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Transportador de Membranas/Canal Iónico

Transportador de Membranas/Canal Iónico

Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.

Subcategorias de "Transportador de Membranas/Canal Iónico"

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Foram encontrados 2293 produtos de "Transportador de Membranas/Canal Iónico"

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  • O4I4
    Targetmol
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    O4I4

    CAS:
    <p>O4I4 is an OCT4-inducing compound capable of activating endogenous OCT4 and its associated signaling pathways, shown anti-aging effects.</p>
    Fórmula:C15H20N2S
    Pureza:99.74%
    Cor e Forma:Solid
    Peso molecular:260.4

    Ref: TM-T87051

  • Antidepressant agent 8
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    Antidepressant agent 8

    CAS:
    <p>Antidepressant agent 8 (Compound 1f) acts as a selective antagonist for the NMDA receptor GluN1/2A (NMDA receptorGluN1/2A), with an IC50 of 2.94 μmol/L. In a hydrocortisone-induced zebrafish depression model, it demonstrates antidepressant-like effects and shows good blood-brain barrier penetration.</p>
    Fórmula:C18H23FN4OS2
    Cor e Forma:Solid
    Peso molecular:394.53

    Ref: TM-T205232

  • LY503430
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    LY503430

    CAS:
    <p>LY503430: Oral AMPA enhancer with nootropic, neuroprotective properties, mitigates 6-OHDA/MPTP brain damage.</p>
    Fórmula:C20H25FN2O3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:392.49

    Ref: TM-T27959

  • Logotipo do CymitQuimica
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    Antimalarial agent 7

    <p>Antimalarial agent 7 is a potent and effective inhibitor of PfATP4. Antimalarial agent 7 has potential for the study of the human plasmodium falciparum.</p>
    Fórmula:C23H22F2N4O3
    Cor e Forma:Solid
    Peso molecular:440.44

    Ref: TM-T62537

  • Olisutrigine bromide
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    Olisutrigine bromide

    CAS:
    <p>Olisutrigine bromide is a sodium channel blocker used as an analgesic.</p>
    Fórmula:C25H35BrN2
    Cor e Forma:Solid
    Peso molecular:443.463

    Ref: TM-T205479

  • ErSO-TFPy
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    ErSO-TFPy

    CAS:
    ErSO-TFPy activates the sodium ion channel TRPM4, resulting in an imbalance of intracellular calcium and sodium ions. It exhibits low nanomolar-level cytotoxicity (IC50 = 5-25 nM) by inducing necrosis in ERα+ breast cancer cell lines. Additionally, ErSO-TFPy shows antitumor activity in mouse models.
    Fórmula:C19H13F7N2O2
    Cor e Forma:Solid
    Peso molecular:434.307

    Ref: TM-T205320

  • Moxetomidate
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    Moxetomidate

    CAS:
    <p>Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.</p>
    Fórmula:C15H18N2O3
    Cor e Forma:Solid
    Peso molecular:274.315

    Ref: TM-T205308

  • LY3130481
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    LY3130481

    CAS:
    LY3130481: TARP γ-8 dependent AMPA receptor blocker; selectively targets AMPA/TARP γ-8 with 65 nM IC50.
    Fórmula:C19H18N4O3S
    Cor e Forma:Solid
    Peso molecular:382.44

    Ref: TM-T15814

  • Crinecerfont tosylate
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    Crinecerfont tosylate

    CAS:
    <p>Crinecerfont tosylate is an effective oral CRF1 receptor antagonist. It is applicable to studies involving congenital adrenal hyperplasia (CAH).</p>
    Fórmula:C34H36ClFN2O4S2
    Cor e Forma:Solid
    Peso molecular:655.242

    Ref: TM-T205414

  • (3S,6R)-NML
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    (3S,6R)-NML

    CAS:
    <p>(3S,6R)-NML is an NMDA receptor antagonist with pIC50 values of 4.8 [GluN1-GluN2A], 4.6 [GluN1-GluN2B], 5.0 [GluN1-GluN2C], and 5.0 [GluN1-GluN2D]. It is applicable in the study of depression.</p>
    Fórmula:C20H27NO
    Cor e Forma:Solid
    Peso molecular:297.435

