Transportador de Membranas/Canal Iónico
Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.
Subcategorias de "Transportador de Membranas/Canal Iónico"
- ABC(3 produtos)
- ATPase(93 produtos)
- Receptor de adiponectina(5 produtos)
- CFTR(64 produtos)
- Receptor CGRP(52 produtos)
- Canais de Cálcio(496 produtos)
- Canal de cloreto(49 produtos)
- Receptor GABA(336 produtos)
- Transportador de monoamina(23 produtos)
- Transportador de monocarboxilato(17 produtos)
- NKCC(2 produtos)
- NPC1L1(3 produtos)
- Cotransportador Na-K-Cl(8 produtos)
- OAT(27 produtos)
- OCT(7 produtos)
- P-gp(53 produtos)
- Canal de Potássio(277 produtos)
- Bomba de prótons(39 produtos)
- SGLT(30 produtos)
- Canal de Sódio(202 produtos)
- Canal TRP/TRPV(93 produtos)
Exibir 13 mais subcategorias
Foram encontrados 2290 produtos de "Transportador de Membranas/Canal Iónico"
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QO-58
CAS:<p>QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, danti-nociceptive effects on inflammatory pain</p>Fórmula:C18H8Cl2F4N4OPureza:99.17%Cor e Forma:SolidPeso molecular:443.18Pirmenol hydrochloride
CAS:<p>Pirmenol hydrochloride functions by inhibiting I_K.ACh through the blockade of muscarinic receptors, demonstrating a potent effect with an IC_50 value of 0.1 μM</p>Fórmula:C22H31ClN2OCor e Forma:SolidPeso molecular:374.95β-Cyfluthrin
CAS:<p>β-Cyfluthrin is a type II synthetic pyrethroid compound commonly utilized as an active ingredient in agricultural insecticide products.</p>Fórmula:C22H18Cl2FNO3Cor e Forma:SolidPeso molecular:434.29(-)-α-Pinene
CAS:<p>(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission,</p>Fórmula:C10H16Pureza:98.02% - 98.60%Cor e Forma:Colourless LiquidPeso molecular:136.23Flumazenil acid
CAS:<p>Flumazenil is an antagonist of GABAA receptor. Flumazenil acid is a metabolite of Flumazenil.</p>Fórmula:C13H10FN3O3Cor e Forma:SolidPeso molecular:275.24Tetrabenazine-d6
CAS:Tetrabenazine D6 is the deuterium-labeled Tetrabenazine. Tetrabenazine is a VMAT-inhibitor used for the treatment of hyperkinetic movement disorder.Fórmula:C19H27NO3Pureza:98%Cor e Forma:SolidPeso molecular:323.46GI-530159
CAS:<p>TREK1/2 activator, selective over TRAAK/TASK3; hyperpolarizes neurons, depresses activity (EC50 = 0.76 μM).</p>Fórmula:C27H20F6N2O2Cor e Forma:White CrystalsPeso molecular:518.45Luciferase, firefly
CAS:<p>Luciferase, firefly is a reporter gene in cellular imaging studies to quantify target gene expression levels and measure intracellular ATP content,</p>Pureza:98%Cor e Forma:SolidPeso molecular:N/AMRS1845
CAS:MRS1845 is a selective inhibitor of store-operated calcium (SOC) channel (IC50 of 1.7 μM).Fórmula:C21H22N2O6Pureza:99.69%Cor e Forma:SolidPeso molecular:398.41Tetramethrin
CAS:<p>Tetramethrin is a type I pyrethroid insecticide that affects the inactivation process of sodium channels in insect neurons, prolonged sodium currents.</p>Fórmula:C19H25NO4Pureza:98.85%Cor e Forma:White Crystals Or PowderPeso molecular:331.41Poneratoxin acetate
<p>Poneratoxin acetate is a neurotoxic peptide and modulator of NaV1.6/NaV1.7, lowering the activation threshold of voltage-gated sodium channels and causing pain.</p>Fórmula:C129H215N33O31S·xC2H4O2Cor e Forma:SolidPeso molecular:2756.35 (free base)VU041
CAS:VU041 inhibits mosquito Kir1 channels (IC50: An. gambiae 2.5μM, Ae. aegypti 1.7μM), less on mammalian Kir2.1 (12.7μM), and minimally on other Kir channels.Fórmula:C19H20F3N3OPureza:98%Cor e Forma:SolidPeso molecular:363.38(R)-Tegoprazan
