Transportador de Membranas/Canal Iónico
Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.
Subcategorias de "Transportador de Membranas/Canal Iónico"
- ABC(3 produtos)
- ATPase(93 produtos)
- Receptor de adiponectina(5 produtos)
- CFTR(64 produtos)
- Receptor CGRP(51 produtos)
- Canais de Cálcio(493 produtos)
- Canal de cloreto(49 produtos)
- Receptor GABA(336 produtos)
- Transportador de monoamina(23 produtos)
- Transportador de monocarboxilato(17 produtos)
- NKCC(2 produtos)
- NPC1L1(3 produtos)
- Cotransportador Na-K-Cl(8 produtos)
- OAT(27 produtos)
- OCT(7 produtos)
- P-gp(53 produtos)
- Canal de Potássio(276 produtos)
- Bomba de prótons(39 produtos)
- SGLT(30 produtos)
- Canal de Sódio(202 produtos)
- Canal TRP/TRPV(93 produtos)
Exibir 13 mais subcategorias
Foram encontrados 2277 produtos de "Transportador de Membranas/Canal Iónico"
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ML277
CAS:<p>ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).</p>Fórmula:C23H25N3O4S2Pureza:99.35%Cor e Forma:SolidPeso molecular:471.59A2793
CAS:<p>A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM.</p>Fórmula:C13H12ClNO3Pureza:98.54%Cor e Forma:SolidPeso molecular:265.69CX614
CAS:<p>CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.</p>Fórmula:C13H13NO4Pureza:97.37%Cor e Forma:SolidPeso molecular:247.255,7-Dichlorokynurenic acid
CAS:<p>5,7-Dichlorokynurenic acid (5,7-dichlorokynurenic acid sodium) is an NMDA receptor antagonist.</p>Fórmula:C10H5Cl2NO3Pureza:99.71%Cor e Forma:SolidPeso molecular:258.06TC-I2000
CAS:<p>TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.</p>Fórmula:C23H18F4N2OPureza:99.778%Cor e Forma:SolidPeso molecular:414.4S107
CAS:<p>S107 stabilizes RyR2 by improving calstabin2 binding to mutant/PKA-phosphorylated channels.</p>Fórmula:C11H15NOSPureza:99.90%Cor e Forma:SolidPeso molecular:209.31PF-01247324
CAS:<p>PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).</p>Fórmula:C13H10Cl3N3OPureza:99.22%Cor e Forma:SolidPeso molecular:330.6Quadrol
CAS:<p>Quadrol (EDTP) is an immunostimulant, accelerated wound healing.</p>Fórmula:C14H32N2O4Pureza:99.91% - 99.92%Cor e Forma:Viscous Liquid Liquid ViscousPeso molecular:292.41Vanillyl butyl ether
CAS:<p>Vanillyl butyl ether (Butyl vanillyl ether) (VBE)is a capsaicin analogue,induce sensory irritation in humans,Vanillyl butyl ether is an alkoxy-substituted</p>Fórmula:C12H18O3Pureza:99.57%Cor e Forma:Yellowish Liquid LiquidPeso molecular:210.27VU0071063
CAS:<p>VU0071063 is a Kir6.2/SUR1 activator.</p>Fórmula:C18H22N4O2Pureza:99.33%Cor e Forma:SolidPeso molecular:326.39(2S)-6-Prenylnaringenin
CAS:<p>(2S)-6-Prenylnaringenin (6-Prenylnaringenin) is an isomer of the potent phytoestrogen, 8-prenylnaringenin.</p>Fórmula:C20H20O5Pureza:99.47%Cor e Forma:SolidPeso molecular:340.37Amifampridine phosphate
CAS:<p>Amifampridine treats rare muscle diseases like LEMS and congenital myasthenias, targeting specific enzyme defects.</p>Fórmula:C5H10N3O4PCor e Forma:SolidPeso molecular:207.12IDRA-21
CAS:IDRA-21 is a positive AMPA receptor modulator.Fórmula:C8H9ClN2O2SPureza:99.73%Cor e Forma:SolidPeso molecular:232.69Guan-fu base A hydrochloride(1394-48-5 free base)
CAS:<p>Guanfu base A HCl, an antiarrhythmic from Aconitum coreanum, inhibits CYP2D6 in humans, monkeys, and dogs.</p>Fórmula:C24H32NO6ClPureza:99.9%Cor e Forma:SolidPeso molecular:465.97Pyr10
