Transportador de Membranas/Canal Iónico
Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.
Subcategorias de "Transportador de Membranas/Canal Iónico"
- ABC(3 produtos)
- ATPase(93 produtos)
- Receptor de adiponectina(5 produtos)
- CFTR(64 produtos)
- Receptor CGRP(52 produtos)
- Canais de Cálcio(496 produtos)
- Canal de cloreto(49 produtos)
- Receptor GABA(336 produtos)
- Transportador de monoamina(23 produtos)
- Transportador de monocarboxilato(17 produtos)
- NKCC(2 produtos)
- NPC1L1(3 produtos)
- Cotransportador Na-K-Cl(8 produtos)
- OAT(27 produtos)
- OCT(7 produtos)
- P-gp(53 produtos)
- Canal de Potássio(277 produtos)
- Bomba de prótons(39 produtos)
- SGLT(30 produtos)
- Canal de Sódio(202 produtos)
- Canal TRP/TRPV(93 produtos)
Exibir 13 mais subcategorias
Foram encontrados 2290 produtos de "Transportador de Membranas/Canal Iónico"
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P-gp modulator 3
<p>P-gp modulator 3 (Compound 37) is a potent, competitive, metabotropic P-glycoprotein (P-gp) modulator.</p>Fórmula:C31H37N3O5Cor e Forma:SolidPeso molecular:531.64(R)-Duloxetine
CAS:<p>(R)-Duloxetine, an isomer of Duloxetine, induces tonic and use-dependent blockade of neuronal Na+ channels. This compound is utilized in pain research.</p>Fórmula:C18H19NOSCor e Forma:SolidPeso molecular:297.42Opakalim
CAS:<p>Opakalim is an activator of potassium channels (potassium channel) and exhibits anticonvulsant activity.</p>Fórmula:C18H22F2N4OCor e Forma:SolidPeso molecular:348.39P-gp modulator 1
CAS:<p>P-gp modulator 1 is a high affinity and orally available P-glycoprotein (Pgp) modulator</p>Fórmula:C41H72N2O6Pureza:98%Cor e Forma:SolidPeso molecular:689.02Cav 3.2 inhibitor 3
<p>Cav 3.2 inhibitor 3 is a potent inhibitor of the Cav3.2 T-type Ca2+channel (IC50: 0.1534 μM) and has a low binding affinity for D2 receptors.</p>Fórmula:C32H37N3O2Cor e Forma:SolidPeso molecular:495.66KPH2f
CAS:<p>KPH2f: dual URAT1/GLUT9 inhibitor, orally active, IC50: 0.24μM (URAT1), 9.37μM (GLUT9), minimal OAT1/ABCG2 impact.</p>Fórmula:C24H16N3NaO2SCor e Forma:SolidPeso molecular:433.46DS88790512
CAS:<p>DS88790512, IC50 at 11 nM, is an effective, selective, oral bioeffective TRPC6 inhibitor.</p>Fórmula:C22H29N3O2Pureza:98%Cor e Forma:SolidPeso molecular:367.484α-PDD
CAS:<p>4alpha-PDD activates transient receptor potential vanilloid 4 (TRPV4) channels and is inactive for signaling through PKC.</p>Fórmula:C40H64O8Cor e Forma:SolidPeso molecular:672.93Onfasprodil
CAS:<p>Onfasprodil, NR2B inhibitor & GABA regulator, potential for Alzheimer's research. (Patent CN111481543A)</p>Fórmula:C20H23FN2O3Cor e Forma:SolidPeso molecular:358.41Valbenazine tosylate
CAS:<p>Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no</p>Fórmula:C38H54N2O10S2Pureza:98%Cor e Forma:SolidPeso molecular:762.97WS-898
<p>WS-898 boosts paclitaxel efficacy in resistant cells by inhibiting ABCB1; IC50: SW620/Ad300 - 5.0 nM, KB-C2 - 3.67 nM, HEK293/ABCB1 - 3.68 nM.</p>Fórmula:C33H25N7OSCor e Forma:SolidPeso molecular:567.66(RS)-AMPA
CAS:<p>(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.</p>Fórmula:C7H10N2O4Pureza:98%Cor e Forma:SolidPeso molecular:186.17NYX-2925
CAS:<p>NYX-2925, an oral NMDAR modulator, enhances Src in mPFC. No CAMKII impact or addictive/sedative effects. Useful for CNS disorder studies.</p>Fórmula:C14H23N3O4Cor e Forma:SolidPeso molecular:297.35Ro 0437626
