Transportador de Membranas/Canal Iónico
Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.
Subcategorias de "Transportador de Membranas/Canal Iónico"
- ABC(3 produtos)
- ATPase(93 produtos)
- Receptor de adiponectina(5 produtos)
- CFTR(64 produtos)
- Receptor CGRP(52 produtos)
- Canais de Cálcio(496 produtos)
- Canal de cloreto(49 produtos)
- Receptor GABA(336 produtos)
- Transportador de monoamina(23 produtos)
- Transportador de monocarboxilato(17 produtos)
- NKCC(2 produtos)
- NPC1L1(3 produtos)
- Cotransportador Na-K-Cl(8 produtos)
- OAT(27 produtos)
- OCT(7 produtos)
- P-gp(53 produtos)
- Canal de Potássio(277 produtos)
- Bomba de prótons(39 produtos)
- SGLT(30 produtos)
- Canal de Sódio(202 produtos)
- Canal TRP/TRPV(93 produtos)
Exibir 13 mais subcategorias
Foram encontrados 2290 produtos de "Transportador de Membranas/Canal Iónico"
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A2793
CAS:<p>A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM.</p>Fórmula:C13H12ClNO3Pureza:98.54%Cor e Forma:SolidPeso molecular:265.69MDR-652
CAS:<p>MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1) with Ki value of 11.4 nM and 23.8 nM for</p>Fórmula:C22H23ClFN3O2SPureza:99.96%Cor e Forma:SolidPeso molecular:447.95Kv2-IN-A1
CAS:<p>Kv2-IN-A1 is an inhibitor of Kv2.1 and Kv2.2.</p>Fórmula:C20H17ClN4OSPureza:98.83%Cor e Forma:SolidPeso molecular:396.89Adjudin
CAS:<p>Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.</p>Fórmula:C15H12Cl2N4OPureza:96.51% - ≥95%Cor e Forma:SolidPeso molecular:335.19Almitrine mesylate
CAS:<p>Almitrine mesylate targets Ca2+-dependent K+ channels in rat cells, used for chronic lung hypoxemia.</p>Fórmula:C28H37F2N7O6S2Pureza:99.96%Cor e Forma:CoaPeso molecular:669.76KB-R7943 mesylate
CAS:<p>KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.</p>Fórmula:C17H21N3O6S2Pureza:99.88% - ≥95%Cor e Forma:SolidPeso molecular:427.5Eperisone hydrochloride
CAS:<p>Eperisone is a skeletal muscle relaxant and a spasmolytic agent related structurally to Tolperisone.</p>Fórmula:C17H26ClNOPureza:99.80%Cor e Forma:White Or Similar To White Crystalline Powder With Peculiar Smell And Bitter TastePeso molecular:295.85Ivacaftor
CAS:<p>Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells,</p>Fórmula:C24H28N2O3Pureza:99% - 99.98%Cor e Forma:SolidPeso molecular:392.49Miltirone
CAS:<p>Miltirone is a CYPs inhibitor, it has been characterized as a low-affinity ligand for central benzodiazepine receptors.</p>Fórmula:C19H22O2Pureza:99.22% - 99.66%Cor e Forma:SolidPeso molecular:282.38α-Asarone
CAS:<p>alpha-Asarone (trans-Asarone) is a psychoactive compound with antidepressant-like activity in mice.</p>Fórmula:C12H16O3Pureza:99.64% - 99.64%Cor e Forma:Monoclinic Needles From Water Monoclinic Needles From WaterPeso molecular:208.25Levamlodipine hydrochloride
CAS:<p>Levamlodipine hydrochloride is a medication used to lower blood pressure and prevent chest pain.</p>Fórmula:C20H26Cl2N2O5Cor e Forma:SolidPeso molecular:445.34Baclofen hydrochloride
CAS:Baclofen HCL, a GABA-B agonist, treats muscle spasticity by reducing excitatory transmission.Fórmula:C10H13Cl2NO2Pureza:99.55%Cor e Forma:SolidPeso molecular:250.122Raxatrigine hydrochloride
CAS:Raxatrigine hydrochloride is a state-dependent sodium channel blocker and a Nav1.7 sodium channel inhibitor.Fórmula:C18H20ClFN2O2Pureza:98%Cor e Forma:SolidPeso molecular:350.82Ataluren
CAS:<p>Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.</p>Fórmula:C15H9FN2O3Pureza:99.16% - 99.84%Cor e Forma:SolidPeso molecular:284.24Cyclothiazide