CAS:<p>Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in TRPC3-HEK293, and 13.08 μM in BRL-2H3 cells.</p>Fórmula:C18H13F6N3O2SPureza:99.69% - 99.7%Cor e Forma:SolidPeso molecular:449.37VX-150
CAS:<p>VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (>400-fold).</p>Fórmula:C21H17F4N2O7PPureza:97.58%Cor e Forma:SolidPeso molecular:516.34Cis-ACBD
CAS:<p>Cis-ACBD (cis-1-aminocyclobutane-1,3-dicarboxylic acid) is a potent and selective N-methyl-D-aspartate receptor agonist.</p>Fórmula:C6H9NO4Pureza:99.77%Cor e Forma:SolidPeso molecular:159.14Parimifasor
CAS:<p>Parimifasor (LYC30937) is an immunomodulator, with anti-inflammatory activity.</p>Fórmula:C18H11Cl2F4N5OPureza:96.77% - 98.97%Cor e Forma:SolidPeso molecular:460.21α-Thujone
CAS:<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Fórmula:C10H16OPureza:97.02% - 98.41%Cor e Forma:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Peso molecular:152.23Eperisone hydrochloride
CAS:<p>Eperisone is a skeletal muscle relaxant and a spasmolytic agent related structurally to Tolperisone.</p>Fórmula:C17H26ClNOPureza:99.80%Cor e Forma:White Or Similar To White Crystalline Powder With Peculiar Smell And Bitter TastePeso molecular:295.85Benzamil
CAS:<p>Benzamil blocks ENaC, inhibiting sodium transport (IC50=4 nM) and binds with Kd=5 nM to bovine kidney membranes.</p>Fórmula:C13H14ClN7OPureza:99.79%Cor e Forma:SolidPeso molecular:319.75KB-R7943 mesylate
CAS:<p>KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.</p>Fórmula:C17H21N3O6S2Pureza:99.88% - ≥95%Cor e Forma:SolidPeso molecular:427.5Benzocaine xHCl(94-09-7(free base))
<p>Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).</p>Fórmula:C9H11NO2·xHClPureza:99.37%Cor e Forma:SolidPeso molecular:N/AMitiglinide calcium hydrate
CAS:<p>Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.</p>Fórmula:C38H52CaN2O8Pureza:98.97% - 99.96%Cor e Forma:White SolidPeso molecular:704.91Argireline
CAS:<p>Argireline (Acetyl hexapeptide-3) is a peptide that inhibits neurotransmitter release, reducing wrinkles.</p>Fórmula:C34H60N14O12SPureza:96.79% - 99.65%Cor e Forma:White PowderPeso molecular:888.99DAAO inhibitor-1
CAS:<p>DAAO inhibitor-1 is a potent D-amino acid oxidase (DAAO) inhibitor (IC50: 0.12 μM).</p>Fórmula:C7H5FN2OPureza:97.84%Cor e Forma:SolidPeso molecular:152.13Cholesterol myristate
CAS:<p>Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.</p>Fórmula:C41H72O2Pureza:99.65%Cor e Forma:SolidPeso molecular:597.01BRITE-338733
CAS:<p>BRITE-338733 is a novel inhibitor of ATPase. BRITE 338733 inhibits the expression of RecA in bacteria (IC50=4.7 μM) for the bacterial infections treatment.</p>Fórmula:C27H35N3O2Pureza:99.85%Cor e Forma:SolidPeso molecular:433.59Lumacaftor
CAS:<p>Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.</p>Fórmula:C24H18F2N2O5Pureza:99.48% - 99.68%Cor e Forma:SolidPeso molecular:452.41SG-209
CAS:<p>SG 209 is an analog of nicorandil and acts as a K+ channel opener and nitrate-free coronary vasodilator.</p>Fórmula:C10H12N2O3Pureza:99.84%Cor e Forma:SolidPeso molecular:208.21DQP 1105
CAS:<p>DQP 1105 is a NMDA receptor antagonist.</p>Fórmula:C29H24BrN3O4Pureza:98.6%Cor e Forma:SolidPeso molecular:558.42Drotaverine hydrochloride