CAS:<p>P2X1 purinergic receptor antagonist</p>Fórmula:C27H35N5O4SPureza:98%Cor e Forma:SolidPeso molecular:525.66TRPV1 antagonist 3
<p>TRPV1 antagonist 3 (7q) strongly blocks TRPV1 at 2.66 nM IC50, is selective, 60% bioavailable, and crosses the blood-brain barrier.</p>Fórmula:C23H25N3OSCor e Forma:SolidPeso molecular:391.53KCa2 channel modulator 2
Compound 2q is a potent, subtype-selective K/Ca 2 modulator, effective on human K Ca 2.3 and rat K Ca 2.2a with EC50s of 0.60 μM and 0.64 μM.Fórmula:C16H15ClFN5Cor e Forma:SolidPeso molecular:331.78DFBTA
<p>DFBTA inhibits ANO1 with IC50 of 24 nM, effectively treating inflammatory pain orally.</p>Fórmula:C18H10ClF2NO3SCor e Forma:SolidPeso molecular:393.79Blixeprodil
CAS:<p>Blixeprodil (GM-1020) is an orally active NMDA receptor antagonist with an affinity of Ki = 3.25 µM in rat cortical tissue. It inhibits NR1/2A-NMDAR-mediated currents in HEK293 cells with an IC50 of 1.192 µM. Blixeprodil demonstrates antidepressant effects in rat models and exhibits blood-brain barrier permeability.</p>Fórmula:C13H16FNOCor e Forma:SolidPeso molecular:221.271ABCG2-IN-4
CAS:<p>ABCG2-IN-4 (Compound K31) is an orally active ABCG2 inhibitor that reduces the release of Protoporphyrin IX (PPIX) from red blood cells into the plasma and prevents phototoxicity. In mouse models, ABCG2-IN-4 also demonstrates anti-inflammatory and antioxidant properties.</p>Fórmula:C24H32N4O4Cor e Forma:SolidPeso molecular:440.535Coleon-U-quinone
CAS:<p>Coleon-U-quinone, a P-gp inhibitor, reduces cancer cell viability and enhances Doxorubicin sensitivity in resistant cells.</p>Fórmula:C20H24O5Cor e Forma:SolidPeso molecular:344.4IAA65
CAS:<p>IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].</p>Fórmula:C16H13F6NO2Cor e Forma:SolidPeso molecular:365.27VU0463271 quarterhydrate
<p>VU0463271 quarterhydrate is a potent KCC2 antagonist, with an IC 50 of 61 nM [1].</p>Fórmula:C19H20N4O2S2Cor e Forma:SolidPeso molecular:387BMS-986163
CAS:<p>BMS-986163, a prodrug, quickly becomes BMS-986169, a GluN2B inhibitor (Ki=4 nM, IC50=24 nM).</p>Fórmula:C23H28FN2O5PPureza:98%Cor e Forma:SolidPeso molecular:462.45V-ATPase-IN-1
CAS:<p>V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.</p>Fórmula:C21H20ClNO2Cor e Forma:SolidPeso molecular:353.84(S)-Albuterol
CAS:<p>(S)-Albuterol functions as a muscarinic receptor and phospholipase C activator, enhancing the intracellular free calcium concentration in airway smooth muscle cells.</p>Fórmula:C13H21NO3Cor e Forma:SolidPeso molecular:239.311NMDA receptor antagonist-3
<p>NMDA antagonist-3: recovery rate 40% at 100 μM, low toxicity in SH-SY5Y, human stem cells.</p>Fórmula:C13H19N3O6Cor e Forma:SolidPeso molecular:313.31P-gp inhibitor 2
CAS:<p>Potent P-gp inhibitor 2 reverses Doxorubicin resistance in colorectal carcinoma cells with IC50 of 0.22 µM.</p>Fórmula:C29H26N2O6Cor e Forma:SolidPeso molecular:498.53Lorajmine
CAS:Lorajmine, a monochloroacetyl derivative of ajmaline, is a class Ia antiarrhythmic agent that is rapidly hydrolyzed to ajmaline by plasma and tissue esterases.Fórmula:C22H27ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:402.91Dehydelone
CAS:<p>Dehydelone(KOS-1584, R-1645, SK-10088) is a microtubule stabilizer that may be used in the treatment of non-small cell lung cancer.</p>Fórmula:C27H39NO5SCor e Forma:SolidPeso molecular:489.67GABAA receptor agonist 2
<p>Compound 4c, a potent GABAA agonist with anti-depressive effects in mouse FST/TST, shows promise in depression research.</p>Fórmula:C22H36O5Cor e Forma:SolidPeso molecular:380.52P-gp modulator 2
