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Transportador de Membranas/Canal Iónico

Transportador de Membranas/Canal Iónico

Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.

Subcategorias de "Transportador de Membranas/Canal Iónico"

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Foram encontrados 2290 produtos de "Transportador de Membranas/Canal Iónico"

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  • Logotipo do CymitQuimica
    Targetmol
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    P-gp modulator 3

    <p>P-gp modulator 3 (Compound 37) is a potent, competitive, metabotropic P-glycoprotein (P-gp) modulator.</p>
    Fórmula:C31H37N3O5
    Cor e Forma:Solid
    Peso molecular:531.64

    Ref: TM-T63745

  • (R)-Duloxetine
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    (R)-Duloxetine

    CAS:
    <p>(R)-Duloxetine, an isomer of Duloxetine, induces tonic and use-dependent blockade of neuronal Na+ channels. This compound is utilized in pain research.</p>
    Fórmula:C18H19NOS
    Cor e Forma:Solid
    Peso molecular:297.42

    Ref: TM-T200895

  • Opakalim
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    Opakalim

    CAS:
    <p>Opakalim is an activator of potassium channels (potassium channel) and exhibits anticonvulsant activity.</p>
    Fórmula:C18H22F2N4O
    Cor e Forma:Solid
    Peso molecular:348.39

    Ref: TM-T206117

  • P-gp modulator 1
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    P-gp modulator 1

    CAS:
    <p>P-gp modulator 1 is a high affinity and orally available P-glycoprotein (Pgp) modulator</p>
    Fórmula:C41H72N2O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:689.02

    Ref: TM-T12340

  • Logotipo do CymitQuimica
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    Cav 3.2 inhibitor 3

    <p>Cav 3.2 inhibitor 3 is a potent inhibitor of the Cav3.2 T-type Ca2+channel (IC50: 0.1534 μM) and has a low binding affinity for D2 receptors.</p>
    Fórmula:C32H37N3O2
    Cor e Forma:Solid
    Peso molecular:495.66

    Ref: TM-T63350

  • KPH2f
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    KPH2f

    CAS:
    <p>KPH2f: dual URAT1/GLUT9 inhibitor, orally active, IC50: 0.24μM (URAT1), 9.37μM (GLUT9), minimal OAT1/ABCG2 impact.</p>
    Fórmula:C24H16N3NaO2S
    Cor e Forma:Solid
    Peso molecular:433.46

    Ref: TM-T62432

  • DS88790512
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    DS88790512

    CAS:
    <p>DS88790512, IC50 at 11 nM, is an effective, selective, oral bioeffective TRPC6 inhibitor.</p>
    Fórmula:C22H29N3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:367.48

    Ref: TM-T11105

  • 4α-PDD
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    4α-PDD

    CAS:
    <p>4alpha-PDD activates transient receptor potential vanilloid 4 (TRPV4) channels and is inactive for signaling through PKC.</p>
    Fórmula:C40H64O8
    Cor e Forma:Solid
    Peso molecular:672.93

    Ref: TM-T26386

  • Onfasprodil
    Targetmol
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    Onfasprodil

    CAS:
    <p>Onfasprodil, NR2B inhibitor &amp; GABA regulator, potential for Alzheimer's research. (Patent CN111481543A)</p>
    Fórmula:C20H23FN2O3
    Cor e Forma:Solid
    Peso molecular:358.41

    Ref: TM-T61319

  • Valbenazine tosylate
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    Valbenazine tosylate

    CAS:
    <p>Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no</p>
    Fórmula:C38H54N2O10S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:762.97

    Ref: TM-T22452

  • Logotipo do CymitQuimica
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    WS-898

    <p>WS-898 boosts paclitaxel efficacy in resistant cells by inhibiting ABCB1; IC50: SW620/Ad300 - 5.0 nM, KB-C2 - 3.67 nM, HEK293/ABCB1 - 3.68 nM.</p>
    Fórmula:C33H25N7OS
    Cor e Forma:Solid
    Peso molecular:567.66

    Ref: TM-T64016

  • (RS)-AMPA
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    (RS)-AMPA

    CAS:
    <p>(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.</p>
    Fórmula:C7H10N2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:186.17

    Ref: TM-T16800

  • NYX-2925
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    NYX-2925

    CAS:
    <p>NYX-2925, an oral NMDAR modulator, enhances Src in mPFC. No CAMKII impact or addictive/sedative effects. Useful for CNS disorder studies.</p>
    Fórmula:C14H23N3O4
    Cor e Forma:Solid
    Peso molecular:297.35

    Ref: TM-T73359

  • Ro 0437626
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    Ro 0437626

    CAS:
    <p>P2X1 purinergic receptor antagonist</p>
    Fórmula:C27H35N5O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:525.66

    Ref: TM-T23241

  • Logotipo do CymitQuimica
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    TRPV1 antagonist 3

    <p>TRPV1 antagonist 3 (7q) strongly blocks TRPV1 at 2.66 nM IC50, is selective, 60% bioavailable, and crosses the blood-brain barrier.</p>
    Fórmula:C23H25N3OS
    Cor e Forma:Solid
    Peso molecular:391.53

    Ref: TM-T61788

  • Logotipo do CymitQuimica
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    KCa2 channel modulator 2

    Compound 2q is a potent, subtype-selective K/Ca 2 modulator, effective on human K Ca 2.3 and rat K Ca 2.2a with EC50s of 0.60 μM and 0.64 μM.
    Fórmula:C16H15ClFN5
    Cor e Forma:Solid
    Peso molecular:331.78

    Ref: TM-T60986

  • Logotipo do CymitQuimica
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    DFBTA

    <p>DFBTA inhibits ANO1 with IC50 of 24 nM, effectively treating inflammatory pain orally.</p>
    Fórmula:C18H10ClF2NO3S
    Cor e Forma:Solid
    Peso molecular:393.79

    Ref: TM-T61818

  • Blixeprodil
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    Blixeprodil

    CAS:
    <p>Blixeprodil (GM-1020) is an orally active NMDA receptor antagonist with an affinity of Ki = 3.25 µM in rat cortical tissue. It inhibits NR1/2A-NMDAR-mediated currents in HEK293 cells with an IC50 of 1.192 µM. Blixeprodil demonstrates antidepressant effects in rat models and exhibits blood-brain barrier permeability.</p>
    Fórmula:C13H16FNO
    Cor e Forma:Solid
    Peso molecular:221.271

    Ref: TM-T206599

  • ABCG2-IN-4
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    ABCG2-IN-4

    CAS:
    <p>ABCG2-IN-4 (Compound K31) is an orally active ABCG2 inhibitor that reduces the release of Protoporphyrin IX (PPIX) from red blood cells into the plasma and prevents phototoxicity. In mouse models, ABCG2-IN-4 also demonstrates anti-inflammatory and antioxidant properties.</p>
    Fórmula:C24H32N4O4
    Cor e Forma:Solid
    Peso molecular:440.535

    Ref: TM-T204144

  • Coleon-U-quinone
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    Coleon-U-quinone

    CAS:
    <p>Coleon-U-quinone, a P-gp inhibitor, reduces cancer cell viability and enhances Doxorubicin sensitivity in resistant cells.</p>
    Fórmula:C20H24O5
    Cor e Forma:Solid
    Peso molecular:344.4

    Ref: TM-T72735