CAS:<p>Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor，and is an antispasmodic drug, used to enhance cervical dilation</p>Fórmula:C24H32ClNO4Pureza:99.81%Cor e Forma:Pale-Yellow Crystalline SolidPeso molecular:433.968Chembridge-5861528
CAS:<p>Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM.</p>Fórmula:C19H23N5O3Pureza:99.97%Cor e Forma:SolidPeso molecular:369.42JNJ-17203212
CAS:<p>JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 of 65 nM and 102 nM).</p>Fórmula:C17H15F6N5OPureza:99.18%Cor e Forma:SolidPeso molecular:419.32Imidazenil
CAS:<p>Imidazenil is an modulator of GABA-A that blocks the sedative effects without lowering the convulsion threshold.</p>Fórmula:C18H12BrFN4OPureza:98.4%Cor e Forma:SolidPeso molecular:399.22GMQ hydrochloride
CAS:<p>GMQ hydrochloride, a potent ASIC modulator, activates ASIC3 at neutral pH and inhibits acid-induced peak current.</p>Fórmula:C10H12ClN5Pureza:99.64%Cor e Forma:SolidPeso molecular:237.69Gabazine free base
CAS:<p>Gabazine free base is a specific antagonist of the GABA receptor. It does not affect GABA-transaminase or glutamate-decarboxylase activities.</p>Fórmula:C15H17N3O3Cor e Forma:SolidPeso molecular:287.31AZ194
CAS:<p>CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.</p>Fórmula:C34H31F2N3O3Pureza:99.61%Cor e Forma:SolidPeso molecular:567.62Piperazine citrate
CAS:<p>Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring.</p>Fórmula:C24H46N6O14Pureza:99.8%Cor e Forma:Crystals IndicationPeso molecular:642.65Icenticaftor
CAS:<p>Icenticaftor (QBW251) is an orally active potentiator of CFTR channel.</p>Fórmula:C12H13F6N3O3Pureza:99.76%Cor e Forma:SolidPeso molecular:361.24Temgicoluril
CAS:<p>Temgicoluril (mebikar) acts on GABA Receptor.</p>Fórmula:C8H14N4O2Pureza:99.8%Cor e Forma:SolidPeso molecular:198.22Trofinetide
CAS:<p>Trofinetide (NNZ-2566) is a synthetic analog of the endogenous N-terminus tripeptide. It has been shown to be neuroprotective in animal models of brain injury.</p>Fórmula:C13H21N3O6Pureza:98.70% - 99.50%Cor e Forma:SolidPeso molecular:315.32Glibenclamide potassium
CAS:<p>Glibenclamide potassium, a more soluble form of Glibenclamide, exists as anhydrous and hydrate salts.</p>Fórmula:C23H27ClKN3O5SCor e Forma:SolidPeso molecular:532.09GSK2193874
CAS:<p>GSK2193874 was identified as a selective, orally active TRPV4 blocker.</p>Fórmula:C37H38BrF3N4OPureza:98.79% - ≥95%Cor e Forma:SolidPeso molecular:691.62AZD7507
CAS:<p>AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.</p>Fórmula:C23H27FN6O3Pureza:99.55% - 99.78%Cor e Forma:SolidPeso molecular:454.5Iptakalim Hydrochloride
CAS:<p>Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine</p>Fórmula:C9H22ClNPureza:98%Cor e Forma:SolidPeso molecular:179.731ICA-105574
CAS:<p>ICA-105574 activates hERG, enhancing peak current and shortening action potential, while modulating activation kinetics.</p>Fórmula:C19H14N2O4Pureza:98.89%Cor e Forma:SolidPeso molecular:334.33RN-1747
CAS:<p>RN-1747: TRPV4 agonist (EC50: human 0.77 μM, mouse 4.0 μM, rat 4.1 μM), TRPM8 antagonist (IC50: 4 μM).</p>Fórmula:C17H18ClN3O4SPureza:99.29%Cor e Forma:SolidPeso molecular:395.86BTS
CAS:<p>BTS (N-Tosylbenzylamine) is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .</p>Fórmula:C14H15NO2SPureza:99.45%Cor e Forma:White Crystalline SolidPeso molecular:261.34Bisaramil
CAS:<p>Bisaramil is a new class I antiarrhythmic agent.</p>Fórmula:C17H23ClN2O2Cor e Forma:SolidPeso molecular:322.83