<p>P-gp modulator 2 (Compound 27) is a potent competitive and metabotropic P-glycoprotein (P-gp) modulator.</p>Fórmula:C22H20BrN3O4Cor e Forma:SolidPeso molecular:470.32hURAT1 inhibitor 2
CAS:<p>hURAT1 inhibitor 2 (Compound 5) is an inhibitor of hURAT1 (uric acid transporter 1, SLC22A12) with an IC50 of 18 nM. It also exhibits some inhibitory activity against OATP1B1, with an IC50 of 0.73 μM. hURAT1 inhibitor 2 can be used in research related to hyperuricemia, gout, and other diseases associated with abnormal uric acid metabolism.</p>Fórmula:C17H11Br2FO3Cor e Forma:SolidPeso molecular:442.074LY 215490
CAS:<p>LY 215490 is a selective AMPA receptor antagonist with neuroprotective properties in rat ischemia.</p>Fórmula:C13H21N5O2Pureza:98%Cor e Forma:SolidPeso molecular:279.34TRPC4/5-IN-1
<p>TRPC4/5-IN-1, a TRPC5/4 inhibitor with IC50s 0.54 μM/2.06 μM, targets skin inflammation and proteinuric kidney diseases.</p>Fórmula:C21H21N3OCor e Forma:SolidPeso molecular:331.41Probenecid sodium
CAS:<p>Probenecid sodium is the sodium salt of Probenecid, a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Additionally, Probenecid acts as an inhibitor of pannexin 1 channels.</p>Fórmula:C13H18NNaO4SCor e Forma:SolidPeso molecular:307.341(RS)-AMPA monohydrate
CAS:<p>(RS)-AMPA monohydrate, potent glutamate analogue, selectively activates L-glutamic acid without affecting kainic acid or NMDA receptors.</p>Fórmula:C7H12N2O5Cor e Forma:SolidPeso molecular:204.1828-Prenylchrysin
CAS:<p>8-Prenylchrysin is a C8-isopentenyl flavonoid compound. It acts as an inhibitor of P-glycoprotein (P-gp) and can be utilized in cancer research.</p>Fórmula:C20H18O4Cor e Forma:SolidPeso molecular:322.354INCB-056868
CAS:<p>INCB-056868 is the metabolite M11 of Epacadostat. It serves as a substrate for BCRP and holds potential for use in the study of metabolic diseases.</p>Fórmula:C11H13BrFN7O3SCor e Forma:SolidPeso molecular:422.23Unoprostone isopropyl
CAS:<p>Unoprostone isopropyl, a prostanoid and synthetic docosanoid, is approved for the treatment of ocular hypertension and open-angle glaucoma.</p>Fórmula:C25H44O5Pureza:98%Cor e Forma:SolidPeso molecular:424.61NSC73306
CAS:<p>NSC73306 is a thiosemicarbazone known for its role as a cell-permeable agent, exhibiting increased toxicity towards cells expressing p-glycoprotein.</p>Fórmula:C16H14N4O2SCor e Forma:SolidPeso molecular:326.373Lubeluzole dihydrochloride
CAS:<p>Lubeluzole (dihydrochloride) acts as a neuroprotective agent by blocking neuronal voltage-gated sodium channels and also affects cardiac sodium channels, exhibiting both tonic and blocking effects. This compound is considered promising in the research of antiarrhythmic agents.</p>Fórmula:C22H27Cl2F2N3O2SCor e Forma:SolidPeso molecular:506.44Kv7.2/Kv7.3 activator-1
CAS:<p>Kv7.2/Kv7.3 Activator-1 (compound 517) serves as a powerful activator of the Kv7.2/Kv7.3 channels, exhibiting an EC50 value of less than 1 µM. It holds potential for use in neurological disease research.</p>Fórmula:C19H22F2N4OCor e Forma:SolidPeso molecular:360.40PF-05661014
CAS:<p>PF-05661014, a demethylated analogue of PF-06526290, selectively inhibits Nav1.3 and Nav1.7 currents by stabilizing the inactivated state through interaction with the D4 VSD. This compound is utilized in research focused on sodium channel modulation.</p>Fórmula:C17H16N4O3S2Cor e Forma:SolidPeso molecular:388.46CFTR corrector 16
