction, Ki 0.4 μM; may enhance cognition, has anxiolytic and antidepressant effects.</p>
    Fórmula:C39H53N8O18P
    Cor e Forma:Solid
    Peso molecular:952.85
  • Adipiplon

    CAS:
    <p>Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.</p>
    Fórmula:C18H18FN7
    Cor e Forma:Solid
    Peso molecular:351.38