CAS:<p>Cyclothiazide enhances AMPA receptors, prevents desensitization, and boosts glutamic acid response (EC50 = 3.8µM).</p>Fórmula:C14H16ClN3O4S2Pureza:98.23% - 99.49%Cor e Forma:Crystals From Dilute Alcohol SolidPeso molecular:389.88PF-05186462
CAS:<p>PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.</p>Fórmula:C19H10ClF4N5O3S2Pureza:99.10% - 99.37%Cor e Forma:SolidPeso molecular:531.89Mitiglinide calcium hydrate
CAS:<p>Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.</p>Fórmula:C38H52CaN2O8Pureza:98.97% - 99.96%Cor e Forma:White SolidPeso molecular:704.91Guanosine 5'-diphosphate disodium salt
CAS:<p>5'-GDP-Na2: a nucleoside diphosphate, iron mobilizer, blocks hepcidin-ferroportin, affects IL-6/stat-3.</p>Fórmula:C10H13N5Na2O11P2Pureza:99.40%Cor e Forma:White PowderPeso molecular:487.16DAAO inhibitor-1
CAS:<p>DAAO inhibitor-1 is a potent D-amino acid oxidase (DAAO) inhibitor (IC50: 0.12 μM).</p>Fórmula:C7H5FN2OPureza:97.84%Cor e Forma:SolidPeso molecular:152.13Org 25543
CAS:<p>Org 25543 is the development of an N-Acyl amino acid that selectively inhibits the glycine transporter 2 to produce analgesia in a rat model of chronic pain.</p>Fórmula:C24H32N2O4Pureza:99.13%Cor e Forma:SolidPeso molecular:412.52Amifampridine phosphate
CAS:<p>Amifampridine treats rare muscle diseases like LEMS and congenital myasthenias, targeting specific enzyme defects.</p>Fórmula:C5H10N3O4PCor e Forma:SolidPeso molecular:207.12Argireline
CAS:<p>Argireline (Acetyl hexapeptide-3) is a peptide that inhibits neurotransmitter release, reducing wrinkles.</p>Fórmula:C34H60N14O12SPureza:96.79% - 99.65%Cor e Forma:White PowderPeso molecular:888.99SG-209
CAS:<p>SG 209 is an analog of nicorandil and acts as a K+ channel opener and nitrate-free coronary vasodilator.</p>Fórmula:C10H12N2O3Pureza:99.84%Cor e Forma:SolidPeso molecular:208.21KM11060
CAS:<p>KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma</p>Fórmula:C19H17Cl2N3O2SPureza:98.86%Cor e Forma:SolidPeso molecular:422.33Rimeporide
CAS:<p>Rimeporide (EMD-87580) (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.</p>Fórmula:C11H15N3O5S2Pureza:97.66%Cor e Forma:SolidPeso molecular:333.38(R)-Lansoprazole
CAS:<p>(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor</p>Fórmula:C16H14F3N3O2SPureza:98.09% - 98.99%Cor e Forma:Brown SolidPeso molecular:369.36Cabotegravir
CAS:<p>Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (</p>Fórmula:C19H17F2N3O5Pureza:98.55% - 99.92%Cor e Forma:SolidPeso molecular:405.35PF-4840154
CAS:<p>PF-4840154: potent TrpA1 agonist; EC50 of 97 nM (rat) & 23 nM (human); triggers nociception in mice.</p>Fórmula:C26H38N6O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:466.62DL-Willardiine
CAS:<p>DL-Willardiine (2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid) is an unnatural amino acid, a derivative of glutamate.</p>Fórmula:C7H9N3O4Pureza:99.83%Cor e Forma:SolidPeso molecular:199.16Co 101244 hydrochloride
CAS:<p>Co 101244 hydrochloride (4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride) is an NR2B-containing NMDA receptor antagonist.</p>Fórmula:C21H28ClNO3Pureza:99.76%Cor e Forma:SolidPeso molecular:377.9Procyclidine hydrochloride
CAS:<p>Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.</p>Fórmula:C19H30ClNOPureza:99.24% - 99.88%Cor e Forma:Crystals From Petroleum Ether White PowderPeso molecular:323.9CTP disodium dihydrate
CAS:<p>CTP disodium dihydrate is an agonist of P2X4 purinergic receptor</p>Fórmula:C9H18N3Na2O16P3Pureza:98.51%Cor e Forma:White Crystalline PowderPeso molecular:563.15AZ194