CAS:<p>CFTRcorrector 16 (Compound 39) is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR), utilized in the research of cystic fibrosis disease.</p>Fórmula:C27H26ClN5O2SCor e Forma:SolidPeso molecular:520.05SP100030 analogue 1
CAS:SP100030 analogue 1 (compound 11) is a selective transcription activation (SITA) inhibitor within the SP100030 class, capable of inhibiting XPO1-dependent upregulation of IL2 in a Jurkat-based IL2-Luc reporter assay, with an EC50 of 137 nM.Fórmula:C13H5ClF7N3OCor e Forma:SolidPeso molecular:387.64CFTR corrector 15
CAS:<p>CFTR Corrector 15 (Compound 4172) serves as a corrector for cystic fibrosis transmembrane conductance regulator (CFTR). When used in combination with VX-809, it addresses the folding defects of F508del-CFTR. CFTR Corrector 15 is also applicable in the research of cystic fibrosis.</p>Fórmula:C24H22ClN5O2SCor e Forma:SolidPeso molecular:479.98(2S,3S,11bR)-Dihydrotetrabenazine
CAS:<p>(2S,3S,11bR)-Dihydrotetrabenazine ((2S,3S,11bR)-DHTBZ) is a highly selective inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki value of 593 nM. It suppresses the vesicular transport of monoamine neurotransmitters, such as dopamine and serotonin, leading to reduced release into the synaptic cleft. This compound holds potential for research in Huntington's disease and other hyperkinetic movement disorders.</p>Fórmula:C19H29NO3Cor e Forma:SolidPeso molecular:319.44DAD dichloride
<p>DAD dichloride is a 3rd-gen photoelectric switch, blocks K+ channels, and helps in visual function research.</p>Fórmula:C26H42Cl2N6OCor e Forma:SolidPeso molecular:525.56GABAA receptor agonist 1
<p>Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.</p>Fórmula:C20H30O3Cor e Forma:SolidPeso molecular:318.45Odevixibat
CAS:<p>Odevixibat (A4250) is a selective oral inhibitor for ileal bile acid transport, potentially treating primary biliary cirrhosis.</p>Fórmula:C37H48N4O8S2Pureza:99.53% - 99.83%Cor e Forma:SolidPeso molecular:740.93SYM2206
CAS:<p>SYM2206 is a low affinity non-competitive AMPA receptor antagonist with an IC50 value of 1.6 μM.SYM2206 exhibits anticancer activity by blocking Nav1.6-mediated</p>Fórmula:C20H22N4O3Pureza:99.88%Cor e Forma:SolidPeso molecular:366.41SDZ 220-040
CAS:<p>SDZ 220-040 是一种选择性哺乳动物 NMDA 受体拮抗剂，可诱导根系生长的部分无重力模式 。</p>Fórmula:C16H16Cl2NO6PPureza:98.13%Cor e Forma:SolidPeso molecular:420.18Suzetrigine
CAS:Suzetrigine (VX-548) is an oral NaV1.8 inhibitor with analgesic properties for acute pain research.Fórmula:C21H20F5N3O4Pureza:98.08% - 99.27%Cor e Forma:SolidPeso molecular:473.39(+)-Tetrabenazine
CAS:(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-foldFórmula:C19H27NO3Pureza:98.69%Cor e Forma:SolidPeso molecular:317.42(-)-Bicuculline methobromide
CAS:<p>(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .</p>Fórmula:C21H20BrNO6Cor e Forma:WhitePeso molecular:462.29A-887826
CAS:A-887826 is a selective, orally bioavailable, and voltage-dependent Na(v1.8) channel blocker (IC50: 11 nM). It attenuates neuropathic tactile allodynia in vivo.Fórmula:C26H29ClN4O3Cor e Forma:SolidPeso molecular:480.995-Hydroxylansoprazole
CAS:<p>5-Hydroxylansoprazole (AG1908) is the active metabolite of plasma Lansoprazole, inhibits the proton pump, and is used in the study of peptic ulcers.</p>Fórmula:C16H14F3N3O3SPureza:99.00%Cor e Forma:SolidPeso molecular:385.36Umbellulone
