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Transportador de Membranas/Canal Iónico

Transportador de Membranas/Canal Iónico

Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.

Subcategorias de "Transportador de Membranas/Canal Iónico"

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Foram encontrados 2293 produtos de "Transportador de Membranas/Canal Iónico"

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  • Logotipo do CymitQuimica
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    Anticonvulsant agent 8

    <p>Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.</p>
    Fórmula:C15H11N5O
    Cor e Forma:Solid
    Peso molecular:277.28

    Ref: TM-T205302

  • BeKm-1
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    BeKm-1

    CAS:
    <p>Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.</p>
    Fórmula:C174H261N51O52S6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4091.65

    Ref: TM-TP2072

  • Phe-Met-Arg-Phe, amide
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    Phe-Met-Arg-Phe, amide

    CAS:
    Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.
    Fórmula:C29H42N8O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:598.76

    Ref: TM-TP1858

  • DAA-1106
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    DAA-1106

    CAS:
    <p>DAA-1106 is a potent and selective ligand for PBR, acting as a potent and selective agonist at the peripheral benzodiazepine receptor.</p>
    Fórmula:C23H22FNO4
    Pureza:99.54%
    Cor e Forma:Solid
    Peso molecular:395.42

    Ref: TM-T3173

  • AQP4 (205-215)
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    AQP4 (205-215)

    CAS:
    <p>AQP4 (205-215) is a fragment of the water channel protein Aquaporin-4 (AQP4). This protein is an autoimmune antigen in optic neuromyelitis and, upon binding with CD40, is upregulated and presented in B cells. AQP4 is associated with neuromyelitis optica (NMO), an autoimmune inflammatory disease of the central nervous system (CNS).</p>
    Fórmula:C48H75N13O17S
    Cor e Forma:Solid
    Peso molecular:1138.25

    Ref: TM-TP3218

  • Fumitremorgin C
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    Fumitremorgin C

    CAS:
    <p>Fumitremorgin C (12α-Fumitremorgin C) is a mycotoxin and inhibits ABCG2/BRCP.</p>
    Fórmula:C22H25N3O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:379.45

    Ref: TM-T15355

  • Logotipo do CymitQuimica
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    P-gp inhibitor 13

    <p>P-gp Inhibitor 13, a P-glycoprotein antagonist, can counteract paclitaxel resistance in A2780/T cells, proving valuable for advanced acute myeloid leukemia</p>
    Fórmula:C32H34O8
    Cor e Forma:Solid
    Peso molecular:546.61

    Ref: TM-T78974

  • Elgodipine
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    Elgodipine

    CAS:
    <p>Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.</p>
    Fórmula:C29H33FN2O6
    Pureza:98.95% - 99.50%
    Cor e Forma:Solid
    Peso molecular:524.58

    Ref: TM-T68060

  • Ouabagenin
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    Ouabagenin

    CAS:
    <p>Ouabagenin, a naturally occurring LXR ligand with selective agonist activity, functions as an EC 3.6.3.9 (Na(+)/K(+)-transport ATPase) inhibitor [1] [2].</p>
    Fórmula:C23H34O8
    Cor e Forma:Solid
    Peso molecular:438.51

    Ref: TM-TN7752

  • Milbemycin A4
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    Milbemycin A4

    CAS:
    <p>Milbemycin A4, a distinguished member of the macrocyclic lactones family featuring a unique spiroketal group, is derived from the fermentation of the soil bacterium Streptomyces hygroscopicus subsp. aureolacrimosus. It acts by enhancing the opening of glutamate and GABA-gated chloride channels, rendering it effective as both a nematocide and insecticide.</p>
    Fórmula:C32H46O7
    Cor e Forma:Solid
    Peso molecular:542.713

    Ref: TM-TN7268

  • Logotipo do CymitQuimica
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    H-Lys-Tyr-OH TFA

    <p>Lysyltyrosine TFA is a dipeptide that may enhance brain function by boosting noradrenaline and tyrosine release.</p>
    Fórmula:C17H24F3N3O6
    Cor e Forma:Solid
    Peso molecular:423.38

    Ref: TM-T74045

  • TRPV4 antagonist 4
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    TRPV4 antagonist 4

    CAS:
    <p>Potent TRPV4 blocker with 22.65 nM IC50; inhibits current and aids acute lung injury.</p>
    Fórmula:C28H32Cl2N6O
    Cor e Forma:Solid
    Peso molecular:539.50

    Ref: TM-T74832

  • Logotipo do CymitQuimica
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    Analgesic/antidepressant agent-1

    <p>Analgesic/antidepressant agent-1 (Compound k1) is an orally active N-acetylamino chloro ketone derivative capable of crossing the blood-brain barrier. It exhibits high affinity for NMDA receptors and demonstrates analgesic, anti-inflammatory, and antidepressant properties, with low psychotomimetic activity.</p>
    Fórmula:C22H25ClN2O2
    Cor e Forma:Solid
    Peso molecular:384.9

    Ref: TM-T205604

  • TRPV4 antagonist 3
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    TRPV4 antagonist 3

    CAS:
    <p>TRPV4 antagonist 3 is a TRPV4 antagonist (p IC 50 = 8.4).</p>
    Fórmula:C20H18F4N4O3S
    Cor e Forma:Solid
    Peso molecular:470.44

    Ref: TM-T40306

  • (R)-AMPA
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    (R)-AMPA

    CAS:
    <p>inactive enantiomer of AMPA</p>
    Fórmula:C7H10N2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:186.17

    Ref: TM-T23220

  • Vanzacaftor
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    Vanzacaftor

    CAS:
    <p>Vanzacaftor is a CFTR modulator improving protein processing and surface trafficking, restoring chloride transport and aiding cystic fibrosis therapy research.</p>
    Fórmula:C32H39N7O4S
    Pureza:99.14%
    Cor e Forma:Solid
    Peso molecular:617.76

    Ref: TM-T74417

  • TRPV1 activator-2
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    TRPV1 activator-2

    CAS:
    <p>TRPV1 activator-2 (Compound 9), a capsaicin head analog, engages in targeted interactions with channel residues at the lipid-water interface [1].</p>
    Fórmula:C19H29NO3
    Cor e Forma:Solid
    Peso molecular:319.44

    Ref: TM-T74742

  • Logotipo do CymitQuimica
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    Tertiapin LQ

    <p>Kir1.1 channel blocker, 250x selective; Kd: Kir1.1 (1.1 nM), Kir3.1/3.2 (274 nM), Kir3.1/3.4 (361 nM). Tertiapin-Q derivative.</p>
    Fórmula:C106H179N33O24S4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2428.03

    Ref: TM-TP2113

  • GX 201
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    GX 201

    CAS:
    <p>GX 201 is a selective NaV1.7 inhibitor, IC50 of &lt; 3.2 nM for hNaV1.7.</p>
    Fórmula:C25H27ClF4N2O4S
    Pureza:99.81%
    Cor e Forma:Solid
    Peso molecular:563

    Ref: TM-T9647

  • Agitoxin-2
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    Agitoxin-2

    CAS:
    Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).
    Fórmula:C169H278N54O48S8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4090.87

    Ref: TM-TP2089