CAS:<p>CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.</p>Fórmula:C34H31F2N3O3Pureza:99.61%Cor e Forma:SolidPeso molecular:567.62KPT185
CAS:<p>KPT185 (KPT 185) is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest.</p>Fórmula:C16H16F3N3O3Pureza:98%Cor e Forma:SolidPeso molecular:355.31JNJ 303
CAS:<p>JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).</p>Fórmula:C21H29ClN2O4SPureza:99.28%Cor e Forma:SolidPeso molecular:440.98Tetrabenazine Racemate
CAS:<p>Tetrabenazine Racemate (Rubigen) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2).</p>Fórmula:C19H27NO3Pureza:98.65% - 98.86%Cor e Forma:SolidPeso molecular:317.42Anthracene-9-carboxylic acid
CAS:<p>Anthracene-9-carboxylic acid is an inhibitor of chloride transport with a moderate to strong inhibitory action on PKA activated cardiac IcI.</p>Fórmula:C15H10O2Pureza:99.05%Cor e Forma:Yellow Cystalline PowderPeso molecular:222.24FGH10019
CAS:<p>FGH10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM).</p>Fórmula:C18H19N3O2S2Pureza:98.93%Cor e Forma:SolidPeso molecular:373.49Evenamide
CAS:<p>Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.</p>Fórmula:C16H26N2O2Pureza:96.74% - 99.15%Cor e Forma:SolidPeso molecular:278.39Trofinetide
CAS:Trofinetide (NNZ-2566) is a synthetic analog of the endogenous N-terminus tripeptide. It has been shown to be neuroprotective in animal models of brain injury.Fórmula:C13H21N3O6Pureza:98.70% - 99.50%Cor e Forma:SolidPeso molecular:315.32Prilocaine
CAS:<p>Prilocaine (NSC-40027) is a local anesthetic of the amino amide type, which acts on the sodium channel on the neuronal membrane and limits the spread of</p>Fórmula:C13H20N2OPureza:98.49%Cor e Forma:Needles SolidPeso molecular:220.31Transdermal Peptide Disulfide Acetate
<p>Transdermal Peptide acetate(888486-23-5 free base) (TD 1 (peptide) acetate) is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainly</p>Fórmula:C42H68N14O18S2Pureza:99.97%Cor e Forma:SolidPeso molecular:1121.24-Chlorophenylguanidine hydrochloride
CAS:<p>4-Chlorophenylguanidine hydrochloride is a potent inhibitor of urokinase selectivity. </p>Fórmula:C7H9Cl2N3Pureza:99.75%Cor e Forma:SolidPeso molecular:206.07HC067047 Hydrochloride(883031-03-6 free base)
CAS:HC-067047 hydrochloride, a TRPV4 antagonist, selectively inhibits human, rat, and mouse currents with IC50s: 486 nM, 133 nM, and 17 nM.Fórmula:C26H29ClF3N3O2Pureza:99.95%Cor e Forma:SolidPeso molecular:507.98Esomeprazole
CAS:<p>Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis.</p>Fórmula:C17H19N3O3SPureza:97.3%Cor e Forma:SolidPeso molecular:345.42Epaminurad
CAS:<p>Epaminurad (UR-1102) is an oral URAT1 inhibitor for gout research with a Ki of 0.057 μM, modestly affects OAT1/3.</p>Fórmula:C14H10Br2N2O3Cor e Forma:SolidPeso molecular:414.05ML335
CAS:<p>ML335 is a selective activator of TREK-1 and TREK-2.</p>Fórmula:C15H14Cl2N2O3SPureza:99.73% - 99.79%Cor e Forma:SolidPeso molecular:373.25Glibenclamide potassium
CAS:<p>Glibenclamide potassium, a more soluble form of Glibenclamide, exists as anhydrous and hydrate salts.</p>Fórmula:C23H27ClKN3O5SCor e Forma:SolidPeso molecular:532.09JNJ-26990990
CAS:<p>"JNJ-26990990: broad-spectrum anticonvulsant, less side effects than topiramate, potential for pain and depression treatment; Phase II in 2007."</p>Fórmula:C9H10N2O2S2Pureza:97.37%Cor e Forma:SolidPeso molecular:242.32Isoflurane
CAS:<p>Isoflurane (Forane) is a stable, non-explosive inhalation anesthetic that has been reported to induce caspase-3 activation.</p>Fórmula:C3H2ClF5OPureza:98%Cor e Forma:Clear Colorless Liquid LiquidPeso molecular:184.49
