Transportador de Membranas/Canal Iónico

Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.

Subcategorias de "Transportador de Membranas/Canal Iónico"

Exibir 13 mais subcategorias

Foram encontrados 2290 produtos de "Transportador de Membranas/Canal Iónico"

Pureza (%)

100

produtos por página.

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Cyclic ADP-ribose ammonium
cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.
Cor e Forma:Liquid
Ref: TM-T37687
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Ion Channel Targeted Library
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
Cor e Forma:Odour Solid
Ref: TM-L2300
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(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS:
- 71830-07-4
(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.
Fórmula:C₆H₁₁NO₂
Cor e Forma:Solid
Peso molecular:129.16
Ref: TM-T203289
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Volixibat
CAS:
- 1025216-57-2
Volixibat, a selective inhibitor of the bile acid transporter, may treat non-alcoholic steatohepatitis.
Fórmula:C₃₈H₅₁N₃O₁₂S₂
Pureza:98%
Cor e Forma:Solid
Peso molecular:805.95
Ref: TM-T17236
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CALP3
CAS:
- 261969-05-5
Cell-permeable CaM agonist, binds EF-hand, activates phosphodiesterase without Ca2+, inhibits Ca2+ toxicity, IC50=33μM.
Fórmula:C₄₄H₆₈N₁₀O₉
Pureza:98%
Cor e Forma:Solid
Peso molecular:881.08
Ref: TM-TP1911
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Homocarnosine TFA
Homocarnosine TFA: brain-exclusive GABA-histidine dipeptide, neuronal, anticonvulsant, antioxidant, anti-inflammatory.
Fórmula:C₁₂H₁₇F₃N₄O₅
Cor e Forma:Solid
Peso molecular:354.28
Ref: TM-T73818
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Withasomniferolide B
CAS:
- 2365386-75-8
Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.
Fórmula:C₂₈H₃₆O₄
Cor e Forma:Solid
Peso molecular:436.58
Ref: TM-T75557
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GeX-2
CAS:
- 2900996-95-2
GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.
Fórmula:C₁₀₃H₁₆₉N₄₃O₂₇
Cor e Forma:Solid
Peso molecular:2441.72
Ref: TM-TP3132
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(±)8(9)-EpETE
CAS:
- 851378-93-3
(±)8(9)-EpETE ((±)8,9-EEQ) is an epoxide of arachidonic acid biosynthesized by CYP450 epoxygenase.1.2 In rat and rabbit liver microsomes.
Fórmula:C₂₀H₃₀O₃
Cor e Forma:Solid
Peso molecular:318.45
Ref: TM-T37228
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ShK-Dap22
CAS:
- 220384-25-8
Potent KV1.3 channel blocker; Kd 23 pM; selective; inhibits T cell activation; IC50 < 500 pM for mKV1.3.
Fórmula:C₁₆₆H₂₆₈N₅₄O₄₈S₇
Pureza:98%
Cor e Forma:Solid
Peso molecular:4012.7
Ref: TM-TP2123
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Albanin A
Albanin A is a useful organic compound for research related to life sciences and the catalog number is T124310.
Fórmula:C₂₀H₁₈O₆
Cor e Forma:Solid
Peso molecular:354.358
Ref: TM-T124310
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ML353
ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.
Fórmula:C₁₉H₁₅FN₂O
Pureza:99.98% - 99.98%
Cor e Forma:Soild
Peso molecular:306.33
Ref: TM-T67917
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Sinapine hydroxide
CAS:
- 122-30-5
Sinapine hydroxide from crucifer seeds has anti-inflammatory, anti-oxidant, anti-tumor properties, and inhibits AChE, aiding neurodegenerative research.
Fórmula:C₁₆H₂₅NO₆
Cor e Forma:Solid
Peso molecular:327.377
Ref: TM-T38606
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Guangxitoxin 1E
CAS:
- 1233152-82-3
Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.
Fórmula:C₁₇₈H₂₄₈N₄₄O₄₅S₇
Pureza:98%
Cor e Forma:Solid
Peso molecular:3948.61
Ref: TM-TP1531
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Conantokin G TFA
Conantokin G TFA, a 17-aa peptide, blocks NMDA receptors with 480 nM IC50 and is neuroprotective.
Fórmula:C₉₀H₁₃₉F₃N₂₆O₄₆
Cor e Forma:Solid
Peso molecular:2378.21
Ref: TM-T75890
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AR-C141990 hydrochloride
CAS:
- 2250019-94-2
AR-C141990 HCl inhibits MCT-1 (pKi 7.6) and MCT-2 (pKi 6.6), and has immunosuppressive effects.
Fórmula:C₂₆H₂₉ClN₄O₄S
Cor e Forma:Solid
Peso molecular:529.05
Ref: TM-T39767
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Nitrazolam
CAS:
- 28910-99-8
Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.
Fórmula:C₁₇H₁₃N₅O₂
Cor e Forma:Solid
Peso molecular:319.32
Ref: TM-T203627
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Digoxigenin Monodigitoxoside
CAS:
- 5352-63-6
Digoxigenin monodigitoxoside is a cardiac glycoside metabolite of digoxin and a Na+/K+ ATPase inhibitor.
Fórmula:C₂₉H₄₄O₈
Cor e Forma:Solid
Peso molecular:520.663
Ref: TM-T36060
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CBP-1008
CBP-1008 is a dual-ligand peptide-drug conjugate (PDC) with MMAE, targeting folate receptor (FRα) and TRPV6. It exhibits high binding affinity to FRα and low affinity to TRPV6. CBP-1008 shows antitumor activity and can be utilized for research in advanced solid tumors such as colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma, and follicular dendritic cell sarcoma.
Cor e Forma:Odour Solid
Ref: TM-TP2953
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(R)-IDHP
CAS:
- 950665-05-1
(R)-IDHP, a salvia derivative, relaxes blood vessels by blocking calcium channels, aiding cardiovascular research.
Fórmula:C₁₂H₁₆O₅
Cor e Forma:Solid
Peso molecular:240.25
Ref: TM-T74193