CAS:<p>(R)-Tegoprazan, a benzimidazole derivative, inhibits kidney H+/K+-ATPase (IC50: 98 nM). Potential in GI disease research.</p>Fórmula:C20H19F2N3O3Cor e Forma:SolidPeso molecular:387.38PF-04856264
CAS:<p>PF-04856264 is a Nav1.7 blocker.,modulates intracellular Ca 2+ signaling and chondrocyte secretome, raises the threshold of mechanical pain analgesic.</p>Fórmula:C20H15N5O3S2Pureza:97.43%Cor e Forma:SolidPeso molecular:437.5Naspm
CAS:Naspm is a synthetic analogue of Joro spider toxin and is a antagonist iscalcium permeable AMPA (CP-AMPA) receptors.Fórmula:C22H34N4OPureza:98%Cor e Forma:SolidPeso molecular:370.53Dibucaine hydrochloride
CAS:<p>Dibucaine hydrochloride (Cinchocaine hydrochloride), a long-acting local amide anestheticsis, is usually used for surface anesthesia.</p>Fórmula:C20H30ClN3O2Pureza:99.66%Cor e Forma:White PowderPeso molecular:379.92(R)-Lercanidipine-d3 hydrochloride
CAS:(R)-lercanidipine D3 hydrochloride is a deuterium labeled (R)-Lercanidipine hydrochloride. (R)-Lercanidipine D3 (hydrochloride) is a calcium channel blocker.Fórmula:C36H42ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:651.21BI-9627 hydrochloride
CAS:<p>BIX HCl is a sodium-hydrogen exchange type 1 inhibitor.</p>Fórmula:C16H20ClF3N4O2Cor e Forma:SolidPeso molecular:392.8Triamterene D5
CAS:Triamterene D5 is a deuterium-labeled Triamterene and can block epithelial Na+ channel (ENaC) in a voltage-dependent manner, used as a mild diuretic.Fórmula:C12H11N7Pureza:98%Cor e Forma:SolidPeso molecular:258.29GYKI 53655 hydrochloride
CAS:GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.Fórmula:C19H21ClN4O3Pureza:98.02%Cor e Forma:SolidPeso molecular:388.85L-364,373
CAS:KV7.1 (KCNQ1) channel activatorFórmula:C25H20FN3OCor e Forma:SolidPeso molecular:397.44Nateglinide D5
CAS:<p>Nateglinide D5 is a deuterium labeled Nateglinide.</p>Fórmula:C19H27NO3Pureza:98%Cor e Forma:SolidPeso molecular:322.45Etifoxine
CAS:<p>Etifoxine targets β2/β3 GABAA receptors, is anxiolytic in humans/rodents, boosts GABAA, binds TSPO, aids axon regeneration, no sedative effects.</p>Fórmula:C17H17ClN2OPureza:98%Cor e Forma:SolidPeso molecular:300.78HSK16149
CAS:<p>HSK16149 is a novel ligand of voltage-gated calcium channel (VGCC) α 2 δ subunit with analgesic activity.</p>Fórmula:C12H19NO2Cor e Forma:SolidPeso molecular:209.28SDZ 220-581 Ammonium salt
CAS:<p>SDZ 220-581 Ammonium salt is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).</p>Fórmula:C16H20ClN2O5PPureza:98%Cor e Forma:SolidPeso molecular:386.77Lansoprazole-d4
CAS:Lansoprazole D4 (AG-1749 D4) is a deuterium labeled Lansoprazole. Lansoprazole is an inhibitor of proton pump which prevents the stomach from producing acid.Fórmula:C16H14F3N3O2SPureza:98%Cor e Forma:SolidPeso molecular:373.39Naminidil
CAS:Naminidil is an opener of cyanoguanidine KATP.Fórmula:C15H19N5Pureza:98%Cor e Forma:SolidPeso molecular:269.34YM-244769 dihydrochloride
CAS:YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM.Fórmula:C26H24Cl2FN3O3Pureza:98%Cor e Forma:SolidPeso molecular:516.39TGN-073
CAS:<p>TGN-073 is an enhancer of aquaporin 4 (AQP4), a water channel in astrocytes. It shows an increase in lymphatic transport in the rat brain by up to 41%.</p>Fórmula:C18H16N2O3SCor e Forma:SolidPeso molecular:340.396Cabotegravir sodium
CAS:<p>Cabotegravir sodium inhibits HIV integrase (IC50: 2.5 nM), metabolized by UGT1A1, with minimal ARV interaction.</p>Fórmula:C19H16F2N3NaO5Cor e Forma:SolidPeso molecular:427.34L-655708
