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Transportador de Membranas/Canal Iónico

Transportador de Membranas/Canal Iónico

Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.

Subcategorias de "Transportador de Membranas/Canal Iónico"

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Foram encontrados 2280 produtos de "Transportador de Membranas/Canal Iónico"

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  • Foslevcromakalim
    Targetmol
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    Foslevcromakalim

    CAS:
    <p>Foslevcromakalim (QLS-101), an ATP-sensitive potassium channel opener, serves as a proagent for ocular hypotensive effects [1] [2].</p>
    Fórmula:C16H19N2O6P
    Cor e Forma:Solid
    Peso molecular:366.31

    Ref: TM-T75084

  • Logotipo do CymitQuimica
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    Antidepressant agent 3

    <p>Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.</p>
    Fórmula:C17H30ClN5O2S
    Cor e Forma:Solid
    Peso molecular:403.97

    Ref: TM-T75002

  • Mambalgin 1
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    Mambalgin 1

    CAS:
    <p>ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.</p>
    Fórmula:C272H429N85O84S10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:6554.51

    Ref: TM-TP2003

  • ProTx-I
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    ProTx-I

    CAS:
    <p>Selective blocker for CaV3.1 (IC50 = 0.2 μM), CaV3.2 (31.8 μM), also inhibits NaV1.8 and blocks KV2.1 channels.</p>
    Fórmula:C171H245N53O47S6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3987.51

    Ref: TM-TP1968

  • N-Oleoyl Glutamine
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    N-Oleoyl Glutamine

    CAS:
    <p>N-Oleoyl Glutamine (Oleoyl-L-glutamine) antagonizes TRPV1 of the transient receptor potential (TRP) calcium channel.</p>
    Fórmula:C23H42N2O4
    Pureza:99.61%
    Cor e Forma:Solid
    Peso molecular:410.59

    Ref: TM-T36064

  • 5-Hydroxy-2′,3,4′,7-tetramethoxyflavone
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    5-Hydroxy-2′,3,4′,7-tetramethoxyflavone

    CAS:
    <p>5-Hydroxy-2′,3,4′,7-tetramethoxyflavone shows weak ABCG2 inhibitory potency with IC50s of 3.27 and 3.89 µM in the Hoechst 33342 and pheophorbide A assays.</p>
    Fórmula:C19H18O7
    Pureza:98%
    Cor e Forma:Soild
    Peso molecular:358.34

    Ref: TM-TN7124

  • (±)17-HETE
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    (±)17-HETE

    CAS:
    <p>Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.</p>
    Fórmula:C20H32O3
    Cor e Forma:Solid
    Peso molecular:320.473

    Ref: TM-T35523

  • RuBi-GABA
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    RuBi-GABA

    CAS:
    <p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>
    Fórmula:C42H39F6N5O2P2Ru
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:922.8

    Ref: TM-T23277

  • Logotipo do CymitQuimica
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    Kurtoxin

    <p>Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type)</p>
    Fórmula:C324H478N94O90S8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:7386.36

    Ref: TM-T80496

  • GSK2332255B
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    GSK2332255B

    CAS:
    <p>GSK2332255B: potent TRPC3/6 antagonist; IC50 5 nM (TRPC3), 4 nM (TRPC6); over 100-fold selectivity vs other Ca2+ channels.</p>
    Fórmula:C18H19ClFN3O3S
    Cor e Forma:Solid
    Peso molecular:411.88

    Ref: TM-T38780

  • Logotipo do CymitQuimica
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    HG1 Toxin

    <p>HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, known for its ability to inhibit the potassium channel Kv1.3 (potassium channel Kv1.3). Additionally, HG1 Toxin exhibits trypsin inhibitory activity (Ki=107 nM), making it useful for research into autoimmune diseases.</p>
    Fórmula:C337H503N103O97S6
    Peso molecular:7736.59176

    Ref: TM-TP3643

  • Logotipo do CymitQuimica
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    L-Palmitoylcarnitine TFA

    <p>L-Palmitoylcarnitine TFA: long-chain fat metabolite that disrupts membranes in ischaemia &amp; inhibits KATP channels via Kir6.2 interaction.</p>
    Fórmula:C25H46F3NO6
    Cor e Forma:Solid
    Peso molecular:513.63

    Ref: TM-T73764

  • Ziconotide
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    Ziconotide

    CAS:
    <p>Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.</p>
    Fórmula:C102H172N36O32S7
    Pureza:98%
    Cor e Forma:White Powder
    Peso molecular:2639.13

    Ref: TM-TP1559

  • SC 4453
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    SC 4453

    CAS:
    <p>SC 4453 is a digoxin analog and a cardiac glycoside derivative.</p>
    Fórmula:C41H64N2O12
    Cor e Forma:Solid
    Peso molecular:776.965

    Ref: TM-T34554

  • APETx2
    Targetmol
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    APETx2

    CAS:
    <p>ASIC3 inhibitor; IC50: 63 nM (rat), 175 nM (human). Blocks NaV1.8, NaV1.2; analgesic for acid/inflammatory pain.</p>
    Fórmula:C196H280N54O61S6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4561.06

    Ref: TM-TP2081

  • Nav1.7-IN-8
    Targetmol
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    Nav1.7-IN-8

    CAS:
    <p>Nav1.7-IN-8 selectively inhibits NaV1.7 over hNaV1.1/1.5, affects CYP2C9/3A4 (IC50: 0.17/0.077 μM), and provides rodent pain relief.</p>
    Fórmula:C21H12ClF2N5O4S2
    Cor e Forma:Solid
    Peso molecular:535.93

    Ref: TM-T38911

  • Levamlodipine besylate Hemipentahydrate
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    Levamlodipine besylate Hemipentahydrate

    CAS:
    <p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>
    Fórmula:C20H25ClN2O5·C6H6O3SH2O
    Cor e Forma:Solid
    Peso molecular:1224.18

    Ref: TM-T204904

  • Logotipo do CymitQuimica
    Targetmol
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    ATP Synthesis-IN-2

    <p>ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.</p>
    Cor e Forma:Odour Solid

    Ref: TM-T82944

  • Logotipo do CymitQuimica
    Targetmol
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    Ebio3

    <p>Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.</p>
    Fórmula:C19H23F2N3O2
    Cor e Forma:Solid
    Peso molecular:363.4

    Ref: TM-T205242

  • Logotipo do CymitQuimica
    Targetmol
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    Anticonvulsant agent 9

    <p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>
    Fórmula:C22H24N4O2
    Cor e Forma:Solid
    Peso molecular:376.45

    Ref: TM-T205256