CAS:Umbellulone is a natural product isolated from Umbellularia californica, and stimulates the TRPA1 channel in a subset of peptidergic, nociceptive neurons, activating the trigeminovascular system via this mechanism.Fórmula:C10H14OPureza:98%Cor e Forma:SolidPeso molecular:150.22Indapamide
CAS:<p>Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.</p>Fórmula:C16H16ClN3O3SPureza:98.97% - 99.83%Cor e Forma:SolidPeso molecular:365.832-AEMP TFA
CAS:<p>2-AEMP TFA is a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors. 2-AEMP is an analog of GABA.</p>Fórmula:C3H10NO3PPureza:98%Cor e Forma:SolidPeso molecular:139.091PF-06761281
CAS:<p>PF-06761281 is a partially selective sodium-coupled citrate transporter protein (NaCT/SLC13A5) inhibitor, oral, reducing plasma glucose concentration.</p>Fórmula:C13H17NO6Cor e Forma:SolidPeso molecular:283.283-Methylglutaconic acid
CAS:<p>3-Methylglutaconic acid, a primary metabolite accumulating in 3-Methylglutaconic aciduria (MGTA), induces lipid and protein oxidation, while diminishing non-enzymatic antioxidant defenses in cerebral cortex supernatants, thereby promoting oxidative stress in the cerebral cortex. This compound is utilized in research concerning brain damage diseases [1].</p>Fórmula:C6H8O4Pureza:98%Cor e Forma:SolidPeso molecular:144.13Alfadolone acetate
CAS:<p>Alfadolone acetate is a gamma-aminobutyric acid (GABA) receptor agonist.</p>Fórmula:C23H34O5Cor e Forma:SolidPeso molecular:390.51(Rac)-Lanicemine
CAS:<p>(Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker with a Ki of 0.56-2.1 μM for the NMDA receptor and IC50 values of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively. Lanicemine shows antidepressant effects [1].</p>Fórmula:C13H14N2Cor e Forma:SolidPeso molecular:198.26Verapamil EP Impurity C hydrochloride
CAS:<p>NSC-609249 hydrochloride, an impurity of Verapamil, is a calcium channel blocker with potent orally active properties. It also functions as a first-generation P-glycoprotein (P-gp) inhibitor.</p>Fórmula:C12H20ClNO2Cor e Forma:SolidPeso molecular:245.75Apcin A HCL
CAS:<p>Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to synthesize the PROTAC CP5V [1].</p>Fórmula:C10H15Cl4N5O2Pureza:99.30%Cor e Forma:SolidPeso molecular:379.07L-Cysteine S-sulfate sodium salt sesquihydrate
CAS:<p>L-Cysteine S-sulfate sodium salt sesquihydrate is a useful organic compound for research related to life sciences. The catalog number is T64782 and the CAS number is 150465-29-5.</p>Fórmula:C9H25N3Na3O17S6Cor e Forma:SolidPeso molecular:708.63Zastaprazan
CAS:<p>Zastaprazan (JP-1366, compound 6) is a potassium-competitive acid blocker and proton pump inhibitor that suppresses gastric acid secretion, indicated for GERD.</p>Fórmula:C22H26N4OPureza:99.97%Cor e Forma:SolidPeso molecular:362.48GNE-9278
CAS:<p>GNE-9278 is a highly selective NMDAR orthosteric modulator that targets the GluN1 transmembrane structural domain (TMD), enhancing peak current and agonist affinity in activated NMDAR.</p>Fórmula:C21H27N5O3SCor e Forma:SolidPeso molecular:429.54Indoxacarb
CAS:<p>Indoxacarb is an Oxadiazine insecticide.</p>Fórmula:C22H17ClF3N3O7Pureza:98%Cor e Forma:SolidPeso molecular:527.83Dexivacaine
CAS:Dexivacaine is an type of anesthetic.Fórmula:C15H22N2OCor e Forma:SolidPeso molecular:246.35(±)-Vasicine
CAS:<p>(±)-Vasicine, the racemate of Vasicine, is isolated from Peganum harmala seeds and exhibits anti-ulcer activity.</p>Fórmula:C11H12N2OPureza:98%Cor e Forma:SolidPeso molecular:188.23Filapixant