    Ref: TM-T205321

  • PDE2 inhibitor 6
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    PDE2 inhibitor 6

    CAS:
    <p>PDE2 inhibitor6 (Compound 1) is an orally active phosphodiesterase (PDE) inhibitor, effectively inhibiting PDE2A, PDE3B, and PDE10A2 with IC50 values of 0.95 nM, 6.17 μM (pIC50=5.21), and 87.1 nM (pIC50=7.06), respectively. It modulates AMPA receptor activity, enhances synaptic plasticity, and improves learning and memory in rat models. Furthermore, PDE2 inhibitor6 possesses blood-brain barrier permeability.</p>
    Fórmula:C20H22F2N6O
    Cor e Forma:Solid
    Peso molecular:400.425

    Ref: TM-T206498

  • TTA-P1
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    TTA-P1

    CAS:
    <p>TTA-P1: potent T-type calcium channel inhibitor; impacts neuron firing, hormone secretion, cell growth; potential in absence epilepsy research.</p>
    Fórmula:C19H27Cl2FN2O
    Cor e Forma:Solid
    Peso molecular:389.33

    Ref: TM-T61747

  • SGE-516
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    SGE-516

    CAS:
    <p>SGE516: neuroactive steroid, enhances GABAA, lowers neuronal activity, protects from seizures.</p>
    Fórmula:C23H35N3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:385.54

    Ref: TM-T28766

  • Logotipo do CymitQuimica
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    IAB15

    CAS:
    <p>IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1].</p>
    Fórmula:C15H14F3NO2
    Cor e Forma:Solid
    Peso molecular:297.27

    Ref: TM-T60648

  • Quinacainol dihydrochloride
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    Quinacainol dihydrochloride

    CAS:
    <p>Quinacainol dihydrochloride (PK 10139 dihydrochloride) is the bis(2 hydrochloride) salt form of Quinacainol. It acts as an inhibitor of the sodium current, with an EC50 of 95 µM. This compound displays antiarrhythmic activity by modulating the electrophysiological properties of the heart.</p>
    Fórmula:C21H32Cl2N2O
    Cor e Forma:Solid
    Peso molecular:399.398

    Ref: TM-T204878

  • Logotipo do CymitQuimica
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    URAT1 inhibitor 2

    <p>URAT1 inhibitor 2: oral URAT1/CYP blocker, IC50 of 1.36μM (URAT1), 16.97μM (CYP1A2), 5.22μM (CYP2C9); potential gout treatment.</p>
    Fórmula:C21H18BrN3O2S
    Cor e Forma:Solid
    Peso molecular:456.36

    Ref: TM-T62825

  • Ro-51
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    Ro-51

    CAS:
    <p>dual P2X3 and P2X2/3 antagonist</p>
    Fórmula:C17H23IN4O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:474.29

    Ref: TM-T23245

  • Logotipo do CymitQuimica
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    Cav 2.2/3.2 blocker 1

    <p>Compound 9e is a Cav 2.2/3.2 blocker; IC50: 1.22 μM &amp; 80 μM, respectively; penetrates CNS.</p>
    Fórmula:C28H30N2O3
    Cor e Forma:Solid
    Peso molecular:442.55

    Ref: TM-T62586

  • Insecticidal agent 21
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    Insecticidal agent 21

    CAS:
    <p>Insecticidal agent 21 (Compound 6) is an insecticide targeting Culex pipiens larvae with an LC50 of 0.4 μg/mL. It achieves multi-target neurotoxicity by inhibiting acetylcholinesterase (AChE) and simultaneously targeting other neural receptors, including nicotinic acetylcholine receptors (nAChR), voltage-gated sodium channels (VGSC), and γ-aminobutyric acid receptors (GABAAR). Insecticidal agent 21 shows potent insecticidal activity and can be utilized in the development of new insecticides to combat mosquito resistance to conventional agents.</p>
    Fórmula:C37H40ClN3O2
    Cor e Forma:Solid
    Peso molecular:594.185

    Ref: TM-T206704

  • ATPase-IN-5
    Targetmol
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    ATPase-IN-5

    CAS:
    <p>ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.</p>
    Fórmula:C10H10N4O3S
    Pureza:99.19%
    Cor e Forma:Solid
    Peso molecular:266.28

    Ref: TM-T204943