CAS:<p>L-655708 is a selective and highly potent GABAA receptor reverse agonist with a Ki value of 0.45 nM.</p>Fórmula:C18H19N3O4Pureza:98.41%Cor e Forma:PowderPeso molecular:341.36Neosolaniol
CAS:Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.Fórmula:C19H26O8Pureza:98%Cor e Forma:SolidPeso molecular:382.4Bamaquimast
CAS:Bamaquimast (L 0042) is a proton pump inhibitor for the study of asthma-like immune system disorders and respiratory diseases.Fórmula:C16H21N3O3Pureza:98.47%Cor e Forma:SolidPeso molecular:303.36UBP608
CAS:<p>UBP608 selectively inhibits NMDA GluN1/GluN2A receptors, 23x more than GluN1/GluN2D.</p>Fórmula:C10H5BrO4Cor e Forma:SolidPeso molecular:269.053,3-Diethylthiacarbocyanine iodide
CAS:<p>3, 3-diethylthiacarbocyanine iodide is a cyanine dye. Can be used for photochemical methods.</p>Fórmula:C21H21IN2S2Pureza:99.79%Cor e Forma:SolidPeso molecular:492.44Flecainide
CAS:<p>Flecainide is an orally administered antiarrhythmic agent acting as a sodium channel blocker and IKr inhibitor,PSVT.</p>Fórmula:C17H20F6N2O3Pureza:99.896%Cor e Forma:SolidPeso molecular:414.34Leptin (22-56), human
CAS:Leptin(22-56),human is a peptide fragment of Leptin, which ACTS through a variety of subtypes of Ob-Rs.Fórmula:C171H298N50O56Cor e Forma:SolidPeso molecular:3950.52γ-DGG
CAS:<p>gamma-DGG is a competitive blocker of AMPA receptor.</p>Fórmula:C7H12N2O5Pureza:98%Cor e Forma:SolidPeso molecular:204.18Lansoprazole Sulfide D4
CAS:<p>Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth.Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole.</p>Fórmula:C16H14F3N3OSPureza:98%Cor e Forma:SolidPeso molecular:357.39N-Methyl-DL-aspartic acid
CAS:<p>N-Methyl-DL-aspartic acid, a glutamate analogue and NMDA receptor agonist, is utilized in neurological disease research.</p>Fórmula:C5H9NO4Pureza:99.85%Cor e Forma:SolidPeso molecular:147.13Benzocaine hydrochloride
CAS:<p>Benzocaine hydrochloride (Ethyl 4-aminobenzoate hydrochloride) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and</p>Fórmula:C9H11NO2·HClPureza:98%Cor e Forma:SolidPeso molecular:201.65Rapastinel
CAS:Rapastinel (TPPT-amide) (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.Fórmula:C18H31N5O6Pureza:97.18%Cor e Forma:SolidPeso molecular:413.47SKA-121
CAS:<p>SKA-121 is a selective KCa3.1 activator (EC50s: 109 nM and 4.4 μM for KCa3.1 and KCa2.3, respectively).</p>Fórmula:C12H10N2OPureza:98%Cor e Forma:SolidPeso molecular:198.22Mexiletine-d6 hydrochloride
CAS:<p>Mexiletine D6 hydrochloride is a non-selective voltage-gated sodium channel blocker,is a Class IB antianhythmic.</p>Fórmula:C11H18ClNOPureza:98%Cor e Forma:SolidPeso molecular:221.76(R)-Nicardipine
CAS:<p>(R)-Nicardipine is the less active R enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).</p>Fórmula:C26H29N3O6Cor e Forma:SolidPeso molecular:479.53Jedi2
CAS:<p>Jedi2 is a Piezo1 activator rather than a specific Piezo2 activator. Jedi2 binds to the mouse Piezo1 proteins with a K d of 2770 μM [1].</p>Fórmula:C10H8O3SPureza:97.85%Cor e Forma:SolidPeso molecular:208.23Mexiletine
CAS:<p>Mexiletine is a non-selective voltage-gated sodium channel blocker.</p>Fórmula:C11H17NOPureza:98%Cor e Forma:SolidPeso molecular:179.26Evifacotrep
CAS:<p>Evifacotrep: TRPC5 antagonist for neurological disease research (WO2020061162, compound 100).</p>Fórmula:C18H12ClF4N5O2Pureza:98.6%Cor e Forma:SolidPeso molecular:441.77Bisaramil
CAS:<p>Bisaramil is a new class I antiarrhythmic agent.</p>Fórmula:C17H23ClN2O2Cor e Forma:SolidPeso molecular:322.83