CAS:<p>Filapixant, a purinoreceptor antagonist. This compound serves as the active reference substance for Eliapixant.</p>Fórmula:C24H26F3N5O3SCor e Forma:SolidPeso molecular:521.56Fostedil
CAS:Fostedil enhances heart function, maintains blood flow during partial/total coronary occlusions, and lowers aortic pressure.Fórmula:C18H20NO3PSPureza:98%Cor e Forma:SolidPeso molecular:361.4Pazinaclone
CAS:<p>Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.</p>Fórmula:C25H23ClN4O4Pureza:97.79% - 99.07%Cor e Forma:SolidPeso molecular:478.93CGP 44532
CAS:<p>CGP 44532 a GABAB receptor agonist.</p>Fórmula:C4H12NO3PPureza:98%Cor e Forma:SolidPeso molecular:153.12T16A(inh)-C01
CAS:<p>T16A(inh)-C01 is the Ca(2+)-activated Cl(-) Channel, Ano1 class C inhibitor.</p>Fórmula:C18H16O5Pureza:98%Cor e Forma:SolidPeso molecular:312.32Motugivatrep
CAS:<p>Motugivatrep is a potent and selective TRPV1 antagonist that can be used to study TRPV1-related respiratory diseases.</p>Fórmula:C22H20F3NO3Pureza:99.22%Cor e Forma:SolidPeso molecular:403.39Gacyclidine
CAS:<p>Gacyclidine (OTO311), an NMDA receptor blocker, treats tinnitus and injuries in the brain and spinal cord.</p>Fórmula:C16H25NSPureza:99.85% - 99.92%Cor e Forma:SolidPeso molecular:263.44Phenamil methanesulfonate
CAS:<p>TRPP3 channel inhibitor</p>Fórmula:C13H16ClN7O4SPureza:98%Cor e Forma:SolidPeso molecular:401.83Pipequaline
CAS:<p>Pipequaline (PK-8165) is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic.</p>Fórmula:C22H24N2Pureza:98%Cor e Forma:SolidPeso molecular:316.44Ref: TM-T4655
Produto descontinuadoCMPDA
CAS:<p>CMPDA is a positive allosteric modulator of AMPA receptors [EC50s: 45.4 nM/63.4 nM for GluA2i/GluA2o receptor].</p>Fórmula:C16H28N2O4S2Pureza:98%Cor e Forma:SolidPeso molecular:376.53Tifenazoxide
CAS:<p>Tifenazoxide is an effective and SUR1/Kir6.2 selective KATP channels opener. Tifenazoxide has an anti-diabetic effect, can inhibit glucose-stimulated insulin release in vitro and in vivo.</p>Fórmula:C9H10ClN3O2S2Pureza:98%Cor e Forma:SolidPeso molecular:291.78HMR 1556
CAS:<p>HMR 1556 is a chromanol derivative and is an IKs blocker (IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively).</p>Fórmula:C17H24F3NO5SCor e Forma:SolidPeso molecular:411.44CGP 56999A
CAS:CGP 56999A is a GABA(B) receptor antagonist; it boosts BDNF and reduces dopamine loss in rat striatum.Fórmula:C19H30NO5PPureza:98%Cor e Forma:SolidPeso molecular:383.42Xilmenolone
CAS:<p>Xilmenolone acts as a positive allosteric modulator of the GABA_A receptor [1].</p>Fórmula:C26H37N3O2Pureza:98%Cor e Forma:SolidPeso molecular:423.59Ref: TM-T78670
Produto descontinuadoVMAT2-IN-2 tosylate
CAS:<p>VMAT2-IN-2 tosylate is a potent inhibitor of VMAT2 and is applicable in the research of tardive dyskinesia [1].</p>Fórmula:C27H36F3NO6SPureza:98%Cor e Forma:SolidPeso molecular:559.64Ref: TM-T79061
Produto descontinuadoBumetanide sodium
CAS:<p>Bumetanide sodium, a potent diuretic, blocks NKCC1 (IC50: 0.68 μM) and NKCC2 (IC50: 4.0 μM).</p>Fórmula:C17H19N2NaO5SCor e Forma:SolidPeso molecular:386.4LFS-1107
CAS:<p>LFS-1107, a reversible CRM1 inhibitor (Kd: 12.5 pM), selectively targets and eliminates ENKTL cells, offering potential for cancer research applications [1].</p>Fórmula:C12H11N5OS2Pureza:98%Cor e Forma:SolidPeso molecular:305.38Belfosdil
CAS:<p>Belfosdil is a blocker of antihypertensive calcium channel.</p>Fórmula:C27H50O7P2Pureza:98%Cor e Forma:SolidPeso molecular:548.63
