Transportador de Membranas/Canal Iónico
Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.
Subcategorias de "Transportador de Membranas/Canal Iónico"
- ABC(3 produtos)
- ATPase(98 produtos)
- Receptor de adiponectina(5 produtos)
- CFTR(66 produtos)
- Receptor CGRP(53 produtos)
- Canais de Cálcio(525 produtos)
- Canal de cloreto(51 produtos)
- Receptor GABA(355 produtos)
- Transportador de monoamina(26 produtos)
- Transportador de monocarboxilato(18 produtos)
- NKCC(2 produtos)
- NPC1L1(3 produtos)
- Cotransportador Na-K-Cl(9 produtos)
- OAT(28 produtos)
- OCT(7 produtos)
- P-gp(52 produtos)
- Canal de Potássio(280 produtos)
- Bomba de prótons(40 produtos)
- SGLT(31 produtos)
- Canal de Sódio(202 produtos)
- Canal TRP/TRPV(94 produtos)
Exibir 13 mais subcategorias
Foram encontrados 2430 produtos de "Transportador de Membranas/Canal Iónico"
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Dehydroindapamide
CAS:Dehydroindapamide, an indole form of Indapamide, is utilized to quantify the turnover rate of Indapamide in CYP3A4, which is approximately 10 times higher than that of Indoline, with slightly enhanced affinity for CYP3A4.Fórmula:C16H14ClN3O3SCor e Forma:SolidPeso molecular:363.82Refisolone
CAS:Refisolone is an antagonist of the GABAA receptor.Fórmula:C18H24O3Peso molecular:288.381Lubeluzole dihydrochloride
CAS:<p>Lubeluzole (dihydrochloride) acts as a neuroprotective agent by blocking neuronal voltage-gated sodium channels and also affects cardiac sodium channels, exhibiting both tonic and blocking effects. This compound is considered promising in the research of antiarrhythmic agents.</p>Fórmula:C22H27Cl2F2N3O2SCor e Forma:SolidPeso molecular:506.44Perfluoroheptanesulfonic acid
CAS:Perfluoroheptanesulfonic acid (1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid) is a perfluoroalkyl substance (PFAS). This compound has been detected in landfill leachate and has been shown to induce deformities in zebrafish larvae (EC50=168.1 μM). Exposure to PFHpS in fetuses can lead to reduced birth weight.Fórmula:C7HF15O3SCor e Forma:SolidPeso molecular:450.12Lafadofensine (D-(-)-Mandelic acid)
Lafadofensine D-(-)-Mandelic acid is a monoamines reuptake inhibitor with adequate effects when administered short-term.Fórmula:C32H32F2N2O6Cor e Forma:SolidPeso molecular:578.6Kv7.2/Kv7.3 activator-1
CAS:<p>Kv7.2/Kv7.3 Activator-1 (compound 517) serves as a powerful activator of the Kv7.2/Kv7.3 channels, exhibiting an EC50 value of less than 1 µM. It holds potential for use in neurological disease research.</p>Fórmula:C19H22F2N4OCor e Forma:SolidPeso molecular:360.40PF-05661014
CAS:<p>PF-05661014, a demethylated analogue of PF-06526290, selectively inhibits Nav1.3 and Nav1.7 currents by stabilizing the inactivated state through interaction with the D4 VSD. This compound is utilized in research focused on sodium channel modulation.</p>Fórmula:C17H16N4O3S2Cor e Forma:SolidPeso molecular:388.46CFTR corrector 16
CAS:<p>CFTRcorrector 16 (Compound 39) is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR), utilized in the research of cystic fibrosis disease.</p>Fórmula:C27H26ClN5O2SCor e Forma:SolidPeso molecular:520.05SP100030 analogue 1
CAS:SP100030 analogue 1 (compound 11) is a selective transcription activation (SITA) inhibitor within the SP100030 class, capable of inhibiting XPO1-dependent upregulation of IL2 in a Jurkat-based IL2-Luc reporter assay, with an EC50 of 137 nM.Fórmula:C13H5ClF7N3OCor e Forma:SolidPeso molecular:387.64(+)-Tetrabenazine
CAS:(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-foldFórmula:C19H27NO3Pureza:98.69%Cor e Forma:SolidPeso molecular:317.42Odevixibat
CAS:Odevixibat (A4250) is a selective oral inhibitor for ileal bile acid transport, potentially treating primary biliary cirrhosis.Fórmula:C37H48N4O8S2Pureza:99.53% - 99.83%Cor e Forma:SolidPeso molecular:740.93SDZ 220-040
CAS:<p>SDZ 220-040 是一种选择性哺乳动物 NMDA 受体拮抗剂，可诱导根系生长的部分无重力模式 。</p>Fórmula:C16H16Cl2NO6PPureza:98.13%Cor e Forma:SolidPeso molecular:420.18Suzetrigine
CAS:Suzetrigine (VX-548) is an oral NaV1.8 inhibitor with analgesic properties for acute pain research.Fórmula:C21H20F5N3O4Pureza:98.08% - 99.27%Cor e Forma:SolidPeso molecular:473.39SYM2206
CAS:<p>SYM2206 is a low affinity non-competitive AMPA receptor antagonist with an IC50 value of 1.6 μM.SYM2206 exhibits anticancer activity by blocking Nav1.6-mediated</p>Fórmula:C20H22N4O3Pureza:99.88%Cor e Forma:SolidPeso molecular:366.415-Hydroxylansoprazole
CAS:5-Hydroxylansoprazole (AG1908) is the active metabolite of plasma Lansoprazole, inhibits the proton pump, and is used in the study of peptic ulcers.Fórmula:C16H14F3N3O3SPureza:99.00%Cor e Forma:SolidPeso molecular:385.36A-887826
CAS:A-887826 is a selective, orally bioavailable, and voltage-dependent Na(v1.8) channel blocker (IC50: 11 nM). It attenuates neuropathic tactile allodynia in vivo.Fórmula:C26H29ClN4O3Cor e Forma:SolidPeso molecular:480.99(-)-Bicuculline methobromide
CAS:(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .Fórmula:C21H20BrNO6Cor e Forma:WhitePeso molecular:462.29Umbellulone
CAS:Umbellulone is a natural product isolated from Umbellularia californica, and stimulates the TRPA1 channel in a subset of peptidergic, nociceptive neurons, activating the trigeminovascular system via this mechanism.Fórmula:C10H14OPureza:98%Cor e Forma:SolidPeso molecular:150.22(Rac)-Lanicemine
CAS:<p>(Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker with a Ki of 0.56-2.1 μM for the NMDA receptor and IC50 values of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively. Lanicemine shows antidepressant effects [1].</p>Fórmula:C13H14N2Cor e Forma:SolidPeso molecular:198.26L-Cysteine S-sulfate sodium salt sesquihydrate
CAS:L-Cysteine S-sulfate sodium salt sesquihydrate is a useful organic compound for research related to life sciences. The catalog number is T64782 and the CAS number is 150465-29-5.Fórmula:C9H25N3Na3O17S6Cor e Forma:SolidPeso molecular:708.63
